Members
 | First name: Sophie Last name: Magréault Function: Pharmacology Position: Assistante Hospitalo-Universitaire Email: sophie.magreaultinserm.fr |
Research interest
Pharmacokinetics-pharmacodynamics of anti-infectives in specific populations and pathologies, with a focus on antibiotic tissue diffusion and drug-drug interactions.
Education
Degree
2019 : Ph. D. in Pharmacokinetics, University of Poitiers
2017 : Pharm. D. and specialisation in medical biology (Pharmacology and Toxicology), Paris Descartes University
2011: Second cycle of pharmaceutical studies, University of Poitiers
2017 : Pharm. D. and specialisation in medical biology (Pharmacology and Toxicology), Paris Descartes University
2011: Second cycle of pharmaceutical studies, University of Poitiers
Academic positions
2021 – present : Assistant in Pharmacology, Medical School, Sorbonne Paris Nord University
2011-2017 : Resident in medical biology, Paris Descartes University
2011-2017 : Resident in medical biology, Paris Descartes University
Research training (post doctoral)
2020 – present: Researcher at the INSERM unit UMR 1137, IAME team BIPID, University of Paris
Exhaustive list of publications
2023
Magréault S, Charbit J, Berkane N, Jaureguy F, Carbonnelle E, Cosson E, Jullien V, Bihan H
Usefulness of Therapeutic Drug Monitoring to Manage Clindamycin-Rifampicin Interaction in a Patient with Diabetic Foot Osteomyelitis.
Therapeutic Drug Monitoring 2023, 45, 703-706.
Facchin A, Benyoub N, Elie V, Magreault S, Jacqz-Aigrain E
Limited Sampling Strategies to Predict Ganciclovir Exposure after Valganciclovir Administration and to Reduce Monitoring Constraints in Renal Transplant Children.
Antimicrobial Agents and Chemotherapy 2023, 67, e0159722.
2022
Magréault S, Jaureguy F, Zahar JR, Méchaï F, Toinon D, Cohen Y, Carbonnelle E, Jullien V
Automated HPLC-MS/MS assay for the simultaneous determination of ten plasma antibiotic concentrations.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences 2022, 1211, 123496.
Imbard A, Toumazi A, Magréault S, Garcia-Segarra N, Schlemmer D, Kaguelidou F, Perronneau I, Haignere J, de Baulny HO, Kuster A, Feillet F, Alberti C, Guilmin-Crépon S, Benoist JF, Schiff M
Efficacy and pharmacokinetics of betaine in CBS and cblC deficiencies: a cross-over randomized controlled trial.
Orphanet Journal of Rare Diseases 2022, 17, 417.
Mimram L, Magréault S, Kerroumi Y, Salmon D, Kably B, Marmor S, Jannot AS, Jullien V, Zeller V
Population Pharmacokinetics of Orally Administered Clindamycin to Treat Prosthetic Joint Infections: A Prospective Study.
Antibiotics (Basel, Switzerland) 2022, 11, 1462.
Magréault S, Jauréguy F, Carbonnelle E, Zahar JR
When and How to Use MIC in Clinical Practice?.
Antibiotics (Basel, Switzerland) 2022, 11, 1748.
2021
Magréault S, Roy C, Launay M, Sermet-Gaudelus I, Jullien V
Pharmacokinetic and Pharmacodynamic Optimization of Antibiotic Therapy in Cystic Fibrosis Patients: Current Evidences, Gaps in Knowledge and Future Directions.
Clinical Pharmacokinetics 2021, 60, 409-445.
Zeller V, Magreault S, Heym B, Salmon D, Kitzis MD, Billaud E, Marmor S, Jannot AS, Salomon L, Jullien V
Influence of the clindamycin administration route on the magnitude of clindamycin-rifampicin interaction: a prospective pharmacokinetic study.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, 27, 1857.e1-1857.e7.
2020
Magréault S, Mankikian J, Marchand S, Diot P, Couet W, Flament T, Grégoire N
Pharmacokinetics of colistin after nebulization or intravenous administration of colistin methanesulphonate (Colimycin®) to cystic fibrosis patients.
Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society 2020, 19, 421-426.
2019
Magréault S, Leroux S, Touati J, Storme T, Jacqz-Aigrain E
UPLC/MS/MS assay for the simultaneous determination of seven antibiotics in human serum-Application to pediatric studies.
Journal of Pharmaceutical and Biomedical Analysis 2019, 174, 256-262.
Facchin A, Elie V, Benyoub N, Magreault S, Maisin A, Storme T, Zhao W, Deschenes G, Jacqz-Aigrain E
Population pharmacokinetics of ganciclovir after valganciclovir in renal transplant children.
Antimicrobial Agents and Chemotherapy 2019, 63, e01192-19, AAC.01192-19.
2018
Magréault S, Petyt C, Senneville E, Fron D, Nectoux E, Loiez C, Marchand S, Grégoire N, Couet W
Pharmacokinetics of colistin in a 8-year-old child with acute bone infection.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 1025-1026.
Leroux S, Elie V, Zhao W, Magreault S, Jacqz-Aigrain E
Principles and applications of pharmacometrics in drug evaluation in children.
Therapie 2018, 73, 165-170.
Magréault S, Grégoire N, Marchand S, Couet W
Colistin Pharmacokinetics in Pediatrics.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018, 66, 809.
2017
Grégoire N, Aranzana-Climent V, Magréault S, Marchand S, Couet W
Clinical Pharmacokinetics and Pharmacodynamics of Colistin.
Clinical Pharmacokinetics 2017, 56, 1441-1460.
Ferry T, Desmarchelier R, Magréault S, Valour F, Lyon BJI Study group
Gentamicin-vancomycin-colistin local antibiotherapy in a cement spacer in a 54-year-old haemophilic patient with relapsing plurimicrobial severe prosthetic joint infection.
BMJ case reports 2017, 2017, bcr2017221743, bcr-2017-221743.
