Members

  First name: Antoine
  Last name: Bridier-Nahmias
  Function: Associate Professor / Maître de conférence
  Position: Associate Professor / Maître de conférence
  Email: antoine.bridier-nahmias
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inserm.fr

Research interest


  My research interest is mainly focused on viral and bacterial evolution through genomics analysis.   I am also interested in the development of new methods regarding genome wide association studies and phylodynamics inferences.

Education

Degree

2014 : PhD in Biotechnology & Biotherapy, Université Paris Diderot (PARIS 7)
2010 : Master degree in Molecular Biology, UPMC (PARIS 6)
2008 : Bachelor in Life Science, specialized in Genetics & Biochemistry, UPMC (PARIS 6)

Academic positions

2016-present: Associate Professor in Biochemistry and Bioinformatics, Medical School, Université Paris Cité (former Paris Diderot University)
2013-2016 : Teaching Assistant in Biology, CNAM (Conservatoire National des Arts et Métiers)


Research training (post doctoral)

2016-present: Associate Professor in Biochemistry and Bioinformatics, Medical School, Paris Diderot University
2015-2016 : Post Doctoral fellow, Bioinformatics department, EA-4627 Conservatoire National des Arts et Métiers
2014-2016 : Post-Doctoral fellow, U944/UMR7212, Molecular Pathology and Virology

List of the main publications

Coppée R, Blanquart F, Jary A, Leducq V, Ferré VM, Franco Yusti AM, Daniel L, Charpentier C, Lebourgeois S, Zafilaza K, Calvez V, Descamps D, Marcelin AG, Visseaux B, Bridier-Nahmias A
Phylodynamics of SARS-CoV-2 in France, Europe, and the world in 2020.
eLife 2023, 12, e82538.

Beghain J, Bridier-Nahmias A, Le Nagard H, Denamur E, Clermont O
ClermonTyping: an easy-to-use and accurate in silico method for Escherichia genus strain phylotyping.
Microbial Genomics 2018, 4, e000192.

Bridier-Nahmias A, Tchalikian-Cosson A, Baller JA, Menouni R, Fayol H, Flores A, Saïb A, Werner M, Voytas DF, Lesage P
Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration.
Science (New York, N.Y.) 2015, 348, 585-588.


Exhaustive list of publications

2024


Guilbaud R, Franco Yusti AM, Leducq V, Zafilaza K, Bridier-Nahmias A, Todesco E, Soulie C, Fauchois A, Le Hingrat Q, Kramer L, Goulenok T, Salpin M, Daugas E, Dorent R, Ottaviani S, Zalcman G, Ghosn J, Choquet S, Cacoub P, Amoura Z, Barroux B, Pourcher V, Spano JP, Louet M, Marcelin AG, Calvez V, Charpentier C, Descamps D, Marot S, Ferré VM, Coppée R
Higher Levels of SARS-CoV-2 Genetic Variation in Immunocompromised Patients: A Retrospective Case-Control Study.
The Journal of Infectious Diseases 2024, 229, 1041-1049.

d'Humières C, Delavy M, Alla L, Ichou F, Gauliard E, Ghozlane A, Levenez F, Galleron N, Quinquis B, Pons N, Mullaert J, Bridier-Nahmias A, Condamine B, Touchon M, Rainteau D, Lamazière A, Lesnik P, Ponnaiah M, Lhomme M, Sertour N, Devente S, Docquier JD, Bougnoux ME, Tenaillon O, Magnan M, Ruppé E, Grall N, Duval X, Ehrlich D, Mentré F, Denamur E, Rocha EPC, Le Chatelier E, Burdet C, PrediRes study group
Perturbation and resilience of the gut microbiome up to 3 months after β-lactams exposure in healthy volunteers suggest an important role of microbial β-lactamases.
Microbiome 2024, 12, 50.

2023


Jacquier H, Assao B, Chau F, Guindo O, Condamine B, Magnan M, Bridier-Nahmias A, Sayingoza-Makombe N, Moumouni A, Page AL, Langendorf C, Coldiron ME, Denamur E, de Lastours V
Faecal carriage of extended-spectrum β-lactamase-producing Escherichia coli in a remote region of Niger.
The Journal of Infection 2023, 87, 199-209.

Senelle G, Sahal MR, La K, Billard-Pomares T, Marin J, Mougari F, Bridier-Nahmias A, Carbonnelle E, Cambau E, Refrégier G, Guyeux C, Sola C
Towards the reconstruction of a global TB history using a new pipeline "TB-Annotator".
Tuberculosis (Edinburgh, Scotland) 2023, 143S, 102376.

Coppée R, Chenane HR, Bridier-Nahmias A, Tcherakian C, Catherinot E, Collin G, Lebourgeois S, Visseaux B, Descamps D, Vasse M, Farfour E
Temporal dynamics of RSV shedding and genetic diversity in adults during the COVID-19 pandemic in a French hospital, early 2021.
Virus Research 2023, 323, 198950.

Coppée R, Blanquart F, Jary A, Leducq V, Ferré VM, Franco Yusti AM, Daniel L, Charpentier C, Lebourgeois S, Zafilaza K, Calvez V, Descamps D, Marcelin AG, Visseaux B, Bridier-Nahmias A
Phylodynamics of SARS-CoV-2 in France, Europe, and the world in 2020.
eLife 2023, 12, e82538.

2022


Guk J, Bridier-Nahmias A, Magnan M, Grall N, Duval X, Clermont O, Ruppé E, d'Humières C, Tenaillon O, Denamur E, Mentré F, Guedj J, Burdet C, CEREMI study group
Modeling the bacterial dynamics in the gut microbiota following an antibiotic-induced perturbation.
CPT: pharmacometrics & systems pharmacology 2022, 11, 906-918.

Leducq V, Jary A, Bridier-Nahmias A, Daniel L, Zafilaza K, Damond F, Goldstein V, Duval A, Blanquart F, Calvez V, Descamps D, Marcelin AG, Visseaux B
Nosocomial transmission clusters and lineage diversity characterized by SARS-CoV-2 genomes from two large hospitals in Paris, France, in 2020.
Scientific Reports 2022, 12, 1094.

Fromentin M, Bridier-Nahmias A, Legoff J, Mercier-Delarue S, Ranger N, Vuillard C, Do Vale J, Zucman N, Alberdi A, Ricard JD, Roux D
The 16S rRNA lung microbiome in mechanically ventilated patients: a methodological study.
Experimental Lung Research 2022, 48, 23-34.

Bizot E, Cointe A, Bidet P, Mariani-Kurkdjian P, Hobson CA, Courroux C, Liguori S, Bridier-Nahmias A, Magnan M, Merimèche M, Caméléna F, Berçot B, Weill FX, Lefèvre S, Bonacorsi S, Birgy A
Azithromycin Resistance in Shiga Toxin-Producing Escherichia coli in France between 2004 and 2020 and Detection of mef(C)-mph(G) Genes.
Antimicrobial Agents and Chemotherapy 2022, 66, e0194921.

2021


Tarhini H, Recoing A, Bridier-Nahmias A, Rahi M, Lambert C, Martres P, Lucet JC, Rioux C, Bouzid D, Lebourgeois S, Descamps D, Yazdanpanah Y, Le Hingrat Q, Lescure FX, Visseaux B
Long-Term Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectiousness Among Three Immunocompromised Patients: From Prolonged Viral Shedding to SARS-CoV-2 Superinfection.
The Journal of Infectious Diseases 2021, 223, 1522-1527.

Bridier-Nahmias A, Launay A, Bleibtreu A, Magnan M, Walewski V, Chatel J, Dion S, Robbe-Saule V, Clermont O, Norel F, Denamur E, Tenaillon O
Escherichia coli Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play.
mSphere 2021, 6, e01176-20.

Peiffer-Smadja N, Bridier-Nahmias A, Ferré VM, Charpentier C, Garé M, Rioux C, Allemand A, Lavallée P, Ghosn J, Kramer L, Descamps D, Yazdanpanah Y, Visseaux B
Emergence of E484K Mutation Following Bamlanivimab Monotherapy among High-Risk Patients Infected with the Alpha Variant of SARS-CoV-2.
Viruses 2021, 13, 1642.

2020


Cointe A, Birgy A, Bridier-Nahmias A, Mariani-Kurkdjian P, Walewski V, Lévy C, Cohen R, Fach P, Delannoy S, Bidet P, Bonacorsi S
Escherichia coli O80 hybrid pathotype strains producing Shiga toxin and ESBL: molecular characterization and potential therapeutic options.
The Journal of Antimicrobial Chemotherapy 2020, 75, 537-542.

2019


Clermont O, Dixit OVA, Vangchhia B, Condamine B, Dion S, Bridier-Nahmias A, Denamur E, Gordon D
Characterization and rapid identification of phylogroup G in Escherichia coli, a lineage with high virulence and antibiotic resistance potential.
Environmental Microbiology 2019, 21, 3107-3117.

Burdet C, Grall N, Linard M, Bridier-Nahmias A, Benhayoun M, Bourabha K, Magnan M, Clermont O, d'Humières C, Tenaillon O, Denamur E, Massias L, Tubiana S, Alavoine L, Andremont A, Mentré F, Duval X, CEREMI Group
Ceftriaxone and Cefotaxime Have Similar Effects on the Intestinal Microbiota in Human Volunteers Treated by Standard-Dose Regimens.
Antimicrobial Agents and Chemotherapy 2019, 63, e02244-18.

2018


Beghain J, Bridier-Nahmias A, Le Nagard H, Denamur E, Clermont O
ClermonTyping: an easy-to-use and accurate in silico method for Escherichia genus strain phylotyping.
Microbial Genomics 2018, 4, e000192.

Ghalayini M, Launay A, Bridier-Nahmias A, Clermont O, Denamur E, Lescat M, Tenaillon O
Evolution of a Dominant Natural Isolate of Escherichia coli in the Human Gut over the Course of a Year Suggests a Neutral Evolution with Reduced Effective Population Size.
Applied and Environmental Microbiology 2018, 84, e02377-17.

2016


Lesage P, Bétermier M, Bridier-Nahmias A, Chandler M, Chambeyron S, Cristofari G, Gilbert N, Quesneville H, Vaury C, Volff JN
International Congress on Transposable elements (ICTE 2016) in Saint Malo: mobile elements under the sun of Brittany..
Mobile DNA 2016, 7, 19.

2015


Beauclair G, Bridier-Nahmias A, Zagury JF, Saïb A, Zamborlini A
JASSA: a comprehensive tool for prediction of SUMOylation sites and SIMs..
Bioinformatics (Oxford, England) 2015, 31, 3483-3491.

Bridier-Nahmias A, Tchalikian-Cosson A, Baller JA, Menouni R, Fayol H, Flores A, Saïb A, Werner M, Voytas DF, Lesage P
Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration.
Science (New York, N.Y.) 2015, 348, 585-588.

2012


Servant G, Pinson B, Tchalikian-Cosson A, Coulpier F, Lemoine S, Pennetier C, Bridier-Nahmias A, Todeschini AL, Fayol H, Daignan-Fornier B, Lesage P
Tye7 regulates yeast Ty1 retrotransposon sense and antisense transcription in response to adenylic nucleotides stress..
Nucleic acids research 2012, 40, 5271-5282.

Bridier-Nahmias A, Lesage P
Two large-scale analyses of Ty1 LTR-retrotransposon de novo insertion events indicate that Ty1 targets nucleosomal DNA near the H2A/H2B interface..
Mobile DNA 2012, 3, 22.

Beauclair G, Tchalikian-Cosson A, Bridier-Nahmias A, Zamborlini A, Lesage P, Saïb A
Ancrage chromatinien et intégration rétrovirale : implication des protéines IN et Gag..
Virologie (Montrouge, France) 2012, 16, 73-84.

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