Members
![]() | First name: Laurence Last name: Armand-Lefèvre Function: Clinical microbiologist Position: Full professor Email: laurence.armand aphp.fr |
Research interest
My work is focused on the emergence of antibiotic resistance in microbiota. Microbiota are exposed to antibiotics during each and every antibiotic treatments whatever is the reason of their use. Acquisition and dissemination of resistant bacteria which result from these exposure lead in turn to both infections in the colonized hosts and dissemination of resistance in the environment. We try to understand better the dynamic of these phenomena by combining specifically designed epidemiological studies and in-depth genetic analysis of the isolates. Studies are focused on “bacteria/resistance” associations which cause the current major burden in bacterial infections i.e. extended-spectrum beta-lactamase (ESBL-E) and/or carbapenemase producing Enterobacterales, particularly Escherichia coli.
I actively participated and participate in the conduct of projects concerning the acquisition and transmission of multi-drug resistant Enterobacterales in hospital (PREV-BLSE, MALI), during travel or military mission (VOYAG-R, MARC) or after antibiotic exposure in high prevalence countries (NIGER), and in a context of "One-Health" surveillance (TRICYCLE Madagascar, JPIAMR-fund TRIUMPH).
Furthermore, as clinical microbiologist, I am working with collaborators to test new rapid diagnosis methods that can help decrease the emergence of resistance in microbiota.
Education
Degree
2009 : PhD. in Microbiology, Paris Sud University
1999 : Pharm D. and specialisation in Clinical Biology, Paris Descartes University
1998 : Master of Sc. in Microbiology, Paris Descartes University
1989-1993 : First and second cycle of Pharmaceutical school, Paris Descartes University
Academic positions
2015- 2016 : Deputy head of Bacteriology laboratory, Bichat Hospital, AP-HP Nord Paris Cité University, Paris
2003-2014 : Microbiologist practitioner at Bacteriology laboratory, Bichat Hospital, Paris Diderot University
2001-2003 : Assistant Professor in Bacteriology, Paris Diderot University
1999-2001 : Assistant Professor in Bacteriology, Paris Ouest University
1993-1999 : Resident in clinical biology, Paris Descartes University
Research training (post doctoral)
2013 – today : Member of EVRest research team, IAME, Paris Diderot University.
– 2005-2013 : Member of research team, EA3964, Paris Diderot University.
List of the main publications
Simultaneous Hospital Outbreaks of New Delhi Metallo-β-Lactamase-Producing Enterobacterales Unraveled Using Whole-Genome Sequencing.
Microbiology Spectrum 2022, 10, e0228721.
Maataoui N, Chemali L, Patrier J, Tran Dinh A, Le Fèvre L, Lortat-Jacob B, Marzouk M, d'Humières C, Rondinaud E, Ruppé E, Montravers P, Timsit JF, Armand-Lefèvre L
Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2021, 40, 2227-2234.
Armand-Lefèvre L, Rondinaud E, Desvillechabrol D, Mullaert J, Clermont O, Petitjean M, Ruppe E, Cokelaer T, Bouchier C, Tenaillon O, Ma L, Nooroya Y, Matheron S, The Voyag-R Study Group n, Andremont A, Denamur E, Kennedy SP
Dynamics of extended-spectrum beta-lactamase-producing Enterobacterales colonization in long-term carriers following travel abroad.
Microbial Genomics 2021, 7, 000576.
d'Humières C, Patrier J, Lortat-Jacob B, Tran-Dinh A, Chemali L, Maataoui N, Rondinaud E, Ruppé E, Burdet C, Ruckly S, Montravers P, Timsit JF, Armand-Lefevre L
Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France.
PloS One 2021, 16, e0250728.
Milenkov M, Rasoanandrasana S, Rahajamanana LV, Rakotomalala RS, Razafindrakoto CA, Rafalimanana C, Ravelomandranto E, Ravaoarisaina Z, Westeel E, Petitjean M, Mullaert J, Clermont O, Raskine L, Samison LH, Endtz H, Andremont A, Denamur E, Komurian-Pradel F, Armand-Lefevre L
Prevalence, Risk Factors, and Genetic Characterization of Extended-Spectrum Beta-Lactamase Escherichia coli Isolated From Healthy Pregnant Women in Madagascar.
Frontiers in Microbiology 2021, 12, 786146.
Monard C, Pehlivan J, Auger G, Alviset S, Tran Dinh A, Duquaire P, Gastli N, d'Humières C, Maamar A, Boibieux A, Baldeyrou M, Loubinoux J, Dauwalder O, Cattoir V, Armand-Lefèvre L, Kernéis S, Asg
Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia.
Critical Care (London, England) 2020, 24, 434.
Exhaustive list of publications
2022
Ruppé E, d'Humières C, Armand-Lefèvre L
Inferring antibiotic susceptibility from metagenomic data: dream or reality?.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2022, 28, 1225-1229.
Rondinaud E, Clermont O, Petitjean M, Ruppe E, Esposito-Farèse M, Nazimoudine A, VRsg, Coignard B, Matheron S, Andremont A, Denamur E, Armand-Lefevre L
Acquisition of Enterobacterales carrying the colistin resistance gene mcr following travel to the tropics.
Journal of Travel Medicine 2022, taac141.
Tran-Dinh A, Slassi L, De Tymowski C, Assadi M, Tanaka S, Zappella N, Lortat Jacob B, Jean-Baptiste S, Atchade E, Castier Y, Mal H, Mordant P, Armand-Lefèvre L, Messika J, Grall N, Montravers P
Secondary Prophylaxis With Inhaled Colistin to Prevent Recurrence of Pseudomonas aeruginosa and Extended-spectrum β-lactamase-producing Enterobacterales Pneumonia in ICU After Lung Transplantation: A Before-and-after Retrospective Cohort Analysis.
Transplantation 2022, 106, 2232-2240.
Lo S, Lolom I, Goldstein V, Petitjean M, Rondinaud E, Bunel-Gourdy V, Tran Dinh A, Wicky PH, Ruppé E, d'Humières C, Lucet JC, Armand-Lefèvre L
Simultaneous Hospital Outbreaks of New Delhi Metallo-β-Lactamase-Producing Enterobacterales Unraveled Using Whole-Genome Sequencing.
Microbiology Spectrum 2022, 10, e0228721.
Patrier J, Villageois-Tran K, Szychowiak P, Ruckly S, Gschwind R, Wicky PH, Gueye S, Armand-Lefevre L, Marzouk M, Sonneville R, Bouadma L, Petitjean M, Lamara F, de Montmollin E, Timsit JF, Ruppé E, FCCSG
Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults.
Critical Care (London, England) 2022, 26, 300.
Habib A, Lo S, Villageois-Tran K, Petitjean M, Malik SA, Armand-Lefèvre L, Ruppé E, Zahra R
Dissemination of carbapenemase-producing Enterobacterales in the community of Rawalpindi, Pakistan.
PloS One 2022, 17, e0270707.
d'Humières C, Gaïa N, Gueye S, de Lastours V, Leflon-Guibout V, Maataoui N, Duprilot M, Lecronier M, Rousseau MA, Gamany N, Lescure FX, Senard O, Deconinck L, Dollat M, Isernia V, Le Hur AC, Petitjean M, Nazimoudine A, Le Gac S, Chalal S, Ferreira S, Lazarevic V, Guigon G, Gervasi G, Armand-Lefèvre L, Schrenzel J, Ruppé E
Contribution of Clinical Metagenomics to the Diagnosis of Bone and Joint Infections.
Frontiers in Microbiology 2022, 13, 863777.
Ferré VM, Bachelard A, Zaidi M, Armand-Lefevre L, Descamps D, Charpentier C, Ghosn J
Detection of Monkeypox Virus in Anorectal Swabs From Asymptomatic Men Who Have Sex With Men in a Sexually Transmitted Infection Screening Program in Paris, France.
Annals of Internal Medicine 2022, 175, 1491-1492.
2021
Maataoui N, Chemali L, Patrier J, Tran Dinh A, Le Fèvre L, Lortat-Jacob B, Marzouk M, d'Humières C, Rondinaud E, Ruppé E, Montravers P, Timsit JF, Armand-Lefèvre L
Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2021, 40, 2227-2234.
Deconinck L, Gschwind R, Petitjean M, Gueye S, Leflon-Guibout V, Maataoui N, Rondinaud E, Suard A, Gallais K, Richaud R, Fuchs A, Iung B, Alkhoder S, Ismaël S, Herrou J, Prié H, Armand-Lefèvre L, d'Humières C, Ruppé E
Endocarditis caused by Thalassospira sp.
IDCases 2021, 24, e01109.
Buchan BW, Armand-Lefevre L, Anderson N
Molecular Diagnosis of Pneumonia (Including Multiplex Panels).
Clinical Chemistry 2021, 68, 59-68.
Kerneis S, Visseaux B, Armand-Lefevre L, Timsit JF
Molecular diagnostic methods for pneumonia: how can they be applied in practice?.
Current Opinion in Infectious Diseases 2021, 34, 118-125.
Armand-Lefèvre L, Rondinaud E, Desvillechabrol D, Mullaert J, Clermont O, Petitjean M, Ruppe E, Cokelaer T, Bouchier C, Tenaillon O, Ma L, Nooroya Y, Matheron S, The Voyag-R Study Group n, Andremont A, Denamur E, Kennedy SP
Dynamics of extended-spectrum beta-lactamase-producing Enterobacterales colonization in long-term carriers following travel abroad.
Microbial Genomics 2021, 7, 000576.
Voiriot G, Fartoukh M, Durand-Zaleski I, Berard L, Rousseau A, Armand-Lefevre L, Verdet C, Argaud L, Klouche K, Megarbane B, Patrier J, Richard JC, Reignier J, Schwebel C, Souweine B, Tandjaoui-Lambiotte Y, Simon T, Timsit JF, MCsg
Combined use of a broad-panel respiratory multiplex PCR and procalcitonin to reduce duration of antibiotics exposure in patients with severe community-acquired pneumonia (MULTI-CAP): a multicentre, parallel-group, open-label, individual randomised trial conducted in French intensive care units.
BMJ open 2021, 11, e048187.
d'Humières C, Patrier J, Lortat-Jacob B, Tran-Dinh A, Chemali L, Maataoui N, Rondinaud E, Ruppé E, Burdet C, Ruckly S, Montravers P, Timsit JF, Armand-Lefevre L
Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France.
PloS One 2021, 16, e0250728.
Milenkov M, Rasoanandrasana S, Rahajamanana LV, Rakotomalala RS, Razafindrakoto CA, Rafalimanana C, Ravelomandranto E, Ravaoarisaina Z, Westeel E, Petitjean M, Mullaert J, Clermont O, Raskine L, Samison LH, Endtz H, Andremont A, Denamur E, Komurian-Pradel F, Armand-Lefevre L
Prevalence, Risk Factors, and Genetic Characterization of Extended-Spectrum Beta-Lactamase Escherichia coli Isolated From Healthy Pregnant Women in Madagascar.
Frontiers in Microbiology 2021, 12, 786146.
2020
Andremont O, Armand-Lefevre L, Dupuis C, de Montmollin E, Ruckly S, Lucet JC, Smonig R, Magalhaes E, Ruppé E, Mourvillier B, Lebut J, Lermuzeaux M, Sonneville R, Bouadma L, Timsit JF, Cnc
Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.
Intensive Care Medicine 2020, 46, 1232-1242.
Rondinaud E, Ruppé E, Matheron S, Lucet JC, Armand-Lefevre L, VRsg
Screening methods for intestinal carriage of multidrug-resistant Enterobacterales: interest of enrichment broth.
Diagnostic Microbiology and Infectious Disease 2020, 97, 115079.
Benchetrit L, Mathy V, Armand-Lefevre L, Bouadma L, Timsit JF
Successful treatment of septic shock due to NDM-1-producing Klebsiella pneumoniae using ceftazidime/avibactam combined with aztreonam in solid organ transplant recipients: report of two cases.
International Journal of Antimicrobial Agents 2020, 55, 105842.
Berbescu S, Matt M, Dinh A, Simeon S, Noussair L, Armand-Lefevre L, Davido B
Successful treatment of meningococcal bacteremia using oral doxycycline: A case report.
International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 2020, 92, 78-80.
Jolivet S, Lolom I, Bailly S, Bouadma L, Lortat-Jacob B, Montravers P, Armand-Lefevre L, Timsit JF, Lucet JC
Impact of colonization pressure on acquisition of extended-spectrum β-lactamase-producing Enterobacterales and meticillin-resistant Staphylococcus aureus in two intensive care units: a 19-year retrospective surveillance.
The Journal of Hospital Infection 2020, 105, 10-16.
Sevin T, Goldstein V, Lolom I, Lenne F, Gaudonnet Y, Baptiste AL, Bendjelloul G, Armand-Lefevre L, Lucet JC
Bathroom contamination by antibiotic-resistant Enterobacterales (ESBLPE and CPE): an experimental study.
The Journal of Hospital Infection 2020, 106, 271-276.
Lecuru M, Nicolas-Chanoine MH, Tanaka S, Montravers P, Armand-Lefevre L, Denamur E, Mammeri H
Emergence of Imipenem Resistance in a CpxA-H208P-Variant-Producing Proteus mirabilis Clinical Isolate.
Microbial Drug Resistance (Larchmont, N.Y.) 2020
Maataoui N, Langendorf C, Berthe F, Bayjanov JR, van Schaik W, Isanaka S, Grais RF, Clermont O, Andremont A, Armand-Lefèvre L, Woerther PL
Increased risk of acquisition and transmission of ESBL-producing Enterobacteriaceae in malnourished children exposed to amoxicillin.
The Journal of Antimicrobial Chemotherapy 2020, 75, 709-717.
Peiffer-Smadja N, Bouadma L, Mathy V, Allouche K, Patrier J, Reboul M, Montravers P, Timsit JF, Armand-Lefevre L
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia.
Critical Care (London, England) 2020, 24, 366.
Monard C, Pehlivan J, Auger G, Alviset S, Tran Dinh A, Duquaire P, Gastli N, d'Humières C, Maamar A, Boibieux A, Baldeyrou M, Loubinoux J, Dauwalder O, Cattoir V, Armand-Lefèvre L, Kernéis S, Asg
Multicenter evaluation of a syndromic rapid multiplex PCR test for early adaptation of antimicrobial therapy in adult patients with pneumonia.
Critical Care (London, England) 2020, 24, 434.
Fontaine C, Armand-Lefèvre L, Magnan M, Nazimoudine A, Timsit JF, Ruppé E
Relationship between the composition of the intestinal microbiota and the tracheal and intestinal colonization by opportunistic pathogens in intensive care patients.
PloS One 2020, 15, e0237260.
Pierre-Audigier C, Talla C, Alame-Emane AK, Audigier B, Grall N, Ruimy R, Andremont A, Cadet-Daniel V, Sola C, Takiff H, Gicquel B, Vray M, Armand-Lefevre L
Tuberculosis trends in a hot-spot region in Paris, France.
The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease 2020, 24, 428-435.
2019
Maataoui N, Mayet A, Duron S, Delacour H, Mentré F, Laouenan C, Desvillechabrol D, Cokelaer T, Meynard JB, Ducher A, Andremont A, Armand-Lefèvre L, Mérens A
High acquisition rate of extended-spectrum β-lactamase-producing Enterobacteriaceae among French military personnel on mission abroad, without evidence of inter-individual transmission.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019, 25, 631.e1-631.e9.
Huttner BD, de Lastours V, Wassenberg M, Maharshak N, Mauris A, Galperine T, Zanichelli V, Kapel N, Bellanger A, Olearo F, Duval X, Armand-Lefevre L, Carmeli Y, Bonten M, Fantin B, Harbarth S, RGWsg
A 5-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae: a randomized clinical trial.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019, 25, 830-838.
Leo S, Lazarevic V, Gaïa N, Estellat C, Girard M, Matheron S, Armand-Lefèvre L, Andremont A, Schrenzel J, Ruppé E
The intestinal microbiota predisposes to traveler's diarrhea and to the carriage of multidrug-resistant Enterobacteriaceae after traveling to tropical regions.
Gut Microbes 2019, 10, 631-641.
La Combe B, Clermont O, Messika J, Eveillard M, Kouatchet A, Lasocki S, Corvec S, Lakhal K, Billard-Pomares T, Fernandes R, Armand-Lefevre L, Bourdon S, Reignier J, Fihman V, de Prost N, Bador J, Goret J, Wallet F, Denamur E, Ricard JD, Cg, CG
Pneumonia-Specific Escherichia coli with Distinct Phylogenetic and Virulence Profiles, France, 2012-2014.
Emerging Infectious Diseases 2019, 25, 710-718.
2018
La Combe B, Bleibtreu A, Messika J, Fernandes R, Clermont O, Branger C, Billard-Pomares T, Barnaud G, Magdoud F, Eveillard M, Kouatchet A, Lasocki S, Asfar P, Corvec S, Lakhal K, Armand-Lefevre L, Wolff M, Timsit JF, Bourdon S, Reignier J, Martin S, Fihman V, de Prost N, Bador J, Charles PE, Goret J, Boyer A, Wallet F, Jaillette E, Nseir S, Landraud L, Ruimy R, Danin PE, Dellamonica J, Cremniter J, Frat JP, Jauréguy F, Clec'h C, Decré D, Maury E, Dreyfuss D, Denamur E, Ricard JD
Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients.
Intensive Care Medicine 2018, 44, 531-533.
Jolivet S, Lescure FX, Armand-Lefevre L, Raffoul R, Dilly MP, Ghodbane W, Nataf P, Lucet JC
Surgical site infection with extended-spectrum β-lactamase-producing Enterobacteriaceae after cardiac surgery: incidence and risk factors.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 283-288.
Ruppe E, Burdet C, Grall N, de Lastours V, Lescure FX, Andremont A, Armand-Lefevre L
Impact of antibiotics on the intestinal microbiota needs to be re-defined to optimize antibiotic usage.
Clin Microbiol Infect 2018, 24, 3-5.
Jolivet S, Vaillant L, Poncin T, Lolom I, Gaudonnet Y, Rondinaud E, Bendjelloul G, Lomont A, Lucet JC, Armand-Lefèvre L
Prevalence of carriage of extended-spectrum β-lactamase-producing enterobacteria and associated factors in a French hospital.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 1311-1314.
Peiffer-Smadja N, Abbara S, Rizk N, Pogliaghi M, Rondinaud E, Tesmoingt C, Massias L, Lucet JC, Alkhoder S, Armand-Lefèvre L, Lescure FX
High-dose daptomycin in patients with infective endocarditis or sternal wound infections.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 1106-1108.
Lemaignen A, Armand-Lefevre L, Birgand G, Mabileau G, Lolom I, Ghodbane W, Dilly MP, Nataf P, Lucet JC
Thirteen-year experience with universal Staphylococcus aureus nasal decolonization prior to cardiac surgery: a quasi-experimental study.
The Journal of Hospital Infection 2018, 100, 322-328.
Armand-Lefèvre L, Andremont A, Ruppé E
Travel and acquisition of multidrug-resistant Enterobacteriaceae.
Medecine Et Maladies Infectieuses 2018, 48, 431-441.
Ruppé E, Andremont A, Armand-Lefèvre L
Digestive tract colonization by multidrug-resistant Enterobacteriaceae in travellers: An update.
Travel Medicine and Infectious Disease 2018, 21, 28-35.
de Gunzburg J, Ghozlane A, Ducher A, Le Chatelier E, Duval X, Ruppe E, Armand-Lefevre L, Sablier-Gallis F, Burdet C, Alavoine L, Chachaty E, Augustin V, Varastet M, Levenez F, Kennedy S, Pons N, Mentre F, Andremont A
Protection of the Human Gut Microbiome From Antibiotics.
J Infect Dis 2018, 217, 628-636.
Lorme F, Maataoui N, Rondinaud E, Esposito-Farèse M, Clermont O, Ruppe E, Arlet G, Genel N, VRsg, Matheron S, Andremont A, Armand-Lefevre L
Acquisition of plasmid-mediated cephalosporinase producing Enterobacteriaceae after a travel to the tropics.
PloS One 2018, 13, e0206909.
2017
Grall N, Lazarevic V, Gaia N, Couffignal C, Laouenan C, Ilic-Habensus E, Wieder I, Plesiat P, Angebault C, Bougnoux ME, Armand-Lefevre L, Andremont A, Duval X, Schrenzel J
Unexpected persistence of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the faecal microbiota of hospitalised patients treated with imipenem.
Int J Antimicrob Agents 2017, 50, 81-87.
Armand-Lefevre L, Ruppé E, Andremont A
ESBL-producing Enterobacteriaceae in travellers: doctors beware.
The Lancet. Infectious Diseases 2017, 17, 8-9.
Sangare SA, Rondinaud E, Maataoui N, Maiga AI, Guindo I, Maiga A, Camara N, Dicko OA, Dao S, Diallo S, Bougoudogo F, Andremont A, Maiga II, Armand-Lefevre L
Very high prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae in bacteriemic patients hospitalized in teaching hospitals in Bamako, Mali.
PloS One 2017, 12, e0172652.
Sangaré SA, Maïga AI, Maïga A, Diallo S, Camara N, Savadogo S, Guindo I, Bougoudogo F, Armand-Lefèvre L, Andremont A, Maïga II
Prevalence of extended-spectrum beta-lactamase phenotypes in enterobacteria isolated from blood cultures of patients at admission to the University Hospital of Bamako.
Medecine Et Sante Tropicales 2017, 27, 170-175.
2016
Bernard J, Armand-Lefèvre L, Luce E, El Mniai A, Chau F, Casalino E, Andremont A, Ruppé E
Impact of a short exposure to levofloxacin on faecal densities and relative abundance of total and quinolone-resistant Enterobacteriaceae.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2016, 22, 646.e1-4.
Birgand G, Leroy C, Nerome S, Luong Nguyen LB, Lolom I, Armand-Lefevre L, Ciotti C, Lecorre B, Marcade G, Fihman V, Nicolas-Chanoine MH, Pelat C, Perozziello A, Fantin B, Yazdanpanah Y, Ricard JD, Lucet JC
Costs associated with implementation of a strict policy for controlling spread of highly resistant microorganisms in France.
BMJ open 2016, 6, e009029.
Voiriot G, Visseaux B, Cohen J, Nguyen LB, Neuville M, Morbieu C, Burdet C, Radjou A, Lescure FX, Smonig R, Armand-Lefevre L, Mourvillier B, Yazdanpanah Y, Soubirou JF, Ruckly S, Houhou-Fidouh N, Timsit JF
Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia.
Crit Care 2016, 20, 375.
Sangare SA, Maiga AI, Guindo I, Maiga A, Camara N, Dicko OA, Diallo S, Bougoudogo F, Armand-Lefevre L, Andremont A, Maiga II
Prevalence of ESBL-producing Enterobacteriaceae isolated from blood cultures in Mali.
Journal of Infection in Developing Countries 2016, 10, 1059-1064.
2015
Bretonnière C, Leone M, Milési C, Allaouchiche B, Armand-Lefevre L, Baldesi O, Bouadma L, Decré D, Figueiredo S, Gauzit R, Guery B, Joram N, Jung B, Lasocki S, Lepape A, Lesage F, Pajot O, Philippart F, Souweine B, Tattevin P, Timsit JF, Vialet R, Zahar JR, Misset B, Bedos JP
Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
Intensive Care Medicine 2015, 41, 1181-1196.
Burdet C, Pajot O, Couffignal C, Armand-Lefèvre L, Foucrier A, Laouénan C, Wolff M, Massias L, Mentré F
Population pharmacokinetics of single-dose amikacin in critically ill patients with suspected ventilator-associated pneumonia.
European Journal of Clinical Pharmacology 2015, 71, 75–83.
Parienti JJ, Lucet JC, Lefort A, Armand-Lefèvre L, Wolff M, Caron F, Cattoir V, Yazdanpanah Y
Empirical therapies among adults hospitalized for community-acquired upper urinary tract infections: A decision-tree analysis of mortality, costs, and resistance.
American Journal of Infection Control 2015, 43, e53-e59.
Le Dorze M, Gault N, Foucrier A, Ruppé E, Mourvillier B, Woerther PL, Birgand G, Montravers P, Dilly MP, Tubach F, Andremont A, Timsit JF, Wolff M, Armand-Lefèvre L
Performance and impact of a rapid method combining mass spectrometry and direct antimicrobial susceptibility testing on treatment adequacy of patients with ventilator-associated pneumonia.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015, 21, 468.e1-6.
Lemaignen A, Birgand G, Ghodhbane W, Alkhoder S, Lolom I, Belorgey S, Lescure FX, Armand-Lefevre L, Raffoul R, Dilly MP, Nataf P, Lucet JC
Sternal wound infection after cardiac surgery: incidence and risk factors according to clinical presentation.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015, 21, 674.e11-18.
Bonnal C, Birgand G, Lolom I, Diamantis S, Dumortier C, L'Heriteau F, Armand-Lefevre L, Lucet JC
Staphylococcus aureus healthcare associated bacteraemia: An indicator of catheter related infections.
Medecine Et Maladies Infectieuses 2015, 45, 84-88.
Lefébure A, Papy E, Rioux C, Diamantis S, Armand-Lefèvre L, Longuet P, Lescure FX, Wolff M, Arnaud P, Lucet JC
Audit of carbapenem prescriptions comparing 2 assessment periods.
Medecine Et Maladies Infectieuses 2015, 45, 273-278.
Sangare SA, Maiga AI, Guindo I, Maiga A, Camara N, Savadogo S, Diallo S, Bougoudogo F, Armand-Lefevre L, Andremont A, Maiga II
Prevalence of extended-spectrum beta-lactamase-producing Enterobacteriaceae isolated from blood cultures in Africa.
Médecine Et Maladies Infectieuses 2015, 45, 374-382.
Ruppé E, Armand-Lefèvre L, Estellat C, Consigny PH, El Mniai A, Boussadia Y, Goujon C, Ralaimazava P, Campa P, Girard PM, Wyplosz B, Vittecoq D, Bouchaud O, Le Loup G, Pialoux G, Perrier M, Wieder I, Moussa N, Esposito-Farèse M, Hoffmann I, Coignard B, Lucet JC, Andremont A, Matheron S
High Rate of Acquisition but Short Duration of Carriage of Multidrug-Resistant Enterobacteriaceae After Travel to the Tropics.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2015, 61, 593-600.
Pajot O, Burdet C, Couffignal C, Massias L, Armand-Lefevre L, Foucrier A, Da Silva D, Lasocki S, Laouénan C, Mentec H, Mentré F, Wolff M
Impact of imipenem and amikacin pharmacokinetic/pharmacodynamic parameters on microbiological outcome of Gram-negative bacilli ventilator-associated pneumonia.
The Journal of Antimicrobial Chemotherapy 2015, 70, 1487–1494.
Dubert M, Pourbaix A, Alkhoder S, Mabileau G, Lescure FX, Ghodhbane W, Belorgey S, Rioux C, Armand-Lefèvre L, Wolff M, Raffoul R, Nataf P, Yazdanpanah Y, Lucet JC
Sternal Wound Infection after Cardiac Surgery: Management and Outcome.
PloS One 2015, 10, e0139122.
Loubet P, Lescure FX, Lepage L, Kirsch M, Armand-Lefevre L, Bouadma L, Lariven S, Duval X, Yazdanpanah Y, Joly V
Endocarditis due to gram-negative bacilli at a French teaching hospital over a 6-year period: clinical characteristics and outcome.
Infectious Diseases (London, England) 2015, 47, 889-895.
2014
Amsallem M, Iung B, Bouleti C, Armand-Lefevre L, Eme AL, Touati A, Kirsch M, Duval X, Vahanian A
First reported human case of native mitral infective endocarditis caused by Streptococcus canis.
The Canadian Journal of Cardiology 2014, 30, 1462.e1–2.
Marc F, Esquirol C, Papy E, Longuet P, Armand-Lefevre L, Rioux C, Diamantis S, Dumortier C, Bourgeois-Nicolaos N, Lucet JC, Wolff M, Arnaud P
A retrospective study of daptomycin use in a Paris teaching-hospital.
Médecine et maladies infectieuses 2014, 44, 25-31.
Neulier C, Birgand G, Ruppé E, Armand-Lefèvre L, Lolom I, Yazdanpanah Y, Lucet JC, Andremont A
Enterobacteriaceae bacteremia: Risk factors for ESBLPE.
Médecine et maladies infectieuses 2014, 44, 32-38.
Birgand G, Schwarzinger M, Perozziello A, Lolom I, Pelat C, Armand-Lefevre L, Buzzi JC, Andremont A, Yazdanpanah Y, Lucet JC
Prolonged hospital stay, an adverse effect of strict national policy for controlling the spread of highly resistant microorganisms.
Infection Control and Hospital Epidemiology 2014, 35, 1427-1429.
Birgand G, Armand-Lefevre L, Lepainteur M, Lolom I, Neulier C, Reibel F, Yazdanpanah Y, Andremont A, Lucet JC
Introduction of highly resistant bacteria into a hospital via patients repatriated or recently hospitalized in a foreign country.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases [RESEARCH NOTE] 2014, 20, O887-890.
Couffignal C, Pajot O, Laouénan C, Burdet C, Foucrier A, Wolff M, Armand-Lefevre L, Mentré F, Massias L
Population pharmacokinetics of imipenem in critically ill patients with suspected ventilator-associated pneumonia and evaluation of dosage regimens.
British Journal of Clinical Pharmacology 2014, 78, 1022–1034.
Ruppe E, Armand-Lefevre L, Estellat C, El-Mniai A, Boussadia Y, Consigny P, Girard P, Vittecoq D, Bouchaud O, Pialoux G, Esposito-Farese M, Coignard B, Lucet J, Andremont A, Matheron S
Acquisition of carbapenemase-producing Enterobacteriaceae by healthy travellers to India, France, February 2012 to March 2013.
Euro surveillance: bulletin Européen sur les maladies transmissibles = European communicable disease bulletin 2014, 19,
2013
Birgand G, Armand-Lefevre L, Lolom I, Ruppe E, Andremont A, Lucet JC
Duration of colonization by extended-spectrum β-lactamase-producing Enterobacteriaceae after hospital discharge.
American Journal of Infection Control 2013, 41, 443-447.
Defrance G, Birgand G, Ruppé E, Billard M, Ruimy R, Bonnal C, Andremont A, Armand-Lefèvre L
Time-to-positivity-based discrimination between Enterobacteriaceae, Pseudomonas aeruginosa and strictly anaerobic Gram-negative bacilli in aerobic and anaerobic blood culture vials.
Journal of Microbiological Methods 2013, 93, 77-79.
Ruppé E, Lixandru B, Cojocaru R, Büke C, Paramythiotou E, Angebault C, Visseaux C, Djuikoue I, Erdem E, Burduniuc O, El Mniai A, Marcel C, Perrier M, Kesteman T, Clermont O, Denamur E, Armand-Lefèvre L, Andremont A
Relative fecal abundance of extended-spectrum-β-lactamase-producing Escherichia coli strains and their occurrence in urinary tract infections in women.
Antimicrobial Agents and Chemotherapy 2013, 57, 4512-4517.
Armand-Lefevre L, Angebault C, Barbier F, Hamelet E, Defrance G, Ruppe E, Bronchard R, Lepeule R, Lucet JC, El Mniai A, Wolff M, Montravers P, Plesiat P, Andremont A
Emergence of Imipenem-Resistant Gram-Negative Bacilli in Intestinal Flora of Intensive Care Patients.
Antimicrobial Agents and Chemotherapy 2013, 57, 1488-1495.
Birgand G, Ruimy R, Schwarzinger M, Lolom I, Bendjelloul G, Houhou N, Armand-Lefevre L, Andremont A, Yazdanpanah Y, Lucet JC
Rapid detection of glycopeptide-resistant enterococci: impact on decision-making and costs.
Antimicrobial Resistance and Infection Control 2013, 2, 30.
2012
Roux D, Huy C, Lolom I, Andremont A, Arlet G, Armand-Lefevre L, Lucet JC
Diversity of extended-spectrum β-lactamase-producing Enterobacteriaceae on hospital admission.
Scandinavian Journal of Infectious Diseases 2012, 44, 231-236.
2011
Woerther PL, Angebault C, Jacquier H, Hugede HC, Janssens AC, Sayadi S, El Mniai A, Armand-Lefèvre L, Ruppé E, Barbier F, Raskine L, Page AL, de Rekeneire N, Andremont A
Massive increase, spread, and exchange of extended spectrum β-lactamase-encoding genes among intestinal Enterobacteriaceae in hospitalized children with severe acute malnutrition in Niger.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2011, 53, 677-685.
2003
Armand-Lefèvre L, Leflon-Guibout V, Bredin J, Barguellil F, Amor A, Pagès JM, Nicolas-Chanoine MH
Imipenem resistance in Salmonella enterica serovar Wien related to porin loss and CMY-4 beta-lactamase production.
Antimicrobial Agents and Chemotherapy 2003, 47, 1165-1168.
Hanslik T, Hartig C, Jurand C, Armand-Lefevre L, Jubault V, Rouveix E, Dubourg O, Prinseau J, Baglin A, Nicolas-Chanoine MH
Clinical significance of tolerant strains of streptococci in adults with infective endocarditis.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2003, 9, 852-857.
2002
Heym B, Le Moal M, Armand-Lefevre L, Nicolas-Chanoine MH
Multilocus sequence typing (MLST) shows that the 'Iberian' clone of methicillin-resistant Staphylococcus aureus has spread to France and acquired reduced susceptibility to teicoplanin.
The Journal of Antimicrobial Chemotherapy 2002, 50, 323-329.