Members
![]() | First name: Béatrice Last name: Bercot Function: Clinical Microbiologist, MD, PHD, Position: Full Professor Email: beatrice.bercot aphp.fr |
Research interest
Research in antibiotic resistance
My research activities are focused since 20 years on antibiotic resistance focus on therapeutic strategies especially in aminoglycosides resistance (experience in genetic mobile element, expression of genes in integron structure) in Gram negative bacilli and multidrug resistant N. gonorrhoeae.
It involves close collaboration between clinical bacteriologists, infectious disease clinicians and orthopedics to combine task forces together.
Education
Degree
2014: Research Director degree (HDR), Paris Diderot University
2001: PhD in Microbiology, Paris Descartes University
1993: Medical Doctor and specialisation in Clinical Biology, Paris Descartes University
1994: Master of Sc in Microbiology and Molecular Biology, Paris Descartes University
1982-1988 : First and second cycle of Medical Scool, Nancy University
2001: PhD in Microbiology, Paris Descartes University
1993: Medical Doctor and specialisation in Clinical Biology, Paris Descartes University
1994: Master of Sc in Microbiology and Molecular Biology, Paris Descartes University
1982-1988 : First and second cycle of Medical Scool, Nancy University
Academic positions
2018-Present: Professor in Bacteriology – Head of Bacteriology Laboratory, St Louis-Lariboisière Hospital, AP-HP Nord Paris Cité University, Paris
2017-Present: Director of Associated Laboratory to the French National Reference Center for bacterial STI (gonorrhoea), APHP, St Louis Hospital
2004-2018: Associate Professor in Bacteriology, Medical School, Paris-Diderot University
1995-1999: Assistant Professor in Bacteriology, Medical School, Paris-Diderot University
1991-1995: Resident in Biology, APHP, Paris Diderot University
1988-1990: Resident in Medecine, Nancy University
2017-Present: Director of Associated Laboratory to the French National Reference Center for bacterial STI (gonorrhoea), APHP, St Louis Hospital
2004-2018: Associate Professor in Bacteriology, Medical School, Paris-Diderot University
1995-1999: Assistant Professor in Bacteriology, Medical School, Paris-Diderot University
1991-1995: Resident in Biology, APHP, Paris Diderot University
1988-1990: Resident in Medecine, Nancy University
Research training (post doctoral)
2014-Present: Researcher at University Paris Cité, Mixte Unit of Research Inserm-University, INSERM-UMR 1137, IAME, Team EvREST, Pr Denamur, Paris.
2012-2014: Researcher at University Paris-Diderot Research, EA3964 EA3964 Research Team, Pr Bruno Fantin, Paris.
2008-2012: Postdoctoral fellow at University Paris XI, Inserm Unit 914 – Emerging antibiotic resistance, Pr Nordmann, Paris
2003-2007: Collaborations Dr Mazel, Pasteur Unit, CNRS UMR3525, Paris
1997-2003: Researcher at INSERM-E004 Research Unit – Molecular Research of antibiotics, University Pierre and Marie Curie (UPMC), Pr Gutmann, Paris
2012-2014: Researcher at University Paris-Diderot Research, EA3964 EA3964 Research Team, Pr Bruno Fantin, Paris.
2008-2012: Postdoctoral fellow at University Paris XI, Inserm Unit 914 – Emerging antibiotic resistance, Pr Nordmann, Paris
2003-2007: Collaborations Dr Mazel, Pasteur Unit, CNRS UMR3525, Paris
1997-2003: Researcher at INSERM-E004 Research Unit – Molecular Research of antibiotics, University Pierre and Marie Curie (UPMC), Pr Gutmann, Paris
List of the main publications
Exhaustive list of publications
2022
Gras J, Villar-Fernandez S, Baylac P, Xhaard A, Valade S, Camelena F, Bercot B, Touratier S, de Fontbrune FS, Molina JM, Lafaurie M
Successful cefiderocol therapy of severe infections due to difficult-to-treat Pseudomonas aeruginosa in two allogeneic hematopoietic stem cell transplantation recipients.
Annals of Hematology 2022, 101, 1365-1367.
Mizrahi A, Chat L, Danjean M, Mory C, Nguyen Van JC, de Ponfilly GP, Caméléna F, Le Monnier A, Bercot B, Birgy A, Jacquier H, Pilmis B
Inoculum effect of Enterobacterales co-expressing OXA-48 and CTX-M on the susceptibility to ceftazidime/avibactam and meropenem.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2022, 41, 853-858.
Sadowski E, Bercot B, Chauffour A, Gomez C, Varon E, Mainardis M, Sougakoff W, Mayer C, Sachon E, Anquetin G, Aubry A
Lipophilic quinolone derivatives: Synthesis and in vitro antibacterial evaluation.
Bioorganic & Medicinal Chemistry Letters 2022, 55, 128450.
Hobson CA, Pierrat G, Tenaillon O, Bonacorsi S, Bercot B, Jaouen E, Jacquier H, Birgy A
Klebsiella pneumoniae Carbapenemase Variants Resistant to Ceftazidime-Avibactam: an Evolutionary Overview.
Antimicrobial Agents and Chemotherapy 2022, 66, e0044722.
Rahib D, Bercot B, Delagreverie H, Gabassi A, Delaugerre C, Salord H, Icard V, Le Thi TT, Leveau B, Khiri H, Digne J, Didelot MN, Pisoni A, Tuaillon E, Lydié N, Vandentorren S
Online self-sampling kits for human immunodeficiency virus and other sexually transmitted infections: Feasibility, positivity rates, and factors associated with infections in France.
International journal of STD & AIDS 2022, 33, 355-362.
2021
Delory T, Goujon A, Masson-Lecomte A, Arias P, Laurancon-Fretar A, Bercot B, Mongiat-Artus P, Molina JM, Lafaurie M
Fosfomycin-trometamol (FT) or fluoroquinolone (FQ) as single-dose prophylaxis for transrectal ultrasound-guided prostate biopsy (TRUS-PB): A prospective cohort study.
International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 2021, 102, 269-274.
Péan de Ponfilly G, Chauvin A, Salmona M, Benmansour H, Bercot B, Camelena F, Courbin V, Eyer X, Lecorche E, Mougari F, Munier AL, Revue E, LeGoff J, Cambau E, Jacquier H
Impact of a 24/7 multiplex-PCR on the management of patients with confirmed viral meningitis.
The Journal of Infection 2021, 83, 650-655.
2020
Mehlen M, Saunier V, de Barbeyrac B, Gaboriau T, Bébéar C, Bercot B, Castor C, Levesque D, Cazanave C, Puges M
Keep an eye on Neisseria gonorrhoeae.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020
Jacquier H, Vironneau P, Dang H, Verillaud B, Lamers G, Herman P, Vicaut E, Tessier N, Bidet P, Varon E, Van Den Abbeele T, Cambau E, Bercot B, Kania R
Bacterial biofilm in adenoids of children with chronic otitis media. Part II: a case-control study of nasopharyngeal microbiota, virulence, and resistance of biofilms in adenoids.
Acta Oto-Laryngologica 2020, 140, 220-224.
Hobson CA, Bonacorsi S, Jacquier H, Choudhury A, Magnan M, Cointe A, Bercot B, Tenaillon O, Birgy A
KPC Beta-Lactamases Are Permissive to Insertions and Deletions Conferring Substrate Spectrum Modifications and Resistance to Ceftazidime-Avibactam.
Antimicrobial Agents and Chemotherapy 2020, 64, e01175-20.
Jacquier H, Miltgen G, Hoarau D, Kumanski S, Rollot O, Bruniquet S, Ndeikoundam N, Li Pat-Yuen G, Belmonte O, Bercot B, Roquebert B
Molecular epidemiology of Neisseria gonorrhoeae clinical isolates in Reunion and Mayotte.
Sexually Transmitted Infections 2020, 96, 478-479.
Lafaurie M, d'Anglejan E, Donay JL, Glotz D, Sarfati E, Mimoun M, Legrand M, Oksenhendler E, Bagot M, Valade S, Bercot B, Molina JM
Utility of anaerobic bottles for the diagnosis of bloodstream infections.
BMC infectious diseases 2020, 20, 142.
Itodo OA, Viriot D, Velter A, Leon L, Dupin N, Bercot B, Goubard A, Lassau F, Fouere S, Martinet P, Tosini W, Florence S, RftROotFNPHA(PF, Lot F, Ndeikoundam Ngangro N
Trends and determinants of condomless sex in gonorrhoea patients diagnosed in France through the sentinel surveillance network ResIST, 2005-2014.
BMC public health 2020, 20, 1620.
2019
Kania R, Vironneau P, Dang H, Bercot B, Cambau E, Verillaud B, Camous D, Lamers G, Herman P, Vicaut E, Tessier N, Van Den Abbeele T
Bacterial biofilm in adenoids of children with chronic otitis media. Part I: a case control study of prevalence of biofilms in adenoids, risk factors and middle ear biofilms.
Acta Oto-Laryngologica 2019, 139, 345-350.
2018
Gautier G, Guillard T, Podac B, Bercot B, Vernet-Garnier V, de Champs C
Detection of different classes of carbapenemases: Adaptation and assessment of a phenotypic method applied to Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter baumannii, and proposal of a new algorithm.
Journal of Microbiological Methods 2018, 147, 26-35.
Molina JM, Charreau I, Chidiac C, Pialoux G, Cua E, Delaugerre C, Capitant C, Rojas-Castro D, Fonsart J, Bercot B, Bébéar C, Cotte L, Robineau O, Raffi F, Charbonneau P, Aslan A, Chas J, Niedbalski L, Spire B, Sagaon-Teyssier L, Carette D, Mestre SL, Doré V, Meyer L, AISG
Post-exposure prophylaxis with doxycycline to prevent sexually transmitted infections in men who have sex with men: an open-label randomised substudy of the ANRS IPERGAY trial.
The Lancet. Infectious Diseases 2018, 18, 308-317.
Harris SR, Cole MJ, Spiteri G, Sánchez-Busó L, Golparian D, Jacobsson S, Goater R, Abudahab K, Yeats CA, Bercot B, Borrego MJ, Crowley B, Stefanelli P, Tripodo F, Abad R, Aanensen DM, Unemo M, EGsg
Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey.
The Lancet. Infectious Diseases 2018, 18, 758-768.
Caméléna F, Cointe A, Mathy V, Hobson C, Doit C, Bercot B, Decré D, Podglajen I, Dortet L, Monjault A, Bidet P, Bonacorsi S, Birgy A
Within-a-Day Detection and Rapid Characterization of Carbapenemase by Use of a New Carbapenem Inactivation Method-Based Test, CIMplus.
Journal of Clinical Microbiology 2018, 56,
Poncin T, Fouere S, Braille A, Camelena F, Agsous M, Bebear C, Kumanski S, Lot F, Mercier-Delarue S, Ngangro NN, Salmona M, Schnepf N, Timsit J, Unemo M, Bercot B
Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017.
Euro Surveillance: Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin 2018, 23,
Golparian D, Rose L, Lynam A, Mohamed A, Bercot B, Ohnishi M, Crowley B, Unemo M
Multidrug-resistant Neisseria gonorrhoeae isolate, belonging to the internationally spreading Japanese FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, Ireland, August 2018.
Euro Surveillance: Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin 2018, 23,
2017
Micaëlo M, Goubard A, La Ruche G, Denamur E, Tenaillon O, Cambau E, Jacquier H, Bercot B
Molecular epidemiology of penicillinase-producing Neisseria gonorrhoeae isolates in France.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2017, 23, 968-973.
Mougari F, Loiseau J, Veziris N, Bernard C, Bercot B, Sougakoff W, Jarlier V, Raskine L, Cambau E, FNRCfM
Evaluation of the new GenoType NTM-DR kit for the molecular detection of antimicrobial resistance in non-tuberculous mycobacteria.
The Journal of Antimicrobial Chemotherapy 2017, 72, 1669-1677.
2016
Belkacem A, Jacquier H, Goubard A, Mougari F, La Ruche G, Patey O, Micaëlo M, Semaille C, Cambau E, Bercot B
Molecular epidemiology and mechanisms of resistance of azithromycin-resistant Neisseria gonorrhoeae isolated in France during 2013-14.
The Journal of Antimicrobial Chemotherapy 2016, 71, 2471-2478.
de Curraize C, Kumanski S, Micaëlo M, Fournet N, La Ruche G, Meunier F, Amarsy R, Jacquier H, Cambau E, Goubard A, Bercot B
Ceftriaxone-Resistant Neisseria gonorrhoeae Isolates (2010 to 2014) in France Characterized by Using Whole-Genome Sequencing.
Antimicrobial Agents and Chemotherapy 2016, 60, 6962-6964.
2014
Jost C, Bercot B, Jacquier H, Raskine L, Barranger E, Mouchnino G, Cambau E
Xpert GBS assay for rapid detection of group B streptococcus in gastric fluid samples from newborns.
Journal of Clinical Microbiology 2014, 52, 657-659.
La Ruche G, Goubard A, Bercot B, Cambau E, Semaille C, Sednaoui P
Gonococcal infections and emergence of gonococcal decreased susceptibility to cephalosporins in France, 2001 to 2012.
Euro Surveillance: Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin 2014, 19,
Bercot B, Belkacem A, Goubard A, Mougari F, Sednaoui P, La Ruche G, Cambau E
High-level azithromycin-resistant Neisseria gonorrhoeae clinical isolate in France, March 2014.
Euro Surveillance: Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin 2014, 19,
2013
Jacquier H, Birgy A, Le Nagard H, Mechulam Y, Schmitt E, Glodt J, Bercot B, Petit E, Poulain J, Barnaud G, Gros PA, Tenaillon O
Capturing the mutational landscape of the beta-lactamase TEM-1.
Proceedings of the National Academy of Sciences of the United States of America 2013, 110, 13067–13072.
2012
Bercot B, Nordmann P, Drancourt M, Poirel L
Chromosome-encoded extended-spectrum class A β-lactamase MIN-1 from Minibacterium massiliensis.
Antimicrobial Agents and Chemotherapy 2012, 56, 4009-4012.
2009
Bercot B, Kannengiesser C, Oudin C, Grandchamp B, Sanson-le Pors MJ, Mouly S, Elbim C
First description of NOD2 variant associated with defective neutrophil responses in a woman with granulomatous mastitis related to corynebacteria.
Journal of Clinical Microbiology 2009, 47, 3034-3037.
Reviewer for Microbial Drug Resistance, f1000Research, DMID, J of infect, J of Microbiol, Jone Bone Spine, ..
Director of the National Reference Center for Gonococci since 2017 (Molecular typing and screening for resistance to b-lactams, quinolones and azithromycin resistance in N. gonorrhoeae)