First name: Etienne
  Last name: Carbonnelle
  Function: Enseignant chercheur
  Position: PU-PH
  Email: etienne.carbonnelle

Research interest



2013: Research Director degree (HDR), Paris Descartes University,
2005: Ph. D. in Microbiology, Paris Descartes University,
2001: Medical Doctor in Clinical Biology, Paris Pierre and Marie Curie University,
2001: Speciality in Medical Biology,
2000: Master of Science in Microbiology, Paris,
1999: Inter University degree, “Molecular biology of the cell”, Paris Diderot University,
1989-1995: First and second cycle of Medical studies, University Angers, France.

Academic positions

2016-present: Medical director of Biology laboratory, Avicenne and Jean-Verdier hospitals,
2014-present: Head of the Microbiology laboratory, Avicenne and Jean-Verdier hospitals,
2008-2014: Associate Professor in Bacteriology, Medical school, Paris Descartes University,
2007-2008: Poste d’accueil APHP-CNRS, UMR8619, Paris-Sud University,
2005-2007: Assistant professor in Microbiology, Medical school, Paris Descartes University,
2002-2004: Poste d’accueil INSERM, U570,
1995-2001: Resident, Paris Pierre and Marie Curie University.

Research training (post doctoral)

2014-present: Researcher at the INSERM unit UMR 1137, IAME team EVRest, Paris Nord University and Paris Diderot University, director Pr. E. Denamur,
2008-2014: Researcher at the INSERM unit UMR 872, Paris Descartes University, director Dr. M. Arthur,
2007-2008: Researcher at the CNRS unit UMR8619, Paris-Sud University, director Dr. D. Menguin-Lecreulx
1999-2007: Researcher at the INSERM unit 411 then 570, Paris Descartes University, Paris, director Pr. X. Nassif

Exhaustive list of publications


Hassold N, Brichler S, Gater Y, Leclerc D, Gordien E, Bouchaud O, Carbonnelle E, Mechai F, Cordel H, Delagreverie H
Mixed outcomes following a third SARS-CoV-2 vaccine dose in previously unresponsive people with HIV.
Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology 2023, 158, 105347.


Kolakowska A, El Alaoui F, Ben Alba H, Challal S, Carbonnelle E, Jaureguy F
Vaginal microbiota as an unusual cause of spondylodiscitis.
Archives of Gynecology and Obstetrics 2022, 306, 109-114.

Méchaï F, Bachelet D, Han L, Dubert M, Parisey M, Cordel H, Bourgarit A, Bertrac C, Chauveau S, Billard-Pomares T, Carbonnelle E, Bouchaud O, Yazdanpanah Y, Vignier N, Laouénan C
Tuberculosis treatment outcomes among precarious patients in France.
Infectious Diseases Now 2022, 52, 389-395.

Magréault S, Jaureguy F, Zahar JR, Méchaï F, Toinon D, Cohen Y, Carbonnelle E, Jullien V
Automated HPLC-MS/MS assay for the simultaneous determination of ten plasma antibiotic concentrations.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2022, 1211, 123496.

Nagle S, Tandjaoui-Lambiotte Y, Boubaya M, Athenaïs G, Alloui C, Bloch-Queyrat C, Carbonnelle E, Brichler S, Cohen Y, Zahar JR, Delagrèverie H
Environmental SARS-CoV-2 contamination in hospital rooms of patients with acute COVID-19.
The Journal of Hospital Infection 2022, 126, 116-122.

Hassold N, Brichler S, Ouedraogo E, Leclerc D, Carroue S, Gater Y, Alloui C, Carbonnelle E, Bouchaud O, Mechai F, Cordel H, Delagreverie H
Impaired antibody response to COVID-19 vaccination in advanced HIV infection.
AIDS (London, England) 2022, 36, F1-F5.

Magréault S, Jauréguy F, Carbonnelle E, Zahar JR
When and How to Use MIC in Clinical Practice?.
Antibiotics (Basel, Switzerland) 2022, 11, 1748.

Billard-Pomares T, Marin J, Quagliaro P, Méchaï F, Walewski V, Dziri S, Carbonnelle E
Use of Whole-Genome Sequencing to Explore Mycobacterium tuberculosis Complex Circulating in a Hotspot Department in France.
Microorganisms 2022, 10, 1586.


Saliba R, Ghelfenstein-Ferreira T, Lomont A, Pilmis B, Carbonnelle E, Seytre D, Nasser-Ayoub E, Zahar JR, Karam-Sarkis D
Risk factors for the environmental spread of different multidrug-resistant organisms: a prospective cohort study.
The Journal of Hospital Infection 2021, 111, 155-161.

Grall I, Alloui CA, Tandjaoui-Lambiotte Y, Deslandes A, Seytre D, Chappe J, Carbonnelle E, Brichler S, Jacolot A, Zahar JR, Lomont A
Viral transmission in asymptomatic cases of SARS-CoV-2 infection.
The Journal of Infection 2021, 82, 282-327.

Gressens SB, Billard-Pomares T, Leboité H, Cruaud P, Bouchaud O, Carbonnelle E, Méchaï F
Pulmonary tuberculosis: Evaluation of current diagnostic strategy.
Infectious Diseases Now 2021, 51, 273-278.

Ghelfenstein-Ferreira T, Beaumont AL, Dellière S, Peiffer-Smadja N, Pineros N, Carbonnelle E, Greub G, Abbara S, Luong Nguyen LB, Lescat M
An Educational Game Evening for Medical Residents: A Proof of Concept to Evaluate the Impact on Learning of the Use of Games.
Journal of Microbiology & Biology Education 2021, 22, e00119-21.


Madelain V, Duthey A, Mentré F, Jacquot F, Solas C, Lacarelle B, Vallvé A, Barron S, Barrot L, Mundweiler S, Thomas D, Carbonnelle C, Raoul H, de Lamballerie X, Guedj J
Ribavirin does not potentiate favipiravir antiviral activity against Ebola virus in non-human primates.
Antiviral Research 2020, 177, 104758.

Saliba R, Zahar JR, El Allaoui F, Carbonnelle E, Lescat M
Impact of freeze/thaw cycles and single freezing at -80 °C on the viability of aerobic bacteria from rectal swabs performed with the ESwabTM system.
Diagnostic Microbiology and Infectious Disease 2020, 96, 114895.

Mizrahi A, Delerue T, Morel H, Le Monnier A, Carbonnelle E, Pilmis B, Zahar JR, obtSJSG
Infections caused by naturally AmpC-producing Enterobacteriaceae: Can we use third-generation cephalosporins? A narrative review.
International Journal of Antimicrobial Agents 2020, 55, 105834.

Deslandes A, Berti V, Tandjaoui-Lambotte Y, Alloui C, Carbonnelle E, Zahar JR, Brichler S, Cohen Y
SARS-CoV-2 was already spreading in France in late December 2019.
International Journal of Antimicrobial Agents 2020, 55, 106006.

Pilmis B, Billard-Pomares T, Martin M, Clarempuy C, Lemezo C, Saint-Marc C, Bourlon N, Seytre D, Carbonnelle E, Zahar JR
Can environmental contamination be explained by particular traits associated with patients?.
The Journal of Hospital Infection 2020, 104, 293-297.

de Lastours V, Laouénan C, Royer G, Carbonnelle E, Lepeule R, Esposito-Farèse M, Clermont O, Duval X, Fantin B, Mentré F, Decousser JW, Denamur E, Lefort A
Mortality in Escherichia coli bloodstream infections: antibiotic resistance still does not make it.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2334-2343.

Lomont A, Boubaya M, Khamis W, Deslandes A, Cordel H, Seytre D, Alloui C, Malaure C, Bonnet N, Carbonnelle E, Cohen Y, Nunes H, Bouchaud O, Zahar JR, Tandjaoui-Lambiotte Y
Environmental contamination related to SARS-CoV-2 in ICU patients.
ERJ open research 2020


Delerue T, Cordel H, Delerue T, Figoni J, Dziri S, Billard-Pomares T, Bouchaud O, Carbonnelle E, Zahar JR
Prediction of methicillin-resistant Staphylococcus aureus bloodstream infection: do we need rapid diagnostic tests?.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2019, 38, 1319-1326.

Carrie C, Walewski V, Levy C, Alexandre C, Baleine J, Charreton C, Coche-Monier B, Caeymaex L, Lageix F, Lorrot M, Klosowski S, Hess L, Zafer O, Gaudelus J, Pinquier D, Carbonnelle E, Cohen R, de Pontual L
Klebsiella pneumoniae and Klebsiella oxytoca meningitis in infants. Epidemiological and clinical features.
Archives De Pediatrie: Organe Officiel De La Societe Francaise De Pediatrie 2019, 26, 12-15.

Saliba R, Neulier C, Seytre D, Fiacre A, Faibis F, Leduc P, Amara M, Jauréguy F, Carbonnelle E, Zahar JR, Marty L
Can real-time polymerase chain reaction allow a faster recovery of hospital activity in cases of an incidental discovery of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant Enterococci carriers?.
Journal of Hospital Infection 2019, 103, 115-120.

Billard-Pomares T, Bleibtreu A, Walewski V, Dziri S, Barbat A, Zahar JR, Cruaud P, Carbonnelle E
Proposition of a safe Mycobacterium tuberculosis complex denaturation method that does not compromise the integrity of DNA for whole-genome sequencing.
Tuberculosis 2019, 117, 62-64.

Pouletty M, De Pontual L, Lopez M, Morin L, Poilane I, Pham LL, Carbonnelle E, Titomanlio L, Faye A, Bonacorsi S
Multiplex PCR reveals a high prevalence of multiple pathogens in traveller's diarrhoea in children.
Archives of Disease in Childhood 2019, 104, 141-146.


Macaux L, Ndoye O, Cordel H, Pomares TB, Seytre D, Bouchaud O, Cohen Y, Zahar JR, Carbonnelle E
Extensively-drug-resistant bacteria carriers among overseas travellers: one-third had not been hospitalized previously.
International Journal of Antimicrobial Agents 2018, 52, 385-389.

Jauréguy F, Mansour H, Bigot J, Walewski V, Billard-Pomares T, Rahajamanana L, Picard B, Carbonnelle E
Use of the Xpert CarbaR assay for direct detection of carbapenemase genes from blood cultures and urine samples.
The Journal of Hospital Infection 2018, 98, 245-246.

Garinet S, Fihman V, Jacquier H, Corvec S, Le Monnier A, Guillard T, Cattoir V, Zahar JR, Woerther PL, Carbonnelle E, Wargnier A, Kernéis S, Morand PC, G
Elective distribution of resistance to beta-lactams among Enterobacter cloacae genetic clusters.
The Journal of Infection 2018, 77, 178-182.

Madelain V, Baize S, Jacquot F, Reynard S, Fizet A, Barron S, Solas C, Lacarelle B, Carbonnelle C, Mentré F, Raoul H, de Lamballerie X, Guedj J
Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies.
Nature Communications 2018, 9, 4013.

Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen THT, Rodallec A, Gunther S, Carbonnelle C, Mentre F, Raoul H, de Lamballerie X
Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques.
PLoS Med 2018, 15, e1002535.


Piorkowski G, Jacquot F, Quérat G, Carbonnelle C, Pannetier D, Mentré F, Raoul H, de Lamballerie X
Implementation of a non-human primate model of Ebola disease: Infection of Mauritian cynomolgus macaques and analysis of virus populations.
Antiviral Research 2017, 140, 95-105.

Billard-Pomares T, Rouyer C, Walewski V, Badell-Ocando E, Dumas M, Zumelzu C, Jaureguy F, Brisse S, Caux F, Bouchaud O, Carbonnelle E
Diagnosis in France of a Non-Toxigenic tox Gene-Bearing Strain of Corynebacterium diphtheriae in a Young Male Back From Senegal.
Open Forum Infectious Diseases 2017, 4, ofw271.

Delerue T, de Pontual L, Carbonnelle E, Zahar JR
The potential role of microbiota for controlling the spread of extended-spectrum beta-lactamase-producing Enterobacteriaceae (ESBL-PE) in neonatal population.
F1000Research 2017, 6, 1217.

Nguyen TH, Guedj J, Anglaret X, Laouenan C, Madelain V, Taburet AM, Baize S, Sissoko D, Pastorino B, Rodallec A, Piorkowski G, Carazo S, Conde MN, Gala JL, Bore JA, Carbonnelle C, Jacquot F, Raoul H, Malvy D, de Lamballerie X, Mentre F
Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted.
PLoS Negl Trop Dis 2017, 11, e0005389.


Verriere B, Sabatier B, Carbonnelle E, Mainardi JL, Prognon P, Whitaker I, Lantieri L, Hivelin M
Medicinal leech therapy and Aeromonas spp. infection.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2016, 35, 1001-1006.

Briand C, Levy C, Baumie F, Joao L, Béchet S, Carbonnelle E, Grimprel E, Cohen R, Gaudelus J, de Pontual L
Outcomes of bacterial meningitis in children.
Médecine Et Maladies Infectieuses 2016, 46, 177-187.

Walewski V, Méchaï F, Billard-Pomares T, Juguet W, Jauréguy F, Picard B, Tandjaoui-Lambiotte Y, Carbonnelle E, Bouchaud O
MALDI-TOF MS contribution to diagnosis of melioidosis in a nonendemic country in three French travellers.
New Microbes and New Infections 2016, 12, 31-34.

Sissoko D, Laouenan C, Folkesson E, M'Lebing AB, Beavogui AH, Baize S, Camara AM, Maes P, Shepherd S, Danel C, Carazo S, Conde MN, Gala JL, Colin G, Savini H, Bore JA, Le Marcis F, Koundouno FR, Petitjean F, Lamah MC, Diederich S, Tounkara A, Poelart G, Berbain E, Dindart JM, Duraffour S, Lefevre A, Leno T, Peyrouset O, Irenge L, Bangoura N, Palich R, Hinzmann J, Kraus A, Barry TS, Berette S, Bongono A, Camara MS, Chanfreau Munoz V, Doumbouya L, Souley Harouna n, Kighoma PM, Koundouno FR, Réné Lolamou n, Loua CM, Massala V, Moumouni K, Provost C, Samake N, Sekou C, Soumah A, Arnould I, Komano MS, Gustin L, Berutto C, Camara D, Camara FS, Colpaert J, Delamou L, Jansson L, Kourouma E, Loua M, Malme K, Manfrin E, Maomou A, Milinouno A, Ombelet S, Sidiboun AY, Verreckt I, Yombouno P, Bocquin A, Carbonnelle C, Carmoi T, Frange P, Mely S, Nguyen VK, Pannetier D, Taburet AM, Treluyer JM, Kolie J, Moh R, Gonzalez MC, Kuisma E, Liedigk B, Ngabo D, Rudolf M, Thom R, Kerber R, Gabriel M, Di Caro A, Wölfel R, Badir J, Bentahir M, Deccache Y, Dumont C, Durant JF, El Bakkouri K, Gasasira Uwamahoro M, Smits B, Toufik N, Van Cauwenberghe S, Ezzedine K, D'Ortenzio E, Dortenzio E, Pizarro L, Etienne A, Guedj J, Fizet A, Barte de Sainte Fare E, Murgue B, Tran-Minh T, Rapp C, Piguet P, Poncin M, Draguez B, Allaford Duverger T, Barbe S, Baret G, Defourny I, Carroll M, Raoul H, Augier A, Eholie SP, Yazdanpanah Y, Levy-Marchal C, Antierrens A, Van Herp M, Günther S, de Lamballerie X, Keïta S, Mentre F, Anglaret X, Malvy D, JSG
Experimental Treatment with Favipiravir for Ebola Virus Disease (the JIKI Trial): A Historically Controlled, Single-Arm Proof-of-Concept Trial in Guinea.
PLoS medicine 2016, 13, e1001967.

Hugonnet JE, Mengin-Lecreulx D, Monton A, den Blaauwen T, Carbonnelle E, Veckerlé C, Brun YV, van Nieuwenhze M, Bouchier C, Tu K, Rice LB, Arthur M
Factors essential for L,D-transpeptidase-mediated peptidoglycan cross-linking and β-lactam resistance in Escherichia coli.
eLife 2016


Walewski V, Podglajen I, Lefeuvre P, Dutasta F, Neuschwander A, Tilouche L, Carbonnelle E, Ferroni A
Early detection with the β-LACTA™ test of extended-spectrum β-lactamase-producing Enterobacteriaceae in blood cultures.
Diagnostic Microbiology and Infectious Disease 2015, 83, 216-218.

Ficko C, Bechara C, Gerin M, Carbonnelle E, Podglajen I, Mainardi JL
[Bloodstream infection due to Campylobacter fetus subspecies fetus and skin involvement: A case series of three patients].
La Revue De Medecine Interne / Fondee ... Par La Societe Nationale Francaise De Medecine Interne 2015

Kernéis S, Valade S, Geri G, Compain F, Lavollay M, Rostane H, Carbonnelle E, Mainardi JL
Cefoxitin as a carbapenem-sparing antibiotic for infections caused by extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae.
Infectious Diseases (London, England) 2015, 47, 793-799.


Shoai Tehrani M, Hajage D, Fihman V, Tankovic J, Cau S, Day N, Visseaux C, Carbonnelle E, Kouatchet A, Cattoir V, Nhan TX, Corvec S, Jacquier H, Jauréguy F, Le Monnier A, Morand P, Zahar JR, obtGdmc
Gram-negative bacteremia: which empirical antibiotic therapy?.
Médecine Et Maladies Infectieuses 2014, 44, 159-166.

Grohs P, Kernéis S, Sabatier B, Lavollay M, Carbonnelle E, Rostane H, Souty C, Meyer G, Gutmann L, Mainardi JL
Fighting the spread of AmpC-hyperproducing Enterobacteriaceae: beneficial effect of replacing ceftriaxone with cefotaxime.
The Journal of Antimicrobial Chemotherapy 2014, 69, 786-789.

Compain F, Decré D, Frazier I, Ramahefasolo A, Lavollay M, Carbonnelle E, Rostane H, Tackin A, Berger-Carbonne A, Podglajen I
Carbapenemase-producing bacteria in patients hospitalized abroad, France.
Emerging Infectious Diseases 2014, 20, 1246-1248.


Landraud L, Jauréguy F, Frapy E, Guigon G, Gouriou S, Carbonnelle E, Clermont O, Denamur E, Picard B, Lemichez E, Brisse S, Nassif X
Severity of Escherichia coli bacteraemia is independent of the intrinsic virulence of the strains assessed in a mouse model.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2013, 19, 85-90.


Guillet M, Zahar JR, Timsit MO, Grandin L, Carbonnelle E, Join-Lambert O, Quesne G, Nassif X, Mejean A, Carbonne A
Horizontal transmission of Streptococcus pneumoniae in the surgical ward: a rare source of nosocomial wound infection.
American Journal of Infection Control 2012, 40, 71-72.

Fihman V, Le Monnier A, Corvec S, Jaureguy F, Tankovic J, Jacquier H, Carbonnelle E, Bille E, Illiaquer M, Cattoir V, Zahar JR
Stenotrophomonas maltophilia--the most worrisome threat among unusual non-fermentative gram-negative bacilli from hospitalized patients: a prospective multicenter study.
The Journal of Infection 2012, 64, 391-398.

Jacquier H, Le Monnier A, Carbonnelle E, Corvec S, Illiaquer M, Bille E, Zahar JR, Jauréguy F, Fihman V, Tankovic J, Cattoir V, GSG
In vitro antimicrobial activity of "last-resort" antibiotics against unusual nonfermenting Gram-negative bacilli clinical isolates.
Microbial Drug Resistance (Larchmont, N.Y.) 2012, 18, 396-401.

Couloigner V, Levy C, François M, Bidet P, Hausdorff WP, Pascal T, Boucherat M, Bingen E, Mariani P, Pierrot S, Bille E, Carbonnelle E, Varon E, Cohen R
Pathogens implicated in acute otitis media failures after 7-valent pneumococcal conjugate vaccine implementation in France: distribution, serotypes, and resistance levels.
The Pediatric Infectious Disease Journal 2012, 31, 154-158.


Jaureguy F, Landraud L, Passet V, Diancourt L, Frapy E, Guigon G, Carbonnelle E, Lortholary O, Clermont O, Denamur E, Picard B, Nassif X, Brisse S
Phylogenetic and genomic diversity of human bacteremic Escherichia coli strains.
BMC genomics 2008, 9, 560.