Members
First name: Francois-Xavier Last name: Lescure Function: Professor in Infectious Diseases, researcher Position: Professor in Infectious Diseases at Université Paris Cité Email: xavier.lescure aphp.fr |
Research interest
My main research topics are epidemic risk, emerging infectious diseases, nosocomial infections, antimicrobial resistance, antibacterial stewardship, implementation science, computerized clinical decision support system.
Education
Degree
MD in Public Health and in Infectious Diseases
PhD in Public Health
PhD in Public Health
Academic positions
2019-present: Professor in Infectious Diseases, Medical School, Université Paris Cité
List of the main publications
Exhaustive list of publications
2024
Lavalley-Morelle A, Peiffer-Smadja N, Gressens SB, Souhail B, Lahens A, Bounhiol A, Lescure FX, Mentré F, Mullaert J
Multivariate joint model under competing risks to predict death of hospitalized patients for SARS-CoV-2 infection.
Biometrical Journal. Biometrische Zeitschrift 2024, 66, e2300049.
2023
Celestin B, Habensus EI, Tubiana S, Préau M, Millot S, Lescure FX, Kerneis C, Para M, Duval X, Iung B, POST-IMAGE study group
Determinants of adherence to oral hygiene prophylaxis guidelines in patients with previous infective endocarditis.
Archives of Cardiovascular Diseases 2023, 116, 176-182.
Lefebvre T, Boutten A, Raulet-Bussian C, Raynor A, Manceau H, Puy H, Moulouel B, Schmitt C, Timsit JF, Lefort A, Weiss E, Lescure FX, Ricard JD, Sonneville R, Peoc'h K
Evaluation of iron metabolism in hospitalized COVID-19 patients.
Clinica Chimica Acta; International Journal of Clinical Chemistry 2023, 548, 117509.
Mailhe M, Beaumont AL, Thy M, Le Pluart D, Perrineau S, Houhou-Fidouh N, Deconinck L, Bertin C, Ferré VM, Cortier M, De La Porte Des Vaux C, Phung BC, Mollo B, Cresta M, Bouscarat F, Choquet C, Descamps D, Ghosn J, Lescure FX, Yazdanpanah Y, Joly V, Peiffer-Smadja N
Clinical characteristics of ambulatory and hospitalized patients with monkeypox virus infection: an observational cohort study.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2023, 29, 233-239.
Thy M, Cosson G, Danjou W, Kramer L, Pourcher V, Lescure FX
Comparison between targeted and vaccinated populations during the mpox vaccination campaign in France.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2023, 29, 1351-1353.
Goulenok T, Seurat J, Selle AdL, Jullien V, Leflon-Guibout V, Grall N, Lescure FX, Lepeule R, Bertrand J, Fantin B, Burdet C, Lefort A
Pharmacokinetic interaction between rifampicin and clindamycin in staphylococcal osteoarticular infections.
International Journal of Antimicrobial Agents 2023, 62, 106885.
Chabrol F, Traverson L, Hou R, Chotard L, Lucet JC, Peiffer-Smadja N, Bendjelloul G, Lescure FX, Yazdanpanah Y, Zinszer K, Ridde V
Adaptation and Response of a Major Parisian Referral Hospital to the COVID-19 Surge: A Qualitative Study.
Health Systems and Reform 2023, 9, 2165429.
Bertin C, Beaumont AL, Merlant M, Mailhe M, Le Pluart D, Deconinck L, Thy M, Cortier M, Garé M, Dollat M, Rahi M, Joly V, Lariven S, Rioux C, Truong A, Deschamps L, Ferré VM, Charpentier C, Lescure FX, Bouscarat F, Descamps V, Yazdanpanah Y, Peiffer-Smadja N
Erythematous maculopapular rash in monkeypox virus infection: A retrospective case series of 30 patients.
Journal of the European Academy of Dermatology and Venereology: JEADV 2023, 37, e638-e641.
Pesonel E, Hoffmann I, Guiraud L, Bourner J, Diallo A, Dunning J, Horby P, Kali S, Laouénan C, Mentré F, Merson L, Molino D, Palich R, Rojek A, Tacconelli E, Tardivon C, MOSAIC study group, Yazdanpanah Y, Calmy A, Lescure FX, Olliaro P
MOSAIC: A cohort study of human mpox virus disease.
Wellcome Open Research 2023, 8, 415.
Dinh A, Drouet F, Dechartres A, Yordanov Y, Duran C, Schmidt N, Banzet A, Perrier MH, Mosquet N, Lescure FX, Jourdain P, Nizard J, Masingue X, AP-HP/Universities/Inserm COVID-19 research collaboration
Pregnant women with mild COVID-19 followed in community setting by telemedicine, and factors associated with unfavorable outcome.
PloS One 2023, 18, e0288845.
Kali S, Bourner J, Calmy A, Laouénan C, Merson L, Cervantes-Gonzalez M, Rojek A, Pesonel E, Guiraud L, Tardivon C, Descamps D, Diallo A, Gibowski S, Rosenthal E, Petrov-Sanchez V, Letrou S, Hoffmann I, Le Mestre S, Mentré F, Yazdanpanah Y, Olliaro P, Lescure FX
[MOSAIC: a European cohort study of human Mpox - the challenges of clinical research in outbreaks].
Virologie (Montrouge, France) 2023, 27, 23-26.
Kali S, Bourner J, Calmy A, Laouénan C, Merson L, Cervantes-Gonzalez M, Rojek A, Pesonel E, Guiraud L, Tardivon C, Descamps D, Diallo A, Gibowski S, Rosenthal E, Petrov-Sanchez V, Letrou S, Hoffmann I, Le Mestre S, Mentré F, Yazdanpanah Y, Olliaro P, Lescure FX
MOSAIC: a European cohort study of human Mpox - the challenges of clinical research in outbreaks.
Virologie (Montrouge, France) 2023, 27, 12-15.
2022
Fillâtre P, Dufour MJ, Behillil S, Vatan R, Reusse P, Gabellec A, Velmans N, Montagne C, Geffroy Du Coudret S, Droumaguet E, Merour V, Enouf V, Buzelé R, Valence M, Guillotel E, Gagnière B, Baidaliuk A, Zhukova A, Tourdjman M, Thibault V, Grolhier C, Pronier C, Lescure FX, Simon-Loriere E, Costagliola D, Van Der Werf S, Tattevin P, Massart N
A new SARS-CoV-2 variant with high lethality poorly detected by RT-PCR on nasopharyngeal samples: an observational study.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2022, 28, 298.e9-298.e15.
Dinh A, Dahmane L, Dahoumane M, Masingue X, Jourdain P, Lescure FX
Impact of Omicron surge in community setting in greater Paris area.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2022, S1198-743X(22)00089-1.
Husain M, Valayer S, Poey N, Rondinaud E, d'Humières C, Visseaux B, Lariven S, Lescure FX, Deconinck L
Pulmonary bacterial infections in adult patients hospitalized for COVID-19 in standard wards.
Infectious Diseases Now 2022, 52, 208-213.
Durand C, Chappuis A, Douriez E, Poulain F, Ahmad R, Lescure FX, Peiffer-Smadja N
Perceptions, current practices, and interventions of community pharmacists regarding antimicrobial stewardship: A qualitative study.
Journal of the American Pharmacists Association: JAPhA 2022, S1544-3191(22)00056-5.
Peyneau M, Granger V, Wicky PH, Khelifi-Touhami D, Timsit JF, Lescure FX, Yazdanpanah Y, Tran-Dinh A, Montravers P, Monteiro RC, Chollet-Martin S, Hurtado-Nedelec M, de Chaisemartin L
Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19.
Scientific Reports 2022, 12, 638.
Thy M, Peiffer-Smadja N, Mailhe M, Kramer L, Ferré VM, Houhou N, Tarhini H, Bertin C, Beaumont AL, Garé M, Le Pluart D, Perrineau S, Rahi M, Deconinck L, Phung B, Mollo B, Cortier M, Cresta M, De La Porte Des Vaux C, Joly V, Lariven S, Rioux C, Somarriba C, Lescure FX, Charpentier C, Yazdanpanah Y, Ghosn J
Breakthrough Infections after Postexposure Vaccination against Mpox.
The New England Journal of Medicine 2022, 387, 2477-2479.
Delory T, Le Bel J, Lariven S, Peiffer-Smadja N, Lescure FX, Bouvet E, Jeanmougin P, Tubach F, Boëlle PY
Computerized decision support system (CDSS) use for surveillance of antimicrobial resistance in urinary tract infections in primary care.
The Journal of Antimicrobial Chemotherapy 2022, 77, 524-530.
Le Pluart D, Ruyer-Thompson M, Ferré VM, Mailhe M, Descamps D, Bouscarat F, Lescure FX, Lucet JC, Yazdanpanah Y, Ghosn J
A Healthcare-Associated Infection With Monkeypox Virus of a Healthcare Worker During the 2022 Outbreak.
Open Forum Infectious Diseases 2022, 9, ofac520.
Beurnier A, Yordanov Y, Dechartres A, Dinh A, Debuc E, Lescure FX, Jourdain P, Jaulmes L, Humbert M
Characteristics and outcomes of asthmatic outpatients with COVID-19 who receive home telesurveillance.
ERJ open research 2022, 8, 00012-2022.
Martin-Blondel G, Lescure FX, Assoumou L, Charpentier C, Chapplain JM, Perpoint T, Grouteau G, Cordel H, Pialoux G, Pacanowski J, Thy M, Bauvois A, Laureillard D, Hamrouni F, Algarte-Genin M, Poissy J, Descamps D, Costagliola D, CoCliCo Study Group
Increased risk of severe COVID-19 in hospitalized patients with SARS-CoV-2 Alpha variant infection: a multicentre matched cohort study.
BMC infectious diseases 2022, 22, 540.
Kardaś-Słoma L, Fournier S, Dupont JC, Rochaix L, Birgand G, Zahar JR, Lescure FX, Kernéis S, Durand-Zaleski I, Lucet JC
Cost-effectiveness of strategies to control the spread of carbapenemase-producing Enterobacterales in hospitals: a modelling study.
Antimicrobial Resistance and Infection Control 2022, 11, 117.
Durand C, Douriez E, Chappuis A, Poulain F, Yazdanpanah Y, Lariven S, Lescure FX, Peiffer-Smadja N
Contributions and challenges of community pharmacists during the COVID-19 pandemic: a qualitative study.
Journal of Pharmaceutical Policy and Practice 2022, 15, 43.
Kherabi Y, Mollo B, Gerard S, Lescure FX, Rioux C, Yazdanpanah Y
Patient-centered approach to the management of drug-resistant tuberculosis in France: How far off the mark are we?.
PLOS global public health 2022, 2, e0000313.
d'Humières C, Gaïa N, Gueye S, de Lastours V, Leflon-Guibout V, Maataoui N, Duprilot M, Lecronier M, Rousseau MA, Gamany N, Lescure FX, Senard O, Deconinck L, Dollat M, Isernia V, Le Hur AC, Petitjean M, Nazimoudine A, Le Gac S, Chalal S, Ferreira S, Lazarevic V, Guigon G, Gervasi G, Armand-Lefèvre L, Schrenzel J, Ruppé E
Contribution of Clinical Metagenomics to the Diagnosis of Bone and Joint Infections.
Frontiers in Microbiology 2022, 13, 863777.
Durand C, Alfandari S, Béraud G, Tsopra R, Lescure FX, Peiffer-Smadja N
Clinical Decision Support Systems for Antibiotic Prescribing: An Inventory of Current French Language Tools.
Antibiotics (Basel, Switzerland) 2022, 11, 384.
2021
Tran VT, Mahévas M, Bani-Sadr F, Robineau O, Perpoint T, Perrodeau E, Gallay L, Ravaud P, Goehringer F, Lescure FX, COCORICO Collaborative Group
Corticosteroids in patients hospitalized for COVID-19 pneumonia who require oxygen: observational comparative study using routine care data.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, 27, 603-610.
Gallay L, Tran VT, Perrodeau E, Vignier N, Mahevas M, Bisio F, Forestier E, Lescure FX, COCO-OLD Study group
Fourteen-day survival among older adults with severe infection with severe acute respiratory syndrome coronavirus 2 treated with corticosteroid: a cohort study.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, 27, 1145-1150.
Yordanov Y, Dinh A, Bleibtreu A, Mensch A, Lescure FX, Debuc E, Jourdain P, Jaulmes L, Dechartres A, AP-HP/Universities/Inserm COVID-19 research collaboration
Clinical characteristics and factors associated with hospital admission or death in 43 103 adult outpatients with coronavirus disease 2019 managed with the Covidom telesurveillance solution: a prospective cohort study.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, 27, 1158-1166.
Ader F, Peiffer-Smadja N, Poissy J, Bouscambert-Duchamp M, Belhadi D, Diallo A, Delmas C, Saillard J, Dechanet A, Mercier N, Dupont A, Alfaiate T, Lescure FX, Raffi F, Goehringer F, Kimmoun A, Jaureguiberry S, Reignier J, Nseir S, Danion F, Clere-Jehl R, Bouiller K, Navellou JC, Tolsma V, Cabié A, Dubost C, Courjon J, Leroy S, Mootien J, Gaci R, Mourvillier B, Faure E, Pourcher V, Gallien S, Launay O, Lacombe K, Lanoix JP, Makinson A, Martin-Blondel G, Bouadma L, Botelho-Nevers E, Gagneux-Brunon A, Epaulard O, Piroth L, Wallet F, Richard JC, Reuter J, Staub T, Lina B, Noret M, Andrejak C, Lê MP, Peytavin G, Hites M, Costagliola D, Yazdanpanah Y, Burdet C, Mentré F, DisCoVeRy study group
An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with COVID-19.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, 27, 1826-1837.
Maillet F, Pourbaix A, le Pluart D, Sirmai L, Postolache SA, Couvelard A, Houhou-Fidouh N, Males L, Deconinck L, Lescure FX
Cytomegalovirus proctitis as a complication of COVID-19 with immunosuppressive treatments.
IDCases 2021, 24, e01111.
Gourjault C, Tarhini H, Rahi M, Thy M, Le Pluart D, Rioux C, Parisey M, Ismael S, Al Rida Aidibi A, Paradis V, Ghosn J, Yazdanpanah Y, Lescure FX, Gervais A
Cholangitis in three critically ill patients after a severe CoVID-19 infection.
IDCases 2021, e01267.
Lacarra B, Mellon G, Ortega Perez I, D'Ortenzio E, Lescure FX
Bridging the gap between scientific discovery and clinical application during the COVID-19 epoch.
Infectious Diseases Now 2021, 51, 581-582.
Fournier M, Faille D, Dossier A, Mageau A, Nicaise Roland P, Ajzenberg N, Borie R, Bouadma L, Bunel V, Castier Y, Choquet C, Crestani B, Daugas E, Deconinck L, Descamps D, Descamps V, Dieudé P, Ducrocq G, Faucher N, Goulenok T, Guidoux C, Khalil A, Lavallée P, Lescure FX, Lortat-Jacob B, Mal H, Mutuon P, Pellenc Q, Steg PG, Taille C, Timsit JF, Yazdanpanah Y, Papo T, Sacré K
Arterial Thrombotic Events in Adult Inpatients With COVID-19.
Mayo Clinic Proceedings 2021, 96, 295-303.
Tarhini H, Husain M, Poey N, Lariven S, Lescure FX, Yazdanpanah Y, Gervais A
Jaundice in a patient treated with Anakinra in a context of Covid-19.
Infectious Diseases Now 2021, 51, 217-218.
Sallard E, Belhadi D, Lescure FX, Yazdanpanah Y, Peiffer-Smadja N
Clinical trial protocols of repurposed prophylaxis for COVID-19: A review.
Infectious Diseases Now 2021, 51, 7-13.
Frija-Masson J, Debray MP, Boussouar S, Khalil A, Bancal C, Motiejunaite J, Galarza-Jimenez MA, Benzaquen H, Penaud D, Laveneziana P, Malrin R, Redheuil A, Donciu V, Lucidarme O, Taillé C, Guerder A, Arnoult F, Vidal-Petiot E, Flamant M, Similowski T, Morelot-Panzini C, Faure M, Lescure FX, Straus C, d'Ortho MP, Gonzalez-Bermejo J
Residual ground glass opacities three months after Covid-19 pneumonia correlate to alteration of respiratory function: The post Covid M3 study.
Respiratory Medicine 2021, 184, 106435.
Lescure FX, Honda H, Fowler RA, Lazar JS, Shi G, Wung P, Patel N, Hagino O, Sarilumab COVID-19 Global Study Group
Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial.
The Lancet. Respiratory Medicine 2021, 9, 522-532.
Néant N, Lingas G, Le Hingrat Q, Ghosn J, Engelmann I, Lepiller Q, Gaymard A, Ferré V, Hartard C, Plantier JC, Thibault V, Marlet J, Montes B, Bouiller K, Lescure FX, Timsit JF, Faure E, Poissy J, Chidiac C, Raffi F, Kimmoun A, Etienne M, Richard JC, Tattevin P, Garot D, Le Moing V, Bachelet D, Tardivon C, Duval X, Yazdanpanah Y, Mentré F, Laouénan C, Visseaux B, Guedj J, French COVID Cohort Investigators and French Cohort Study groups
Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort.
Proceedings of the National Academy of Sciences of the United States of America 2021, 118,
Tarhini H, Recoing A, Bridier-Nahmias A, Rahi M, Lambert C, Martres P, Lucet JC, Rioux C, Bouzid D, Lebourgeois S, Descamps D, Yazdanpanah Y, Le Hingrat Q, Lescure FX, Visseaux B
Long-Term Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infectiousness Among Three Immunocompromised Patients: From Prolonged Viral Shedding to SARS-CoV-2 Superinfection.
The Journal of Infectious Diseases 2021, 223, 1522-1527.
Bouzid D, Casalino E, Mullaert J, Laurent O, Duval X, Lescure FX, Peiffer Smadja N, Tubiana S, Armand Lefèvre L, Descamps D, Fidouh N, Choquet C, Lucet JC, Visseaux B
Added value of rapid respiratory syndromic testing at point of care versus central laboratory testing: a controlled clinical trial.
The Journal of Antimicrobial Chemotherapy 2021, 76, iii20-iii27.
Lahens A, Mullaert J, Gressens S, Gault N, Flamant M, Deconinck L, Joly V, Yazdanpanah Y, Lescure FX, Vidal-Petiot E
Association between renin-angiotensin-aldosterone system blockers and outcome in coronavirus disease 2019: analysing in-hospital exposure generates a biased seemingly protective effect of treatment.
Journal of Hypertension 2021, 39, 367-375.
Le Hingrat Q, Bouzid D, Choquet C, Laurent O, Lescure FX, Timsit JF, Houhou-Fidouh N, Casalino E, Lucet JC, Descamps D, Visseaux B
Viral epidemiology and SARS-CoV-2 co-infections with other respiratory viruses during the first COVID-19 wave in Paris, France.
Influenza and Other Respiratory Viruses 2021, 15, 425-428.
Rahi M, Le Pluart D, Beaudet A, Ismaël S, Parisey M, Poey N, Tarhini H, Lescure FX, Yazdanpanah Y, Deconinck L
Sociodemographic characteristics and transmission risk factors in patients hospitalized for COVID-19 before and during the lockdown in France.
BMC infectious diseases 2021, 21, 812.
Sanchez MA, Vuagnat A, Grimaud O, Leray E, Philippe JM, Lescure FX, Boutonnet M, Coignard H, Hibon AR, Sanchez S, Pottecher J
Impact of ICU transfers on the mortality rate of patients with COVID-19: insights from comprehensive national database in France.
Annals of Intensive Care 2021, 11, 151.
Denis F, Fontanet A, Le Douarin YM, Le Goff F, Jeanneau S, Lescure FX
A Self-Assessment Web-Based App to Assess Trends of the COVID-19 Pandemic in France: Observational Study.
Journal of Medical Internet Research 2021, 23, e26182.
Denis F, Septans AL, Le Goff F, Jeanneau S, Lescure FX
Analysis of COVID-19 Transmission Sources in France by Self-Assessment Before and After the Partial Lockdown: Observational Study.
Journal of Medical Internet Research 2021, 23, e26932.
Brossas JY, Griselda B, Bisio M, Guihenneuc J, Gulin JEN, Jauréguiberry S, Lescure FX, Fekkar A, Mazier D, Altcheh J, Paris L
Evaluation of the Chagas Western Blot IgG Assay for the Diagnosis of Chagas Disease.
Pathogens (Basel, Switzerland) 2021, 10, 1455.
2020
Birgand G, Peiffer-Smadja N, Fournier S, Kerneis S, Lescure FX, Lucet JC
Assessment of Air Contamination by SARS-CoV-2 in Hospital Settings.
JAMA network open 2020, 3, e2033232.
Bouadma L, Lescure FX, Lucet JC, Yazdanpanah Y, Timsit JF
Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists.
Intensive Care Medicine 2020, 46, 579-582.
Moulignier A, Viret-Vilayphon AC, Lescure FX, Plaisier E, Salomon L, Lamirel C, Pialoux G, ALCOVE Study Group
Microalbuminuria: a sentinel of neurocognitive impairment in HIV-infected individuals?.
Journal of Neurology 2020, 267, 1368-1376.
Sallard E, Lescure FX, Yazdanpanah Y, Mentre F, Peiffer-Smadja N
Type 1 interferons as a potential treatment against COVID-19.
Antiviral Research 2020, 178, 104791.
Peiffer-Smadja N, Rawson TM, Ahmad R, Buchard A, Georgiou P, Lescure FX, Birgand G, Holmes AH
Machine learning for clinical decision support in infectious diseases: a narrative review of current applications.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, 26, 584-595.
Peiffer-Smadja N, Dellière S, Rodriguez C, Birgand G, Lescure FX, Fourati S, Ruppé E
Machine learning in the clinical microbiology laboratory: has the time come for routine practice?.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, 26, 1300-1309.
Peiffer-Smadja N, Lucet JC, Bendjelloul G, Bouadma L, Gerard S, Choquet C, Jacques S, Khalil A, Maisani P, Casalino E, Descamps D, Timsit JF, Yazdanpanah Y, Lescure FX
Challenges and issues about organising a hospital to respond to the COVID-19 outbreak: experience from a French reference centre.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020
Fragkou PC, Belhadi D, Peiffer-Smadja N, Moschopoulos CD, Lescure FX, Janocha H, Karofylakis E, Yazdanpanah Y, Mentré F, Skevaki C, Laouénan C, Tsiodras S, ESCMID Study Group for Respiratory Viruses
Review of trials currently testing treatment and prevention of COVID-19.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, 26, 988-998.
Peyronnet V, Sibiude J, Huissoud C, Lescure FX, Lucet JC, Mandelbrot L, Nisand I, Belaish-Allart J, Vayssière C, Yazpandanah Y, Luton D, Picone O
[Infection with SARS-CoV-2 in pregnancy. Update of Information and proposed care. CNGOF].
Gynecologie, Obstetrique, Fertilite & Senologie 2020, 48, 858-870.
Dubert M, Visseaux B, Isernia V, Bouadma L, Deconinck L, Patrier J, Wicky PH, Le Pluart D, Kramer L, Rioux C, Le Hingrat Q, Houhou-Fidouh N, Yazdanpanah Y, Ghosn J, Lescure FX
Case report study of the first five COVID-19 patients treated with remdesivir in France.
International Journal of Infectious Diseases 2020, 98, 290-293.
Gousseff M, Penot P, Gallay L, Batisse D, Benech N, Bouiller K, Collarino R, Conrad A, Slama D, Joseph C, Lemaignen A, Lescure FX, Levy B, Mahevas M, Pozzetto B, Vignier N, Wyplosz B, Salmon D, Goehringer F, Botelho-Nevers E, in behalf of the COCOREC study group
Clinical recurrences of COVID-19 symptoms after recovery: Viral relapse, reinfection or inflammatory rebound?.
The Journal of Infection 2020, 81, 816-846.
Pizzorno A, Padey B, Julien T, Trouillet-Assant S, Traversier A, Errazuriz-Cerda E, Fouret J, Dubois J, Gaymard A, Lescure FX, Dulière V, Brun P, Constant S, Poissy J, Lina B, Yazdanpanah Y, Terrier O, Rosa-Calatrava M
Characterization and Treatment of SARS-CoV-2 in Nasal and Bronchial Human Airway Epithelia.
Cell Reports Medicine 2020, 1, 100059.
Lescure FX, Bouadma L, Nguyen D, Parisey M, Wicky PH, Behillil S, Gaymard A, Bouscambert-Duchamp M, Donati F, Le Hingrat Q, Enouf V, Houhou-Fidouh N, Valette M, Mailles A, Lucet JC, Mentre F, Duval X, Descamps D, Malvy D, Timsit JF, Lina B, van-der-Werf S, Yazdanpanah Y
Clinical and virological data of the first cases of COVID-19 in Europe: a case series.
The Lancet. Infectious Diseases 2020, 20, 697-706.
Grein J, Ohmagari N, Shin D, Diaz G, Asperges E, Castagna A, Feldt T, Green G, Green ML, Lescure FX, Nicastri E, Oda R, Yo K, Quiros-Roldan E, Studemeister A, Redinski J, Ahmed S, Bernett J, Chelliah D, Chen D, Chihara S, Cohen SH, Cunningham J, D'Arminio Monforte A, Ismail S, Kato H, Lapadula G, L'Her E, Maeno T, Majumder S, Massari M, Mora-Rillo M, Mutoh Y, Nguyen D, Verweij E, Zoufaly A, Osinusi AO, DeZure A, Zhao Y, Zhong L, Chokkalingam A, Elboudwarej E, Telep L, Timbs L, Henne I, Sellers S, Cao H, Tan SK, Winterbourne L, Desai P, Mera R, Gaggar A, Myers RP, Brainard DM, Childs R, Flanigan T
Compassionate Use of Remdesivir for Patients with Severe Covid-19.
The New England Journal of Medicine 2020
Delory T, Jeanmougin P, Lariven S, Aubert JP, Peiffer-Smadja N, Boëlle PY, Bouvet E, Lescure FX, Le Bel J
A computerized decision support system (CDSS) for antibiotic prescription in primary care-Antibioclic: implementation, adoption and sustainable use in the era of extended antimicrobial resistance.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2353-2362.
Peiffer-Smadja N, Lescure FX, Sallard E, Ravaud P, Vegreville B, Zeitoun JD
Anticovid, a comprehensive open-access real-time platform of registered clinical studies for COVID-19.
Journal of Antimicrobial Chemotherapy 2020, 75, 2708-2710.
Lescure FX, Fellahi S, Pialoux G, Bastard JP, Eme AL, Esteve E, Lebrette MG, Guiard-Schmid JB, Capeau J, Ronco P, Costagliola D, Plaisier E
Prevalence of tubulopathy and association with renal function loss in HIV-infected patients.
Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association 2020, 35, 607-615.
Visseaux B, Le Hingrat Q, Collin G, Bouzid D, Lebourgeois S, Le Pluart D, Deconinck L, Lescure FX, Lucet JC, Bouadma L, Timsit JF, Descamps D, Yazdanpanah Y, Casalino E, Houhou-Fidouh N, McAdam AJ
Evaluation of the QIAstat-Dx Respiratory SARS-CoV-2 Panel, the First Rapid Multiplex PCR Commercial Assay for SARS-CoV-2 Detection.
Journal of Clinical Microbiology 2020, 58, e00630-20, /jcm/58/8/JCM.00630-20.atom.
Mahévas M, Tran VT, Roumier M, Chabrol A, Paule R, Guillaud C, Fois E, Lepeule R, Szwebel TA, Lescure FX, Schlemmer F, Matignon M, Khellaf M, Crickx E, Terrier B, Morbieu C, Legendre P, Dang J, Schoindre Y, Pawlotsky JM, Michel M, Perrodeau E, Carlier N, Roche N, de Lastours V, Ourghanlian C, Kerneis S, Ménager P, Mouthon L, Audureau E, Ravaud P, Godeau B, Gallien S, Costedoat-Chalumeau N
Clinical efficacy of hydroxychloroquine in patients with covid-19 pneumonia who require oxygen: observational comparative study using routine care data.
BMJ 2020, m1844.
Frija-Masson J, Debray MP, Gilbert M, Lescure FX, Travert F, Borie R, Khalil A, Crestani B, d'Ortho MP, Bancal C
Functional characteristics of patients with SARS-CoV-2 pneumonia at 30 days post infection.
European Respiratory Journal 2020, 2001754.
Dubert M, Visseaux B, Birgy A, Mordant P, Metivier AC, Dauriat G, Fidouh N, Yazdanpanah Y, Grall N, Castier Y, Mal H, Thabut G, Lescure FX
Late viral or bacterial respiratory infections in lung transplanted patients: impact on respiratory function.
BMC infectious diseases 2020, 20, 176.
Kardaś-Słoma L, Yazdanpanah Y, Perozziello A, Zahar JR, Lescure FX, Cousien A, Lucet JC
Hand hygiene improvement or antibiotic restriction to control the household transmission of extended-spectrum β-lactamase-producing Escherichia coli: a mathematical modelling study.
Antimicrobial Resistance and Infection Control 2020, 9, 139.
Lamirel C, Valin N, Savatovsky J, Lescure FX, Alonso AS, Girard P, Vincensini JP, Girard PM, Salomon L, Cochereau I, Moulignier A, Lewin AS
Absence of peripapillary retinal nerve-fiber–layer thinning in combined antiretroviral therapy-treated, well-sustained aviremic persons living with HIV.
PLOS ONE 2020, 15, e0229977.
Borie R, Savale L, Dossier A, Ghosn J, Taillé C, Visseaux B, Jebreen K, Diallo A, Tesmoingt C, Morer L, Goletto T, Faucher N, Hajouji L, Neukirch C, Phillips M, Stelianides S, Bouadma L, Brosseau S, Ottaviani S, Pluvy J, Le Pluart D, Debray MP, Raynaud-Simon A, Descamps D, Khalil A, Timsit JF, Lescure FX, Descamps V, Papo T, Humbert M, Crestani B, Dieude P, Vicaut E, Zalcman G, Bichat & Kremlin-Bicêtre AP-HP COVID teams
Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study.
PloS One 2020, 15, e0243961.
Peiffer-Smadja N, Poda A, Ouedraogo AS, Guiard-Schmid JB, Delory T, Le Bel J, Bouvet E, Lariven S, Jeanmougin P, Ahmad R, Lescure FX
Paving the Way for the Implementation of a Decision Support System for Antibiotic Prescribing in Primary Care in West Africa: Preimplementation and Co-Design Workshop With Physicians.
Journal of Medical Internet Research 2020, 22, e17940.
Denis F, Galmiche S, Dinh A, Fontanet A, Scherpereel A, Benezit F, Lescure FX
Epidemiological Observations on the Association Between Anosmia and COVID-19 Infection: Analysis of Data From a Self-Assessment Web Application.
Journal of Medical Internet Research 2020, 22, e19855.
Galmiche S, Rahbe E, Fontanet A, Dinh A, Bénézit F, Lescure FX, Denis F
Implementation of a Self-Triage Web Application for Suspected COVID-19 and Its Impact on Emergency Call Centers: Observational Study.
Journal of Medical Internet Research 2020, 22, e22924.
Bernard Stoecklin S, Rolland P, Silue Y, Mailles A, Campese C, Simondon A, Mechain M, Meurice L, Nguyen M, Bassi C, Yamani E, Behillil S, Ismael S, Nguyen D, Malvy D, Lescure FX, Georges S, Lazarus C, Tabaï A, Stempfelet M, Enouf V, Coignard B, Levy-Bruhl D, Investigation team
First cases of coronavirus disease 2019 (COVID-19) in France: surveillance, investigations and control measures, January 2020.
Eurosurveillance 2020, 25,
2019
Perozziello A, Lescure FX, Truel A, Routelous C, Vaillant L, Yazdanpanah Y, Lucet JC, CEFECA study group
Prescribers' experience and opinions on antimicrobial stewardship programmes in hospitals: a French nationwide survey.
The Journal of Antimicrobial Chemotherapy 2019, 74, 2451-2458.
Peiffer-Smadja N, Guillotel E, Luque-Paz D, Maataoui N, Lescure FX, Cattoir V
In vitro bactericidal activity of amoxicillin combined with different cephalosporins against endocarditis-associated Enterococcus faecalis clinical isolates.
Journal of Antimicrobial Chemotherapy 2019, 74, 3511-3514.
Januel E, Godin O, Moulignier A, Lescure FX, Savatovsky J, Lamirel C, Valin N, Tubiana R, Canestri A, Roux P, Sadik JC, Salomon L, Katlama C, Yazdanpanah Y, Pialoux G, Girard PM, Costagliola D, Assoumou L, Microvascular Brain Retina And Kidney (MicroBREAK) Study Group
Brief Report: Impact of ART Classes on the Increasing Risk of Cerebral Small-Vessel Disease in Middle-Aged, Well-Controlled, cART-Treated, HIV-Infected Individuals.
Journal of Acquired Immune Deficiency Syndromes (1999) 2019, 81, 547-551.
Charani E, Smith I, Skodvin B, Perozziello A, Lucet JC, Lescure FX, Birgand G, Poda A, Ahmad R, Singh S, Holmes AH
Investigating the cultural and contextual determinants of antimicrobial stewardship programmes across low-, middle- and high-income countries-A qualitative study.
PloS One 2019, 14, e0209847.
2018
Loubet P, Burdet C, Vindrios W, Grall N, Wolff M, Yazdanpanah Y, Andremont A, Duval X, Lescure FX
Cefazolin versus anti-staphylococcal penicillins for treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a narrative review.
Clin Microbiol Infect 2018, 24, 125-132.
Jolivet S, Lescure FX, Armand-Lefevre L, Raffoul R, Dilly MP, Ghodbane W, Nataf P, Lucet JC
Surgical site infection with extended-spectrum β-lactamase-producing Enterobacteriaceae after cardiac surgery: incidence and risk factors.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 283-288.
Ruppe E, Burdet C, Grall N, de Lastours V, Lescure FX, Andremont A, Armand-Lefevre L
Impact of antibiotics on the intestinal microbiota needs to be re-defined to optimize antibiotic usage.
Clin Microbiol Infect 2018, 24, 3-5.
Peiffer-Smadja N, Abbara S, Rizk N, Pogliaghi M, Rondinaud E, Tesmoingt C, Massias L, Lucet JC, Alkhoder S, Armand-Lefèvre L, Lescure FX
High-dose daptomycin in patients with infective endocarditis or sternal wound infections.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 1106-1108.
Cez A, Brocheriou I, Lescure FX, Adam C, Girard PM, Pialoux G, Moestrup SK, Fellahi S, Bastard JP, Ronco P, Plaisier E
Decreased expression of megalin and cubilin and altered mitochondrial activity in tenofovir nephrotoxicity.
Human Pathology 2018, 73, 89-101.
Perozziello A, Routelous C, Charani E, Truel A, Birgand G, Yazdanpanah Y, Lescure FX, Lucet JC, CEFECA Study Group
Experiences and perspectives of implementing antimicrobial stewardship in five French hospitals: a qualitative study.
International Journal of Antimicrobial Agents 2018, 51, 829-835.
Moulignier A, Savatovsky J, Assoumou L, Lescure FX, Lamirel C, Godin O, Valin N, Tubiana R, Canestri A, Roux P, Sadik JC, Salomon L, Abrivard M, Katlama C, Yazdanpanah Y, Pialoux G, Girard PM, Costagliola D, Microvascular Brain Retina and Kidney (MicroBREAK) Study Group
Silent Cerebral Small-Vessel Disease Is Twice as Prevalent in Middle-Aged Individuals With Well-Controlled, Combination Antiretroviral Therapy-Treated Human Immunodeficiency Virus (HIV) Than in HIV-Uninfected Individuals.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018, 66, 1762-1769.
Peiffer-Smadja N, Hanslik T, Mordant P, Lescure FX
Cultural differences between surgical and medical teams: is it time for comanagement?.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018
Burdet C, Loubet P, Le Moing V, Vindrios W, Esposito-Farèse M, Linard M, Ferry T, Massias L, Tattevin P, Wolff M, Vandenesch F, Grall N, Quintin C, Mentré F, Duval X, Lescure FX, CloCeBa study group
Efficacy of cloxacillin versus cefazolin for methicillin-susceptible Staphylococcus aureus bacteraemia (CloCeBa): study protocol for a randomised, controlled, non-inferiority trial.
BMJ open 2018, 8, e023151.
Januel E, Martin-Blondel G, Lamirel C, Picard H, Pialoux G, Katlama C, Cochereau I, Lescure FX, Moulignier A
Do CCR5 antagonists improve the overall survival of patients with AIDS-related progressive multifocal leucoencephalopathy?.
Journal of Neurology, Neurosurgery, and Psychiatry 2018, 89, 1125-1126.
Bleibtreu A, Jaureguiberry S, Houhou N, Boutolleau D, Guillot H, Vallois D, Lucet JC, Robert J, Mourvillier B, Delemazure J, Jaspard M, Lescure FX, Rioux C, Caumes E, Yazdanapanah Y
Clinical management of respiratory syndrome in patients hospitalized for suspected Middle East respiratory syndrome coronavirus infection in the Paris area from 2013 to 2016.
BMC infectious diseases 2018, 18, 331.
2017
Bleibtreu A, Arias P, Vallois D, Debit A, Lermuzeaux M, Rioux C, Cabras O, Lucet JC, Choquet C, Timsit JF, Yazdanpanah Y, Lescure FX
Delayed management of Staphyloccocus aureus infective endocarditis in a Middle East respiratory syndrome coronavirus possible case hospitalized in 2015 in Paris, France.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2017, 23, 416-417.
Loubet P, Voiriot G, Houhou-Fidouh N, Neuville M, Bouadma L, Lescure FX, Descamps D, Timsit JF, Yazdanpanah Y, Visseaux B
Impact of respiratory viruses in hospital-acquired pneumonia in the intensive care unit: A single-center retrospective study.
Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology 2017, 91, 52-57.
Vindrios W, Argy N, Le Gal S, Lescure FX, Massias L, Le MP, Wolff M, Yazdanpanah Y, Nevez G, Houze S, Dorent R, Lucet JC
Outbreak of Pneumocystis jirovecii Infection Among Heart Transplant Recipients: Molecular Investigation and Management of an Interhuman Transmission.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2017, 65, 1120-1126.
Lemaignen A, Ghout I, Dinh A, Gras G, Fantin B, Zarrouk V, Carlier R, Loret JE, Denes E, Greder A, Lescure FX, Boutoille D, Tattevin P, Issartel B, Cottier JP, Bernard L
Characteristics of and risk factors for severe neurological deficit in patients with pyogenic vertebral osteomyelitis: A case-control study..
Medicine 2017, 96, e6387.
Visseaux B, Burdet C, Voiriot G, Lescure FX, Chougar T, Brugiere O, Crestani B, Casalino E, Charpentier C, Descamps D, Timsit JF, Yazdanpanah Y, Houhou-Fidouh N
Prevalence of respiratory viruses among adults, by season, age, respiratory tract region and type of medical unit in Paris, France, from 2011 to 2016.
PLoS One 2017, 12, e0180888.
Haddad E, Lescure FX, Ghodhbane W, Lepage L, D'humieres C, Vindrios W, Yazdanpanah Y, Nataf P, Kirsch M
Left ventricular assist pump pocket infection: conservative treatment strategy for destination therapy candidates.
The International Journal of Artificial Organs 2017, 40, 90-95.
2016
Lemaire X, Bonnet E, Castan B, Forestier E, Lescure FX, Roblot F, Pulcini C
Management of non-necrotizing cellulitis in France.
Medecine Et Maladies Infectieuses 2016, 46, 355-359.
Collarino R, Vergeylen U, Emeraud C, Latournèrie G, Grall N, Mammeri H, Messika-Zeitoun D, Vallois D, Yazdanpanah Y, Lescure FX, Bleibtreu A
Mitral endocarditis due to Rothia aeria with cerebral haemorrhage and femoral mycotic aneurysms, first French description.
New Microbes and New Infections 2016, 13, 40-42.
Voiriot G, Visseaux B, Cohen J, Nguyen LB, Neuville M, Morbieu C, Burdet C, Radjou A, Lescure FX, Smonig R, Armand-Lefevre L, Mourvillier B, Yazdanpanah Y, Soubirou JF, Ruckly S, Houhou-Fidouh N, Timsit JF
Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia.
Crit Care 2016, 20, 375.
2015
Lemaignen A, Birgand G, Ghodhbane W, Alkhoder S, Lolom I, Belorgey S, Lescure FX, Armand-Lefevre L, Raffoul R, Dilly MP, Nataf P, Lucet JC
Sternal wound infection after cardiac surgery: incidence and risk factors according to clinical presentation.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015, 21, 674.e11-18.
Lefébure A, Papy E, Rioux C, Diamantis S, Armand-Lefèvre L, Longuet P, Lescure FX, Wolff M, Arnaud P, Lucet JC
Audit of carbapenem prescriptions comparing 2 assessment periods.
Medecine Et Maladies Infectieuses 2015, 45, 273-278.
Moulignier A, Gueguen A, Lescure FX, Ziegler M, Girard PM, Cardon B, Pialoux G, Molina JM, Brandel JP, Lamirel C
Does HIV Infection Alter Parkinson Disease?.
Journal of Acquired Immune Deficiency Syndromes (1999) 2015, 70, 129-136.
Chas J, Hema A, Slama L, Kabore NF, Lescure FX, Fontaine C, Pialoux G, Sawadogo A
The Day-Hospital of the University Hospital, Bobo Dioulasso: An Example of Optimized HIV Management in Southern Burkina Faso.
PloS One 2015, 10, e0125588.
Dubert M, Pourbaix A, Alkhoder S, Mabileau G, Lescure FX, Ghodhbane W, Belorgey S, Rioux C, Armand-Lefèvre L, Wolff M, Raffoul R, Nataf P, Yazdanpanah Y, Lucet JC
Sternal Wound Infection after Cardiac Surgery: Management and Outcome.
PloS One 2015, 10, e0139122.
Loubet P, Lescure FX, Lepage L, Kirsch M, Armand-Lefevre L, Bouadma L, Lariven S, Duval X, Yazdanpanah Y, Joly V
Endocarditis due to gram-negative bacilli at a French teaching hospital over a 6-year period: clinical characteristics and outcome.
Infectious Diseases (London, England) 2015, 47, 889-895.
2014
Izzedine H, Lescure FX, Bonnet F
HIV medication-based urolithiasis.
Clinical Kidney Journal 2014, 7, 121-126.
Nguyen LBL, Harent S, Peytavin G, Visseaux B, Bastard JP, Dubourg O, Lariven S, Patrick Yeni n, Yazdanpanah Y, Lescure FX
Skeletal muscle toxicity associated with emtricitabine/rilpivirine/tenofovir fixed-dose combination: a case report.
AIDS (London, England) 2014, 28, 1995-1997.
Moulignier A, Lescure FX, Savatovsky J, Campa P
CD8 transverse myelitis in a patient with HIV-1 infection.
BMJ case reports 2014, 2014,
2013
Moulignier A, Savatovsky J, Polivka M, Boutboul D, Depaz R, Lescure FX
CD8 T lymphocytes encephalitis mimicking brain tumor in HIV-1 infection.
Journal of Neurovirology 2013, 19, 606-609.
Chakvetadze C, Bani-Sadr F, Lescure FX, Fontaine C, Le Pendeven C, Bonnard P, Mariot P, Soussan P, Pialoux G
Liver stiffness values in HIV-infected patients with isolated anti-hepatitis B core antibodies.
Medecine Et Maladies Infectieuses 2013, 43, 222-225.
Lescure FX, Moulignier A, Savatovsky J, Amiel C, Carcelain G, Molina JM, Gallien S, Pacanovski J, Pialoux G, Adle-Biassette H, Gray F
CD8 encephalitis in HIV-infected patients receiving cART: a treatable entity.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2013, 57, 101-108.
Gray F, Lescure FX, Adle-Biassette H, Polivka M, Gallien S, Pialoux G, Moulignier A
Encephalitis with infiltration by CD8+ lymphocytes in HIV patients receiving combination antiretroviral treatment.
Brain Pathology (Zurich, Switzerland) 2013, 23, 525-533.
Zaidan M, Lescure FX, Brochériou I, Dettwiler S, Guiard-Schmid JB, Pacanowski J, Rondeau E, Pialoux G, Girard PM, Ronco P, Plaisier E
Tubulointerstitial nephropathies in HIV-infected patients over the past 15 years: a clinico-pathological study.
Clinical journal of the American Society of Nephrology: CJASN 2013, 8, 930-938.
2012
Boissier F, Khalil A, Chalumeau-Lemoine L, Lescure FX, Parrot A
Rash diagnosis of blood expectoration.
Lancet (London, England) 2012, 379, 1170.
Lescure FX, Flateau C, Pacanowski J, Brocheriou I, Rondeau E, Girard PM, Ronco P, Pialoux G, Plaisier E
HIV-associated kidney glomerular diseases: changes with time and HAART.
Nephrology, Dialysis, Transplantation: Official Publication of the European Dialysis and Transplant Association - European Renal Association 2012, 27, 2349-2355.