Members
![]() | First name: Bruno Last name: Fantin Function: Professor of internal medicine Position: Head of Medicine Email: bruno.fantin inserm.fr |
Research interest
Our research project relies on the study of the relationship between antibiotics and bacterial resistance with a double aspect. On one hand, we investigate the impact of antibiotic exposure on the selection of antibiotic resistance among bacteria within foci of infection but most of all among commensal flora ; on the other hand we investigate the impact of a specific mechanism of resistance on the in vivo activity of antiibotics in bacterial foci of infection in terms of bactericidal activity of the antibiotics, selection of resistant mutants and in terms of fitness of resistant strains as compared with susceptible parental strains.
The strength of our activity is to have set up a double approach allowing us to investigate this public health issue : on one hand, prospective clinical investigations allowing the study of the impact of antibiotic treatment in various populations : healthy volunteers, outpatients at admission, inpatients ; on the other hand, our recognized expertise on experimental models of animal infections and pharmacokinetic/pharmacodynamic (PK/PD) approach allowed us to study the in vivo impact of a mechanims of resistance clinically relevant on antibiotics activity and fitness of resistant bacterial strains.
Education
Degree
Hospital
– 1981: Intern (Assistance Publique-Hôpitaux de Paris)
– 1989: Assistant Professor (Assistance Publique-Hôpitaux de Paris)
– 1997: Head of the Unit of Internal Medicine, Beaujon Hospital (Assistance Publique-Hôpitaux de Paris)
– 2000: Head of the Department of Internal Medicine, Beaujon Hospital (Assistance Publique-Hôpitaux de Paris)
University
– 1986: M. D. Faculty of Medicine Xavier-Bichat, University Paris 7.
– 1992: Ph. D. in Clinical and Experimental Pharmacology, University Paris 7.
– 1995: Research directorship, University Paris 7.
– 1996: Professor, Internal Medicine, University Paris 7.
– 1981: Intern (Assistance Publique-Hôpitaux de Paris)
– 1989: Assistant Professor (Assistance Publique-Hôpitaux de Paris)
– 1997: Head of the Unit of Internal Medicine, Beaujon Hospital (Assistance Publique-Hôpitaux de Paris)
– 2000: Head of the Department of Internal Medicine, Beaujon Hospital (Assistance Publique-Hôpitaux de Paris)
University
– 1986: M. D. Faculty of Medicine Xavier-Bichat, University Paris 7.
– 1992: Ph. D. in Clinical and Experimental Pharmacology, University Paris 7.
– 1995: Research directorship, University Paris 7.
– 1996: Professor, Internal Medicine, University Paris 7.
Academic positions
– 1986: M. D. Faculty of Medicine Xavier-Bichat, University Paris 7.
– 1992: Ph. D. in Clinical and Experimental Pharmacology, University Paris 7.
– 1995: Research directorship, University Paris 7.
– 1996: Professor, Internal Medicine, University Paris 7.
– 1992: Ph. D. in Clinical and Experimental Pharmacology, University Paris 7.
– 1995: Research directorship, University Paris 7.
– 1996: Professor, Internal Medicine, University Paris 7.
Research training (post doctoral)
– 1985-1986 : Student, INSERM U 13, Professor Pocidalo, Paris.
– 1987-1988: Research Fellow, Professor Craig Laboratory, University of Wisconsin, Madison, USA.
– 1992-1994: Research Fellow, INSERM U 13, Professor Carbon, Paris.
– 1994-2000: Responsible for a research group, INSERM, EMI9933.
– 2001-2002: Director, INSERM EMI 9933.
– 2005-2013 : Director, EA3964, University Paris 7.
– 1987-1988: Research Fellow, Professor Craig Laboratory, University of Wisconsin, Madison, USA.
– 1992-1994: Research Fellow, INSERM U 13, Professor Carbon, Paris.
– 1994-2000: Responsible for a research group, INSERM, EMI9933.
– 2001-2002: Director, INSERM EMI 9933.
– 2005-2013 : Director, EA3964, University Paris 7.
List of the main publications
Exhaustive list of publications
2022
Sokal A, Chawki S, Nguyen Y, Sauvanet A, Ponsot P, Maire F, Fantin B, de Lastours V
Specificities of acute cholangitis in patients with cancer: a retrospective comparative study of 130 episodes.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2022, 41, 143-146.
Rossi G, Nguyen Y, Lafont E, Rossi B, Canouï E, Roux O, Dokmak S, Bert F, Fantin B, Lefort A
Large retrospective study analysing predictive factors of primary treatment failure, recurrence and death in pyogenic liver abscesses.
Infection 2022, 50, 1205-1215.
Rollin G, Rossi B, Brisse S, Decré D, Leflon-Guibout V, Bert F, Hoffmann I, Decousser JW, Fantin B, Lefort A
Spontaneous and postsurgical/traumatic Klebsiella pneumoniae meningitis: two distinct clinico-microbiological entities.
International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 2022, 114, 185-191.
de Lastours V, El Meouche I, Chau F, Beghain J, Chevret D, Aubert-Frambourg A, Clermont O, Royer G, Bouvet O, Denamur E, Fantin B, CG
Evolution of fluoroquinolone-resistant Escherichia coli in the gut after ciprofloxacin treatment.
International journal of medical microbiology: IJMM 2022, 312, 151548.
2021
Chawki S, Sokal A, Duprilot M, Henry A, Leflon-Guibout V, Nicolas-Chanoine MH, Fantin B, de Lastours V
Temocillin as an alternative treatment for acute bacterial cholangitis: a retrospective microbiology susceptibility-based study of 140 episodes.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2021
Vanjak A, Canouï E, Honsel V, Argy N, Houzé S, Roux O, Fantin B
Early primary toxoplasmosis transmitted by liver graft: A case report.
Infectious Diseases Now 2021, 51, 315-316.
Delforge J, Sovaila S, Alix L, Didon A, Steichen O, Ranque B, Froissart A, Amadou K, Hanslik T, Cador B, Bergmann JF, Mekininan A, Goujard C, Gayet S, Cathebras P, Fantin B, Raigniac D, Weber JC, Rosenthal E, Hery L, Andres E, Benhamou Y, Bourgarit A, plgS2
[Characteristics of patients admitted from emergency units in 18 internal medicine departments and organisation of these departments: A cross sectional study from SNFMI (SiFMI study group) in 2015].
La Revue De Medecine Interne 2021, 42, 79-85.
Le Menestrel A, Guerin F, Chau F, Massias L, Benchetrit L, Cattoir V, Fantin B, de Lastours V
Activity of the combination of colistin and fosfomycin against NDM-1-producing Escherichia coli with variable levels of susceptibility to colistin and fosfomycin in a murine model of peritonitis.
The Journal of Antimicrobial Chemotherapy 2021, 77, 155-163.
2020
Canovas J, Petitjean G, Chau F, Le Monnier A, Fantin B, Lefort A
Expression of CTX-M-15 limits the efficacy of ceftolozane/tazobactam against Escherichia coli in a high-inoculum murine peritonitis model.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, 26, 1416.e5-1416.e9.
Nguyen Y, Corre F, Honsel V, Curac S, Zarrouk V, Fantin B, Galy A
Applicability of the CURB-65 pneumonia severity score for outpatient treatment of COVID-19.
The Journal of Infection 2020, 81, e96-e98.
Garrigues E, Janvier P, Kherabi Y, Le Bot A, Hamon A, Gouze H, Doucet L, Berkani S, Oliosi E, Mallart E, Corre F, Zarrouk V, Moyer JD, Galy A, Honsel V, Fantin B, Nguyen Y
Post-discharge persistent symptoms and health-related quality of life after hospitalization for COVID-19.
The Journal of Infection 2020, 81, e4-e6.
Lampros A, Montardi C, Journeau L, Georgin-Lavialle S, Hanslik T, Dhôte R, Goujard C, Le Jeunne C, Mahe I, Papo T, Godeau B, Bourgarit A, Fain O, Fantin B, Dzierzynski N, Leblanc J, Nevoret C, Steichen O
[Association between psychiatric comorbidities and hospital length of stay in post-emergency internal medicine patients].
La Revue De Medecine Interne 2020, 41, 360-367.
Nguyen Y, Corre F, Honsel V, Curac S, Zarrouk V, Burtz CP, Weiss E, Moyer JD, Gauss T, Grégory J, Bert F, Trichet C, Peoc'h K, Vilgrain V, Rebours V, Fantin B, Galy A
A nomogram to predict the risk of unfavourable outcome in COVID-19: a retrospective cohort of 279 hospitalized patients in Paris area.
Annals of Medicine 2020, 52, 367-375.
Pourbaix A, Zarrouk V, Allaham W, Leflon V, Rousseau MA, Goutagny S, Guigui P, Fantin B
More complications in cervical than in non-cervical spine tuberculosis.
Infectious Diseases (London, England) 2020, 52, 170-176.
Perrineau S, Zarrouk V, Zoghlami M, Allaham W, Leflon-Guibout V, Rousseau MA, Fantin B
Different kinetics of infectious processes in vertebral osteomyelitis of pyogenic or tuberculous origin explain different timing of surgery.
Infectious Diseases (London, England) 2020, 52, 563-570.
de Lastours V, Laouénan C, Royer G, Carbonnelle E, Lepeule R, Esposito-Farèse M, Clermont O, Duval X, Fantin B, Mentré F, Decousser JW, Denamur E, Lefort A
Mortality in Escherichia coli bloodstream infections: antibiotic resistance still does not make it.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2334-2343.
Cheminet G, de Lastours V, Poirel L, Chau F, Peoc'h K, Massias L, Fantin B, Nordmann P
Dimercaptosuccinic acid in combination with carbapenems against isogenic strains of Escherichia coli producing or not producing a metallo-β-lactamase in vitro and in murine peritonitis.
The Journal of Antimicrobial Chemotherapy 2020, 75, 3593-3600.
Lafont E, Roux O, de Lastours V, Dokmak S, Leflon V, Fantin B, Lefort A
Pyogenic liver abscess in liver transplant recipient: A warning signal for the risk of recurrence and retransplantation.
Transplant Infectious Disease: An Official Journal of the Transplantation Society 2020, 22, e13360.
Roujansky A, de Lastours V, Guérin F, Chau F, Cheminet G, Massias L, Cattoir V, Fantin B
Analysis of Paradoxical Efficacy of Carbapenems against Carbapenemase-Producing Escherichia coli in a Murine Model of Lethal Peritonitis.
Antimicrobial Agents and Chemotherapy 2020, 64,
Nguyen Y, Stirnemann J, Lautredoux F, Cador B, Bengherbia M, Yousfi K, Hamroun D, Astudillo L, Billette de Villemeur T, Brassier A, Camou F, Dalbies F, Dobbelaere D, Gaches F, Leguy-Seguin V, Masseau A, Pers YM, Pichard S, Serratrice C, Berger MG, Fantin B, Belmatoug N, On Behalf Of The French Evaluation Of Gaucher Disease Treatment Committee n
Immunoglobulin Abnormalities in Gaucher Disease: an Analysis of 278 Patients Included in the French Gaucher Disease Registry.
International Journal of Molecular Sciences 2020, 21,
Leo S, Lazarevic V, Girard M, Gaïa N, Schrenzel J, de Lastours V, Fantin B, Bonten M, Carmeli Y, Rondinaud E, Harbarth S, Huttner BD
Metagenomic Characterization of Gut Microbiota of Carriers of Extended-Spectrum Beta-Lactamase or Carbapenemase-Producing Enterobacteriaceae Following Treatment with Oral Antibiotics and Fecal Microbiota Transplantation: Results from a Multicenter Randomized Trial.
Microorganisms 2020
2019
Huttner BD, de Lastours V, Wassenberg M, Maharshak N, Mauris A, Galperine T, Zanichelli V, Kapel N, Bellanger A, Olearo F, Duval X, Armand-Lefevre L, Carmeli Y, Bonten M, Fantin B, Harbarth S, RGWsg
A 5-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae: a randomized clinical trial.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019, 25, 830-838.
Fantin B, Poujade J, Grégoire N, Chau F, Roujansky A, Kieffer N, Berleur M, Couet W, Nordmann P
The inoculum effect of Escherichia coli expressing mcr-1 or not on colistin activity in a murine model of peritonitis.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019, 25, 1563.e5-1563.e8.
Sokal A, Sauvanet A, Fantin B, de Lastours V
Acute cholangitis: Diagnosis and management.
Journal of Visceral Surgery 2019
Hoen B, Varon E, Debroucker T, Fantin B, Grimprel E, Wolff M, Duval X, earg
Management of acute community-acquired bacterial meningitis (excluding newborns). Short text.
Medecine Et Maladies Infectieuses 2019, 49, 367-404.
Hoen B, Varon E, de Debroucker T, Fantin B, Grimprel E, Wolff M, Duval X, earg
Management of acute community-acquired bacterial meningitis (excluding newborns). Long version with arguments.
Medecine Et Maladies Infectieuses 2019, 49, 405-441.
Gocko X, Lenormand C, Lemogne C, Bouiller K, Gehanno JF, Rabaud C, Perrot S, Eldin C, de Broucker T, Roblot F, Toubiana J, Sellal F, Vuillemet F, Sordet C, Fantin B, Lina G, Sobas C, Jaulhac B, Figoni J, Chirouze C, Hansmann Y, Hentgen V, Caumes E, Dieudonné M, Picone O, Bodaghi B, Gangneux JP, Degeilh B, Partouche H, Saunier A, Sotto A, Raffetin A, Monsuez JJ, Michel C, Boulanger N, Cathebras P, Tattevin P, ebtfss
Lyme borreliosis and other tick-borne diseases. Guidelines from the French scientific societies.
Medecine Et Maladies Infectieuses 2019, 49, 296-317.
Ruppé E, Ghozlane A, Tap J, Pons N, Alvarez AS, Maziers N, Cuesta T, Hernando-Amado S, Clares I, Martínez JL, Coque TM, Baquero F, Lanza VF, Máiz L, Goulenok T, de Lastours V, Amor N, Fantin B, Wieder I, Andremont A, van Schaik W, Rogers M, Zhang X, Willems RJL, de Brevern AG, Batto JM, Blottière HM, Léonard P, Léjard V, Letur A, Levenez F, Weiszer K, Haimet F, Doré J, Kennedy SP, Ehrlich SD
Prediction of the intestinal resistome by a three-dimensional structure-based method.
Nature Microbiology 2019, 4, 112-123.
Canouï E, Zarrouk V, Canouï-Poitrine F, Desmoulin U, Leflon V, Allaham W, de Lastours V, Guigui P, Fantin B
Surgery is safe and effective when indicated in the acute phase of hematogenous pyogenic vertebral osteomyelitis.
Infectious Diseases (London, England) 2019, 51, 268-276.
Alexandre K, Soares A, Chau F, Fantin B, Caron F, Etienne M
Temocillin breakpoints in pyelonephritis: evaluation in a murine model due to ESBL-producing Escherichia coli clinical isolates.
The Journal of Antimicrobial Chemotherapy 2019, 74, 1323-1326.
Pourbaix A, Guérin F, Burdet C, Massias L, Chau F, Cattoir V, Fantin B
Unexpected Activity of Oral Fosfomycin against Resistant Strains of Escherichia coli in Murine Pyelonephritis.
Antimicrobial Agents and Chemotherapy 2019, 63, e00903-19.
2018
de Lastours V, Goulenok T, Guérin F, Jacquier H, Eyma C, Chau F, Cattoir V, Fantin B
Ceftriaxone promotes the emergence of AmpC-overproducing Enterobacteriaceae in gut microbiota from hospitalized patients.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2018, 37, 417-421.
Alexandre K, Fantin B
Pharmacokinetics and Pharmacodynamics of Temocillin.
Clinical Pharmacokinetics 2018, 57, 287-296.
Froissart A, Rossi B, Ranque B, Jarrin I, Bergmann JF, Beaune S, Dautheville S, Breau N, Dauvergne A, Deluche L, Robert T, Gault N, Roy C, Zarrouk V, Steichen O, Fantin B
Effect of a Red Blood Cell Transfusion on Biological Markers Used to Determine the Cause of Anemia: A Prospective Study.
Am J Med 2018, 131, 319-322.
Kaddour K, Lemasson J, Haettich-Pialoux B, Guedj N, Belmatoug N, Treton X, Becheur H, Fantin B, Descamps V, Le Bozec P
[The value of fecal calprotectin assay in chronic panniculitis of unknown etiology].
Annales De Dermatologie Et De Venereologie 2018, 145, 702-705.
Jannic A, Maillet J, Rossi B, Guedj N, Descamps V, Fantin B, Le Bozec P
Flagellate erythema in systemic sclerosis: A case report.
JAAD case reports 2018, 4, 239-241.
Cheminet G, Kapel N, Bleibtreu A, Sadou-Yaye H, Bellanger A, Duval X, Joly F, Fantin B, de Lastours V, FGfFMT(
Faecal microbiota transplantation with frozen capsules for relapsing Clostridium difficile infections: the first experience from 15 consecutive patients in France.
The Journal of Hospital Infection 2018, 100, 148-151.
Goulenok T, Chopin D, De Lastours V, Zarrouk V, Lepeule R, Fantin B, Lefort A
[Influenzae and pneumococcal vaccination rate in an internal medicine ward].
La Revue De Medecine Interne 2018, 39, 386-392.
Zarrouk V, Gras J, Dubée V, de Lastours V, Lopes A, Leflon V, Allaham W, Guigui P, Fantin B
Increased mortality in patients aged 75 years or over with pyogenic vertebral osteomyelitis.
Infectious Diseases (London, England) 2018, 50, 783-787.
Berleur M, Guérin F, Massias L, Chau F, Poujade J, Cattoir V, Fantin B, de Lastours V
Activity of fosfomycin alone or combined with temocillin in vitro and in a murine model of peritonitis due to KPC-3- or OXA-48-producing Escherichia coli.
The Journal of Antimicrobial Chemotherapy 2018, 73, 3074-3080.
Rossi B, Gasperini ML, Leflon-Guibout V, Gioanni A, de Lastours V, Rossi G, Dokmak S, Ronot M, Roux O, Nicolas-Chanoine MH, Fantin B, Lefort A
Hypervirulent Klebsiella pneumoniae in Cryptogenic Liver Abscesses, Paris, France.
Emerging Infectious Diseases 2018, 24, 221-229.
2017
Stahl JP, Azouvi P, Bruneel F, De Broucker T, Duval X, Fantin B, Girard N, Herrmann JL, Honnorat J, Lecuit M, Mailles A, Martinez-Almoyna L, Morand P, Piroth L, Tattevin P, rg
Guidelines on the management of infectious encephalitis in adults.
Medecine Et Maladies Infectieuses 2017, 47, 179-194.
Goulenok T, Buzelé R, Duval X, Bruneel F, Stahl JP, Fantin B
Management of adult infectious encephalitis in metropolitan France.
Medecine Et Maladies Infectieuses 2017, 47, 206-220.
Perrineau S, Cazals-Hatem D, Zarrouk V, Fantin B, de Lastours V
Cytomegalovirus-associated protein-losing enteropathy in a healthy man.
Medecine Et Maladies Infectieuses 2017, 47, 562-565.
de Lastours V, Maugy E, Mathy V, Chau F, Rossi B, Guérin F, Cattoir V, Fantin B, CSG
Ecological impact of ciprofloxacin on commensal enterococci in healthy volunteers.
The Journal of Antimicrobial Chemotherapy 2017, 72, 1574-1580.
Nguyen Y, Rossi B, Argy N, Baker C, Nickel B, Marti H, Zarrouk V, Houzé S, Fantin B, Lefort A
Autochthonous Case of Eosinophilic Meningitis Caused by Angiostrongylus cantonensis, France, 2016.
Emerging Infectious Diseases 2017, 23, 1045-1046.
2016
Buzelé R, Barbier L, Sauvanet A, Fantin B
Medical complications following splenectomy.
Journal of Visceral Surgery 2016, 153, 277-286.
de Lastours V, Fantin B
[Pyogenic brain abscesses in adults].
La Revue De Medecine Interne / Fondee ... Par La Societe Nationale Francaise De Medecine Interne 2016
Rossi G, Lafont E, Gasperini L, Dokmak S, Ronot M, Rossi B, Zarrouk V, Fantin B, Lefort A
[Liver abscess].
La Revue De Medecine Interne 2016, 37, 827-833.
Jayol A, Janvier F, Guillard T, Chau F, Mérens A, Robert J, Fantin B, Berçot B, Cambau E
qnrA6 genetic environment and quinolone resistance conferred on Proteus mirabilis.
The Journal of Antimicrobial Chemotherapy 2016, 71, 903-908.
Alexandre K, Chau F, Guérin F, Massias L, Lefort A, Cattoir V, Fantin B
Activity of temocillin in a lethal murine model of infection of intra-abdominal origin due to KPC-producing Escherichia coli.
The Journal of Antimicrobial Chemotherapy 2016
Audemard-Verger A, Descloux E, Ponard D, Deroux A, Fantin B, Fieschi C, John M, Bouldouyre A, Karkowsi L, Moulis G, Auvinet H, Valla F, Lechiche C, Davido B, Martinot M, Biron C, Lucht F, Asseray N, Froissart A, Buzelé R, Perlat A, Boutboul D, Fremeaux-Bacchi V, Isnard S, Bienvenu B
Infections Revealing Complement Deficiency in Adults: A French Nationwide Study Enrolling 41 Patients.
Medicine 2016, 95, e3548.
de Lastours V, Chopin D, Jacquier H, d'Humieres C, Burdet C, Chau F, Denamur E, Fantin B
Prospective Cohort Study of the Relative Abundance of Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli in the Gut of Patients Admitted to Hospitals.
Antimicrob Agents Chemother 2016, 60, 6941-6944.
Birgand G, Leroy C, Nerome S, Luong Nguyen LB, Lolom I, Armand-Lefevre L, Ciotti C, Lecorre B, Marcade G, Fihman V, Nicolas-Chanoine MH, Pelat C, Perozziello A, Fantin B, Yazdanpanah Y, Ricard JD, Lucet JC
Costs associated with implementation of a strict policy for controlling spread of highly resistant microorganisms in France.
BMJ open 2016, 6, e009029.
Galy A, Lepeule R, Goulenok T, Buzele R, de Lastours V, Fantin B
Presentation and impact of catheter-associated thrombosis in patients with infected long-term central venous catheters: a prospective bicentric observational study.
Annals of Medicine 2016, 48, 182-189.
2015
Buzelé R, Zarrouk V, Francoz C, Durand F, Fantin B
Characteristics of vertebral osteomyelitis after liver transplantation.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015
Munier AL, de Lastours V, Barbier F, Chau F, Fantin B, Ruimy R
Comparative dynamics of the emergence of fluoroquinolone resistance in staphylococci from the nasal microbiota of patients treated with fluoroquinolones according to their environment.
International Journal of Antimicrobial Agents 2015
Monnier D, Goulenok T, Allary J, Zarrouk V, Fantin B
[Starvation ketosis in a breastfeeding woman].
La Revue De Medecine Interne / Fondee ... Par La Societe Nationale Francaise De Medecine Interne 2015
Soubirou JF, Rossi B, Couffignal C, Ruppé E, Chau F, Massias L, Lepeule R, Mentre F, Fantin B
Activity of temocillin in a murine model of urinary tract infection due to Escherichia coli producing or not producing the ESBL CTX-M-15.
The Journal of Antimicrobial Chemotherapy 2015, 70, 1466–1472.
Rossi B, Soubirou J, Chau F, Massias L, Dion S, Lepeule R, Fantin B, Lefort A
Cefotaxime and Amoxicillin-Clavulanate Synergism against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Urinary Tract Infection.
Antimicrobial Agents and Chemotherapy 2015, 32, 1708.
de Lastours V, Fantin B
Impact of fluoroquinolones on human microbiota. Focus on the emergence of antibiotic resistance.
Future Microbiology 2015, 10, 1241-1255.
2014
Lefort A, Chau F, Lepeule R, Dubée V, Kitzis MD, Dion S, Fantin B
Activity of fosfomycin alone or combined with cefoxitin in vitro and in vivo in a murine model of urinary tract infection due to Escherichia coli harbouring CTX-M-15-type extended-spectrum β-lactamase.
International Journal of Antimicrobial Agents 2014, 43, 366-369.
Pierre I, Zarrouk V, Noussair L, Molina JM, Fantin B
Invasive actinomycosis: surrogate marker of a poor prognosis in immunocompromised patients.
International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 2014, 29, 74-79.
Lemaignen A, Goulenok T, Kalamarides S, Plat A, Pfau G, Fantin B
[Agranulocytosis and vasculitis in a cocaine addict: Levamisole, the hidden culprit].
La Revue De Médecine Interne / Fondée ... Par La Société Nationale Francaise De Médecine Interne 2014, 35, 676-679.
de Lastours V, Fantin B
[Resistance to fluoroquinolones in 2013: what are the consequences in internal medicine?].
La Revue De Médecine Interne / Fondée ... Par La Société Nationale Francaise De Médecine Interne 2014, 35, 601-608.
Fillion A, Koutlidis N, Froissart A, Fantin B
[Investigation and management of genito-urinary tuberculosis.].
La Revue De Medecine Interne / Fondee ... Par La Societe Nationale Francaise De Medecine Interne 2014
Roubaud Baudron C, Panhard X, Clermont O, Mentré F, Fantin B, Denamur E, Lefort A, CG
Escherichia coli bacteraemia in adults: age-related differences in clinical and bacteriological characteristics, and outcome.
Epidemiology and Infection 2014, 142, 2672-2683.
de Lastours V, Bleibtreu A, Chau F, Burdet C, Duval X, Denamur E, Fantin B
Quinolone-resistant Escherichia coli from the faecal microbiota of healthy volunteers after ciprofloxacin exposure are highly adapted to a commensal lifestyle.
The Journal of Antimicrobial Chemotherapy 2014, 69, 761-768.
de Lastours V, Chau F, Roy C, Larroque B, Fantin B
Emergence of quinolone resistance in the microbiota of hospitalized patients treated or not with a fluoroquinolone.
The Journal of Antimicrobial Chemotherapy 2014
Vigan M, Stirnemann J, Caillaud C, Froissart R, Boutten A, Fantin B, Belmatoug N, Mentré F
Modeling changes in biomarkers in Gaucher disease patients receiving enzyme replacement therapy using a pathophysiological model.
Orphanet Journal of Rare Diseases 2014, 9, 95.
Desbois A, Rautou P, Biard L, Belmatoug N, Wechsler B, Resche-Rigon M, Zarrouk V, Fantin B, Pineton de Chambrun M, Cacoub P, Valla D, Saadoun D, Plessier A
Behcet¿s disease in Budd-Chiari syndrome.
Orphanet Journal of Rare Diseases 2014, 9, 104.
Dubée V, Zeller V, Fantin B
[Infections associated with orthopaedic devices].
La Revue Du Praticien 2014, 64, 643-650.
2013
Goulenok T, Fantin B
Antimicrobial treatment of febrile neutropenia: pharmacokinetic-pharmacodynamic considerations.
Clinical Pharmacokinetics 2013, 52, 869-883.
Guillard T, Cambau E, Chau F, Massias L, de Champs C, Fantin B
Ciprofloxacin treatment failure in a murine model of pyelonephritis due to an AAC(6')-Ib-cr-producing Escherichia coli strain susceptible to ciprofloxacin in vitro.
Antimicrobial Agents and Chemotherapy 2013, 57, 5830-5835.
Cornely OA, Miller MA, Fantin B, Mullane K, Kean Y, Gorbach S
Resolution of Clostridium difficile-associated diarrhea in patients with cancer treated with fidaxomicin or vancomycin.
Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology 2013, 31, 2493-2499.
2012
Ruppe E, Pitsch A, Tubach F, de Lastours V, Chau F, Pasquet B, Lucet JC, Andremont A, Fantin B
Clinical predictive values of extended-spectrum beta-lactamase carriage in patients admitted to medical wards.
European Journal of Clinical Microbiology & Infectious Diseases 2012, 31, 319-325.
Mekinian A, Stirnemann J, Belmatoug N, Heraoui D, Fantin B, Fain O, Charpentier A, Rose C
Ferritinemia during type 1 Gaucher disease: mechanisms and progression under treatment.
Blood Cells, Molecules & Diseases 2012, 49, 53-57.
Lebeaux D, Zarrouk V, Petrover D, Nicolas-Chanoine MH, Fantin B
Salmonella Colindale osteomyelitis in an immunocompetent female patient.
Medecine Et Maladies Infectieuses 2012, 42, 36-37.
Froissart A, Gazaignes S, Gellen-Dautremer J, Leflon-Guibout V, Iakovlev G, Zarrouk V, Lefort A, Fantin B
[Intermittent prolonged fever triggered by efforts].
La Revue De Médecine Interne / Fondée ... Par La Société Nationale Francaise De Médecine Interne 2012, 33, 519-521.
Dubée V, Lenoir T, Leflon-Guibout V, Briere-Bellier C, Guigui P, Fantin B
Three-month antibiotic therapy for early-onset postoperative spinal implant infections.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012, 55, 1481-1487.
Lebeaux D, Larroque B, Gellen-Dautremer J, Leflon-Guibout V, Dreyer C, Bialek S, Froissart A, Hentic O, Tessier C, Ruimy R, Pelletier AL, Crestani B, Fournier M, Papo T, Barry B, Zarrouk V, Fantin B
Clinical outcome after a totally implantable venous access port-related infection in cancer patients: a prospective study and review of the literature.
Medicine 2012, 91, 309-318.
Lepeule R, Ruppé E, Le P, Massias L, Chau F, Nucci A, Lefort A, Fantin B
Cefoxitin as an alternative to carbapenems in a murine model of urinary tract infection due to Escherichia coli harboring CTX-M-15-type extended-spectrum β-lactamase.
Antimicrobial Agents and Chemotherapy 2012, 56, 1376-1381.
Stirnemann J, Vigan M, Hamroun D, Heraoui D, Rossi-Semerano L, Berger MG, Rose C, Camou F, de Roux-Serratrice C, Grosbois B, Kaminsky P, Robert A, Caillaud C, Froissart R, Levade T, Masseau A, Mignot C, Sedel F, Dobbelaere D, Vanier MT, Valayanopoulos V, Fain O, Fantin B, de Villemeur TB, Mentré F, Belmatoug N
The French Gaucher's disease registry: clinical characteristics, complications and treatment of 562 patients.
Orphanet Journal of Rare Diseases 2012, 7, 77.
2011
Stirnemann J, Boutten A, Vincent C, Mekinian A, Heraoui D, Fantin B, Fain O, Mentré F, Belmatoug N
Impact of imiglucerase on the serum glycosylated-ferritin level in Gaucher disease.
Blood Cells, Molecules & Diseases 2011, 46, 34-38.
Lucet JC, Nicolas-Chanoine MH, Lefort A, Roy C, Diamantis S, Papy E, Riveros-Palacios O, Le Grand J, Rioux C, Fantin B, Ravaud P
Do case vignettes accurately reflect antibiotic prescription?.
Infection Control and Hospital Epidemiology 2011, 32, 1003-1009.
Lucet JC, Nicolas-Chanoine MH, Roy C, Riveros-Palacios O, Diamantis S, Le Grand J, Papy E, Rioux C, Fantin B, Lefort A, Ravaud P
Antibiotic use: knowledge and perceptions in two university hospitals.
The Journal of Antimicrobial Chemotherapy 2011, 66, 936-940.
Courpon-Claudinon A, Lefort A, Panhard X, Clermont O, Dornic Q, Fantin B, Mentré F, Wolff M, Denamur E, Branger C, CG
Bacteraemia caused by third-generation cephalosporin-resistant Escherichia coli in France: prevalence, molecular epidemiology and clinical features.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2011, 17, 557-565.
Lefort A, Panhard X, Clermont O, Woerther PL, Branger C, Mentré F, Fantin B, Wolff M, Denamur E, CG
Host factors and portal of entry outweigh bacterial determinants to predict the severity of Escherichia coli bacteremia.
Journal of Clinical Microbiology 2011, 49, 777-783.
2010
Zarrouk V, Leflon-Guibout V, Robineaux S, Kalamarides M, Nicolas-Chanoine MH, Sterkers O, Fantin B
Broad-range 16S rRNA PCR with cerebrospinal fluid may be unreliable for management of postoperative aseptic meningitis.
Journal of Clinical Microbiology 2010, 48, 3331-3333.
Stirnemann J, Belmatoug N, Vincent C, Fain O, Fantin B, Mentré F
Bone events and evolution of biologic markers in Gaucher disease before and during treatment.
Arthritis Research & Therapy 2010, 12, R156.
2009
Fantin B, Duval X, Massias L, Alavoine L, Chau F, Retout S, Andremont A, Mentré F
Ciprofloxacin dosage and emergence of resistance in human commensal bacteria.
The Journal of Infectious Diseases 2009, 200, 390-398.
Allou N, Cambau E, Massias L, Chau F, Fantin B
Impact of low-level resistance to fluoroquinolones due to qnrA1 and qnrS1 genes or a gyrA mutation on ciprofloxacin bactericidal activity in a murine model of Escherichia coli urinary tract infection.
Antimicrobial Agents and Chemotherapy 2009, 53, 4292-4297.
2008
Bellier C, Bert F, Durand F, Retout S, Belghiti J, Mentré F, Fantin B
Risk factors for Enterobacteriaceae bacteremia after liver transplantation.
Transplant International: Official Journal of the European Society for Organ Transplantation 2008, 21, 755-763.
Rouzet F, Dominguez Hernandez M, Hervatin F, Sarda-Mantel L, Lefort A, Duval X, Louedec L, Fantin B, Le Guludec D, Michel JB
Technetium 99m-labeled annexin V scintigraphy of platelet activation in vegetations of experimental endocarditis.
Circulation 2008, 117, 781-789.
de Lastours V, Kalamarides M, Leflon V, Rodallec M, Vilgrain V, Nicolas-Chanoine MH, Fantin B
Optimization of bacterial diagnosis yield after needle aspiration in immunocompetent adults with brain abscesses.
Neurosurgery 2008, 63, 362-367; discussion 367-368.
2005
Bert F, Bellier C, Lassel L, Lefranc V, Durand F, Belghiti J, Mentré F, Fantin B
Risk factors for Staphylococcus aureus infection in liver transplant recipients.
Liver Transplantation: Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2005, 11, 1093-1099.
Labat F, Pradillon O, Garry L, Peuchmaur M, Fantin B, Denamur E
Mutator phenotype confers advantage in Escherichia coli chronic urinary tract infection pathogenesis.
FEMS immunology and medical microbiology 2005, 44, 317-321.
2004
Lefort A, Arthur M, Depardieu F, Chau F, Pouzet C, Courvalin P, Fantin B
Expression of glycopeptide-resistance gene in response to vancomycin and teicoplanin in the cardiac vegetations of rabbits infected with VanB-type Enterococcus faecalis.
The Journal of Infectious Diseases 2004, 189, 90-97.
2000
Bert F, Galdbart JO, Zarrouk V, Le Mee J, Durand F, Mentre F, Belghiti J, Lambert-Zechovsky N, Fantin B
Association between nasal carriage of Staphylococcus aureus and infection in liver transplant recipients.
Clinical Infectious Diseases 2000, 31, 1295-1299.
1989
Leggett JE, Fantin B, Ebert S, Totsuka K, Vogelman B, Calame W, Mattie H, Craig WA
Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection models.
The Journal of Infectious Diseases 1989, 159, 281-292.