Members

  First name: Vincent
  Last name: Madelain
  Position: PhD student
  Email: vincent.madelain
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inserm.fr

Research interest


My research interest focuses on pharmacokinetic and viral dynamic modelling, with a PhD subject entitled "Modeling the paradigm of HIV post-treatment controllers using clinical and animal data".

Education

Degree

2015: MSc Public Health / Master 2 Santé publique: Méthodes en évaluation thérapeutique (Paris Descartes University)
2006 – 2012: Pharmacist training (Poitiers University)

Exhaustive list of publications

2017


Madelain V, Le MP, Champenois K, Charpentier C, Landman R, Joly V, Yeni P, Descamps D, Yazdanpanah Y, Peytavin G
Impact of obesity on antiretroviral pharmacokinetics and immuno-virological response in HIV-infected patients: a case-control study.
The Journal of Antimicrobial Chemotherapy 2017, 72, 1137-1146.

Madelain V, Guedj J, Mentré F, Nguyen THT, Jacquot F, Oestereich L, Kadota T, Yamada K, Taburet AM, de Lamballerie X, Raoul H
Favipiravir Pharmacokinetics in Nonhuman Primates and Insights for Future Efficacy Studies of Hemorrhagic Fever Viruses.
Antimicrobial Agents and Chemotherapy 2017, 61,

Nguyen THT, Guedj J, Anglaret X, Laouénan C, Madelain V, Taburet AM, Baize S, Sissoko D, Pastorino B, Rodallec A, Piorkowski G, Carazo S, Conde MN, Gala JL, Bore JA, Carbonnelle C, Jacquot F, Raoul H, Malvy D, de Lamballerie X, Mentré F, Jsg
Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted.
PLoS neglected tropical diseases 2017, 11, e0005389.

2016


Madelain V, Nguyen THT, Olivo A, de Lamballerie X, Guedj J, Taburet AM, Mentré F
Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials.
Clinical Pharmacokinetics 2016, 55, 907-923.

2015


Madelain V, Oestereich L, Graw F, Nguyen THT, de Lamballerie X, Mentré F, Günther S, Guedj J
Ebola virus dynamics in mice treated with favipiravir.
Antiviral Research 2015, 123, 70-77.