Members

  First name: Francoise
  Last name: Jauréguy
  Function: Member of INSERM Research Team “Infection, Antimicrobiens, Mod
  Email: francoise.jaureguy
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inserm.fr

Research interest


After having studied on the epidemiology of Tuberculosis in Seine Saint Denis using PCR-based typing methods (spoligotyping and MIRUs) to identify specific strains of Mycobacterium tuberculosis, I worked on the influence of phylogenetic background, virulence factors, antibiotic susceptibility and host determinants on the initial severity and outcome of Escherichia coli bacteraemia. Since ten years, I serve as hospital practicioner and I have focused my interest on antimicrobial stewardship and the role of the bacteriological laboratory to optimize antibiotic treatment using rapid diagnostic tests and the restriction of antibiotic susceptibility reporting, particularly.

Education

Degree

2007, Ph. D. in Cellular and Molecular Biology, Sorbonne Paris Nord University
2011, Pharm D. Paris 11 University


Academic positions

2001-2007 : Assistant Professor, Service de Microbiologie Clinique, Hôpital Avicenne, Groupe Hospitalier Paris Seine Saint-Denis, Assistance Publique des Hôpitaux de Paris, and Paris 13 University
2008- 2015 : Associate Professor, Service de Microbiologie Clinique, Hôpital Avicenne, Groupe Hospitalier Paris Seine Saint-Denis, Assistance Publique-Hôpitaux de Paris and Paris 13 University
2015- present : Clinical Microbiologist, Service de Microbiologie Clinique, Hôpital Avicenne, Groupe Hospitalier Paris Seine Saint-Denis, Assistance Publique-Hôpitaux de Paris



List of the main publications

Méchaï F, Kolakowska A, Carbonnelle E, Bouchaud O, Tresallet C, Jaureguy F
Intra-abdominal abscesses: Microbiological epidemiology and empirical antibiotherapy.
Infectious Diseases Now 2023, 53, 104604.

Halouani H, Lomont A, Jaureguy F, Carbonnelle E, Seytre D, Zahar JR
Interest of broth enrichment for rectal screening in a low carbapenemase-producing Enterobacterales prevalence country.
The Journal of Hospital Infection 2023, 138, 97-98.

Siebert M, Lhomme C, Carbonnelle E, Trésallet C, Kolakowska A, Jaureguy F
Microbiological epidemiology and antibiotic susceptibility of infected meshes after prosthetic abdominal wall repair.
Journal of Visceral Surgery 2023, 160, 85-89.

Pineros N, Tenaillon K, Marin J, Berry V, Jaureguy F, Ghelfenstein-Ferreira T, Carbonnelle E, Lescat M
Using gamification to improve engagement and learning outcomes in medical microbiology: the case study of 'BacteriaGame'.
FEMS microbiology letters 2023, 370, fnad034.

Magréault S, Charbit J, Berkane N, Jaureguy F, Carbonnelle E, Cosson E, Jullien V, Bihan H
Usefulness of Therapeutic Drug Monitoring to Manage Clindamycin-Rifampicin Interaction in a Patient with Diabetic Foot Osteomyelitis.
Therapeutic Drug Monitoring 2023, 45, 703-706.

Burgaya J, Marin J, Royer G, Condamine B, Gachet B, Clermont O, Jaureguy F, Burdet C, Lefort A, de Lastours V, Denamur E, Galardini M, Blanquart F, Colibafi/Septicoli & Coliville groups
The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans.
PLoS genetics 2023, 19, e1010842.

Kolakowska A, El Alaoui F, Ben Alba H, Challal S, Carbonnelle E, Jaureguy F
Vaginal microbiota as an unusual cause of spondylodiscitis.
Archives of Gynecology and Obstetrics 2022, 306, 109-114.

Magréault S, Jaureguy F, Zahar JR, Méchaï F, Toinon D, Cohen Y, Carbonnelle E, Jullien V
Automated HPLC-MS/MS assay for the simultaneous determination of ten plasma antibiotic concentrations.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2022, 1211, 123496.

Magréault S, Jauréguy F, Carbonnelle E, Zahar JR
When and How to Use MIC in Clinical Practice?.
Antibiotics (Basel, Switzerland) 2022, 11, 1748.

Farfour E, Dortet L, Guillard T, Chatelain N, Poisson A, Mizrahi A, Fournier D, Bonnin RA, Degand N, Morand P, Janvier F, Fihman V, Corvec S, Broutin L, Le Brun C, Yin N, Héry-Arnaud G, Grillon A, Bille E, Jean-Pierre H, Amara M, Jaureguy F, Isnard C, Cattoir V, Diedrich T, Flevin E, Merens A, Jacquier H, Vasse M, On Behalf Of The Gmc Study Group n
Antimicrobial Resistance in Enterobacterales Recovered from Urinary Tract Infections in France.
Pathogens (Basel, Switzerland) 2022, 11, 356.

Bonnin RA, Bernabeu S, Jaureguy F, Naas T, Dortet L
MCR-8 mediated colistin resistance in a carbapenem-resistant Klebsiella pneumoniae isolated from a repatriated patient from Morocco.
International Journal of Antimicrobial Agents 2020, 55, 105920.

Saliba R, Neulier C, Seytre D, Fiacre A, Faibis F, Leduc P, Amara M, Jauréguy F, Carbonnelle E, Zahar JR, Marty L
Can real-time polymerase chain reaction allow a faster recovery of hospital activity in cases of an incidental discovery of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant Enterococci carriers?.
Journal of Hospital Infection 2019, 103, 115-120.

La Combe B, Bleibtreu A, Messika J, Fernandes R, Clermont O, Branger C, Billard-Pomares T, Barnaud G, Magdoud F, Eveillard M, Kouatchet A, Lasocki S, Asfar P, Corvec S, Lakhal K, Armand-Lefevre L, Wolff M, Timsit JF, Bourdon S, Reignier J, Martin S, Fihman V, de Prost N, Bador J, Charles PE, Goret J, Boyer A, Wallet F, Jaillette E, Nseir S, Landraud L, Ruimy R, Danin PE, Dellamonica J, Cremniter J, Frat JP, Jauréguy F, Clec'h C, Decré D, Maury E, Dreyfuss D, Denamur E, Ricard JD
Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients.
Intensive Care Medicine 2018, 44, 531-533.

Jauréguy F, Mansour H, Bigot J, Walewski V, Billard-Pomares T, Rahajamanana L, Picard B, Carbonnelle E
Use of the Xpert CarbaR assay for direct detection of carbapenemase genes from blood cultures and urine samples.
The Journal of Hospital Infection 2018, 98, 245-246.

Billard-Pomares T, Rouyer C, Walewski V, Badell-Ocando E, Dumas M, Zumelzu C, Jaureguy F, Brisse S, Caux F, Bouchaud O, Carbonnelle E
Diagnosis in France of a Non-Toxigenic tox Gene-Bearing Strain of Corynebacterium diphtheriae in a Young Male Back From Senegal.
Open Forum Infectious Diseases 2017, 4, ofw271.

Jauréguy F, Chariot P, Vessières A, Picard B
Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections detected by real-time PCR among individuals reporting sexual assaults in the Paris, France area.
Forensic Science International 2016, 266, 130-133.

Walewski V, Méchaï F, Billard-Pomares T, Juguet W, Jauréguy F, Picard B, Tandjaoui-Lambiotte Y, Carbonnelle E, Bouchaud O
MALDI-TOF MS contribution to diagnosis of melioidosis in a nonendemic country in three French travellers.
New Microbes and New Infections 2016, 12, 31-34.

Massot M, Daubie AS, Clermont O, Jaureguy F, Couffignal C, Dahbi G, Mora A, Blanco J, Branger C, Mentre F, Eddi A, Picard B, Denamur E, The Coliville G
Phylogenetic, virulence and antibiotic resistance characteristics of commensal strain populations of Escherichia coli from community subjects in the Paris area in 2010 and evolution over 30 years.
Microbiology 2016, 162, 642-50.

Bourgeois-Nicolaos N, Jaureguy F, Pozzi-Gaudin S, Masson C, Guillet-Caruba C, Lavisse F, Larmignat P, Benachi A, Picard B, Doucet-Populaire F
Benefits of Rapid Molecular Diagnosis of Chlamydia Trachomatis and Neisseria Gonorrhoeae Infections in Women Attending Family Planning Clinics.
Sexually Transmitted Diseases 2015, 42, 652-653.

Lepeule R, Leflon-Guibout V, Vanjak D, Zahar JR, Lafaurie M, Besson C, Lefort A, Groupe des Référents en Infectiologie d’Île-de-France (GRIF)
Clinical spectrum of urine cultures positive for ESBL-producing Escherichia coli in hospitalized patients and impact on antibiotic use.
Medecine Et Maladies Infectieuses 2014, 44, 530-534.

Potron A, Nordmann P, Rondinaud E, Jaureguy F, Poirel L
A mosaic transposon encoding OXA-48 and CTX-M-15: towards pan-resistance.
The Journal of Antimicrobial Chemotherapy 2013, 68, 476-477.

Landraud L, Jauréguy F, Frapy E, Guigon G, Gouriou S, Carbonnelle E, Clermont O, Denamur E, Picard B, Lemichez E, Brisse S, Nassif X
Severity of Escherichia coli bacteraemia is independent of the intrinsic virulence of the strains assessed in a mouse model.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2013, 19, 85-90.

Smati M, Clermont O, Le Gal F, Schichmanoff O, Jauréguy F, Eddi A, Denamur E, Picard B, Coliville Group
Real-time PCR for quantitative analysis of human commensal Escherichia coli populations reveals a high frequency of subdominant phylogroups.
Applied and Environmental Microbiology 2013, 79, 5005-5012.


Exhaustive list of publications

2023


Méchaï F, Kolakowska A, Carbonnelle E, Bouchaud O, Tresallet C, Jaureguy F
Intra-abdominal abscesses: Microbiological epidemiology and empirical antibiotherapy.
Infectious Diseases Now 2023, 53, 104604.

Halouani H, Lomont A, Jaureguy F, Carbonnelle E, Seytre D, Zahar JR
Interest of broth enrichment for rectal screening in a low carbapenemase-producing Enterobacterales prevalence country.
The Journal of Hospital Infection 2023, 138, 97-98.

Siebert M, Lhomme C, Carbonnelle E, Trésallet C, Kolakowska A, Jaureguy F
Microbiological epidemiology and antibiotic susceptibility of infected meshes after prosthetic abdominal wall repair.
Journal of Visceral Surgery 2023, 160, 85-89.

Pineros N, Tenaillon K, Marin J, Berry V, Jaureguy F, Ghelfenstein-Ferreira T, Carbonnelle E, Lescat M
Using gamification to improve engagement and learning outcomes in medical microbiology: the case study of 'BacteriaGame'.
FEMS microbiology letters 2023, 370, fnad034.

Magréault S, Charbit J, Berkane N, Jaureguy F, Carbonnelle E, Cosson E, Jullien V, Bihan H
Usefulness of Therapeutic Drug Monitoring to Manage Clindamycin-Rifampicin Interaction in a Patient with Diabetic Foot Osteomyelitis.
Therapeutic Drug Monitoring 2023, 45, 703-706.

Burgaya J, Marin J, Royer G, Condamine B, Gachet B, Clermont O, Jaureguy F, Burdet C, Lefort A, de Lastours V, Denamur E, Galardini M, Blanquart F, Colibafi/Septicoli & Coliville groups
The bacterial genetic determinants of Escherichia coli capacity to cause bloodstream infections in humans.
PLoS genetics 2023, 19, e1010842.

Chaïbi K, Jaureguy F, Do Rego H, Ruiz P, Mory C, El Helali N, Mrabet S, Mizrahi A, Zahar JR, Pilmis B
What to Do with the New Antibiotics?.
Antibiotics (Basel, Switzerland) 2023, 12, 654.

Eid R, Zahar JR, Ait Ali C, Mizrahi A, Ibrahim R, Banh E, Halouani H, Jauréguy F, Pilmis B, Saliba R
Bloodstream Infections: Comparison of Diagnostic Methods and Therapeutic Consequences between a Hospital in a Resource-Limited Setting and Two French Hospitals.
Microorganisms 2023, 11, 2136.

2022


Kolakowska A, El Alaoui F, Ben Alba H, Challal S, Carbonnelle E, Jaureguy F
Vaginal microbiota as an unusual cause of spondylodiscitis.
Archives of Gynecology and Obstetrics 2022, 306, 109-114.

Magréault S, Jaureguy F, Zahar JR, Méchaï F, Toinon D, Cohen Y, Carbonnelle E, Jullien V
Automated HPLC-MS/MS assay for the simultaneous determination of ten plasma antibiotic concentrations.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2022, 1211, 123496.

Magréault S, Jauréguy F, Carbonnelle E, Zahar JR
When and How to Use MIC in Clinical Practice?.
Antibiotics (Basel, Switzerland) 2022, 11, 1748.

Farfour E, Dortet L, Guillard T, Chatelain N, Poisson A, Mizrahi A, Fournier D, Bonnin RA, Degand N, Morand P, Janvier F, Fihman V, Corvec S, Broutin L, Le Brun C, Yin N, Héry-Arnaud G, Grillon A, Bille E, Jean-Pierre H, Amara M, Jaureguy F, Isnard C, Cattoir V, Diedrich T, Flevin E, Merens A, Jacquier H, Vasse M, On Behalf Of The Gmc Study Group n
Antimicrobial Resistance in Enterobacterales Recovered from Urinary Tract Infections in France.
Pathogens (Basel, Switzerland) 2022, 11, 356.

2020


Bonnin RA, Bernabeu S, Jaureguy F, Naas T, Dortet L
MCR-8 mediated colistin resistance in a carbapenem-resistant Klebsiella pneumoniae isolated from a repatriated patient from Morocco.
International Journal of Antimicrobial Agents 2020, 55, 105920.

2019


Saliba R, Neulier C, Seytre D, Fiacre A, Faibis F, Leduc P, Amara M, Jauréguy F, Carbonnelle E, Zahar JR, Marty L
Can real-time polymerase chain reaction allow a faster recovery of hospital activity in cases of an incidental discovery of carbapenemase-producing Enterobacteriaceae and vancomycin-resistant Enterococci carriers?.
Journal of Hospital Infection 2019, 103, 115-120.

2018


La Combe B, Bleibtreu A, Messika J, Fernandes R, Clermont O, Branger C, Billard-Pomares T, Barnaud G, Magdoud F, Eveillard M, Kouatchet A, Lasocki S, Asfar P, Corvec S, Lakhal K, Armand-Lefevre L, Wolff M, Timsit JF, Bourdon S, Reignier J, Martin S, Fihman V, de Prost N, Bador J, Charles PE, Goret J, Boyer A, Wallet F, Jaillette E, Nseir S, Landraud L, Ruimy R, Danin PE, Dellamonica J, Cremniter J, Frat JP, Jauréguy F, Clec'h C, Decré D, Maury E, Dreyfuss D, Denamur E, Ricard JD
Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients.
Intensive Care Medicine 2018, 44, 531-533.

Jauréguy F, Mansour H, Bigot J, Walewski V, Billard-Pomares T, Rahajamanana L, Picard B, Carbonnelle E
Use of the Xpert CarbaR assay for direct detection of carbapenemase genes from blood cultures and urine samples.
The Journal of Hospital Infection 2018, 98, 245-246.

2017


Billard-Pomares T, Rouyer C, Walewski V, Badell-Ocando E, Dumas M, Zumelzu C, Jaureguy F, Brisse S, Caux F, Bouchaud O, Carbonnelle E
Diagnosis in France of a Non-Toxigenic tox Gene-Bearing Strain of Corynebacterium diphtheriae in a Young Male Back From Senegal.
Open Forum Infectious Diseases 2017, 4, ofw271.

2016


Jauréguy F, Chariot P, Vessières A, Picard B
Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae infections detected by real-time PCR among individuals reporting sexual assaults in the Paris, France area.
Forensic Science International 2016, 266, 130-133.

Walewski V, Méchaï F, Billard-Pomares T, Juguet W, Jauréguy F, Picard B, Tandjaoui-Lambiotte Y, Carbonnelle E, Bouchaud O
MALDI-TOF MS contribution to diagnosis of melioidosis in a nonendemic country in three French travellers.
New Microbes and New Infections 2016, 12, 31-34.

Massot M, Daubie AS, Clermont O, Jaureguy F, Couffignal C, Dahbi G, Mora A, Blanco J, Branger C, Mentre F, Eddi A, Picard B, Denamur E, The Coliville G
Phylogenetic, virulence and antibiotic resistance characteristics of commensal strain populations of Escherichia coli from community subjects in the Paris area in 2010 and evolution over 30 years.
Microbiology 2016, 162, 642-50.

2015


Bourgeois-Nicolaos N, Jaureguy F, Pozzi-Gaudin S, Masson C, Guillet-Caruba C, Lavisse F, Larmignat P, Benachi A, Picard B, Doucet-Populaire F
Benefits of Rapid Molecular Diagnosis of Chlamydia Trachomatis and Neisseria Gonorrhoeae Infections in Women Attending Family Planning Clinics.
Sexually Transmitted Diseases 2015, 42, 652-653.

2014


Shoai Tehrani M, Hajage D, Fihman V, Tankovic J, Cau S, Day N, Visseaux C, Carbonnelle E, Kouatchet A, Cattoir V, Nhan TX, Corvec S, Jacquier H, Jauréguy F, Le Monnier A, Morand P, Zahar JR, on behalf the Groupe de microbiologie clinique
Gram-negative bacteremia: which empirical antibiotic therapy?.
Médecine Et Maladies Infectieuses 2014, 44, 159-166.

2013


Mattioni S, Develoux M, Brun S, Martin A, Jaureguy F, Naggara N, Bouchaud O
Management of mycetomas in France.
Médecine Et Maladies Infectieuses 2013, 43, 286-294.

Potron A, Nordmann P, Rondinaud E, Jaureguy F, Poirel L
A mosaic transposon encoding OXA-48 and CTX-M-15: towards pan-resistance.
The Journal of Antimicrobial Chemotherapy 2013, 68, 476-477.

Landraud L, Jauréguy F, Frapy E, Guigon G, Gouriou S, Carbonnelle E, Clermont O, Denamur E, Picard B, Lemichez E, Brisse S, Nassif X
Severity of Escherichia coli bacteraemia is independent of the intrinsic virulence of the strains assessed in a mouse model.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2013, 19, 85-90.

Smati M, Clermont O, Le Gal F, Schichmanoff O, Jauréguy F, Eddi A, Denamur E, Picard B, Coliville Group
Real-time PCR for quantitative analysis of human commensal Escherichia coli populations reveals a high frequency of subdominant phylogroups.
Applied and Environmental Microbiology 2013, 79, 5005-5012.

2012


Mellon G, Clec'h C, Picard B, Cohen Y, Jauréguy F
Postsurgical meningitis due to multiresistant Acinetobacter baumannii successfully treated with high doses of ampicillin/sulbactam combined with rifampicin and fosfomycin.
Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy 2012, 18, 958-960.

Fihman V, Le Monnier A, Corvec S, Jaureguy F, Tankovic J, Jacquier H, Carbonnelle E, Bille E, Illiaquer M, Cattoir V, Zahar JR
Stenotrophomonas maltophilia--the most worrisome threat among unusual non-fermentative gram-negative bacilli from hospitalized patients: a prospective multicenter study.
The Journal of Infection 2012, 64, 391-398.

Jacquier H, Le Monnier A, Carbonnelle E, Corvec S, Illiaquer M, Bille E, Zahar JR, Jauréguy F, Fihman V, Tankovic J, Cattoir V, Gmc Study Group
In vitro antimicrobial activity of "last-resort" antibiotics against unusual nonfermenting Gram-negative bacilli clinical isolates.
Microbial Drug Resistance (Larchmont, N.Y.) 2012, 18, 396-401.

2009


Jauréguy F
[Host and bacterial determinants of Escherichia coli extra intestinal infections]..
Medecine sciences : M/S 2009, 25, 221-223.

Jauréguy F
[Escherichia coli: evolution of antibiotic resistance in urban settings]..
La Revue du praticien 2009, 59, 455-457.

2008


Jaureguy F, Landraud L, Passet V, Diancourt L, Frapy E, Guigon G, Carbonnelle E, Lortholary O, Clermont O, Denamur E, Picard B, Nassif X, Brisse S
Phylogenetic and genomic diversity of human bacteremic Escherichia coli strains.
BMC genomics 2008, 9, 560.

2007


Radu DM, Jauréguy F, Seguin A, Foulon C, Destable MD, Azorin J, Martinod E
Postoperative pneumonia after major pulmonary resections: an unsolved problem in thoracic surgery..
The Annals of thoracic surgery 2007, 84, 1669-1673.

2006


Clec'h C, Jauréguy F, Hamza L, Karoubi P, Fosse JP, Hamdi A, Vincent F, Gonzalez F, Cohen Y
Agreement between quantitative cultures of postintubation tracheal aspiration and plugged telescoping catheter, protected specimen brush, or BAL for the diagnosis of nosocomial pneumonia..
Chest 2006, 130, 956-961.

2004


Jauréguy F, Carton M, Panel P, Foucaud P, Butel MJ, Doucet-Populaire F
Effects of intrapartum penicillin prophylaxis on intestinal bacterial colonization in infants..
Journal of clinical microbiology 2004, 42, 5184-5188.