Members
First name: Etienne Last name: De Montmollin Function: Attending physician in a medical intensive care unit Position: Hospital practitioner, AP-HP Email: etienne.demontmollin aphp.fr |
Research interest
My main area of research is clinical epidemiology in the field of intensive care medicine, with a focus on infectious diseases and neurointensive care. In the field of neurointensive care, I have research interests in the epidemiology and management of patients with severe encephalitis and meningitis, and patients with severe stroke. In the field of infectious diseases, I focus on antibiotic therapy in septic shock patients and severe infectious complications of immunocompromised patients. I also study the epidemiology of socioeconomic deprivation in critically ill patients.
Education
Degree
2020: Ph.D. in clinical epidemiology, Paris Cité University
2011: M.D. in internal medicine, Paris Descartes University
2011: M.D. in internal medicine, Paris Descartes University
Academic positions
2011-2013: Chief resident in intensive care medicine, Paris Diderot University
List of the main publications
Sonneville R, de Montmollin E, Contou D, Ferrer R, Gurjar M, Klouche K, Sarton B, Demeret S, Bailly P, da Silva D, Escudier E, Le Guennec L, Chabanne R, Argaud L, Ben Hadj Salem O, Thyrault M, Frerou A, Louis G, De Pascale G, Horn J, Helbok R, Geri G, Bruneel F, Martin-Loeches I, Taccone FS, De Waele JJ, Ruckly S, Staiquly Q, Citerio G, Timsit JF, EURECA Investigator Study Group
Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study.
Intensive Care Medicine 2023, 49, 517-529.
Thy M, Timsit JF, de Montmollin E
Aminoglycosides for the Treatment of Severe Infection Due to Resistant Gram-Negative Pathogens.
Antibiotics (Basel, Switzerland) 2023, 12, 860.
de Montmollin E, Dupuis C, Jaquet P, Sarton B, Sazio C, Susset V, Conrad M, Argaud L, Demeret S, Tadié JM, Barbier F, Wolff M, Timsit JF, Visseaux B, Sonneville R, ENCEPHALITICA Study Group
Herpes Simplex Virus Encephalitis With Initial Negative Polymerase Chain Reaction in the Cerebrospinal Fluid: Prevalence, Associated Factors, and Clinical Impact.
Critical Care Medicine 2022, 50, e643-e648.
Rambaud T, de Montmollin E, Jaquet P, Gaudemer A, Mariotte E, Abid S, Para M, Cimadevilla C, Iung B, Duval X, Wolff M, Bouadma L, Timsit JF, Sonneville R
Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis.
Annals of Intensive Care 2022, 12, 119.
Timsit JF, Wicky PH, de Montmollin E
Treatment of Severe Infections Due to Metallo-Betalactamases Enterobacterales in Critically Ill Patients.
Antibiotics (Basel, Switzerland) 2022, 11, 144.
de Montmollin E, Peoc'h K, Marzouk M, Ruckly S, Wicky PH, Patrier J, Jaquet P, Sonneville R, Bouadma L, Timsit JF
Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS.
Antibiotics (Basel, Switzerland) 2022, 11, 1166.
de Montmollin E, Faille D, Andrieu V, Ajzenberg N, Timsit JF
Intensified thromboprophylaxis in COVID-19 critically ill patients: Is it enough?.
The Journal of Infection 2021
de Montmollin E, Timsit JF
How Antibiotics Stewardship Can Be Safely Implemented in Patients with Septic Shock?.
Seminars in Respiratory and Critical Care Medicine 2021, 42, 689-697.
de Montmollin E, Schwebel C, Dupuis C, Garrouste-Orgeas M, da Silva D, Azoulay E, Laurent V, Thiéry G, Grinea A, Marcotte G, Oziel J, Gainnier M, Siami S, Reignier J, Sztrymf B, Adrie C, Ruckly S, Sonneville R, Timsit JF
Life Support Limitations in Mechanically Ventilated Stroke Patients.
Critical Care Explorations 2021, 3, e0341.
Dupuis C, de Montmollin E, Buetti N, Goldgran-Toledano D, Reignier J, Schwebel C, Domitile J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Laurent V, Gainnier M, Souweine B, Timsit JF, OutcomeReaTM research network
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network.
PloS One 2021, 16, e0255644.
Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.
OUTCOMEREA Study Group, de Montmollin E, Terzi N, Dupuis C, Garrouste-Orgeas M, da Silva D, Darmon M, Laurent V, Thiéry G, Oziel J, Marcotte G, Gainnier M, Siami S, Sztrymf B, Adrie C, Reignier J, Ruckly S, Sonneville R, Timsit JF
One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study.
Annals of Intensive Care 2020, 10, 53.
Jaquet P, de Montmollin E, Dupuis C, Sazio C, Conrad M, Susset V, Demeret S, Tadie JM, Argaud L, Barbier F, Sarton B, Chabane R, Daubin D, Brulé N, Lerolle N, Alves M, Da Silva D, Kalioubi AE, Silva S, Bailly P, Wolff M, Bouadma L, Timsit JF, Sonneville R, ENCEPHALITICA study group
Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study.
Intensive Care Medicine 2019, 45, 1103-1111.
de Montmollin E, Ruckly S, Schwebel C, Philippart F, Adrie C, Mariotte E, Marcotte G, Cohen Y, Sztrymf B, da Silva D, Bruneel F, Gainnier M, Garrouste-Orgeas M, Sonneville R, Timsit JF, OUTCOMEREA Study Group
Pneumonia in acute ischemic stroke patients requiring invasive ventilation: Impact on short and long-term outcomes.
The Journal of Infection 2019, 79, 220-227.
Sonneville R, de Montmollin E, Poujade J, Garrouste-Orgeas M, Souweine B, Darmon M, Mariotte E, Argaud L, Barbier F, Goldgran-Toledano D, Marcotte G, Dumenil AS, Jamali S, Lacave G, Ruckly S, Mourvillier B, Timsit JF
Potentially modifiable factors contributing to sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1075-1084.
de Montmollin E, Demeret S, Brulé N, Conrad M, Dailler F, Lerolle N, Navellou JC, Schwebel C, Alves M, Cour M, Engrand N, Tonnelier JM, Maury E, Ruckly S, Picard G, Rogemond V, Magalhaes É, Sharshar T, Timsit JF, Honnorat J, Sonneville R, ENCEPHALITICA Study Group ‡
Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.
American Journal of Respiratory and Critical Care Medicine 2017, 195, 491-499.
de Montmollin E, Bouadma L, Gault N, Mourvillier B, Mariotte E, Chemam S, Massias L, Papy E, Tubach F, Wolff M, Sonneville R
Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen.
Intensive Care Medicine 2014, 40, 998-1005.
de Montmollin E, Tandjaoui-Lambiotte Y, Legrand M, Lambert J, Mokart D, Kouatchet A, Lemiale V, Pène F, Bruneel F, Vincent F, Mayaux J, Chevret S, Azoulay E
Outcomes in critically ill cancer patients with septic shock of pulmonary origin.
Shock (Augusta, Ga.) 2013, 39, 250-254.
Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study.
Intensive Care Medicine 2023, 49, 517-529.
Thy M, Timsit JF, de Montmollin E
Aminoglycosides for the Treatment of Severe Infection Due to Resistant Gram-Negative Pathogens.
Antibiotics (Basel, Switzerland) 2023, 12, 860.
de Montmollin E, Dupuis C, Jaquet P, Sarton B, Sazio C, Susset V, Conrad M, Argaud L, Demeret S, Tadié JM, Barbier F, Wolff M, Timsit JF, Visseaux B, Sonneville R, ENCEPHALITICA Study Group
Herpes Simplex Virus Encephalitis With Initial Negative Polymerase Chain Reaction in the Cerebrospinal Fluid: Prevalence, Associated Factors, and Clinical Impact.
Critical Care Medicine 2022, 50, e643-e648.
Rambaud T, de Montmollin E, Jaquet P, Gaudemer A, Mariotte E, Abid S, Para M, Cimadevilla C, Iung B, Duval X, Wolff M, Bouadma L, Timsit JF, Sonneville R
Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis.
Annals of Intensive Care 2022, 12, 119.
Timsit JF, Wicky PH, de Montmollin E
Treatment of Severe Infections Due to Metallo-Betalactamases Enterobacterales in Critically Ill Patients.
Antibiotics (Basel, Switzerland) 2022, 11, 144.
de Montmollin E, Peoc'h K, Marzouk M, Ruckly S, Wicky PH, Patrier J, Jaquet P, Sonneville R, Bouadma L, Timsit JF
Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS.
Antibiotics (Basel, Switzerland) 2022, 11, 1166.
de Montmollin E, Faille D, Andrieu V, Ajzenberg N, Timsit JF
Intensified thromboprophylaxis in COVID-19 critically ill patients: Is it enough?.
The Journal of Infection 2021
de Montmollin E, Timsit JF
How Antibiotics Stewardship Can Be Safely Implemented in Patients with Septic Shock?.
Seminars in Respiratory and Critical Care Medicine 2021, 42, 689-697.
de Montmollin E, Schwebel C, Dupuis C, Garrouste-Orgeas M, da Silva D, Azoulay E, Laurent V, Thiéry G, Grinea A, Marcotte G, Oziel J, Gainnier M, Siami S, Reignier J, Sztrymf B, Adrie C, Ruckly S, Sonneville R, Timsit JF
Life Support Limitations in Mechanically Ventilated Stroke Patients.
Critical Care Explorations 2021, 3, e0341.
Dupuis C, de Montmollin E, Buetti N, Goldgran-Toledano D, Reignier J, Schwebel C, Domitile J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Laurent V, Gainnier M, Souweine B, Timsit JF, OutcomeReaTM research network
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network.
PloS One 2021, 16, e0255644.
Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.
OUTCOMEREA Study Group, de Montmollin E, Terzi N, Dupuis C, Garrouste-Orgeas M, da Silva D, Darmon M, Laurent V, Thiéry G, Oziel J, Marcotte G, Gainnier M, Siami S, Sztrymf B, Adrie C, Reignier J, Ruckly S, Sonneville R, Timsit JF
One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study.
Annals of Intensive Care 2020, 10, 53.
Jaquet P, de Montmollin E, Dupuis C, Sazio C, Conrad M, Susset V, Demeret S, Tadie JM, Argaud L, Barbier F, Sarton B, Chabane R, Daubin D, Brulé N, Lerolle N, Alves M, Da Silva D, Kalioubi AE, Silva S, Bailly P, Wolff M, Bouadma L, Timsit JF, Sonneville R, ENCEPHALITICA study group
Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study.
Intensive Care Medicine 2019, 45, 1103-1111.
de Montmollin E, Ruckly S, Schwebel C, Philippart F, Adrie C, Mariotte E, Marcotte G, Cohen Y, Sztrymf B, da Silva D, Bruneel F, Gainnier M, Garrouste-Orgeas M, Sonneville R, Timsit JF, OUTCOMEREA Study Group
Pneumonia in acute ischemic stroke patients requiring invasive ventilation: Impact on short and long-term outcomes.
The Journal of Infection 2019, 79, 220-227.
Sonneville R, de Montmollin E, Poujade J, Garrouste-Orgeas M, Souweine B, Darmon M, Mariotte E, Argaud L, Barbier F, Goldgran-Toledano D, Marcotte G, Dumenil AS, Jamali S, Lacave G, Ruckly S, Mourvillier B, Timsit JF
Potentially modifiable factors contributing to sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1075-1084.
de Montmollin E, Demeret S, Brulé N, Conrad M, Dailler F, Lerolle N, Navellou JC, Schwebel C, Alves M, Cour M, Engrand N, Tonnelier JM, Maury E, Ruckly S, Picard G, Rogemond V, Magalhaes É, Sharshar T, Timsit JF, Honnorat J, Sonneville R, ENCEPHALITICA Study Group ‡
Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.
American Journal of Respiratory and Critical Care Medicine 2017, 195, 491-499.
de Montmollin E, Bouadma L, Gault N, Mourvillier B, Mariotte E, Chemam S, Massias L, Papy E, Tubach F, Wolff M, Sonneville R
Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen.
Intensive Care Medicine 2014, 40, 998-1005.
de Montmollin E, Tandjaoui-Lambiotte Y, Legrand M, Lambert J, Mokart D, Kouatchet A, Lemiale V, Pène F, Bruneel F, Vincent F, Mayaux J, Chevret S, Azoulay E
Outcomes in critically ill cancer patients with septic shock of pulmonary origin.
Shock (Augusta, Ga.) 2013, 39, 250-254.
Exhaustive list of publications
2024
Tridon C, Bachelet D, El Baied M, Eloy P, Ortuno S, Para M, Wicky PH, Vellieux G, de Montmollin E, Bouadma L, Manceau H, Timsit JF, Peoc'h K, Sonneville R
Association of Sepsis With Neurologic Outcomes of Adult Patients Treated With Venoarterial Extracorporeal Membrane Oxygnenation.
Critical Care Explorations 2024, 6, e1042.
2023
Sonneville R, de Montmollin E, Contou D, Ferrer R, Gurjar M, Klouche K, Sarton B, Demeret S, Bailly P, da Silva D, Escudier E, Le Guennec L, Chabanne R, Argaud L, Ben Hadj Salem O, Thyrault M, Frerou A, Louis G, De Pascale G, Horn J, Helbok R, Geri G, Bruneel F, Martin-Loeches I, Taccone FS, De Waele JJ, Ruckly S, Staiquly Q, Citerio G, Timsit JF, EURECA Investigator Study Group
Clinical features, etiologies, and outcomes in adult patients with meningoencephalitis requiring intensive care (EURECA): an international prospective multicenter cohort study.
Intensive Care Medicine 2023, 49, 517-529.
Sonneville R, de Montmollin E, Gaudemer A, Ruckly S, Timsit JF
Meningoencephalitis requiring intensive care and neuromonitorization. Author's reply.
Intensive Care Medicine 2023, 49, 884-885.
Celante H, Oubaya N, Fourati S, Beaune S, Khellaf M, Casalino E, Ricard JD, Vieillard-Baron A, Heming N, Mekontso Dessap A, de Montmollin E, Benghanem S, Epaillard N, Layese R, de Prost N, Prono-RSV study group of the clinical data warehouse of Greater Paris University Hospitals
Prognosis of hospitalised adult patients with respiratory syncytial virus infection: a multicentre retrospective cohort study.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2023, 29, 943.e1-943.e8.
Mirouse A, Friol A, Moreau AS, Jung B, Jullien E, Bureau C, Djibré M, de Prost N, Zafrani L, Argaud L, Reuter D, Calvet L, de Montmollin E, Benghanem S, Pichereau C, Pham T, Cacoub P, Biard L, Saadoun D
Severe SARS-Cov2 pneumonia in vaccinated patients: a multicenter cohort study.
Scientific Reports 2023, 13, 1902.
Stern J, Dupuis C, Kpeglo H, Reuter J, Vinclair C, Para M, Nataf P, Pelletier AL, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Upper gastrointestinal bleeding in adults treated with veno-arterial extracorporeal membrane oxygenation: a cohort study.
European Journal of Cardio-Thoracic Surgery: Official Journal of the European Association for Cardio-Thoracic Surgery 2023, 63, ezad083.
Galerneau LM, Bailly S, Terzi N, Ruckly S, Garrouste-Orgeas M, Cohen Y, Hong Tuan Ha V, Gainnier M, Siami S, Dupuis C, Darmon M, Forel JM, Rigault G, Adrie C, Goldgran-Toledano D, Laurent V, de Montmollin E, Argaud L, Reignier J, Pepin JL, Timsit JF, OUTCOMEREA Network
Management of Acute Exacerbations of Chronic Obstructive Pulmonary Disease in the ICU: An Observational Study From the OUTCOMEREA Database, 1997-2018.
Critical Care Medicine 2023, 51, 753-764.
Thy M, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Severe meningoencephalitis: epidemiology and outcomes.
Current Opinion in Critical Care 2023, 29, 415-422.
Sonneville R, Mazighi M, Collet M, Gayat E, Degos V, Duranteau J, Grégoire C, Sharshar T, Naim G, Cortier D, Jost PH, Foucrier A, Bagate F, de Montmollin E, Papin G, Magalhaes E, Guidet B, Ben Hadj Salem O, Benghanem S, le Guennec L, Delpierre E, Legriel S, Megarbane B, Toumert K, Tran M, Geri G, Monchi M, Bodiguel E, Mariotte E, Demoule A, Zarka J, Diehl JL, Roux D, Barré E, Tanaka S, Osman D, Pasquier P, Lamara F, Crassard I, Boursin P, Ruckly S, Staiquly Q, Timsit JF, Woimant F, SPICE Investigators
One-Year Outcomes in Patients With Acute Stroke Requiring Mechanical Ventilation.
Stroke 2023, 54, 2328-2337.
Gaillet A, Azoulay E, de Montmollin E, Garrouste-Orgeas M, Cohen Y, Dupuis C, Schwebel C, Reignier J, Siami S, Argaud L, Adrie C, Mourvillier B, Ruckly S, Forel JM, Timsit JF
Outcomes in critically Ill HIV-infected patients between 1997 and 2020: analysis of the OUTCOMEREA multicenter cohort.
Critical Care (London, England) 2023, 27, 108.
Sonneville R, Benghanem S, Jeantin L, de Montmollin E, Doman M, Gaudemer A, Thy M, Timsit JF
The spectrum of sepsis-associated encephalopathy: a clinical perspective.
Critical Care (London, England) 2023, 27, 386.
Jeantin L, Dupuis C, Vellieux G, Jaquet P, de Montmollin E, Timsit JF, Sonneville R, ENCEPHALITICA Study Group
Electroencephalography for prognostication of outcome in adults with severe herpes simplex encephalitis.
Annals of Intensive Care 2023, 13, 10.
Bourcier S, Coutrot M, Ferré A, Van Grunderbeeck N, Charpentier J, Hraiech S, Azoulay E, Nseir S, Aissaoui N, Messika J, Fillatre P, Persichini R, Carreira S, Lautrette A, Delmas C, Terzi N, Mégarbane B, Lascarrou JB, Razazi K, Repessé X, Pichereau C, Contou D, Frérou A, Barbier F, Ehrmann S, de Montmollin E, Sztrymf B, Morawiec E, Bigé N, Reuter D, Schnell D, Ellrodt O, Dellamonica J, Combes A, Schmidt M
Critically ill severe hypothyroidism: a retrospective multicenter cohort study.
Annals of Intensive Care 2023, 13, 15.
Laurichesse G, Schwebel C, Buetti N, Neuville M, Siami S, Cohen Y, Laurent V, Mourvillier B, Reignier J, Goldgran-Toledano D, Ruckly S, de Montmollin E, Souweine B, Timsit JF, Dupuis C, OUTCOME R. E. A. network
Mortality, incidence, and microbiological documentation of ventilated acquired pneumonia (VAP) in critically ill patients with COVID-19 or influenza.
Annals of Intensive Care 2023, 13, 108.
Galerneau LM, Bailly S, Terzi N, Ruckly S, Garrouste-Orgeas M, Cohen Y, Hong Tuan Ha V, Gainnier M, Siami S, Dupuis C, Darmon M, Azoulay E, Forel JM, Sigaud F, Adrie C, Goldgran-Toledano D, Ferré A, de Montmollin E, Argaud L, Reignier J, Pepin JL, Timsit JF, OUTCOMEREA network
Corticosteroids for severe acute exacerbations of chronic obstructive pulmonary disease in intensive care: From the French OUTCOMEREA cohort.
PloS One 2023, 18, e0284591.
Thy M, Timsit JF, de Montmollin E
Aminoglycosides for the Treatment of Severe Infection Due to Resistant Gram-Negative Pathogens.
Antibiotics (Basel, Switzerland) 2023, 12, 860.
Wicky PH, Dupuis C, Cerf C, Siami S, Cohen Y, Laurent V, Mourvillier B, Reignier J, Goldgran-Toledano D, Schwebel C, Ruckly S, de Montmollin E, Buetti N, Timsit JF
Ventilator-Associated Pneumonia in COVID-19 Patients Admitted in Intensive Care Units: Relapse, Therapeutic Failure and Attributable Mortality-A Multicentric Observational Study from the OutcomeRea Network.
Journal of Clinical Medicine 2023, 12, 1298.
2022
Sonneville R, Jaquet P, Vellieux G, de Montmollin E, Visseaux B
Intensive care management of patients with viral encephalitis.
Revue Neurologique 2022, 178, 48-56.
Giacobbe DR, Roberts JA, Abdul-Aziz MH, de Montmollin E, Timsit JF, Bassetti M
Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: a contemporary, multidisciplinary ESGCIP perspective.
Expert Review of Anti-Infective Therapy 2022, 1-17.
Abid S, Papin G, Vellieux G, de Montmollin E, Wicky PH, Patrier J, Jaquet P, Bouadma L, Rouvel-Tallec A, Timsit JF, Sonneville R
A Simplified Electroencephalography Montage and Interpretation for Evaluation of Comatose Patients in the ICU.
Critical Care Explorations 2022, 4, e0781.
de Montmollin E, Dupuis C, Jaquet P, Sarton B, Sazio C, Susset V, Conrad M, Argaud L, Demeret S, Tadié JM, Barbier F, Wolff M, Timsit JF, Visseaux B, Sonneville R, ENCEPHALITICA Study Group
Herpes Simplex Virus Encephalitis With Initial Negative Polymerase Chain Reaction in the Cerebrospinal Fluid: Prevalence, Associated Factors, and Clinical Impact.
Critical Care Medicine 2022, 50, e643-e648.
Jaquet P, Legouy C, Le Fevre L, Grinea A, Sinnah F, Franchineau G, Patrier J, Marzouk M, Wicky PH, Alexis Geoffroy P, Arnoult F, Vledouts S, de Montmollin E, Bouadma L, Timsit JF, Sharshar T, Sonneville R
Neurologic Outcomes of Survivors of COVID-19-Associated Acute Respiratory Distress Syndrome Requiring Intubation.
Critical Care Medicine 2022, 50, e674-e682.
Valade S, Picard M, Mokart D, Calvet L, Bruneel F, de Montmollin E, Aissaoui N, Champigneulle B, Bigé N, Boissier F, Pène F, Mayaux J, Argaud L, Moreau AS, Murgier M, Azoulay E, Darmon M
Critically ill patients with severe infections related to Geotrichum species: A French retrospective multicentre study.
Mycoses 2022, 65, 226-232.
Patrier J, Villageois-Tran K, Szychowiak P, Ruckly S, Gschwind R, Wicky PH, Gueye S, Armand-Lefevre L, Marzouk M, Sonneville R, Bouadma L, Petitjean M, Lamara F, de Montmollin E, Timsit JF, Ruppé E, French COVID Cohort Study Group
Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults.
Critical Care (London, England) 2022, 26, 300.
Egea A, Dupuis C, de Montmollin E, Wicky PH, Patrier J, Jaquet P, Lefèvre L, Sinnah F, Marzouk M, Sonneville R, Bouadma L, Souweine B, Timsit JF
Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences-a retrospective observational study.
Annals of Intensive Care 2022, 12, 88.
Rambaud T, de Montmollin E, Jaquet P, Gaudemer A, Mariotte E, Abid S, Para M, Cimadevilla C, Iung B, Duval X, Wolff M, Bouadma L, Timsit JF, Sonneville R
Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis.
Annals of Intensive Care 2022, 12, 119.
Timsit JF, Wicky PH, de Montmollin E
Treatment of Severe Infections Due to Metallo-Betalactamases Enterobacterales in Critically Ill Patients.
Antibiotics (Basel, Switzerland) 2022, 11, 144.
de Montmollin E, Peoc'h K, Marzouk M, Ruckly S, Wicky PH, Patrier J, Jaquet P, Sonneville R, Bouadma L, Timsit JF
Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS.
Antibiotics (Basel, Switzerland) 2022, 11, 1166.
Delhommeau G, Buetti N, Neuville M, Siami S, Cohen Y, Laurent V, Mourvillier B, Reignier J, Goldgran-Toledano D, Schwebel C, Ruckly S, de Montmollin E, Souweine B, Timsit JF, Dupuis C
Bacterial Pulmonary Co-Infections on ICU Admission: Comparison in Patients with SARS-CoV-2 and Influenza Acute Respiratory Failure: A Multicentre Cohort Study.
Biomedicines 2022, 10, 2646.
2021
Sarton B, Jaquet P, Belkacemi D, de Montmollin E, Bonneville F, Sazio C, Frérou A, Conrad M, Daubin D, Chabanne R, Argaud L, Dailler F, Brulé N, Lerolle N, Maestraggi Q, Marechal J, Bailly P, Razazi K, Mateos F, Guidet B, Levrat A, Susset V, Lautrette A, Mira JP, El Kalioubie A, Robert A, Massri A, Albucher JF, Olivot JM, Conil JM, Boudma L, Timsit JF, Sonneville R, Silva S, ENCEPHALITICA Consortium
Assessment of Magnetic Resonance Imaging Changes and Functional Outcomes Among Adults With Severe Herpes Simplex Encephalitis.
JAMA network open 2021, 4, e2114328.
Buetti N, Ruckly S, de Montmollin E, Reignier J, Terzi N, Cohen Y, Shiami S, Dupuis C, Timsit JF
COVID-19 increased the risk of ICU-acquired bloodstream infections: a case-cohort study from the multicentric OUTCOMEREA network.
Intensive Care Medicine 2021, 47, 180-187.
de Montmollin E, Faille D, Andrieu V, Ajzenberg N, Timsit JF
Intensified thromboprophylaxis in COVID-19 critically ill patients: Is it enough?.
The Journal of Infection 2021
de Montmollin E, Timsit JF
How Antibiotics Stewardship Can Be Safely Implemented in Patients with Septic Shock?.
Seminars in Respiratory and Critical Care Medicine 2021, 42, 689-697.
Dupuis C, Bouadma L, de Montmollin E, Goldgran-Toledano D, Schwebel C, Reignier J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Grapin K, Laurent V, Buetti N, Gainnier M, Souweine B, Timsit JF
Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia.
Critical Care Explorations 2021, 3, e0329.
de Montmollin E, Schwebel C, Dupuis C, Garrouste-Orgeas M, da Silva D, Azoulay E, Laurent V, Thiéry G, Grinea A, Marcotte G, Oziel J, Gainnier M, Siami S, Reignier J, Sztrymf B, Adrie C, Ruckly S, Sonneville R, Timsit JF
Life Support Limitations in Mechanically Ventilated Stroke Patients.
Critical Care Explorations 2021, 3, e0341.
Legouy C, Girard-Stein L, Wanono R, de Montmollin E, Vellieux G, Bouadma L, Dupuis C, Abid S, Vinclair C, Ruckly S, Rouvel-Tallec A, d'Ortho MP, Timsit JF, Sonneville R
Association of Standard Electroencephalography Findings With Mortality and Command Following in Mechanically Ventilated Patients Remaining Unresponsive After Sedation Interruption.
Critical Care Medicine 2021, 49, e423-e432.
Gault N, Esposito-Farese M, Revest M, Inamo J, Cabie A, Polard É, Hulot JS, Ghosn J, Chirouze C, Deconinck L, Diehl JL, Poissy J, Epaulard O, Lefèvre B, Piroth L, de Montmollin E, Oziol E, Etienne M, Laouenan C, Rossignol P, Costagliola D, Vidal-Petiot E, French-Covid cohort investigators and study group
Chronic use of Renin-Angiotensin-Aldosterone-System blockers and mortality in COVID-19: a multicenter prospective cohort and literature review.
Fundamental & Clinical Pharmacology 2021
Ghanem M, Homps-Legrand M, Garnier M, Morer L, Goletto T, Frija-Masson J, Wicky PH, Jaquet P, Bancal C, Hurtado-Nedelec M, de Chaisemartin L, Jaillet M, Mailleux A, Quesnel C, Poté N, Debray MP, de Montmollin E, Neukirch C, Borie R, Taillé C, Crestani B, French COVID Cohort Study Group
Blood fibrocytes are associated with severity and prognosis in COVID-19 pneumonia.
American Journal of Physiology. Lung Cellular and Molecular Physiology 2021, 321, L847-L858.
Meyer A, Buetti N, Houhou-Fidouh N, Patrier J, Abdel-Nabey M, Jaquet P, Presente S, Girard T, Sayagh F, Ruckly S, Wicky PH, de Montmollin E, Bouadma L, Sonneville R, Descamps D, Timsit JF
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients.
Critical Care (London, England) 2021, 25, 417.
Touchard C, Cartailler J, Vellieux G, de Montmollin E, Jaquet P, Wanono R, Reuter J, Para M, Bouadma L, Timsit JF, d'Ortho MP, Kubis N, Rouvel Tallec A, Sonneville R, DINAMO Study Group
Simplified frontal EEG in adults under veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2021, 11, 76.
Fartoukh M, Voiriot G, Guérin L, Ricard JD, Combes A, Faure M, Benghanem S, de Montmollin E, Tandjaoui-Lambiotte Y, Vieillard-Baron A, Maury E, Diehl JL, Razazi K, Lemiale V, Trouiller P, Planquette B, Savale L, Heming N, Marey J, AP-HP Clinical Data Warehouse, Carrat F, Lapidus N, EPIcuFLU_APHP Group
Seasonal burden of severe influenza virus infection in the critically ill patients, using the Assistance Publique-Hôpitaux de Paris clinical data warehouse: a pilot study.
Annals of Intensive Care 2021, 11, 117.
Gibelin A, Dumas G, Valade S, de Chambrun MP, Bagate F, Neuville M, Schneider F, Baboi L, Groh M, Raphalen JH, Chiche JD, De Prost N, Luyt CE, Guérin C, Maury E, de Montmollin E, Hertig A, Parrot A, Clere-Jehl R, Fartoukh M
Causes of acute respiratory failure in patients with small-vessel vasculitis admitted to intensive care units: a multicenter retrospective study.
Annals of Intensive Care 2021, 11, 158.
Dupuis C, de Montmollin E, Buetti N, Goldgran-Toledano D, Reignier J, Schwebel C, Domitile J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Laurent V, Gainnier M, Souweine B, Timsit JF, OutcomeReaTM research network
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network.
PloS One 2021, 16, e0255644.
Ursino M, Dupuis C, Buetti N, de Montmollin E, Bouadma L, Golgran-Toledano D, Ruckly S, Neuville M, Cohen Y, Mourvillier B, Souweine B, Gainnier M, Laurent V, Terzi N, Shiami S, Reignier J, Alberti C, Timsit JF, On Behalf Of The Outcomerea Study Group n
Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients.
Journal of Clinical Medicine 2021, 10,
2020
Andremont O, Armand-Lefevre L, Dupuis C, de Montmollin E, Ruckly S, Lucet JC, Smonig R, Magalhaes E, Ruppé E, Mourvillier B, Lebut J, Lermuzeaux M, Sonneville R, Bouadma L, Timsit JF, COMBACTE net consortium
Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.
Intensive Care Medicine 2020, 46, 1232-1242.
Wicky PH, Henry-Feugeas MC, Para M, de Montmollin E
Uncharted territories: assessing cerebral vascularization in patients undergoing venoarterial extra-corporeal membrane oxygenation.
Intensive Care Medicine 2020, 46, 2079-2080.
Bouadma L, Wiedemann A, Patrier J, Surénaud M, Wicky PH, Foucat E, Diehl JL, Hejblum BP, Sinnah F, de Montmollin E, Lacabaratz C, Thiébaut R, Timsit JF, Lévy Y
Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome.
Journal of Clinical Immunology 2020, 40, 1082-1092.
Sonneville R, Mazighi M, Bresson D, Crassard I, Crozier S, de Montmollin E, Degos V, Faugeras F, Gayat E, Josse L, Lamy C, Magalhaes E, Maldjian A, Ruckly S, Servan J, Vassel P, Vigué B, Timsit JF, Woimant F, SPICE investigators
Outcomes of Acute Stroke Patients Requiring Mechanical Ventilation: Study Protocol for the SPICE Multicenter Prospective Observational Study.
Neurocritical Care 2020, 32, 624-629.
Magalhaes E, Reuter J, Wanono R, Bouadma L, Jaquet P, Tanaka S, Sinnah F, Ruckly S, Dupuis C, de Montmollin E, Para M, Braham W, Pisani A, d'Ortho MP, Rouvel-Tallec A, Timsit JF, Sonneville R, DINAMO study group
Early EEG for Prognostication Under Venoarterial Extracorporeal Membrane Oxygenation.
Neurocritical Care 2020, 33, 688-694.
Visseaux B, Le Hingrat Q, Collin G, Ferré V, Storto A, Ichou H, Bouzid D, Poey N, de Montmollin E, Descamps D, Houhou-Fidouh N
Evaluation of the RealStar® SARS-CoV-2 RT-PCR kit RUO performances and limit of detection.
Journal of Clinical Virology 2020, 129, 104520.
Ibn Saied W, Merceron S, Schwebel C, Le Monnier A, Oziel J, Garrouste-Orgeas M, Marcotte G, Ruckly S, Souweine B, Darmon M, Bouadma L, de Montmollin E, Mourvillier B, Reignier J, Papazian L, Siami S, Azoulay E, Bédos JP, Timsit JF
Ventilator-associated pneumonia due to Stenotrophomonas maltophilia: Risk factors and outcome.
The Journal of Infection 2020, 80, 279-285.
Lê MP, Jaquet P, Patrier J, Wicky PH, Le Hingrat Q, Veyrier M, Kauv J, Sonneville R, Visseaux B, Laouénan C, Bouadma L, Descamps D, de Montmollin E, Peytavin G, Timsit JF
Pharmacokinetics of lopinavir/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2657-2660.
Reuter J, Peoc'h K, Bouadma L, Ruckly S, Chicha-Cattoir V, Faille D, Bourrienne MC, Dupuis C, Magalhaes E, Tanaka S, Vinclair C, de Montmollin E, Mazighi M, Para M, Braham W, Pisani A, Ajzenberg N, Timsit JF, Sonneville R
Neuron-Specific Enolase Levels in Adults Under Venoarterial Extracorporeal Membrane Oxygenation.
Critical Care Explorations 2020, 2, e0239.
Mirouse A, Parrot A, Audigier V, Demoule A, Mayaux J, Géri G, Mariotte E, Bréchot N, de Prost N, Vautier M, Neuville M, Bigé N, de Montmollin E, Cacoub P, Resche-Rigon M, Cadranel J, Saadoun D
Severe diffuse alveolar hemorrhage related to autoimmune disease: a multicenter study.
Critical Care 2020, 24, 231.
Buetti N, Wicky PH, Le Hingrat Q, Ruckly S, Mazzuchelli T, Loiodice A, Trimboli P, Forni Ogna V, de Montmollin E, Bernasconi E, Visseaux B, Timsit JF
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients.
Critical Care (London, England) 2020, 24, 610.
Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.
OUTCOMEREA Study Group, de Montmollin E, Terzi N, Dupuis C, Garrouste-Orgeas M, da Silva D, Darmon M, Laurent V, Thiéry G, Oziel J, Marcotte G, Gainnier M, Siami S, Sztrymf B, Adrie C, Reignier J, Ruckly S, Sonneville R, Timsit JF
One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study.
Annals of Intensive Care 2020, 10, 53.
Dupuis C, Bouadma L, Ruckly S, Perozziello A, Van-Gysel D, Mageau A, Mourvillier B, de Montmollin E, Bailly S, Papin G, Sinnah F, Vinclair C, Abid S, Sonneville R, Timsit JF
Sepsis and septic shock in France: incidences, outcomes and costs of care.
Annals of Intensive Care 2020, 10, 145.
Sonneville R, Smonig R, Dupuis C, Bouadma L, de Montmollin E, Timsit JF
Natural light exposure and delirium in ICU: does the dark side cloud everything?.
Annals of Intensive Care 2020, 10, 25.
2019
Jaquet P, de Montmollin E, Dupuis C, Sazio C, Conrad M, Susset V, Demeret S, Tadie JM, Argaud L, Barbier F, Sarton B, Chabane R, Daubin D, Brulé N, Lerolle N, Alves M, Da Silva D, Kalioubi AE, Silva S, Bailly P, Wolff M, Bouadma L, Timsit JF, Sonneville R, ENCEPHALITICA study group
Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study.
Intensive Care Medicine 2019, 45, 1103-1111.
de Montmollin E, Ruckly S, Schwebel C, Philippart F, Adrie C, Mariotte E, Marcotte G, Cohen Y, Sztrymf B, da Silva D, Bruneel F, Gainnier M, Garrouste-Orgeas M, Sonneville R, Timsit JF, OUTCOMEREA Study Group
Pneumonia in acute ischemic stroke patients requiring invasive ventilation: Impact on short and long-term outcomes.
The Journal of Infection 2019, 79, 220-227.
Ibn Saied W, Mourvillier B, Cohen Y, Ruckly S, Reignier J, Marcotte G, Siami S, Bouadma L, Darmon M, de Montmollin E, Argaud L, Kallel H, Garrouste-Orgeas M, Soufir L, Schwebel C, Souweine B, Glodgran-Toledano D, Papazian L, Timsit JF
A Comparison of the Mortality Risk Associated With Ventilator-Acquired Bacterial Pneumonia and Nonventilator ICU-Acquired Bacterial Pneumonia*:.
Critical Care Medicine 2019, 47, 345-352.
Bourcier S, Coutrot M, Kimmoun A, Sonneville R, de Montmollin E, Persichini R, Schnell D, Charpentier J, Aubron C, Morawiec E, Bigé N, Nseir S, Terzi N, Razazi K, Azoulay E, Ferré A, Tandjaoui-Lambiotte Y, Ellrodt O, Hraiech S, Delmas C, Barbier F, Lautrette A, Aissaoui N, Repessé X, Pichereau C, Zerbib Y, Lascarrou JB, Carreira S, Reuter D, Frérou A, Peigne V, Fillatre P, Megarbane B, Voiriot G, Combes A, Schmidt M
Thyroid Storm in the ICU: A Retrospective Multicenter Study.
Critical Care Medicine 2019
Balmier A, Dib F, Serret-Larmande A, De Montmollin E, Pouyet V, Sztrymf B, Megarbane B, Thiagarajah A, Dreyfuss D, Ricard JD, Roux D
Initial management of diabetic ketoacidosis and prognosis according to diabetes type: a French multicentre observational retrospective study.
Annals of Intensive Care 2019, 9, 91.
Smonig R, Magalhaes E, Bouadma L, Andremont O, de Montmollin E, Essardy F, Mourvillier B, Lebut J, Dupuis C, Neuville M, Lermuzeaux M, Timsit JF, Sonneville R
Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study.
Annals of Intensive Care 2019, 9, 120.
2018
Garrouste-Orgeas M, Azoulay E, Ruckly S, Schwebel C, de Montmollin E, Bedos JP, Souweine B, Marcotte G, Adrie C, Goldgran-Toledano D, Dumenil AS, Kallel H, Jamali S, Argaud L, Darmon M, Zahar JR, Timsit JF
Diabetes was the only comorbid condition associated with mortality of invasive pneumococcal infection in ICU patients: a multicenter observational study from the Outcomerea research group.
Infection 2018, 46, 669-677.
Gros A, Dupuis C, Ruckly S, Lautrette A, Garrouste-Orgeas M, Gainnier M, Forel JM, Marcotte G, Azoulay E, Cohen Y, Schwebel C, Argaud L, de Montmollin E, Siami S, Goldgran-Toledano D, Darmon M, Timsit JF, OUTCOMEREA Study Group
Association Between Body Weight Variation and Survival and Other Adverse Events in Critically Ill Patients With Shock: A Multicenter Cohort Study of the OUTCOMEREA Network.
Critical Care Medicine 2018, 46, e981-e987.
Cantier M, Morisot A, Guérot E, Megarbane B, Razazi K, Contou D, Mariotte E, Canet E, De Montmollin E, Dubée V, Boulet E, Gaudry S, Voiriot G, Mayaux J, Pène F, Neuville M, Mourvillier B, Ruckly S, Bouadma L, Wolff M, Timsit JF, Sonneville R, ENCEPHALITICA study group
Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study.
Critical Care (London, England) 2018, 22, 210.
2017
Sonneville R, de Montmollin E, Poujade J, Garrouste-Orgeas M, Souweine B, Darmon M, Mariotte E, Argaud L, Barbier F, Goldgran-Toledano D, Marcotte G, Dumenil AS, Jamali S, Lacave G, Ruckly S, Mourvillier B, Timsit JF
Potentially modifiable factors contributing to sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1075-1084.
Yamaga S, Shime N, Sonneville R, de Montmollin E, Timsit JF
Risk factors for sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1548-1549.
de Montmollin E, Demeret S, Brulé N, Conrad M, Dailler F, Lerolle N, Navellou JC, Schwebel C, Alves M, Cour M, Engrand N, Tonnelier JM, Maury E, Ruckly S, Picard G, Rogemond V, Magalhaes É, Sharshar T, Timsit JF, Honnorat J, Sonneville R, ENCEPHALITICA Study Group ‡
Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.
American Journal of Respiratory and Critical Care Medicine 2017, 195, 491-499.
2016
Gélisse E, Neuville M, de Montmollin E, Bouadma L, Mourvillier B, Timsit JF, Sonneville R
Extracorporeal membrane oxygenation (ECMO) does not impact on amikacin pharmacokinetics: a case-control study.
Intensive Care Medicine 2016, 42, 946-948.
2015
Sonneville R, Gault N, de Montmollin E, Klein IF, Mariotte E, Chemam S, Tubach F, Mourvillier B, Timsit JF, Wolff M, Bouadma L
Clinical spectrum and outcomes of patients with encephalitis requiring intensive care.
European Journal of Neurology: The Official Journal of the European Federation of Neurological Societies 2015, 22, 6-16, e1.
2014
de Montmollin E, Bouadma L, Gault N, Mourvillier B, Mariotte E, Chemam S, Massias L, Papy E, Tubach F, Wolff M, Sonneville R
Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen.
Intensive Care Medicine 2014, 40, 998-1005.
2013
de Montmollin E, Tandjaoui-Lambiotte Y, Legrand M, Lambert J, Mokart D, Kouatchet A, Lemiale V, Pène F, Bruneel F, Vincent F, Mayaux J, Chevret S, Azoulay E
Outcomes in critically ill cancer patients with septic shock of pulmonary origin.
Shock (Augusta, Ga.) 2013, 39, 250-254.
2012
de Montmollin E, Corcos O, Noussair L, Leflon-Guibout V, Belmatoug N, Joly F, Lefort A
Retroperitoneal abscesses due to Nocardia farcinica: report of two cases in patients with malnutrition.
Infection 2012, 40, 93-96.