2021: PhD Variabilité de la réponse pharmacologique, modélisation et influence des plans expérimentaux.
2013: Pharm. D. DES « Innovation Pharmaceutique et recherche », Paris Descartes University;
2011 : MSc Biostatistique, Paris Sud University

2023

Picone O, Vivanti AJ, Sibiude J, Cordier AG, Alessandrini V, Kayem G, Borie C, Luton D, Manchon P, Couffignal C, Vauloup Fellous C, Csg
SARS-COV-2 excretion and maternal-fetal transmission: Virological data of French prospective multi-center cohort study COVIPREG during the first wave.
Journal of Gynecology Obstetrics and Human Reproduction 2023, 52, 102547.

2022

Geoffroy PA, Schroder CM, Bourgin P, Maruani J, Lejoyeux M, d'Ortho MP, Couffignal C, SDG
Validation of a data collection set for the psychiatric, addiction, sleep and chronobiological assessments of patients with depression: A Delphi study for the SoPsy-depression French national cohort.
L'Encephale 2022, S0013-7006(22)00210-X.

Huré M, Peyronnet V, Sibiude J, Cazenave MG, Anselem O, Luton D, Vauloup-Fellous C, Deruelle P, Cordier AG, Benachi A, Mandelbrot L, Couffignal C, Pauphilet V, Vivanti AJ, Picone O
[SARS-Cov-2 vaccine's acceptance among pregnant women-A cross-sectional survey].
Gynecologie, Obstetrique, Fertilite & Senologie 2022, S2468-7189(22)00236-7.

Taillé C, Roche N, Tesson F, Tardivon C, Tran VT, Couffignal C
Belief and adherence to COVID 19-lockdown restrictions in patients with asthma versus other chronic diseases: results from a cross-sectional survey nested in the ComPaRe e-cohort, in France.
The Journal of Asthma: Official Journal of the Association for the Care of Asthma 2022, 59, 1491-1500.

Dupont A, Couffignal C, Arias C, Salah K, Phillips-Houlbraq M, Le Brun M, Taillé C
Outcomes and risk factors with COVID-19 or influenza in hospitalized asthma patients.
Respiratory Research 2022, 23, 342.

Egloff C, Couffignal C, Cordier AG, Deruelle P, Sibiude J, Anselem O, Benachi A, Luton D, Mandelbrot L, Vauloup-Fellous C, Vivanti AJ, Picone O
Pregnant women's perceptions of the COVID-19 vaccine: A French survey.
PloS One 2022, 17, e0263512.

2021

Couffignal C, Mentré F, Bertrand J
Impact of study design and statistical model in pharmacogenetic studies with gene-treatment interaction.
CPT: pharmacometrics & systems pharmacology 2021, 10, 340-349.

Boyer P, Couffignal C, Bahman M, Mylle G, Rousseau MA, Dukan R
Displaced three and four part proximal humeral fractures: prospective controlled randomized open-label two-arm study comparing intramedullary nailing and locking plate.
International Orthopaedics 2021

Beauplet B, Soulie O, Niemier JY, Pons-Peyneau C, Belhadi D, Couffignal C, Fossey-Diaz V
Dealing with the lack of evidence to treat depression in older patients with cancer: French Societies of Geriatric Oncology (SOFOG) and PsychoOncology (SFFPO) position paper based on a systematic review.
Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer 2021, 29, 563-571.

Gouel-Cheron A, Elmaleh Y, Couffignal C, Kantor E, Meslin S, Caillard A, Salome A, Hamada S, Cholley B, Mebazaa A, Longrois D, Bourgain JL, Billard V, Servin F, Montravers P
Effectiveness of anaesthesia ventilator use for mechanical ventilation in critically ill patients during the COVID-19 pandemic.
British Journal of Anaesthesia 2021, 127, e35-e37.

Ben M'Barek I, Landraud L, Desfrere L, Sallah K, Couffignal C, Schneider M, Mandelbrot L
Contribution of vaginal culture to predict early onset neonatal infection in preterm prelabor rupture of membranes.
European Journal of Obstetrics, Gynecology, and Reproductive Biology 2021, 261, 78-84.

Tsatsaris V, Mariaggi AA, Launay O, Couffignal C, Rousseau J, Ancel PY, Marcault E, Ville Y, Cordier AG, Vivanti A, Carrara J, Luton D, Dommergues M, Borie C, Kayem G, Alessandrini V, Lecomte L, Meritet JF, Leruez-Ville M, Goffinet F, Dubois C, Picone O, Vauloup Fellous C
SARS-COV-2 IgG antibody response in pregnant women at delivery.
Journal of Gynecology Obstetrics and Human Reproduction 2021, 50, 102041.

Sigaut S, Couffignal C, Esposito-Farèse M, Degos V, Molliex S, Boddaert J, Raynaud-Simon A, Durand-Zaleski I, Marcault E, Jacota M, Dahmani S, Paugam-Burtz C, Weiss E
Melatonin for prevention of postoperative delirium after lower limb fracture surgery in elderly patients (DELIRLESS): study protocol for a multicentre randomised controlled trial.
BMJ open 2021, 11, e053908.

Deruelle P, Couffignal C, Sibiude J, Vivanti AJ, Anselem O, Luton D, Benachi A, Mandelbrot L, Vauloup-Fellous C, Cordier AG, Picone O
Prenatal care providers' perceptions of the SARS-Cov-2 vaccine for themselves and for pregnant women.
PloS One 2021, 16, e0256080.

2020

Gouel-Cheron A, Couffignal C, Elmaleh Y, Kantor E, Montravers P
Preliminary observations of anaesthesia ventilators use for prolonged mechanical ventilation in intensive care unit patients during the COVID-19 pandemic.
Anaesthesia, Critical Care & Pain Medicine 2020, 39, 371-372.

Philippot Q, Debray MP, Bun R, Frija-Masson J, Bunel V, Morer L, Roux A, Picard C, Jebrak G, Dauriat G, Castier Y, Cazes A, Mal H, Taupin JL, Couffignal C, Brugière O
Use of CT-SCAN score and volume measures to early identify restrictive allograft syndrome in single lung transplant recipients.
The Journal of Heart and Lung Transplantation: The Official Publication of the International Society for Heart Transplantation 2020, 39, 125-133.

Wauquier N, Couffignal C, Manchon P, Smith E, Lungay V, Coomber M, Weisenfluh L, Bangura J, Khan SH, Jambai A, Gbakima A, Yun N, Paessler S, Schoepp R, Morse SS, Gonzalez JP, Fair J, Mentré F, Vieillard V
High heart rate at admission as a predictive factor of mortality in hospitalized patients with Lassa fever: An observational cohort study in Sierra Leone.
The Journal of Infection 2020, 80, 671-693.

Egloff C, Sibiude J, Couffignal C, Mandelbrot L, Picone O
Causes and consequences of fever during pregnancy: A retrospective study in a gynaecological emergency department.
Journal of Gynecology Obstetrics and Human Reproduction 2020, 49, 101899.

Couffignal C, Papot E, Etienne A, Legac S, Laouénan C, Beres D, Blum L, Khuong-Josses MA, Lepretre A, Papazian P, Yazdanpanah Y, Bouvet E
Treatment as prevention (TasP) and perceived sexual changes in behavior among HIV-positive persons: a French survey in infectious diseases departments in Paris.
AIDS care 2020, 32, 811-817.

Couffignal C, Kolta S, Flamant M, Cazanave C, Haymann JP, Mentré F, Duval X, Leport C, Raffi F, ACACSG
Nevirapine Use Is Associated with Higher Bone Mineral Density in HIV-1 Positive Subjects on Long-Term Antiretroviral Therapy.
AIDS research and human retroviruses 2020, 36, 399-405.

Couffignal C, Amour J, Ait-Hamou N, Cholley B, Fellahi JL, Duval X, Costa De Beauregard Y, Nataf P, Dilly MP, Provenchère S, Montravers P, Mentré F, Longrois D
Timing of β-Blocker Reintroduction and the Occurrence of Postoperative Atrial Fibrillation after Cardiac Surgery: A Prospective Cohort Study.
Anesthesiology 2020, 132, 267-279.

Dupin C, Belhadi D, Guilleminault L, Gamez AS, Berger P, De Blay F, Bonniaud P, Leroyer C, Mahay G, Girodet PO, Raherison C, Fry S, Le Bourdellès G, Proust A, Rosencher L, Garcia G, Bourdin A, Chenivesse C, Didier A, Couffignal C, Taillé C
Effectiveness and safety of dupilumab for the treatment of severe asthma in a real-life French multi-centre adult cohort.
Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology 2020, 50, 789-798.

2019

Couffignal C, Bertrand J, Sportiche S, Jarroir M, El Balkhi S, Djebrani-Oussedik N, Poupon J, Declèves X, Mentré F, Bellivier F
Population pharmacokinetic modeling of sustained release lithium in the serum, erythrocytes and urine of patients with bipolar disorder.
European Journal of Clinical Pharmacology 2019, 75, 519-528.

Bastard JP, Couffignal C, Fellahi S, Bard JM, Mentre F, Salmon D, Katlama C, Raffi F, Leport C, Capeau J, ACACCsg
Diabetes and dyslipidaemia are associated with oxidative stress independently of inflammation in long-term antiretroviral-treated HIV-infected patients.
Diabetes & Metabolism 2019, 45, 573-581.

Bellocq A, Gaspard W, Couffignal C, Vigan M, Guerder A, Ambard J, Caruana S, Similowski T, Garcia G, Taillé C
Outpatient pulmonary rehabilitation for severe asthma with fixed airway obstruction: Comparison with COPD.
The Journal of Asthma: Official Journal of the Association for the Care of Asthma 2019, 1-9.

2018

Pellat A, Dreyer C, Couffignal C, Walter T, Lombard-Bohas C, Niccoli P, Seitz JF, Hentic O, André T, Coriat R, Faivre S, Zappa M, Ruszniewski P, Pote N, Couvelard A, Raymond E
Clinical and Biomarker Evaluations of Sunitinib in Patients with Grade 3 Digestive Neuroendocrine Neoplasms.
Neuroendocrinology 2018, 107, 24-31.

2017

Grall N, Lazarevic V, Gaia N, Couffignal C, Laouenan C, Ilic-Habensus E, Wieder I, Plesiat P, Angebault C, Bougnoux ME, Armand-Lefevre L, Andremont A, Duval X, Schrenzel J
Unexpected persistence of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the faecal microbiota of hospitalised patients treated with imipenem.
Int J Antimicrob Agents 2017, 50, 81-87.

Clermont O, Couffignal C, Blanco J, Mentre F, Picard B, Denamur E
Two levels of specialization in bacteraemic Escherichia coli strains revealed by their comparison with commensal strains.
Epidemiol Infect 2017, 145, 872-882.

Massot M, Couffignal C, Clermont O, D'Humières C, Chatel J, Plault N, Andremont A, Caron A, Mentré F, Denamur E
Day-to-Day Dynamics of Commensal Escherichia coli in Zimbabwean Cows Evidence Temporal Fluctuations within a Host-Specific Population Structure.
Applied and Environmental Microbiology 2017, 83, e00659-17.

Tournu G, Abramowitz L, Couffignal C, Juguet F, Sénéjoux A, Berger S, Wiart AL, Bernard M, Provost F, Pillant-Le Moult H, Bouchard D, Aubert JP, Gsg, MPsg
Prevalence of anal symptoms in general practice: a prospective study.
BMC family practice 2017, 18, 78.

2016

Lasocki S, Piednoir P, Couffignal C, Rineau E, Dufour G, Lefebvre T, Puy H, Duval X, Driss F, Schilte C
Does IV Iron Induce Plasma Oxidative Stress in Critically Ill Patients? A Comparison With Healthy Volunteers.
Crit Care Med 2016, 44, 521-30.

Massot M, Daubie AS, Clermont O, Jaureguy F, Couffignal C, Dahbi G, Mora A, Blanco J, Branger C, Mentre F, Eddi A, Picard B, Denamur E, The Coliville G
Phylogenetic, virulence and antibiotic resistance characteristics of commensal strain populations of Escherichia coli from community subjects in the Paris area in 2010 and evolution over 30 years.
Microbiology 2016, 162, 642-50.

2015

Burdet C, Pajot O, Couffignal C, Armand-Lefèvre L, Foucrier A, Laouénan C, Wolff M, Massias L, Mentré F
Population pharmacokinetics of single-dose amikacin in critically ill patients with suspected ventilator-associated pneumonia.
European Journal of Clinical Pharmacology 2015, 71, 75–83.

Couffignal C, Desgrandchamps F, Mongiat-Artus P, Ravery V, Ouzaid I, Roupret M, Phe V, Ciofu C, Tubach F, Mentre F, Cussenot O, Grandchamp B
The Diagnostic and Prognostic Performance of Urinary FGFR3 Mutation Analysis in Bladder Cancer Surveillance: A Prospective Multicenter Study.
Urology 2015, 86, 1185-1190.

Soubirou JF, Rossi B, Couffignal C, Ruppé E, Chau F, Massias L, Lepeule R, Mentre F, Fantin B
Activity of temocillin in a murine model of urinary tract infection due to Escherichia coli producing or not producing the ESBL CTX-M-15.
The Journal of Antimicrobial Chemotherapy 2015, 70, 1466–1472.

Pajot O, Burdet C, Couffignal C, Massias L, Armand-Lefevre L, Foucrier A, Da Silva D, Lasocki S, Laouénan C, Mentec H, Mentré F, Wolff M
Impact of imipenem and amikacin pharmacokinetic/pharmacodynamic parameters on microbiological outcome of Gram-negative bacilli ventilator-associated pneumonia.
The Journal of Antimicrobial Chemotherapy 2015, 70, 1487–1494.

Bastard JP, Fellahi S, Couffignal C, Raffi F, Gras G, Hardel L, Sobel A, Leport C, Fardet L, Capeau J, ACACCSG
Increased systemic immune activation and inflammatory profile of long-term HIV-infected ART-controlled patients is related to personal factors, but not to markers of HIV infection severity.
The Journal of Antimicrobial Chemotherapy 2015, 70, 1816-1824.

2014

Couffignal C, Pajot O, Laouénan C, Burdet C, Foucrier A, Wolff M, Armand-Lefevre L, Mentré F, Massias L
Population pharmacokinetics of imipenem in critically ill patients with suspected ventilator-associated pneumonia and evaluation of dosage regimens.
British Journal of Clinical Pharmacology 2014, 78, 1022–1034.

2013

Escoubet B, Couffignal C, Laisy JP, Mangin L, Chillon S, Laouénan C, Serfaty JM, Jeunemaitre X, Mentré F, Zennaro MC
Cardiovascular effects of aldosterone: insight from adult carriers of mineralocorticoid receptor mutations.
Circulation. Cardiovascular Genetics 2013, 6, 381–390.