Antezack A. et al. Isolation and Characterization of Kingella bonacorsii sp. nov.,A Novel Kingella Species Detected in a Stable Periodontitis Subject. Pathogens. 2021 Feb 19
Continue reading…
Non classé
Publis IAME
Publis IAME
Continue reading…
The dramatic success of infectious agents comes from their ability to adapt to both immune and pharmaceutical selective pressures. To uncover the dynamics of bacterial adaptation, experimental evolution has been widely used, focusing mostly on organismal fitness. Many of the observation derived from these experiments have been captured by Fisher’s Geometric model of Adaptation (FGMA). Despite its success, this top-down phenotypic model is relatively abstract. In fact, its most important parameter, the number of independent phenotypes an organism expose to the action of natural selection, or phenotypic complexity, remains completely disconnected from a genetic perspective. More recently, bottom-up genotype to […]
Continue reading…