Members

  First name: Jérémy
  Last name: Seurat
  Position: Postdoc
  Email: jeremy.seurat
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inserm.fr

Research interest


Pharmacometrics, Antimicrobials (Bacteriophages, antibiotics), Optimal design.

Education

Degree

PharmD, PhD in biostatistics and biomathematics

Exhaustive list of publications

2024


Zborowsky S, Seurat J, Balacheff Q, Minh CNN, Titécat M, Evrard E, Rodriguez-Gonzalez RA, Marchi J, Weitz JS, Debarbieux L
Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy.
bioRxiv: The Preprint Server for Biology 2024, 2024.01.16.575879.

2023


Goulenok T, Seurat J, Selle AdL, Jullien V, Leflon-Guibout V, Grall N, Lescure FX, Lepeule R, Bertrand J, Fantin B, Burdet C, Lefort A
Pharmacokinetic interaction between rifampicin and clindamycin in staphylococcal osteoarticular infections.
International Journal of Antimicrobial Agents 2023, 62, 106885.

Fayette L, Leroux R, Mentré F, Seurat J
Robust and Adaptive Two-stage Designs in Nonlinear Mixed Effect Models.
The AAPS journal 2023, 25, 71.

2022


Delattre R, Seurat J, Haddad F, Nguyen TT, Gaborieau B, Kane R, Dufour N, Ricard JD, Guedj J, Debarbieux L
Combination of in vivo phage therapy data with in silico model highlights key parameters for pneumonia treatment efficacy.
Cell Reports 2022, 39, 110825.

2021


Seurat J, Tang Y, Mentré F, Nguyen TT
Finding optimal design in nonlinear mixed effect models using multiplicative algorithms.
Computer Methods and Programs in Biomedicine 2021, 207, 106126.

2020


Seurat J, Girard P, Goteti K, Mentré F
Comparison of Various Phase I Combination Therapy Designs in Oncology for Evaluation of Early Tumor Shrinkage Using Simulations.
CPT: pharmacometrics & systems pharmacology 2020, 9, 686-694.

Seurat J, Nguyen TT, Mentré F
Robust designs accounting for model uncertainty in longitudinal studies with binary outcomes.
Statistical Methods in Medical Research 2020, 29, 934-952.