First name: Sara
  Last name: Dion
  Function: Animal Technician
  Email: sara.dion

Research interest

Exhaustive list of publications


Royer G, Clermont O, Marin J, Condamine B, Dion S, Blanquart F, Galardini M, Denamur E
Epistatic interactions between the high pathogenicity island and other iron uptake systems shape Escherichia coli extra-intestinal virulence.
Nature Communications 2023, 14, 3667.


Su WL, Bredèche MF, Dion S, Dauverd J, Condamine B, Gutierrez A, Denamur E, Matic I
TisB Protein Protects Escherichia coli Cells Suffering Massive DNA Damage from Environmental Toxic Compounds.
mBio 2022, 13, e0038522.


Clermont O, Condamine B, Dion S, Gordon DM, Denamur E
The E phylogroup of Escherichia coli is highly diverse and mimics the whole E. coli species population structure.
Environmental Microbiology 2021, 23, 7139-7151.

Bridier-Nahmias A, Launay A, Bleibtreu A, Magnan M, Walewski V, Chatel J, Dion S, Robbe-Saule V, Clermont O, Norel F, Denamur E, Tenaillon O
Escherichia coli Genomic Diversity within Extraintestinal Acute Infections Argues for Adaptive Evolution at Play.
mSphere 2021, 6, e01176-20.


Duprilot M, Baron A, Blanquart F, Dion S, Pouget C, Lettéron P, Flament-Simon SC, Clermont O, Denamur E, Nicolas-Chanoine MH
Success of Escherichia coli O25b:H4 Sequence Type 131 Clade C Associated with a Decrease in Virulence.
Infection and Immunity 2020, 88, e00576-20.

Galardini M, Clermont O, Baron A, Busby B, Dion S, Schubert S, Beltrao P, Denamur E
Major role of iron uptake systems in the intrinsic extra-intestinal virulence of the genus Escherichia revealed by a genome-wide association study.
PLoS genetics 2020, 16, e1009065.


d'Humières C, Touchon M, Dion S, Cury J, Ghozlane A, Garcia-Garcera M, Bouchier C, Ma L, Denamur E, P C Rocha E
A simple, reproducible and cost-effective procedure to analyse gut phageome: from phage isolation to bioinformatic approach.
Scientific Reports 2019, 9, 11331.

Clermont O, Dixit OVA, Vangchhia B, Condamine B, Dion S, Bridier-Nahmias A, Denamur E, Gordon D
Characterization and rapid identification of phylogroup G in Escherichia coli, a lineage with high virulence and antibiotic resistance potential.
Environmental Microbiology 2019, 21, 3107-3117.

Ghalayini M, Magnan M, Dion S, Zatout O, Bourguignon L, Tenaillon O, Lescat M
Long-term evolution of the natural isolate of Escherichia coli 536 in the mouse gut colonized after maternal transmission reveals convergence in the constitutive expression of the lactose operon.
Molecular Ecology 2019, 28, 4470-4485.

Billard-Pomares T, Clermont O, Castellanos M, Magdoud F, Royer G, Condamine B, Fouteau S, Barbe V, Roche D, Cruveiller S, Médigue C, Pognard D, Glodt J, Dion S, Rigal O, Picard B, Denamur E, Branger C
The Arginine Deiminase Operon Is Responsible for a Fitness Trade-Off in Extended-Spectrum-β-Lactamase-Producing Strains of Escherichia coli.
Antimicrobial Agents and Chemotherapy 2019, 63,


Tourret J, Willing BP, Dion S, MacPherson J, Denamur E, Finlay BB
Immunosuppressive Treatment Alters Secretion of Ileal Antimicrobial Peptides and Gut Microbiota, and Favors Subsequent Colonization by Uropathogenic Escherichia coli.
Transplantation 2017, 101, 74-82.

Lescat M, Launay A, Ghalayini M, Magnan M, Glodt J, Pintard C, Dion S, Denamur E, Tenaillon O
Using long-term experimental evolution to uncover the patterns and determinants of molecular evolution of an Escherichia coli natural isolate in the streptomycin-treated mouse gut.
Molecular Ecology 2017, 26, 1802-1817.


Dufour N, Clermont O, La Combe B, Messika J, Dion S, Khanna V, Denamur E, Ricard J, Debarbieux L, ColoColi group
Bacteriophage LM33_P1, a fast-acting weapon against the pandemic ST131-O25b:H4 Escherichia coli clonal complex..
Journal of Antimicrobial Chemotherapy 2016, 71, 3072.

Skurnik D, Clermont O, Guillard T, Launay A, Danilchanka O, Pons S, Diancourt L, Lebreton F, Kadlec K, Roux D, Jiang D, Dion S, Ashard H, Denamur M, Cywes-Bentley C, Schwarz S, Tenaillon O, Andremont A, Picard B, Mekalanos J, Brisse S, Denamur E
Emergence of Antimicrobial-Resistant Escherichia coli of Animal Origin Spreading in Humans.
Molecular Biology and Evolution 2016, 33, 898.

Tourret J, Willing BP, Croxen MA, Dufour N, Dion S, Wachtel S, Denamur E, Finlay BB
Small Intestine Early Innate Immunity Response during Intestinal Colonization by Escherichia coli Depends on Its Extra-Intestinal Virulence Status.
PloS One 2016, 11, e0153034.


DeLalio LJ, Dion SM, Bootes AM, Smith WA
Direct effects of hypoxia and nitric oxide on ecdysone secretion by insect prothoracic glands..
Journal of insect physiology 2015, 76, 56-66.

Rossi B, Soubirou J, Chau F, Massias L, Dion S, Lepeule R, Fantin B, Lefort A
Cefotaxime and Amoxicillin-Clavulanate Synergism against Extended-Spectrum-β-Lactamase-Producing Escherichia coli in a Murine Model of Urinary Tract Infection.
Antimicrobial Agents and Chemotherapy 2015, 32, 1708.


Lefort A, Chau F, Lepeule R, Dubée V, Kitzis MD, Dion S, Fantin B
Activity of fosfomycin alone or combined with cefoxitin in vitro and in vivo in a murine model of urinary tract infection due to Escherichia coli harbouring CTX-M-15-type extended-spectrum β-lactamase.
International Journal of Antimicrobial Agents 2014, 43, 366-369.

Mora A, Dahbi G, López C, Mamani R, Marzoa J, Dion S, Picard B, Blanco M, Alonso MP, Denamur E, Blanco J
Virulence patterns in a murine sepsis model of ST131 Escherichia coli clinical isolates belonging to serotypes O25b:H4 and O16:H5 are associated to specific virotypes.
PloS One 2014, 9, e87025.

Lescat M, Reibel F, Pintard C, Dion S, Glodt J, Gateau C, Launay A, Ledda A, Cruvellier S, Tourret J, Tenaillon O
The Conserved nhaAR Operon Is Drastically Divergent between B2 and Non-B2 Escherichia coli and Is Involved in Extra-Intestinal Virulence.
PloS One 2014, 9, e108738.


Lescat M, Clermont O, Woerther PL, Glodt J, Dion S, Skurnik D, Djossou F, Dupont C, Perroz G, Picard B, Catzeflis F, Andremont A, Denamur E
Commensal Escherichia coli strains in Guiana reveal a high genetic diversity with host-dependant population structure.
Environmental Microbiology Reports 2013, 5, 49-57.


Tourret J, Aloulou M, Garry L, Tenaillon O, Dion S, Ryffel B, Monteiro RC, Denamur E
The interaction between a non-pathogenic and a pathogenic strain synergistically enhances extra-intestinal virulence in Escherichia coli.
Microbiology (Reading, England) 2011, 157, 774-785.