First name: Marion
  Last name: Kerioui
  Function: Postdoctoral researcher
  Position: Postdoctoral researcher
  Email: marion.kerioui

Research interest

The objective of my PhD was to develop multilevel nonlinear joint models of target lesions dynamics and survival in metastatic cancer patients.   Bayesian inference; Joint model; Nonlinear mixed-effects model; Survival analysis; Oncology; Hierarchical models.



2018: MSc equivalent in Statistics (engineering degree) – National School for Statistics and information Analysis (ENSAI)

2018: MSc in theoretical Mathematics – Rennes 1 University

Academic positions

2018 – 2022: PhD in biostatistics and biomathematics – Paris Cité University
supervised by Jérémie Guedj (INSERM IAME U1137) and Solène Desmée (INSERM SPHERE U1246)

List of the main publications

Exhaustive list of publications


Kerioui M, Bertrand J, Desmée S, Le Tourneau C, Mercier F, Bruno R, Guedj J
Assessing the Increased Variability in Individual Lesion Kinetics During Immunotherapy: Does It Exist, and Does It Matter?.
JCO precision oncology 2023, 7, e2200368.


Kerioui M, Desmée S, Mercier F, Lin A, Wu B, Jin JY, Shen X, Le Tourneau C, Bruno R, Guedj J
Assessing the impact of organ-specific lesion dynamics on survival in patients with recurrent urothelial carcinoma treated with atezolizumab or chemotherapy.
ESMO open 2022, 7, 100346.

Kerioui M, Bertrand J, Bruno R, Mercier F, Guedj J, Desmée S
Modelling the association between biomarkers and clinical outcome: An introduction to nonlinear joint models.
British Journal of Clinical Pharmacology 2022, 88, 1452-1463.


Marc A, Kerioui M, Blanquart F, Bertrand J, Mitjà O, Corbacho-Monné M, Marks M, Guedj J
Quantifying the relationship between SARS-CoV-2 viral load and infectiousness.
eLife 2021, 10, e69302.


Kerioui M, Mercier F, Bertrand J, Tardivon C, Bruno R, Guedj J, Desmée S
Bayesian inference using Hamiltonian Monte-Carlo algorithm for nonlinear joint modeling in the context of cancer immunotherapy.
Statistics in Medicine 2020, 39, 4853-4868.

Mercier F, Kerioui M, Desmée S, Guedj J, Krieter O, Bruno R
Longitudinal analysis of organ-specific tumor lesion sizes in metastatic colorectal cancer patients receiving first line standard chemotherapy in combination with anti-angiogenic treatment.
Journal of Pharmacokinetics and Pharmacodynamics 2020, 47, 613-625.


Tardivon C, Desmée S, Kerioui M, Bruno R, Wu B, Mentré F, Mercier F, Guedj J
Association Between Tumor Size Kinetics and Survival in Patients With Urothelial Carcinoma Treated With Atezolizumab: Implication for Patient Follow-Up.
Clinical Pharmacology and Therapeutics 2019, 106, 810-820.