2014. Doctor of Philosophy (PhD) Université Paris Diderot.
2010. Board certification in Infectious and Tropical Diseases, Université Pierre et Marie Curie
2007. Board certification in Internal Medicine, Université Pierre et Marie Curie-Paris
2007. Doctorate in Medicine (M.D), Université Pierre et Marie Curie
2005. Masters in Science (MSc), Experimental Virology, Pasteur Institut and University Paris Diderot
1997. B.A in Biological and Medical Sciences. Statistics and Epidemiology. University Pierre et Marie Curie

2015-current. Associate Professor in Internal Medicine, Université Paris Diderot Medical School, Internal Medicine Departement, Beaujon Hospital, Clichy and IAME Research Group, UMR1137, INSERM and Université Paris Diderot.
2013-2015 Visiting scholar, Molecular epidemiology of Infectious Diseases (MAC-EPID) Lab, University of Michigan School of Public Health (Pr Betsy Foman) , Ann Arbor, Michigan, USA

2011-2013 Doctoral Student, EA3964 research Team, (Pr Bruno Fantin), University Paris Diderot Medical School, Paris, France.

de Lastours V, Fantin B
[Pyogenic brain abscesses in adults].
La Revue De Medecine Interne / Fondee ... Par La Societe Nationale Francaise De Medecine Interne 2016

Galy A, Lepeule R, Goulenok T, Buzele R, de Lastours V, Fantin B
Presentation and impact of catheter-associated thrombosis in patients with infected long-term central venous catheters: a prospective bicentric observational study.
Annals of Medicine 2016, 48, 182-189.

Munier AL, de Lastours V, Barbier F, Chau F, Fantin B, Ruimy R
Comparative dynamics of the emergence of fluoroquinolone resistance in staphylococci from the nasal microbiota of patients treated with fluoroquinolones according to their environment.
International Journal of Antimicrobial Agents 2015

de Lastours V, Fantin B
Impact of fluoroquinolones on human microbiota. Focus on the emergence of antibiotic resistance.
Future Microbiology 2015, 10, 1241-1255.

de Lastours V, Fantin B
[Resistance to fluoroquinolones in 2013: what are the consequences in internal medicine?].
La Revue De Médecine Interne / Fondée ... Par La Société Nationale Francaise De Médecine Interne 2014, 35, 601-608.

de Lastours V, Bleibtreu A, Chau F, Burdet C, Duval X, Denamur E, Fantin B
Quinolone-resistant Escherichia coli from the faecal microbiota of healthy volunteers after ciprofloxacin exposure are highly adapted to a commensal lifestyle.
The Journal of Antimicrobial Chemotherapy 2014, 69, 761-768.

de Lastours V, Chau F, Roy C, Larroque B, Fantin B
Emergence of quinolone resistance in the microbiota of hospitalized patients treated or not with a fluoroquinolone.
The Journal of Antimicrobial Chemotherapy 2014

Ruppe E, Pitsch A, Tubach F, de Lastours V, Chau F, Pasquet B, Lucet JC, Andremont A, Fantin B
Clinical predictive values of extended-spectrum beta-lactamase carriage in patients admitted to medical wards.
European Journal of Clinical Microbiology & Infectious Diseases 2012, 31, 319-325.

de Lastours V, Kalamarides M, Leflon V, Rodallec M, Vilgrain V, Nicolas-Chanoine MH, Fantin B
Optimization of bacterial diagnosis yield after needle aspiration in immunocompetent adults with brain abscesses.
Neurosurgery 2008, 63, 362-367; discussion 367-368.

2022

Sokal A, Chawki S, Nguyen Y, Sauvanet A, Ponsot P, Maire F, Fantin B, de Lastours V
Specificities of acute cholangitis in patients with cancer: a retrospective comparative study of 130 episodes.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2022, 41, 143-146.

Lemaitre M, Galy A, de Lastours V, Thill P, Tattevin P, Lefort A
The intravenous vancomycin prescription practices of French infectious disease specialists: A cross-sectional observational study.
Infectious Diseases Now 2022, 52, 414-417.

de Lastours V, El Meouche I, Chau F, Beghain J, Chevret D, Aubert-Frambourg A, Clermont O, Royer G, Bouvet O, Denamur E, Fantin B, CG
Evolution of fluoroquinolone-resistant Escherichia coli in the gut after ciprofloxacin treatment.
International journal of medical microbiology: IJMM 2022, 312, 151548.

Perisse E, Mageau A, Brandberg Y, Gardeur L, Gresteau V, Mroz A, Reversat M, Roullier E, Stojicic D, Belmir L, Leblanc C, Goulenok T, de Lastours V, Teixeira M, Moins-Teisserenc H, Sacré K, DPN
[Attitude and beliefs of healthcare workers toward influenza vaccination in Internal Medicine: A cross-sectional survey].
La Revue De Medecine Interne 2022, 43, 342-346.

Bouzid D, Mirault T, Ghazali A, Muller L, Casalino E, Peiffer Smadja N, Auber B, Guerin M, Sambet CH, Etienne I, De Lastours V, Badoual C, Lemogne C, Ruszniewski P, Université Paris Cité' Osce Study Group n, Faye A, Tran Dinh A
Feasibility of large-scale eOSCES: the simultaneous evaluation of 500 medical students during a mock examination.
Medical Education Online 2022, 27, 2084261.

Royer G, Clermont O, Condamine B, Mercier-Darty M, Laouénan C, Lefort A, Denamur E, de Lastours V, CaSG
O-Antigen Targeted Vaccines Against Escherichia coli May Be Useful in Reducing Morbidity, Mortality, and Antimicrobial Resistance.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2022, 74, 364-366.

Denamur E, Condamine B, Esposito-Farèse M, Royer G, Clermont O, Laouenan C, Lefort A, de Lastours V, Galardini M, C, Sg
Genome wide association study of Escherichia coli bloodstream infection isolates identifies genetic determinants for the portal of entry but not fatal outcome.
PLoS genetics 2022, 18, e1010112.

d'Humières C, Gaïa N, Gueye S, de Lastours V, Leflon-Guibout V, Maataoui N, Duprilot M, Lecronier M, Rousseau MA, Gamany N, Lescure FX, Senard O, Deconinck L, Dollat M, Isernia V, Le Hur AC, Petitjean M, Nazimoudine A, Le Gac S, Chalal S, Ferreira S, Lazarevic V, Guigon G, Gervasi G, Armand-Lefèvre L, Schrenzel J, Ruppé E
Contribution of Clinical Metagenomics to the Diagnosis of Bone and Joint Infections.
Frontiers in Microbiology 2022, 13, 863777.

2021

Dinh A, Duran C, Ropers J, Bouchand F, Davido B, Deconinck L, Matt M, Senard O, Lagrange A, Mellon G, Calin R, Makhloufi S, de Lastours V, Mathieu E, Kahn JE, Rouveix E, Grenet J, Dumoulin J, Chinet T, Pépin M, Delcey V, Diamantis S, Benhamou D, Vitrat V, Dombret MC, Guillemot D, Renaud B, Claessens YE, Labarère J, Aegerter P, Bedos JP, Crémieux AC, PST(SG
Factors Associated With Treatment Failure in Moderately Severe Community-Acquired Pneumonia: A Secondary Analysis of a Randomized Clinical Trial.
JAMA network open 2021, 4, e2129566.

Chawki S, Sokal A, Duprilot M, Henry A, Leflon-Guibout V, Nicolas-Chanoine MH, Fantin B, de Lastours V
Temocillin as an alternative treatment for acute bacterial cholangitis: a retrospective microbiology susceptibility-based study of 140 episodes.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2021

Dinh A, Ropers J, Duran C, Davido B, Deconinck L, Matt M, Senard O, Lagrange A, Makhloufi S, Mellon G, de Lastours V, Bouchand F, Mathieu E, Kahn JE, Rouveix E, Grenet J, Dumoulin J, Chinet T, Pépin M, Delcey V, Diamantis S, Benhamou D, Vitrat V, Dombret MC, Renaud B, Perronne C, Claessens YE, Labarère J, Bedos JP, Aegerter P, Crémieux AC, PST(SG
Discontinuing β-lactam treatment after 3 days for patients with community-acquired pneumonia in non-critical care wards (PTC): a double-blind, randomised, placebo-controlled, non-inferiority trial.
Lancet (London, England) 2021, 397, 1195-1203.

Le Menestrel A, Guerin F, Chau F, Massias L, Benchetrit L, Cattoir V, Fantin B, de Lastours V
Activity of the combination of colistin and fosfomycin against NDM-1-producing Escherichia coli with variable levels of susceptibility to colistin and fosfomycin in a murine model of peritonitis.
The Journal of Antimicrobial Chemotherapy 2021, 77, 155-163.

Royer G, Darty MM, Clermont O, Condamine B, Laouenan C, Decousser JW, Vallenet D, Lefort A, de Lastours V, Denamur E, CaSg
Phylogroup stability contrasts with high within sequence type complex dynamics of Escherichia coli bloodstream infection isolates over a 12-year period.
Genome Medicine 2021, 13, 77.

Matet A, Fournel L, Gaillard F, Amar L, Arlet JB, Baron S, Bats AS, Buffel du Vaure C, Charlier C, De Lastours V, Faye A, Jablon E, Kadlub N, Leguen J, Lebeaux D, Malmartel A, Mirault T, Planquette B, Régent A, Thebault JL, Dinh AT, Nuzzo A, Turc G, Friedlander G, Ruszniewski P, Badoual C, Ranque B, Oualha M, Courbebaisse M
Impact of integrating objective structured clinical examination into academic student assessment: Large-scale experience in a French medical school.
PloS One 2021, 16, e0245439.

2020

de Lastours V, Poirel L, Huttner B, Harbarth S, Denamur E, Nordmann P
Emergence of colistin-resistant Gram-negative Enterobacterales in the gut of patients receiving oral colistin and neomycin decontamination.
The Journal of Infection 2020, 80, 578-606.

de Lastours V, Laouénan C, Royer G, Carbonnelle E, Lepeule R, Esposito-Farèse M, Clermont O, Duval X, Fantin B, Mentré F, Decousser JW, Denamur E, Lefort A
Mortality in Escherichia coli bloodstream infections: antibiotic resistance still does not make it.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2334-2343.

Cheminet G, de Lastours V, Poirel L, Chau F, Peoc'h K, Massias L, Fantin B, Nordmann P
Dimercaptosuccinic acid in combination with carbapenems against isogenic strains of Escherichia coli producing or not producing a metallo-β-lactamase in vitro and in murine peritonitis.
The Journal of Antimicrobial Chemotherapy 2020, 75, 3593-3600.

Lafont E, Roux O, de Lastours V, Dokmak S, Leflon V, Fantin B, Lefort A
Pyogenic liver abscess in liver transplant recipient: A warning signal for the risk of recurrence and retransplantation.
Transplant Infectious Disease: An Official Journal of the Transplantation Society 2020, 22, e13360.

Roujansky A, de Lastours V, Guérin F, Chau F, Cheminet G, Massias L, Cattoir V, Fantin B
Analysis of Paradoxical Efficacy of Carbapenems against Carbapenemase-Producing Escherichia coli in a Murine Model of Lethal Peritonitis.
Antimicrobial Agents and Chemotherapy 2020, 64,

Herrou J, De Lastours V
Predictive factors of pneumocystis pneumonia in patients with rheumatic diseases exposed to prolonged high-dose glucocorticoids.
Annals of the Rheumatic Diseases 2020, 79, e23.

Mahévas M, Tran VT, Roumier M, Chabrol A, Paule R, Guillaud C, Fois E, Lepeule R, Szwebel TA, Lescure FX, Schlemmer F, Matignon M, Khellaf M, Crickx E, Terrier B, Morbieu C, Legendre P, Dang J, Schoindre Y, Pawlotsky JM, Michel M, Perrodeau E, Carlier N, Roche N, de Lastours V, Ourghanlian C, Kerneis S, Ménager P, Mouthon L, Audureau E, Ravaud P, Godeau B, Gallien S, Costedoat-Chalumeau N
Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data.
BMJ 2020, m1844.

Nuzzo A, Tran-Dinh A, Courbebaisse M, Peyre H, Plaisance P, Matet A, Ranque B, Faye A, de Lastours V, UoPOaSg
Improved clinical communication OSCE scores after simulation-based training: Results of a comparative study.
PloS One 2020, 15, e0238542.

Leo S, Lazarevic V, Girard M, Gaïa N, Schrenzel J, de Lastours V, Fantin B, Bonten M, Carmeli Y, Rondinaud E, Harbarth S, Huttner BD
Metagenomic Characterization of Gut Microbiota of Carriers of Extended-Spectrum Beta-Lactamase or Carbapenemase-Producing Enterobacteriaceae Following Treatment with Oral Antibiotics and Fecal Microbiota Transplantation: Results from a Multicenter Randomized Trial.
Microorganisms 2020

2019

Huttner BD, de Lastours V, Wassenberg M, Maharshak N, Mauris A, Galperine T, Zanichelli V, Kapel N, Bellanger A, Olearo F, Duval X, Armand-Lefevre L, Carmeli Y, Bonten M, Fantin B, Harbarth S, RGWsg
A 5-day course of oral antibiotics followed by faecal transplantation to eradicate carriage of multidrug-resistant Enterobacteriaceae: a randomized clinical trial.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019, 25, 830-838.

Sokal A, Sauvanet A, Fantin B, de Lastours V
Acute cholangitis: Diagnosis and management.
Journal of Visceral Surgery 2019

Ruppé E, Ghozlane A, Tap J, Pons N, Alvarez AS, Maziers N, Cuesta T, Hernando-Amado S, Clares I, Martínez JL, Coque TM, Baquero F, Lanza VF, Máiz L, Goulenok T, de Lastours V, Amor N, Fantin B, Wieder I, Andremont A, van Schaik W, Rogers M, Zhang X, Willems RJL, de Brevern AG, Batto JM, Blottière HM, Léonard P, Léjard V, Letur A, Levenez F, Weiszer K, Haimet F, Doré J, Kennedy SP, Ehrlich SD
Prediction of the intestinal resistome by a three-dimensional structure-based method.
Nature Microbiology 2019, 4, 112-123.

Canouï E, Zarrouk V, Canouï-Poitrine F, Desmoulin U, Leflon V, Allaham W, de Lastours V, Guigui P, Fantin B
Surgery is safe and effective when indicated in the acute phase of hematogenous pyogenic vertebral osteomyelitis.
Infectious Diseases (London, England) 2019, 51, 268-276.

Arangalage D, Abtan J, Gaschignard J, Ceccaldi PF, Remini SA, Etienne I, Ruszniewski P, Plaisance P, De Lastours V, Lefort A, Faye A
Implementation of a large-scale simulation-based cardiovascular clinical examination course for undergraduate medical students - a pilot study.
BMC medical education 2019, 19, 361.

2018

de Lastours V, Goulenok T, Guérin F, Jacquier H, Eyma C, Chau F, Cattoir V, Fantin B
Ceftriaxone promotes the emergence of AmpC-overproducing Enterobacteriaceae in gut microbiota from hospitalized patients.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2018, 37, 417-421.

Ruppe E, Burdet C, Grall N, de Lastours V, Lescure FX, Andremont A, Armand-Lefevre L
Impact of antibiotics on the intestinal microbiota needs to be re-defined to optimize antibiotic usage.
Clin Microbiol Infect 2018, 24, 3-5.

Cheminet G, Kapel N, Bleibtreu A, Sadou-Yaye H, Bellanger A, Duval X, Joly F, Fantin B, de Lastours V, FGfFMT(
Faecal microbiota transplantation with frozen capsules for relapsing Clostridium difficile infections: the first experience from 15 consecutive patients in France.
The Journal of Hospital Infection 2018, 100, 148-151.

de Lastours V
[Should doses of antibiotics be adjusted?].
La Revue De Medecine Interne 2018, 39, 171-177.

Goulenok T, Chopin D, De Lastours V, Zarrouk V, Lepeule R, Fantin B, Lefort A
[Influenzae and pneumococcal vaccination rate in an internal medicine ward].
La Revue De Medecine Interne 2018, 39, 386-392.

Zarrouk V, Gras J, Dubée V, de Lastours V, Lopes A, Leflon V, Allaham W, Guigui P, Fantin B
Increased mortality in patients aged 75 years or over with pyogenic vertebral osteomyelitis.
Infectious Diseases (London, England) 2018, 50, 783-787.

Guery R, Habibi A, Arlet JB, Lionnet F, de Lastours V, Decousser JW, Mainardi JL, Razazi K, Baranes L, Bartolucci P, Godeau B, Galacteros F, Michel M, Mahevas M
Severe, non specific symptoms in non-typhoidal Salmonella infections in adult patients with sickle cell disease: a retrospective multicentre study.
Infectious Diseases (London, England) 2018, 50, 822-830.

Berleur M, Guérin F, Massias L, Chau F, Poujade J, Cattoir V, Fantin B, de Lastours V
Activity of fosfomycin alone or combined with temocillin in vitro and in a murine model of peritonitis due to KPC-3- or OXA-48-producing Escherichia coli.
The Journal of Antimicrobial Chemotherapy 2018, 73, 3074-3080.

Coldiron ME, Assao B, Page AL, Hitchings MDT, Alcoba G, Ciglenecki I, Langendorf C, Mambula C, Adehossi E, Sidikou F, Tassiou EI, De Lastours V, Grais RF
Single-dose oral ciprofloxacin prophylaxis as a response to a meningococcal meningitis epidemic in the African meningitis belt: A 3-arm, open-label, cluster-randomized trial.
PLoS medicine 2018, 15, e1002593.

Rossi B, Gasperini ML, Leflon-Guibout V, Gioanni A, de Lastours V, Rossi G, Dokmak S, Ronot M, Roux O, Nicolas-Chanoine MH, Fantin B, Lefort A
Hypervirulent Klebsiella pneumoniae in Cryptogenic Liver Abscesses, Paris, France.
Emerging Infectious Diseases 2018, 24, 221-229.

2017

Perrineau S, Cazals-Hatem D, Zarrouk V, Fantin B, de Lastours V
Cytomegalovirus-associated protein-losing enteropathy in a healthy man.
Medecine Et Maladies Infectieuses 2017, 47, 562-565.

Abbara S, Georgin-Lavialle S, Bachmeyer C, Hermine O, Launay JM, de Lastours V
[Chronic asthenia and abdominal pain in a 26-year-old woman].
La Revue De Medecine Interne 2017, 38, 850-852.

de Lastours V, Maugy E, Mathy V, Chau F, Rossi B, Guérin F, Cattoir V, Fantin B, CSG
Ecological impact of ciprofloxacin on commensal enterococci in healthy volunteers.
The Journal of Antimicrobial Chemotherapy 2017, 72, 1574-1580.

Richaud C, De Lastours V, Panhard X, Petrover D, Bruno F, Lefort A
Candida vertebral osteomyelitis (CVO) 28 cases from a 10-year retrospective study in France.
Medicine 2017, 96, e7525.

2016

de Lastours V, Fantin B
[Pyogenic brain abscesses in adults].
La Revue De Medecine Interne / Fondee ... Par La Societe Nationale Francaise De Medecine Interne 2016

DE Lastours V, Malosh R, Ramadugu K, Srinivasan U, Dawid S, Ohmit S, Foxman B
Co-colonization by Streptococcus pneumoniae and Staphylococcus aureus in the throat during acute respiratory illnesses.
Epidemiology and Infection 2016, 1-13.

de Lastours V, Chopin D, Jacquier H, d'Humieres C, Burdet C, Chau F, Denamur E, Fantin B
Prospective Cohort Study of the Relative Abundance of Extended-Spectrum-Beta-Lactamase-Producing Escherichia coli in the Gut of Patients Admitted to Hospitals.
Antimicrob Agents Chemother 2016, 60, 6941-6944.

Galy A, Lepeule R, Goulenok T, Buzele R, de Lastours V, Fantin B
Presentation and impact of catheter-associated thrombosis in patients with infected long-term central venous catheters: a prospective bicentric observational study.
Annals of Medicine 2016, 48, 182-189.

2015

Munier AL, de Lastours V, Barbier F, Chau F, Fantin B, Ruimy R
Comparative dynamics of the emergence of fluoroquinolone resistance in staphylococci from the nasal microbiota of patients treated with fluoroquinolones according to their environment.
International Journal of Antimicrobial Agents 2015

de Lastours V, Fantin B
Impact of fluoroquinolones on human microbiota. Focus on the emergence of antibiotic resistance.
Future Microbiology 2015, 10, 1241-1255.

2014

de Lastours V, Fantin B
[Resistance to fluoroquinolones in 2013: what are the consequences in internal medicine?].
La Revue De Médecine Interne / Fondée ... Par La Société Nationale Francaise De Médecine Interne 2014, 35, 601-608.

de Lastours V, Bleibtreu A, Chau F, Burdet C, Duval X, Denamur E, Fantin B
Quinolone-resistant Escherichia coli from the faecal microbiota of healthy volunteers after ciprofloxacin exposure are highly adapted to a commensal lifestyle.
The Journal of Antimicrobial Chemotherapy 2014, 69, 761-768.

de Lastours V, Chau F, Roy C, Larroque B, Fantin B
Emergence of quinolone resistance in the microbiota of hospitalized patients treated or not with a fluoroquinolone.
The Journal of Antimicrobial Chemotherapy 2014

2012

Ruppe E, Pitsch A, Tubach F, de Lastours V, Chau F, Pasquet B, Lucet JC, Andremont A, Fantin B
Clinical predictive values of extended-spectrum beta-lactamase carriage in patients admitted to medical wards.
European Journal of Clinical Microbiology & Infectious Diseases 2012, 31, 319-325.

2008

de Lastours V, Kalamarides M, Leflon V, Rodallec M, Vilgrain V, Nicolas-Chanoine MH, Fantin B
Optimization of bacterial diagnosis yield after needle aspiration in immunocompetent adults with brain abscesses.
Neurosurgery 2008, 63, 362-367; discussion 367-368.