Members

  First name: Bruno
  Last name: Mourvillier
  Function: Researcher
  Position: MD
  Email: bruno.mourvillier
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inserm.fr

Research interest



Education

Degree

MD

Exhaustive list of publications

2021


Ader F, Peiffer-Smadja N, Poissy J, Bouscambert-Duchamp M, Belhadi D, Diallo A, Delmas C, Saillard J, Dechanet A, Mercier N, Dupont A, Alfaiate T, Lescure FX, Raffi F, Goehringer F, Kimmoun A, Jaureguiberry S, Reignier J, Nseir S, Danion F, Clere-Jehl R, Bouiller K, Navellou JC, Tolsma V, Cabié A, Dubost C, Courjon J, Leroy S, Mootien J, Gaci R, Mourvillier B, Faure E, Pourcher V, Gallien S, Launay O, Lacombe K, Lanoix JP, Makinson A, Martin-Blondel G, Bouadma L, Botelho-Nevers E, Gagneux-Brunon A, Epaulard O, Piroth L, Wallet F, Richard JC, Reuter J, Staub T, Lina B, Noret M, Andrejak C, Lê MP, Peytavin G, Hites M, Costagliola D, Yazdanpanah Y, Burdet C, Mentré F, Dsg
An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with COVID-19.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, S1198-743X(21)00259-7.

Dupuis C, Bouadma L, de Montmollin E, Goldgran-Toledano D, Schwebel C, Reignier J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Grapin K, Laurent V, Buetti N, Gainnier M, Souweine B, Timsit JF
Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia.
Critical Care Explorations 2021, 3, e0329.

Papin G, Bailly S, Dupuis C, Ruckly S, Gainnier M, Argaud L, Azoulay E, Adrie C, Souweine B, Goldgran-Toledano D, Marcotte G, Gros A, Reignier J, Mourvillier B, Forel JM, Sonneville R, Dumenil AS, Darmon M, Garrouste-Orgeas M, Schwebel C, Timsit JF, Osg
Clinical and biological clusters of sepsis patients using hierarchical clustering.
PloS One 2021, 16, e0252793.

Dupuis C, de Montmollin E, Buetti N, Goldgran-Toledano D, Reignier J, Schwebel C, Domitile J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Laurent V, Gainnier M, Souweine B, Timsit JF, Orn
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network.
PloS One 2021, 16, e0255644.

Ursino M, Dupuis C, Buetti N, de Montmollin E, Bouadma L, Golgran-Toledano D, Ruckly S, Neuville M, Cohen Y, Mourvillier B, Souweine B, Gainnier M, Laurent V, Terzi N, Shiami S, Reignier J, Alberti C, Timsit JF, On Behalf Of The Outcomerea Study Group n
Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients.
Journal of Clinical Medicine 2021, 10,

2020


Andremont O, Armand-Lefevre L, Dupuis C, de Montmollin E, Ruckly S, Lucet JC, Smonig R, Magalhaes E, Ruppé E, Mourvillier B, Lebut J, Lermuzeaux M, Sonneville R, Bouadma L, Timsit JF, Cnc
Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.
Intensive Care Medicine 2020, 46, 1232-1242.

Tubiana S, Varon E, Biron C, Ploy MC, Mourvillier B, Taha MK, Revest M, Poyart C, Martin-Blondel G, Lecuit M, Cua E, Pasquet B, Preau M, Hoen B, Duval X, Csg
Community-acquired bacterial meningitis in adults: in-hospital prognosis, long-term disability and determinants of outcome in a multicentre prospective cohort.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, 26, 1192-1200.

Bailly S, Galerneau LM, Ruckly S, Seiller A, Terzi N, Schwebel C, Dupuis C, Tamisier R, Mourvillier B, Pepin JL, Timsit JF
Impact of obstructive sleep apnea on the obesity paradox in critically ill patients.
Journal of Critical Care 2020, 56, 120-124.

Ibn Saied W, Merceron S, Schwebel C, Le Monnier A, Oziel J, Garrouste-Orgeas M, Marcotte G, Ruckly S, Souweine B, Darmon M, Bouadma L, de Montmollin E, Mourvillier B, Reignier J, Papazian L, Siami S, Azoulay E, Bédos JP, Timsit JF
Ventilator-associated pneumonia due to Stenotrophomonas maltophilia: Risk factors and outcome.
The Journal of Infection 2020, 80, 279-285.

San C, Lê MP, Matheron S, Mourvillier B, Caseris M, Timsit JF, Wolff M, Yazdanpanah Y, Descamps D, Peytavin G
Management of oral antiretroviral administration in patients with swallowing disorders or with an enteral feeding tube.
Medecine Et Maladies Infectieuses 2020, 50, 537-544.

Bailly S, Gautier-Veyret E, Lê MP, Bouadma L, Andremont O, Neuville M, Mourvillier B, Sonneville R, Magalhaes E, Lebut J, Radjou A, Smonig R, Wolff M, Massias L, Dupuis C, Timsit JF
Impact of Loading Dose of Caspofungin in Pharmacokinetic-Pharmacodynamic Target Attainment for Severe Candidiasis Infections in Patients in Intensive Care Units: the CASPOLOAD Study.
Antimicrobial Agents and Chemotherapy 2020, 64, e01545-20.

Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.

Dupuis C, Bouadma L, Ruckly S, Perozziello A, Van-Gysel D, Mageau A, Mourvillier B, de Montmollin E, Bailly S, Papin G, Sinnah F, Vinclair C, Abid S, Sonneville R, Timsit JF
Sepsis and septic shock in France: incidences, outcomes and costs of care.
Annals of Intensive Care 2020, 10, 145.

2019


Ibn Saied W, Mourvillier B, Cohen Y, Ruckly S, Reignier J, Marcotte G, Siami S, Bouadma L, Darmon M, de Montmollin E, Argaud L, Kallel H, Garrouste-Orgeas M, Soufir L, Schwebel C, Souweine B, Glodgran-Toledano D, Papazian L, Timsit JF
A Comparison of the Mortality Risk Associated With Ventilator-Acquired Bacterial Pneumonia and Nonventilator ICU-Acquired Bacterial Pneumonia*:.
Critical Care Medicine 2019, 47, 345-352.

Morvan AC, Garrouste-Orgeas M, Ruckly S, Forel JM, Argaud L, Rimmelé T, Bedos JP, Azoulay E, Dupuis C, Mourvillier B, Schwebel C, Timsit JF
Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care—an analysis of the OUTCOMEREA database.
Critical Care 2019, 23, 307.

Pons S, Sonneville R, Bouadma L, Styfalova L, Ruckly S, Neuville M, Radjou A, Lebut J, Dilly MP, Mourvillier B, Dorent R, Nataf P, Wolff M, Timsit JF
Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation.
Annals of Intensive Care 2019, 9, 17.

Smonig R, Magalhaes E, Bouadma L, Andremont O, de Montmollin E, Essardy F, Mourvillier B, Lebut J, Dupuis C, Neuville M, Lermuzeaux M, Timsit JF, Sonneville R
Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study.
Annals of Intensive Care 2019, 9, 120.

2018


Barbier F, Bailly S, Schwebel C, Papazian L, Azoulay É, Kallel H, Siami S, Argaud L, Marcotte G, Misset B, Reignier J, Darmon M, Zahar JR, Goldgran-Toledano D, de Montmollin É, Souweine B, Mourvillier B, Timsit JF, OSG
Infection-related ventilator-associated complications in ICU patients colonised with extended-spectrum β-lactamase-producing Enterobacteriaceae.
Intensive Care Medicine 2018

Azoulay E, Lemiale V, Mourvillier B, Garrouste-Orgeas M, Schwebel C, Ruckly S, Argaud L, Cohen Y, Souweine B, Papazian L, Reignier J, Marcotte G, Siami S, Kallel H, Darmon M, Timsit JF, OSG
Management and outcomes of acute respiratory distress syndrome patients with and without comorbid conditions.
Intensive Care Medicine 2018

Bleibtreu A, Jaureguiberry S, Houhou N, Boutolleau D, Guillot H, Vallois D, Lucet JC, Robert J, Mourvillier B, Delemazure J, Jaspard M, Lescure FX, Rioux C, Caumes E, Yazdanapanah Y
Clinical management of respiratory syndrome in patients hospitalized for suspected Middle East respiratory syndrome coronavirus infection in the Paris area from 2013 to 2016.
BMC infectious diseases 2018, 18, 331.

Cantier M, Morisot A, Guérot E, Megarbane B, Razazi K, Contou D, Mariotte E, Canet E, De Montmollin E, Dubée V, Boulet E, Gaudry S, Voiriot G, Mayaux J, Pène F, Neuville M, Mourvillier B, Ruckly S, Bouadma L, Wolff M, Timsit JF, Sonneville R, Esg
Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study.
Critical Care (London, England) 2018, 22, 210.

2017


Sonneville R, de Montmollin E, Poujade J, Garrouste-Orgeas M, Souweine B, Darmon M, Mariotte E, Argaud L, Barbier F, Goldgran-Toledano D, Marcotte G, Dumenil AS, Jamali S, Lacave G, Ruckly S, Mourvillier B, Timsit JF
Potentially modifiable factors contributing to sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1075-1084.

Adrie C, Garrouste-Orgeas M, Ibn Essaied W, Schwebel C, Darmon M, Mourvillier B, Ruckly S, Dumenil AS, Kallel H, Argaud L, Marcotte G, Barbier F, Laurent V, Goldgran-Toledano D, Clec'h C, Azoulay E, Souweine B, Timsit JF, OSG
Attributable mortality of ICU-acquired bloodstream infections: Impact of the source, causative micro-organism, resistance profile and antimicrobial therapy.
The Journal of Infection 2017, 74, 131-141.

Terzi N, Darmon M, Reignier J, Ruckly S, Garrouste-Orgeas M, Lautrette A, Azoulay E, Mourvillier B, Argaud L, Papazian L, Gainnier M, Goldgran-Toledano D, Jamali S, Dumenil AS, Schwebel C, Timsit JF, Osg
Initial nutritional management during noninvasive ventilation and outcomes: a retrospective cohort study.
Critical Care (London, England) 2017, 21, 293.

Neuville M, El-Helali N, Magalhaes E, Radjou A, Smonig R, Soubirou JF, Voiriot G, Le Monnier A, Ruckly S, Bouadma L, Sonneville R, Timsit JF, Mourvillier B
Systematic overdosing of oxa- and cloxacillin in severe infections treated in ICU: risk factors and side effects.
Annals of Intensive Care 2017, 7, 34.

Neuville M, Mourvillier B, Bouadma L, Timsit JF
Bundle of care decreased ventilator-associated events-implications for ventilator-associated pneumonia prevention.
Journal of Thoracic Disease 2017, 9, 430-433.

2016


Gélisse E, Neuville M, de Montmollin E, Bouadma L, Mourvillier B, Timsit JF, Sonneville R
Extracorporeal membrane oxygenation (ECMO) does not impact on amikacin pharmacokinetics: a case-control study.
Intensive Care Medicine 2016, 42, 946-948.

Barbier F, Pommier C, Essaied W, Garrouste-Orgeas M, Schwebel C, Ruckly S, Dumenil AS, Lemiale V, Mourvillier B, Clec'h C, Darmon M, Laurent V, Marcotte G, Lucet JC, Souweine B, Zahar JR, Timsit JF, OSG
Colonization and infection with extended-spectrum β-lactamase-producing Enterobacteriaceae in ICU patients: what impact on outcomes and carbapenem exposure?.
The Journal of Antimicrobial Chemotherapy 2016, 71, 1088-1097.

Sonneville R, Mariotte E, Neuville M, Minaud S, Magalhaes E, Ruckly S, Cantier M, Voiriot G, Radjou A, Smonig R, Soubirou JF, Mourvillier B, Bouadma L, Wolff M, Timsit JF
Early-onset status epilepticus in patients with acute encephalitis.
Medicine 2016, 95, e4092.

Mourvillier B, Radjou A, Timsit JF
Subclavian site should be preferred for central venous access.
Evidence-Based Nursing 2016, 19, 126.

Voiriot G, Visseaux B, Cohen J, Nguyen LB, Neuville M, Morbieu C, Burdet C, Radjou A, Lescure FX, Smonig R, Armand-Lefevre L, Mourvillier B, Yazdanpanah Y, Soubirou JF, Ruckly S, Houhou-Fidouh N, Timsit JF
Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia.
Crit Care 2016, 20, 375.

2015


Lautrette A, Garrouste-Orgeas M, Bertrand PM, Goldgran-Toledano D, Jamali S, Laurent V, Argaud L, Schwebel C, Mourvillier B, Darmon M, Ruckly S, Dumenil AS, Lemiale V, Souweine B, Timsit JF, OSG
Respective impact of no escalation of treatment, withholding and withdrawal of life-sustaining treatment on ICU patients' prognosis: a multicenter study of the Outcomerea Research Group.
Intensive Care Medicine 2015, 41, 1763-1772.

Le Dorze M, Gault N, Foucrier A, Ruppé E, Mourvillier B, Woerther PL, Birgand G, Montravers P, Dilly MP, Tubach F, Andremont A, Timsit JF, Wolff M, Armand-Lefèvre L
Performance and impact of a rapid method combining mass spectrometry and direct antimicrobial susceptibility testing on treatment adequacy of patients with ventilator-associated pneumonia.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015, 21, 468.e1-6.

Sonneville R, Gault N, de Montmollin E, Klein IF, Mariotte E, Chemam S, Tubach F, Mourvillier B, Timsit JF, Wolff M, Bouadma L
Clinical spectrum and outcomes of patients with encephalitis requiring intensive care.
European Journal of Neurology: The Official Journal of the European Federation of Neurological Societies 2015, 22, 6-16, e1.

2014


de Montmollin E, Bouadma L, Gault N, Mourvillier B, Mariotte E, Chemam S, Massias L, Papy E, Tubach F, Wolff M, Sonneville R
Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen.
Intensive Care Medicine 2014, 40, 998-1005.

Wolff M, Mourvillier B, Sonneville R, Timsit JF
My paper 10 years later: infective endocarditis in the intensive care unit.
Intensive Care Medicine [MY PAPER 20 YEARS LATER] 2014, 40, 1843-1852.

Fassa AA, Mazighi M, Himbert D, Deschamps L, Ducrocq G, Cheong AP, Depoix JP, Dilly MP, Alkhoder S, Mourvillier B, Vahanian A
Successful endovascular stroke rescue with retrieval of an embolized calcium fragment after transcatheter aortic valve replacement.
Circulation. Cardiovascular Interventions 2014, 7, 125-126.

Timsit JF, Soubirou JF, Voiriot G, Chemam S, Neuville M, Mourvillier B, Sonneville R, Mariotte E, Bouadma L, Wolff M
Treatment of bloodstream infections in ICUs.
BMC infectious diseases 2014, 14, 489.

2013


Mourvillier B, Tubach F, van de Beek D, Garot D, Pichon N, Georges H, Lefevre LM, Bollaert PE, Boulain T, Luis D, Cariou A, Girardie P, Chelha R, Megarbane B, Delahaye A, Chalumeau-Lemoine L, Legriel S, Beuret P, Brivet F, Bruel C, Camou F, Chatellier D, Chillet P, Clair B, Constantin JM, Duguet A, Galliot R, Bayle F, Hyvernat H, Ouchenir K, Plantefeve G, Quenot JP, Richecoeur J, Schwebel C, Sirodot M, Esposito-Farèse M, Le Tulzo Y, Wolff M
Induced hypothermia in severe bacterial meningitis: a randomized clinical trial.
JAMA 2013, 310, 2174-2183.

Denneman L, Vial-Dupuy A, Gault N, Wolff M, van de Beek D, Mourvillier B
Repeated lumbar puncture in adults with pneumococcal meningitis: an observational study.
The Journal of Infection 2013, 67, 350-353.

Novy E, Sonneville R, Mazighi M, Klein IF, Mariotte E, Mourvillier B, Bouadma L, Wolff M
Neurological complications of infective endocarditis: new breakthroughs in diagnosis and management.
Medecine Et Maladies Infectieuses 2013, 43, 443-450.

Goulenok T, Klein I, Mazighi M, Messika-Zeitoun D, Alexandra JF, Mourvillier B, Laissy JP, Leport C, Iung B, Duval X, Isg
Infective endocarditis with symptomatic cerebral complications: contribution of cerebral magnetic resonance imaging.
Cerebrovascular Diseases (Basel, Switzerland) 2013, 35, 327-336.

Pham T, Combes A, Rozé H, Chevret S, Mercat A, Roch A, Mourvillier B, Ara-Somohano C, Bastien O, Zogheib E, Clavel M, Constan A, Marie Richard JC, Brun-Buisson C, Brochard L, RRN
Extracorporeal membrane oxygenation for pandemic influenza A(H1N1)-induced acute respiratory distress syndrome: a cohort study and propensity-matched analysis.
American Journal of Respiratory and Critical Care Medicine 2013, 187, 276-285.

Planquette B, Timsit JF, Misset BY, Schwebel C, Azoulay E, Adrie C, Vesin A, Jamali S, Zahar JR, Allaouchiche B, Souweine B, Darmon M, Dumenil AS, Goldgran-Toledano D, Mourvillier BH, Bédos JP, OSG
Pseudomonas aeruginosa ventilator-associated pneumonia. predictive factors of treatment failure.
American Journal of Respiratory and Critical Care Medicine 2013, 188, 69-76.

Annane D, Timsit JF, Megarbane B, Martin C, Misset B, Mourvillier B, Siami S, Chagnon JL, Constantin JM, Petitpas F, Souweine B, Amathieu R, Forceville X, Charpentier C, Tesnière A, Chastre J, Bohe J, Colin G, Cariou A, Renault A, Brun-Buisson C, Bellissant E, ATI
Recombinant human activated protein C for adults with septic shock: a randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2013, 187, 1091-1097.

2012


Wolff M, Mourvillier B
Linezolid for the treatment of nosocomial pneumonia due to methicillin-resistant Staphylococcus aureus.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012, 55, 160-161.

Iung B, Klein I, Mourvillier B, Olivot JM, Détaint D, Longuet P, Ruimy R, Fourchy D, Laurichesse JJ, Laissy JP, Escoubet B, Duval X, SG
Respective effects of early cerebral and abdominal magnetic resonance imaging on clinical decisions in infective endocarditis.
European Heart Journal Cardiovascular Imaging 2012, 13, 703-710.

Foucrier A, Woerther PL, Le Dorze M, Ruimy R, Laissy JP, Castier Y, Mourvillier B
Pulmonary sequestration syndrome diagnosed from a Nocardia infection.
American Journal of Respiratory and Critical Care Medicine 2012, 186, 288.

Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Lepape A, Vesin A, Arrault X, Schwebel C, Adrie C, Zahar JR, Ruckly S, Tournegros C, Lucet JC
Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults.
American Journal of Respiratory and Critical Care Medicine 2012, 186, 1272-1278.

Richard JCM, Pham T, Brun-Buisson C, Reignier J, Mercat A, Beduneau G, Régnier B, Mourvillier B, Guitton C, Castanier M, Combes A, Le Tulzo Y, Brochard L, Rsg
Interest of a simple on-line screening registry for measuring ICU burden related to an influenza pandemic.
Critical Care (London, England) 2012, 16, R118.

Sonneville R, Schmidt M, Messika J, Ait Hssain A, da Silva D, Klein IF, Bouadma L, Wolff M, Mourvillier B
Neurologic outcomes and adjunctive steroids in HIV patients with severe cerebral toxoplasmosis.
Neurology 2012, 79, 1762-1766.

Bouadma L, Barbier F, Biard L, Esposito-Farèse M, Le Corre B, Macrez A, Salomon L, Bonnal C, Zanker C, Najem C, Mourvillier B, Lucet JC, Régnier B, Wolff M, Tubach F, IASG
Personal decision-making criteria related to seasonal and pandemic A(H1N1) influenza-vaccination acceptance among French healthcare workers.
PloS One 2012, 7, e38646.

Legriel S, Schraub O, Azoulay E, Hantson P, Magalhaes E, Coquet I, Bretonniere C, Gilhodes O, Anguel N, Megarbane B, Benayoun L, Schnell D, Plantefeve G, Charpentier J, Argaud L, Mourvillier B, Galbois A, Chalumeau-Lemoine L, Rivoal M, Durand F, Geffroy A, Simon M, Stoclin A, Pallot JL, Arbelot C, Nyunga M, Lesieur O, Troché G, Bruneel F, Cordoliani YS, Bedos JP, Pico F, CIPRESSG(
Determinants of recovery from severe posterior reversible encephalopathy syndrome.
PloS One 2012, 7, e44534.