First name: Imane
  Last name: El Meouche
  Function: Chargée de recherche INSERM
  Email: imane.el-meouche

Research interest

Antibiotic resistance and tolerance

List of the main publications

Exhaustive list of publications


de Lastours V, El Meouche I, Chau F, Beghain J, Chevret D, Aubert-Frambourg A, Clermont O, Royer G, Bouvet O, Denamur E, Fantin B, CG
Evolution of fluoroquinolone-resistant Escherichia coli in the gut after ciprofloxacin treatment.
International journal of medical microbiology: IJMM 2022, 312, 151548.

Hobson CA, Vigue L, Naimi S, Chassaing B, Magnan M, Bonacorsi S, Gachet B, El Meouche I, Birgy A, Tenaillon O
MiniBioReactor Array (MBRA) in vitro gut model: a reliable system to study microbiota-dependent response to antibiotic treatment.
JAC-antimicrobial resistance 2022, 4, dlac077.


Langevin AM, El Meouche I, Dunlop MJ
Mapping the Role of AcrAB-TolC Efflux Pumps in the Evolution of Antibiotic Resistance Reveals Near-MIC Treatments Facilitate Resistance Acquisition.
mSphere 2020


Rossi NA, El Meouche I, Dunlop MJ
Forecasting cell fate during antibiotic exposure using stochastic gene expression.
Communications Biology 2019, 2, 259.


Romano V, Pasquale V, Lemee L, El Meouche I, Pestel-Caron M, Capuano F, Buono P, Dumontet S
Clostridioides difficile in the environment, food, animals and humans in southern Italy: Occurrence and genetic relatedness.
Comparative Immunology, Microbiology and Infectious Diseases 2018, 59, 41-46.

El Meouche I, Dunlop MJ
Heterogeneity in efflux pump expression predisposes antibiotic-resistant cells to mutation.
Science (New York, N.Y.) 2018, 362, 686-690.

Wydau-Dematteis S, El Meouche I, Courtin P, Hamiot A, Lai-Kuen R, Saubaméa B, Fenaille F, Butel MJ, Pons JL, Dupuy B, Chapot-Chartier MP, Peltier J
Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile.
mBio 2018

El Meouche I, Peltier J
Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile.
Microbial Cell (Graz, Austria) 2018, 5, 421-423.


Wang T, El Meouche I, Dunlop MJ
Bacterial persistence induced by salicylate via reactive oxygen species.
Scientific Reports 2017, 7, 43839.


El Meouche I, Siu Y, Dunlop MJ
Stochastic expression of a multiple antibiotic resistance activator confers transient resistance in single cells.
Scientific Reports 2016, 6, 19538.


Peltier J, Courtin P, El Meouche I, Catel-Ferreira M, Chapot-Chartier MP, Lemée L, Pons JL
Genomic and expression analysis of the vanG-like gene cluster of Clostridium difficile.
Microbiology (Reading, England) 2013, 159, 1510-1520.

El Meouche I, Peltier J, Monot M, Soutourina O, Pestel-Caron M, Dupuy B, Pons JL
Characterization of the SigD regulon of C. difficile and its positive control of toxin production through the regulation of tcdR.
PloS One 2013, 8, e83748.


Peltier J, Courtin P, El Meouche I, Lemée L, Chapot-Chartier MP, Pons JL
Clostridium difficile has an original peptidoglycan structure with a high level of N-acetylglucosamine deacetylation and mainly 3-3 cross-links.
The Journal of Biological Chemistry 2011, 286, 29053-29062.