Members

  First name: Jean-Francois
  Last name: Timsit
  Function: Head of the medical and infectious diseases ICU APHP Bichat
  Position: MD PhD Prof
  Email: jean-francois.timsit
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bch.aphp.fr

Research interest


sepsis septic shock nosocomial infections and multidrug resistant bacteria determinants of prognosis survival models causal inference high quality multicenter databases

Education

Degree

MD 1989
PhD 2002 epidemiology and clinical reaserch Nancy I
Research Habilitation 2000 Paris Diderot university
Professor of intensive care medicine 2004 Grenoble 1 university

Academic positions

Professor of intensive care medicine Paris Diderot university Paris France


Research training (post doctoral)

Epidemiology clinical and interventional

List of the main publications

Bailly S, Pirracchio R, Timsit JF
What's new in the quantification of causal effects from longitudinal cohort studies: a brief introduction to marginal structural models for intensivists.
Intensive Care Medicine 2016, 42, 576-579.

Gélisse E, Neuville M, de Montmollin E, Bouadma L, Mourvillier B, Timsit JF, Sonneville R
Extracorporeal membrane oxygenation (ECMO) does not impact on amikacin pharmacokinetics: a case-control study.
Intensive Care Medicine 2016, 42, 946-948.

Bailly S, Maubon D, Fournier P, Pelloux H, Schwebel C, Chapuis C, Foroni L, Cornet M, Timsit JF
Impact of antifungal prescription on relative distribution and susceptibility of Candida spp. - Trends over 10 years.
The Journal of Infection 2016, 72, 103-111.

Tabah A, Cotta MO, Garnacho-Montero J, Schouten J, Roberts JA, Lipman J, Tacey M, Timsit JF, Leone M, Zahar JR, De Waele JJ, WGfAUitI
A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2016, 62, 1009-1017.

Barbier F, Pommier C, Essaied W, Garrouste-Orgeas M, Schwebel C, Ruckly S, Dumenil AS, Lemiale V, Mourvillier B, Clec'h C, Darmon M, Laurent V, Marcotte G, Lucet JC, Souweine B, Zahar JR, Timsit JF, OSG
Colonization and infection with extended-spectrum β-lactamase-producing Enterobacteriaceae in ICU patients: what impact on outcomes and carbapenem exposure?.
The Journal of Antimicrobial Chemotherapy 2016, 71, 1088-1097.

Garrouste-Orgeas M, Max A, Lerin T, Grégoire C, Ruckly S, Kloeckner M, Brochon S, Pichot E, Simons C, El-Mhadri M, Bruel C, Philippart F, Fournier J, Tiercelet K, Timsit JF, Misset B
Impact of Proactive Nurse Participation in ICU Family Conferences: A Mixed-Method Study.
Critical Care Medicine 2016, 44, 1116-1128.

Pépin JL, Tamisier R, Baguet JP, Lepaulle B, Arbib F, Arnol N, Timsit JF, Lévy P
Fixed-pressure CPAP versus auto-adjusting CPAP: comparison of efficacy on blood pressure in obstructive sleep apnoea, a randomised clinical trial.
Thorax 2016, 71, 726-733.

Paiva JA, Pereira JM, Tabah A, Mikstacki A, de Carvalho FB, Koulenti D, Ruckly S, Çakar N, Misset B, Dimopoulos G, Antonelli M, Rello J, Ma X, Tamowicz B, Timsit JF
Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study.
Critical Care (London, England) 2016, 20,

Leroy O, Bailly S, Gangneux JP, Mira JP, Devos P, Dupont H, Montravers P, Perrigault PF, Constantin JM, Guillemot D, Azoulay E, Lortholary O, Bensoussan C, Timsit JF, Asg
Systemic antifungal therapy for proven or suspected invasive candidiasis: the AmarCAND 2 study.
Annals of Intensive Care 2016, 6, 2.

Garrouste-Orgeas M, Ruckly S, Grégoire C, Dumesnil AS, Pommier C, Jamali S, Golgran-Toledano D, Schwebel C, Clec'h C, Soufir L, Fartoukh M, Marcotte G, Argaud L, Verdière B, Darmon M, Azoulay E, Timsit JF
Treatment intensity and outcome of nonagenarians selected for admission in ICUs: a multicenter study of the Outcomerea Research Group.
Annals of Intensive Care 2016, 6, 31.

Reignier J, Darmon M, Sonneville R, Borel AL, Garrouste-Orgeas M, Ruckly S, Souweine B, Dumenil AS, Haouache H, Adrie C, Argaud L, Soufir L, Marcotte G, Laurent V, Goldgran-Toledano D, Clec'h C, Schwebel C, Azoulay E, Timsit JF
Impact of early nutrition and feeding route on outcomes of mechanically ventilated patients with shock: a post hoc marginal structural model study.
Intensive Care Medicine 2015, 41, 875-886.

Lautrette A, Garrouste-Orgeas M, Bertrand PM, Goldgran-Toledano D, Jamali S, Laurent V, Argaud L, Schwebel C, Mourvillier B, Darmon M, Ruckly S, Dumenil AS, Lemiale V, Souweine B, Timsit JF, OSG
Respective impact of no escalation of treatment, withholding and withdrawal of life-sustaining treatment on ICU patients' prognosis: a multicenter study of the Outcomerea Research Group.
Intensive Care Medicine 2015, 41, 1763-1772.

Bailly S, Leroy O, Montravers P, Constantin JM, Dupont H, Guillemot D, Lortholary O, Mira JP, Perrigault PF, Gangneux JP, Azoulay E, Timsit JF
Antifungal de-escalation was not associated with adverse outcome in critically ill patients treated for invasive candidiasis: post hoc analyses of the AmarCAND2 study data.
Intensive Care Medicine 2015, 41, 1931-1940.

Garnacho-Montero J, Dimopoulos G, Poulakou G, Akova M, Cisneros JM, De Waele J, Petrosillo N, Seifert H, Timsit JF, Vila J, Zahar JR, Bassetti M, ESoICM
Task force on management and prevention of Acinetobacter baumannii infections in the ICU.
Intensive Care Medicine 2015, 41, 2057-2075.

Shadoud L, Almahmoud I, Jarraud S, Etienne J, Larrat S, Schwebel C, Timsit JF, Schneider D, Maurin M
Hidden Selection of Bacterial Resistance to Fluoroquinolones In Vivo: The Case of Legionella pneumophila and Humans.
EBioMedicine 2015, 2, 1179-1185.

Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S, Friggeri A, Wallet F, Allou N, Ruckly S, Balayn D, Lepape A, Timsit JF, Cti
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.
Lancet (London, England) 2015, 386, 2069-2077.

Tabah A, De Waele J, Lipman J, Zahar JR, Cotta MO, Barton G, Timsit JF, Roberts JA, WGfAUitIwtISotESoICM(
The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs.
The Journal of Antimicrobial Chemotherapy 2015, 70, 2671-2677.

Bouadma L, Sonneville R, Garrouste-Orgeas M, Darmon M, Souweine B, Voiriot G, Kallel H, Schwebel C, Goldgran-Toledano D, Dumenil AS, Argaud L, Ruckly S, Jamali S, Planquette B, Adrie C, Lucet JC, Azoulay E, Timsit JF, OSG
Ventilator-Associated Events: Prevalence, Outcome, and Relationship With Ventilator-Associated Pneumonia.
Critical Care Medicine 2015, 43, 1798-1806.

Souweine B, Lautrette A, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Guelon D, Darmon M, Vesin A, Caillot N, Schwebel C, Boyer A, Azoulay E, Bouadma L, Timsit JF
Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2015, 191, 1024-1032.

Venot M, Weis L, Clec'h C, Darmon M, Allaouchiche B, Goldgran-Tolédano D, Garrouste-Orgeas M, Adrie C, Timsit JF, Azoulay E
Acute Kidney Injury in Severe Sepsis and Septic Shock in Patients with and without Diabetes Mellitus: A Multicenter Study.
PloS One 2015, 10, e0127411.

Maunoury F, Motrunich A, Palka-Santini M, Bernatchez SF, Ruckly S, Timsit JF
Cost-Effectiveness Analysis of a Transparent Antimicrobial Dressing for Managing Central Venous and Arterial Catheters in Intensive Care Units.
PloS One 2015, 10, e0130439.

Debaty G, Maignan M, Savary D, Koch FX, Ruckly S, Durand M, Picard J, Escallier C, Chouquer R, Santre C, Minet C, Guergour D, Hammer L, Bouvaist H, Belle L, Adrie C, Payen JF, Carpentier F, Gueugniaud PY, Danel V, Timsit JF
Impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial.
Intensive Care Medicine 2014, 40, 1832-1842.

Garrouste-Orgeas M, Tabah A, Vesin A, Philippart F, Kpodji A, Bruel C, Grégoire C, Max A, Timsit JF, Misset B
The ETHICA study (part II): simulation study of determinants and variability of ICU physician decisions in patients aged 80 or over.
Intensive Care Medicine 2013, 39, 1574-1583.

Zahar JR, Garrouste-Orgeas M, Vesin A, Schwebel C, Bonadona A, Philippart F, Ara-Somohano C, Misset B, Timsit JF
Impact of contact isolation for multidrug-resistant organisms on the occurrence of medical errors and adverse events.
Intensive Care Medicine 2013, 39, 2153-2160.

Annane D, Timsit JF, Megarbane B, Martin C, Misset B, Mourvillier B, Siami S, Chagnon JL, Constantin JM, Petitpas F, Souweine B, Amathieu R, Forceville X, Charpentier C, Tesnière A, Chastre J, Bohe J, Colin G, Cariou A, Renault A, Brun-Buisson C, Bellissant E, ATI
Recombinant human activated protein C for adults with septic shock: a randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2013, 187, 1091-1097.

Parienti JJ, du Cheyron D, Timsit JF, Traoré O, Kalfon P, Mimoz O, Mermel LA
Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adults.
Critical Care Medicine 2012, 40, 1627-1634.

Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Lepape A, Vesin A, Arrault X, Schwebel C, Adrie C, Zahar JR, Ruckly S, Tournegros C, Lucet JC
Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults.
American Journal of Respiratory and Critical Care Medicine 2012, 186, 1272-1278.


Exhaustive list of publications

2022


Bassetti M, Vena A, Giacobbe DR, Trucchi C, Ansaldi F, Antonelli M, Adamkova V, Alicino C, Almyroudi MP, Atchade E, Azzini AM, Brugnaro P, Carannante N, Peghin M, Berruti M, Carnelutti A, Castaldo N, Corcione S, Cortegiani A, Dimopoulos G, Dubler S, García-Garmendia JL, Girardis M, Cornely OA, Ianniruberto S, Kullberg BJ, Lagrou K, Lebihan C, Luzzati R, Malbrain M, Merelli M, Marques AJ, Martin-Loeches I, Mesini A, Paiva JA, Raineri SM, Rautemaa-Richardson R, Schouten J, Spapen H, Tasioudis P, Timsit JF, Tisa V, Tumbarello M, Van den Berg CHSB, Veber B, Venditti M, Voiriot G, Wauters J, Zappella N, Montravers P, ftSGfIiCIP(otESoCMaID(
Risk Factors for Intra-Abdominal Candidiasis in Intensive Care Units: Results from EUCANDICU Study.
Infectious Diseases and Therapy 2022, 11, 827-840.

Buetti N, Mermel LA, Timsit JF
Routine catheter-tip cultures for assessing catheter-related bloodstream infections in randomised-controlled trials.
Anaesthesia, Critical Care & Pain Medicine 2022, 41, 101006.

Blot S, Ruppé E, Harbarth S, Asehnoune K, Poulakou G, Luyt CE, Rello J, Klompas M, Depuydt P, Eckmann C, Martin-Loeches I, Povoa P, Bouadma L, Timsit JF, Zahar JR
Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies.
Intensive & Critical Care Nursing 2022, 70, 103227.

Arvaniti K, Dimopoulos G, Antonelli M, Blot K, Creagh-Brown B, Deschepper M, de Lange D, De Waele J, Dikmen Y, Eckmann C, Einav S, Francois G, Fjeldsoee-Nielsen H, Girardis M, Jovanovic B, Lindner M, Koulenti D, Labeau S, Lipman J, Lipovestky F, Makikado LDU, Maseda E, Mikstacki A, Montravers P, Paiva JA, Pereyra C, Rello J, Timsit JF, Tomescu D, Vogelaers D, Blot S, ASS(gobotTGotESoICM
Epidemiology and Age-Related Mortality in Critically Ill Patients With Intra-Abdominal Infection or Sepsis: An International Cohort Study.
International Journal of Antimicrobial Agents 2022, 106591.

Lebourgeois S, Menidjel R, Chenane HR, Ferré VM, Collin G, Damond F, Coppée R, Yazdanpanah Y, Timsit JF, Houhou-Fidouh N, Descamps D, Charpentier C, Visseaux B
Alpha (B.1.1.7) and Delta (B.1.617.2 - AY.40) SARS-CoV-2 variants present strong neutralization decay at M4 post-vaccination and a faster replication rates than D614G (B.1) lineage.
The Journal of Infection 2022, 84, 418-467.

Nasa P, Azoulay E, Chakrabarti A, Divatia JV, Jain R, Rodrigues C, Rosenthal VD, Alhazzani W, Arabi YM, Bakker J, Bassetti M, De Waele J, Dimopoulos G, Du B, Einav S, Evans L, Finfer S, Guérin C, Hammond NE, Jaber S, Kleinpell RM, Koh Y, Kollef M, Levy MM, Machado FR, Mancebo J, Martin-Loeches I, Mer M, Niederman MS, Pelosi P, Perner A, Peter JV, Phua J, Piquilloud L, Pletz MW, Rhodes A, Schultz MJ, Singer M, Timsit JF, Venkatesh B, Vincent JL, Welte T, Myatra SN
Infection control in the intensive care unit: expert consensus statements for SARS-CoV-2 using a Delphi method.
The Lancet. Infectious Diseases 2022, 22, e74-e87.

Gangneux JP, Dannaoui E, Fekkar A, Luyt CE, Botterel F, De Prost N, Tadié JM, Reizine F, Houzé S, Timsit JF, Iriart X, Riu-Poulenc B, Sendid B, Nseir S, Persat F, Wallet F, Le Pape P, Canet E, Novara A, Manai M, Cateau E, Thille AW, Brun S, Cohen Y, Alanio A, Mégarbane B, Cornet M, Terzi N, Lamhaut L, Sabourin E, Desoubeaux G, Ehrmann S, Hennequin C, Voiriot G, Nevez G, Aubron C, Letscher-Bru V, Meziani F, Blaize M, Mayaux J, Monsel A, Boquel F, Robert-Gangneux F, Le Tulzo Y, Seguin P, Guegan H, Autier B, Lesouhaitier M, Pelletier R, Belaz S, Bonnal C, Berry A, Leroy J, François N, Richard JC, Paulus S, Argaud L, Dupont D, Menotti J, Morio F, Soulié M, Schwebel C, Garnaud C, Guitard J, Le Gal S, Quinio D, Morcet J, Laviolle B, Zahar JR, Bougnoux ME
Fungal infections in mechanically ventilated patients with COVID-19 during the first wave: the French multicentre MYCOVID study.
The Lancet. Respiratory Medicine 2022, 10, 180-190.

Peyneau M, Granger V, Wicky PH, Khelifi-Touhami D, Timsit JF, Lescure FX, Yazdanpanah Y, Tran-Dinh A, Montravers P, Monteiro RC, Chollet-Martin S, Hurtado-Nedelec M, de Chaisemartin L
Innate immune deficiencies are associated with severity and poor prognosis in patients with COVID-19.
Scientific Reports 2022, 12, 638.

Wicky PH, Martin-Loeches I, Timsit JF
HAP and VAP after Guidelines.
Seminars in Respiratory and Critical Care Medicine 2022, 43, 248-254.

Giacobbe DR, Roberts JA, Abdul-Aziz MH, de Montmollin E, Timsit JF, Bassetti M
Treatment of ventilator-associated pneumonia due to carbapenem-resistant Gram-negative bacteria with novel agents: a contemporary, multidisciplinary ESGCIP perspective.
Expert Review of Anti-Infective Therapy 2022, 1-17.

Timsit JF, Paul M, Shields RK, Echols R, Baba T, Yamano Y, Portsmouth S
Cefiderocol for the Treatment of Infections Due To Metallo-Beta-Lactamase-Producing Pathogens in the CREDIBLE-CR And APEKS-NP Phase 3 Randomized Studies.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2022, ciac078.

Martin-Loeches I, Timsit JF, Kollef MH, Wunderink RG, Shime N, Nováček M, Kivistik Ü, Réa-Neto Á, Bruno CJ, Huntington JA, Lin G, Jensen EH, Motyl M, Yu B, Gates D, Butterton JR, Rhee EG
Clinical and microbiological outcomes, by causative pathogen, in the ASPECT-NP randomized, controlled, Phase 3 trial comparing ceftolozane/tazobactam and meropenem for treatment of hospital-acquired/ventilator-associated bacterial pneumonia.
The Journal of Antimicrobial Chemotherapy 2022, 77, 1166-1177.

Vacheron CH, Lepape A, Savey A, Machut A, Timsit JF, Vanhems P, Le QV, Egbeola J, Martin M, Maxime V, Pugliesi PS, Maucort-Boulch D, Friggeri A, RRSG
Increased Incidence of Ventilator-Acquired Pneumonia in Coronavirus Disease 2019 Patients: A Multicentric Cohort Study.
Critical Care Medicine 2022, 50, 449-459.

de Montmollin E, Dupuis C, Jaquet P, Sarton B, Sazio C, Susset V, Conrad M, Argaud L, Demeret S, Tadié JM, Barbier F, Wolff M, Timsit JF, Visseaux B, Sonneville R, ESG
Herpes Simplex Virus Encephalitis With Initial Negative Polymerase Chain Reaction in the Cerebrospinal Fluid: Prevalence, Associated Factors, and Clinical Impact.
Critical Care Medicine 2022

Jaquet P, Legouy C, Le Fevre L, Grinea A, Sinnah F, Franchineau G, Patrier J, Marzouk M, Wicky PH, Alexis Geoffroy P, Arnoult F, Vledouts S, de Montmollin E, Bouadma L, Timsit JF, Sharshar T, Sonneville R
Neurologic Outcomes of Survivors of COVID-19-Associated Acute Respiratory Distress Syndrome Requiring Intubation.
Critical Care Medicine 2022

Wicky PH, d'Humières C, Timsit JF
How common is ventilator-associated pneumonia after coronavirus disease 2019?.
Current Opinion in Infectious Diseases 2022, 35, 170-175.

Mageau A, Borie R, Crestani B, Timsit JF, Papo T, Sacre K
Epidemiology of interstitial lung disease in systemic lupus erythematosus in France: A nation-wide population-based study over 10 years.
Respirology (Carlton, Vic.) 2022

Wymant C, Bezemer D, Blanquart F, Ferretti L, Gall A, Hall M, Golubchik T, Bakker M, Ong SH, Zhao L, Bonsall D, de Cesare M, MacIntyre-Cockett G, Abeler-Dörner L, Albert J, Bannert N, Fellay J, Grabowski MK, Gunsenheimer-Bartmeyer B, Günthard HF, Kivelä P, Kouyos RD, Laeyendecker O, Meyer L, Porter K, Ristola M, van Sighem A, Berkhout B, Kellam P, Cornelissen M, Reiss P, Fraser C, NAHOC, BC, Aubert V, Battegay M, Bernasconi E, Böni J, Braun DL, Bucher HC, Burton-Jeangros C, Calmy A, Cavassini M, Dollenmaier G, Egger M, Elzi L, Fehr J, Fellay J, Furrer H, Fux CA, Gorgievski M, Günthard H, Haerry D, Hasse B, Hirsch HH, Hoffmann M, Hösli I, Kahlert C, Kaiser L, Keiser O, Klimkait T, Kouyos R, Kovari H, Ledergerber B, Martinetti G, de Tejada BM, Marzolini C, Metzner K, Müller N, Nadal D, Nicca D, Pantaleo G, Rauch A, Regenass S, Rudin C, Schöni-Affolter F, Schmid P, Speck R, Stöckle M, Tarr P, Trkola A, Vernazza P, Weber R, Yerly S, van der Valk M, Geerlings SE, Goorhuis A, Hovius JW, Lempkes B, Nellen FJB, van der Poll T, Prins JM, Reiss P, van Vugt M, Wiersinga WJ, Wit FWMN, van Duinen M, van Eden J, Hazenberg A, van Hes AMH, Pijnappel FJJ, Smalhout SY, Weijsenfeld AM, Jurriaans S, Back NKT, Zaaijer HL, Berkhout B, Cornelissen MTE, Schinkel CJ, Wolthers KC, Peters EJG, van Agtmael MA, Autar RS, Bomers M, Sigaloff KCE, Heitmuller M, Laan LM, Ang CW, van Houdt R, Jonges M, Kuijpers TW, Pajkrt D, Scherpbier HJ, de Boer C, van der Plas A, van den Berge M, Stegeman A, Baas S, Hage de Looff L, Buiting A, Reuwer A, Veenemans J, Wintermans B, Pronk MJH, Ammerlaan HSM, van den Bersselaar DNJ, de Munnik ES, Deiman B, Jansz AR, Scharnhorst V, Tjhie J, Wegdam MCA, van Eeden A, Nellen J, Brokking W, Elsenburg LJM, Nobel H, van Kasteren MEE, Berrevoets MaH, Brouwer AE, Adams A, van Erve R, de Kruijf-van de Wiel BaFM, Keelan-Phaf S, van de Ven B, van der Ven B, Buiting AGM, Murck JL, de Vries-Sluijs TEMS, Bax HI, van Gorp ECM, de Jong-Peltenburg NC, de Mendonç A Melo M, van Nood E, Nouwen JL, Rijnders BJA, Rokx C, Schurink CaM, Slobbe L, Verbon A, Bassant N, van Beek JEA, Vriesde M, van Zonneveld LM, de Groot J, Boucher CaB, Koopmans MPG, van Kampen JJA, Fraaij PLA, van Rossum AMC, Vermont CL, van der Knaap LC, Visser E, Branger J, Douma RA, Cents-Bosma AS, Duijf-van de Ven CJHM, Schippers EF, van Nieuwkoop C, van Ijperen JM, Geilings J, van der Hut G, van Burgel ND, Leyten EMS, Gelinck LBS, Mollema F, Davids-Veldhuis S, Tearno C, Wildenbeest GS, Heikens E, Groeneveld PHP, Bouwhuis JW, Lammers AJJ, Kraan S, van Hulzen AGW, Kruiper MSM, van der Bliek GL, Bor PCJ, Debast SB, Wagenvoort GHJ, Kroon FP, de Boer MGJ, Jolink H, Lambregts MMC, Roukens AHE, Scheper H, Dorama W, van Holten N, Claas ECJ, Wessels E, den Hollander JG, El Moussaoui R, Pogany K, Brouwer CJ, Smit JV, Struik-Kalkman D, van Niekerk T, Pontesilli O, Lowe SH, Oude Lashof AML, Posthouwer D, van Wolfswinkel ME, Ackens RP, Burgers K, Schippers J, Weijenberg-Maes B, van Loo IHM, Havenith TRA, van Vonderen MGA, Kampschreur LM, Faber S, Steeman-Bouma R, Al Moujahid A, Kootstra GJ, Delsing CE, van der Burg-van de Plas M, Scheiberlich L, Kortmann W, van Twillert G, Renckens R, Ruiter-Pronk D, van Truijen-Oud FA, Cohen Stuart JWT, Jansen ER, Hoogewerf M, Rozemeijer W, van der Reijden WA, Sinnige JC, Brinkman K, van den Berk GEL, Blok WL, Lettinga KD, de Regt M, Schouten WEM, Stalenhoef JE, Veenstra J, Vrouenraets SME, Blaauw H, Geerders GF, Kleene MJ, Kok M, Knapen M, van der Meché IB, Mulder-Seeleman E, Toonen AJM, Wijnands S, Wttewaal E, Kwa D, van Crevel R, van Aerde K, Dofferhoff ASM, Henriet SSV, Ter Hofstede HJM, Hoogerwerf J, Keuter M, Richel O, Albers M, Grintjes-Huisman KJT, de Haan M, Marneef M, Strik-Albers R, Rahamat-Langendoen J, Stelma FF, Burger D, Gisolf EH, Hassing RJ, Claassen M, Ter Beest G, van Bentum PHM, Langebeek N, Tiemessen R, Swanink CMA, van Lelyveld SFL, Soetekouw R, van der Prijt LMM, van der Swaluw J, Bermon N, van der Reijden WA, Jansen R, Herpers BL, Veenendaal D, Verhagen DWM, Lauw FN, van Broekhuizen MC, van Wijk M, Bierman WFW, Bakker M, Kleinnijenhuis J, Kloeze E, Middel A, Postma DF, Schölvinck EH, Stienstra Y, Verhage AR, Wouthuyzen-Bakker M, Boonstra A, de Groot-de Jonge H, van der Meulen PA, de Weerd DA, Niesters HGM, van Leer-Buter CC, Knoester M, Hoepelman AIM, Arends JE, Barth RE, Bruns AHW, Ellerbroek PM, Mudrikova T, Oosterheert JJ, Schadd EM, van Welzen BJ, Aarsman K, Griffioen-van Santen BMG, de Kroon I, van Berkel M, van Rooijen CSaM, Schuurman R, Verduyn-Lunel F, Wensing AMJ, Bont LJ, Geelen SPM, Loeffen YGT, Wolfs TFW, Nauta N, Rooijakkers EOW, Holtsema H, Voigt R, van de Wetering D, Alberto A, van der Meer I, Rosingh A, Halaby T, Zaheri S, Boyd AC, Bezemer DO, van Sighem AI, Smit C, Hillebregt M, de Jong A, Woudstra T, Bergsma D, Meijering R, van de Sande L, Rutkens T, van der Vliet S, de Groot L, van den Akker M, Bakker Y, El Berkaoui A, Bezemer M, Brétin N, Djoechro E, Groters M, Kruijne E, Lelivelt KJ, Lodewijk C, Lucas E, Munjishvili L, Paling F, Peeck B, Ree C, Regtop R, Ruijs Y, Schoorl M, Schnörr P, Scheigrond A, Tuijn E, Veenenberg L, Visser KM, Witte EC, Ruijs Y, Van Frankenhuijsen M, Allegre T, Makhloufi D, Livrozet JM, Chiarello P, Godinot M, Brunel-Dalmas F, Gibert S, Trepo C, Peyramond D, Miailhes P, Koffi J, Thoirain V, Brochier C, Baudry T, Pailhes S, Lafeuillade A, Philip G, Hittinger G, Assi A, Lambry V, Rosenthal E, Naqvi A, Dunais B, Cua E, Pradier C, Durant J, Joulie A, Quinsat D, Tempesta S, Ravaux I, Martin IP, Faucher O, Cloarec N, Champagne H, Pichancourt G, Morlat P, Pistone T, Bonnet F, Mercie P, Faure I, Hessamfar M, Malvy D, Lacoste D, Pertusa MC, Vandenhende MA, Bernard N, Paccalin F, Martell C, Roger-Schmelz J, Receveur MC, Duffau P, Dondia D, Ribeiro E, Caltado S, Neau D, Dupont M, Dutronc H, Dauchy F, Cazanave C, Vareil MO, Wirth G, Le Puil S, Pellegrin JL, Raymond I, Viallard JF, Chaigne de Lalande S, Garipuy D, Delobel P, Obadia M, Cuzin L, Alvarez M, Biezunski N, Porte L, Massip P, Debard A, Balsarin F, Lagarrigue M, Prevoteau du Clary F, Aquilina C, Reynes J, Baillat V, Merle C, Lemoing V, Atoui N, Makinson A, Jacquet JM, Psomas C, Tramoni C, Aumaitre H, Saada M, Medus M, Malet M, Eden A, Neuville S, Ferreyra M, Sotto A, Barbuat C, Rouanet I, Leureillard D, Mauboussin JM, Lechiche C, Donsesco R, Cabie A, Abel S, Pierre-Francois S, Batala AS, Cerland C, Rangom C, Theresine N, Hoen B, Lamaury I, Fabre I, Schepers K, Curlier E, Ouissa R, Gaud C, Ricaud C, Rodet R, Wartel G, Sautron C, Beck-Wirth G, Michel C, Beck C, Halna JM, Kowalczyk J, Benomar M, Drobacheff-Thiebaut C, Chirouze C, Faucher JF, Parcelier F, Foltzer A, Haffner-Mauvais C, Hustache Mathieu M, Proust A, Piroth L, Chavanet P, Duong M, Buisson M, Waldner A, Mahy S, Gohier S, Croisier D, May T, Delestan M, Andre M, Zadeh MM, Martinot M, Rosolen B, Pachart A, Martha B, Jeunet N, Rey D, Cheneau C, Partisani M, Priester M, Bernard-Henry C, Batard ML, Fischer P, Berger JL, Kmiec I, Robineau O, Huleux T, Ajana F, Alcaraz I, Allienne C, Baclet V, Meybeck A, Valette M, Viget N, Aissi E, Biekre R, Cornavin P, Merrien D, Seghezzi JC, Machado M, Diab G, Raffi F, Bonnet B, Allavena C, Grossi O, Reliquet V, Billaud E, Brunet C, Bouchez S, Morineau-Le Houssine P, Sauser F, Boutoille D, Besnier M, Hue H, Hall N, Brosseau D, Souala F, Michelet C, Tattevin P, Arvieux C, Revest M, Leroy H, Chapplain JM, Dupont M, Fily F, Patra-Delo S, Lefeuvre C, Bernard L, Bastides F, Nau P, Verdon R, de la Blanchardiere A, Martin A, Feret P, Geffray L, Daniel C, Rohan J, Fialaire P, Chennebault JM, Rabier V, Abgueguen P, Rehaiem S, Luycx O, Niault M, Moreau P, Poinsignon Y, Goussef M, Mouton-Rioux V, Houlbert D, Alvarez-Huve S, Barbe F, Haret S, Perre P, Leantez-Nainville S, Esnault JL, Guimard T, Suaud I, Girard JJ, Simonet V, Debab Y, Schmit JL, Jacomet C, Weinberck P, Genet C, Pinet P, Ducroix S, Durox H, Denes É, Abraham B, Gourdon F, Antoniotti O, Molina JM, Ferret S, Lascoux-Combe C, Lafaurie M, Colin de Verdiere N, Ponscarme D, De Castro N, Aslan A, Rozenbaum W, Pintado C, Clavel F, Taulera O, Gatey C, Munier AL, Gazaigne S, Penot P, Conort G, Lerolle N, Leplatois A, Balausine S, Delgado J, Timsit J, Tabet M, Gerard L, Girard PM, Picard O, Tredup J, Bollens D, Valin N, Campa P, Bottero J, Lefebvre B, Tourneur M, Fonquernie L, Wemmert C, Lagneau JL, Yazdanpanah Y, Phung B, Pinto A, Vallois D, Cabras O, Louni F, Pialoux G, Lyavanc T, Berrebi V, Chas J, Lenagat S, Rami A, Diemer M, Parrinello M, Depond A, Salmon D, Guillevin L, Tahi T, Belarbi L, Loulergue P, Zak Dit Zbar O, Launay O, Silbermann B, Leport C, Alagna L, Pietri MP, Simon A, Bonmarchand M, Amirat N, Pichon F, Kirstetter M, Katlama C, Valantin MA, Tubiana R, Caby F, Schneider L, Ktorza N, Calin R, Merlet A, Ben Abdallah S, Weiss L, Buisson M, Batisse D, Karmochine M, Pavie J, Minozzi C, Jayle D, Castel P, Derouineau J, Kousignan P, Eliazevitch M, Pierre I, Collias L, Viard JP, Gilquin J, Sobel A, Slama L, Ghosn J, Hadacek B, Thu-Huyn N, Nait-Ighil L, Cros A, Maignan A, Duvivier C, Consigny PH, Lanternier F, Shoai-Tehrani M, Touam F, Jerbi S, Bodard L, Jung C, Goujard C, Quertainmont Y, Duracinsky M, Segeral O, Blanc A, Peretti D, Cheret A, Chantalat C, Dulucq MJ, Levy Y, Lelievre JD, Lascaux AS, Dumont C, Boue F, Chambrin V, Abgrall S, Kansau I, Raho-Moussa M, De Truchis P, Dinh A, Davido B, Marigot D, Berthe H, Devidas A, Chevojon P, Chabrol A, Agher N, Lemercier Y, Chaix F, Turpault I, Bouchaud O, Honore P, Rouveix E, Reimann E, Belan AG, Godin Collet C, Souak S, Mortier E, Bloch M, Simonpoli AM, Manceron V, Cahitte I, Hiraux E, Lafon E, Cordonnier F, Zeng AF, Zucman D, Majerholc C, Bornarel D, Uludag A, Gellen-Dautremer J, Lefort A, Bazin C, Daneluzzi V, Gerbe J, Jeantils V, Coupard M, Patey O, Bantsimba J, Delllion S, Paz PC, Cazenave B, Richier L, Garrait V, Delacroix I, Elharrar B, Vittecoq D, Bolliot C, Lepretre A, Genet P, Masse V, Perrone V, Boussard JL, Chardon P, Froguel E, Simon P, Tassi S, Avettand Fenoel V, Barin F, Bourgeois C, Cardon F, Chaix ML, Delfraissy JF, Essat A, Fischer H, Lecuroux C, Meyer L, Petrov-Sanchez V, Rouzioux C, Saez-Cirion A, Seng R, Kuldanek K, Mullaney S, Young C, Zucchetti A, Bevan MA, McKernan S, Wandolo E, Richardson C, Youssef E, Green P, Faulkner S, Faville R, Herman S, Care C, Blackman H, Bellenger K, Fairbrother K, Phillips A, Babiker A, Delpech V, Fidler S, Clarke M, Fox J, Gilson R, Goldberg D, Hawkins D, Johnson A, Johnson M, McLean K, Nastouli E, Post F, Kennedy N, Pritchard J, Andrady U, Rajda N, Donnelly C, McKernan S, Drake S, Gilleran G, White D, Ross J, Harding J, Faville R, Sweeney J, Flegg P, Toomer S, Wilding H, Woodward R, Dean G, Richardson C, Perry N, Gompels M, Jennings L, Bansaal D, Browing M, Connolly L, Stanley B, Estreich S, Magdy A, O'Mahony C, Fraser P, Jebakumar SPR, David L, Mette R, Summerfield H, Evans M, White C, Robertson R, Lean C, Morris S, Winter A, Faulkner S, Goorney B, Howard L, Fairley I, Stemp C, Short L, Gomez M, Young F, Roberts M, Green S, Sivakumar K, Minton J, Siminoni A, Calderwood J, Greenhough D, DeSouza C, Muthern L, Orkin C, Murphy S, Truvedi M, McLean K, Hawkins D, Higgs C, Moyes A, Antonucci S, McCormack S, Lynn W, Bevan M, Fox J, Teague A, Anderson J, Mguni S, Post F, Campbell L, Mazhude C, Russell H, Gilson R, Carrick G, Ainsworth J, Waters A, Byrne P, Johnson M, Fidler S, Kuldanek K, Mullaney S, Lawlor V, Melville R, Sukthankar A, Thorpe S, Murphy C, Wilkins E, Ahmad S, Green P, Tayal S, Ong E, Meaden J, Riddell L, Loay D, Peacock K, Blackman H, Harindra V, Saeed AM, Allen S, Natarajan U, Williams O, Lacey H, Care C, Bowman C, Herman S, Devendra SV, Wither J, Bridgwood A, Singh G, Bushby S, Kellock D, Young S, Rooney G, Snart B, Currie J, Fitzgerald M, Arumainayyagam J, Chandramani S, Rajamanoharan S, Robinson T, Taylor B, Brewer C, Mayr C, Schmidt W, Speidel A, Strohbach F, Arastéh K, Cordes C, Stündel M, Claus J, Baumgarten A, Carganico A, Ingiliz P, Dupke S, Freiwald M, Rausch M, Moll A, Schleehauf D, Hintsche B, Klausen G, Jessen H, Jessen A, Köppe S, Kreckel P, Schranz D, Fischer K, Schulbin H, Speer M, Glaunsinger T, Wicke T, Bieniek B, Hillenbrand H, Schlote F, Lauenroth-Mai E, Schuler C, Schürmann D, Wesselmann H, Brockmeyer N, Gehring P, Schmalöer D, Hower M, Spornraft-Ragaller P, Häussinger D, Reuter S, Esser S, Markus R, Kreft B, Berzow D, Christl A, Meyer A, Plettenberg A, Stoehr A, Graefe K, Lorenzen T, Adam A, Schewe K, Weitner L, Fenske S, Hansen S, Stellbrink HJ, Wiemer D, Hertling S, Schmidt R, Arbter P, Claus B, Galle P, Jäger H, Jä Gel-Guedes E, Postel N, Fröschl M, Spinner C, Bogner J, Salzberger B, Schölmerich J, Audebert F, Marquardt T, Schaffert A, Schnaitmann E, Trein A, Frietsch B, Müller M, Ulmer A, Detering-Hübner B, Kern P, Schubert F, Dehn G, Schreiber M, Güler C, Gunsenheimer-Bartmeyer B, Schmidt D, Meixenberger K, Bannert N
A highly virulent variant of HIV-1 circulating in the Netherlands.
Science (New York, N.Y.) 2022, 375, 540-545.

Mageau A, Papo T, Ruckly S, Strukov A, van Gysel D, Sacre K, Timsit JF
Survival after COVID-19-associated organ failure among inpatients with systemic lupus erythematosus in France: a nationwide study.
Annals of the Rheumatic Diseases 2022, 81, 569-574.

Labbe V, Contou D, Heming N, Megarbane B, Ait-Oufella H, Boissier F, Carreira S, Robert A, Vivier E, Fejjal M, Doyen D, Monchi M, Preau S, Noel-Savina E, Souweine B, Zucman N, Picos SA, Dres M, Juguet W, Mariotte E, Timsit JF, Turpin M, Razazi K, Gendreau S, Baloul S, Voiriot G, Fartoukh M, Audureau E, Mekontso Dessap A
Comparison of standard prophylactic, intermediate prophylactic and therapeutic anticoagulation in patients with severe COVID-19: protocol for the ANTICOVID multicentre, parallel-group, open-label, randomised controlled trial.
BMJ open 2022, 12, e059383.

Vacheron CH, Lepape A, Savey A, Machut A, Timsit JF, Comparot S, Courno G, Vanhems P, Landel V, Lavigne T, Bailly S, Bettega F, Study Group RR, Maucort-Boulch D, Friggeri A
Attributable Mortality of Ventilator-associated Pneumonia Among COVID-19 Patients.
American Journal of Respiratory and Critical Care Medicine 2022

Szychowiak P, Villageois-Tran K, Patrier J, Timsit JF, Ruppé É
The role of the microbiota in the management of intensive care patients.
Annals of Intensive Care 2022, 12, 3.

Béraud G, Timsit JF, Leleu H
Remdesivir and dexamethasone as tools to relieve hospital care systems stressed by COVID-19: A modelling study on bed resources and budget impact.
PloS One 2022, 17, e0262462.

Flahault C, Vioulac C, Fasse L, Bailly S, Timsit JF, Garrouste-Orgeas M
"A story with gaps": An interpretative phenomenological analysis of ICU survivors' experience.
PloS One 2022, 17, e0264310.

Timsit JF, Wicky PH, de Montmollin E
Treatment of Severe Infections Due to Metallo-Betalactamases Enterobacterales in Critically Ill Patients.
Antibiotics (Basel, Switzerland) 2022, 11, 144.

Tabah A, Lipman J, Barbier F, Buetti N, Timsit JF, On Behalf Of The Escmid Study Group For Infections In Critically Ill Patients-Esgcip n
Use of Antimicrobials for Bloodstream Infections in the Intensive Care Unit, a Clinically Oriented Review.
Antibiotics (Basel, Switzerland) 2022, 11, 362.

2021


Sarton B, Jaquet P, Belkacemi D, de Montmollin E, Bonneville F, Sazio C, Frérou A, Conrad M, Daubin D, Chabanne R, Argaud L, Dailler F, Brulé N, Lerolle N, Maestraggi Q, Marechal J, Bailly P, Razazi K, Mateos F, Guidet B, Levrat A, Susset V, Lautrette A, Mira JP, El Kalioubie A, Robert A, Massri A, Albucher JF, Olivot JM, Conil JM, Boudma L, Timsit JF, Sonneville R, Silva S, EC
Assessment of Magnetic Resonance Imaging Changes and Functional Outcomes Among Adults With Severe Herpes Simplex Encephalitis.
JAMA network open 2021, 4, e2114328.

Buetti N, Souweine B, Mermel L, Mimoz O, Ruckly S, Loiodice A, Mongardon N, Lucet JC, Parienti JJ, Timsit JF
Obesity and risk of catheter-related infections in the ICU. A post hoc analysis of four large randomized controlled trials.
Intensive Care Medicine 2021, 47, 435-443.

Buetti N, Ruckly S, de Montmollin E, Reignier J, Terzi N, Cohen Y, Shiami S, Dupuis C, Timsit JF
COVID-19 increased the risk of ICU-acquired bloodstream infections: a case-cohort study from the multicentric OUTCOMEREA network.
Intensive Care Medicine 2021, 47, 180-187.

Arabi YM, Azoulay E, Al-Dorzi HM, Phua J, Salluh J, Binnie A, Hodgson C, Angus DC, Cecconi M, Du B, Fowler R, Gomersall CD, Horby P, Juffermans NP, Kesecioglu J, Kleinpell RM, Machado FR, Martin GS, Meyfroidt G, Rhodes A, Rowan K, Timsit JF, Vincent JL, Citerio G
How the COVID-19 pandemic will change the future of critical care.
Intensive Care Medicine 2021, 47, 282-291.

Buetti N, Mimoz O, Mongardon N, Parienti JJ, Timsit JF
Ultrasound-guided catheterization and infectious risk in obese ICU patients.
Intensive Care Medicine 2021, 47, 632-634.

Arabi YM, Derde LPG, Timsit JF
How COVID-19 will change the management of other respiratory viral infections.
Intensive Care Medicine 2021

Bohé J, Abidi H, Brunot V, Klich A, Klouche K, Sedillot N, Tchenio X, Quenot JP, Roudaut JB, Mottard N, Thiollière F, Dellamonica J, Wallet F, Souweine B, Lautrette A, Preiser JC, Timsit JF, Vacheron CH, Ait Hssain A, Maucort-Boulch D, CIdlG(SG
Individualised versus conventional glucose control in critically-ill patients: the CONTROLING study-a randomized clinical trial.
Intensive Care Medicine 2021, 47, 1271-1283.

Maataoui N, Chemali L, Patrier J, Tran Dinh A, Le Fèvre L, Lortat-Jacob B, Marzouk M, d'Humières C, Rondinaud E, Ruppé E, Montravers P, Timsit JF, Armand-Lefèvre L
Impact of rapid multiplex PCR on management of antibiotic therapy in COVID-19-positive patients hospitalized in intensive care unit.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2021, 40, 2227-2234.

Maraolo AE, Corcione S, Grossi A, Signori A, Alicino C, Hussein K, Trecarichi EM, Viale P, Timsit JF, Veeraraghavan B, Villegas MV, Rahav G, Daikos GL, Vardakas KZ, Roilides E, Uhlemann AC, Ghafur AK, Mornese Pinna S, Bassetti M, Kohler PP, Giacobbe DR
The Impact of Carbapenem Resistance on Mortality in Patients With Klebsiella Pneumoniae Bloodstream Infection: An Individual Patient Data Meta-Analysis of 1952 Patients.
Infectious Diseases and Therapy 2021

Muff S, Tabah A, Que YA, Timsit JF, Mermel L, Harbarth S, Buetti N
Short-Course Versus Long-Course Systemic Antibiotic Treatment for Uncomplicated Intravascular Catheter-Related Bloodstream Infections due to Gram-Negative Bacteria, Enterococci or Coagulase-Negative Staphylococci: A Systematic Review.
Infectious Diseases and Therapy 2021, 10, 1591-1605.

Boyer A, Timsit JF, Klouche K, Canet E, Phan TN, Bohé J, Rubin S, Orieux A, Lautrette A, Gruson D, Souweine B
Aminoglycosides in Critically Ill Septic Patients With Acute Kidney Injury Receiving Continuous Renal Replacement Therapy: A Multicenter, Observational Study.
Clinical Therapeutics 2021, S0149-2918(21)00206-X.

Boyer A, Timsit JF, Klouche K, Canet E, Phan TN, Bohé J, Rubin S, Orieux A, Lautrette A, Gruson D, Souweine B
Aminoglycosides in Critically Ill Septic Patients With Acute Kidney Injury Receiving Intermittent Hemodialysis: A Multicenter, Observational Study.
Clinical Therapeutics 2021, S0149-2918(21)00210-1.

Buetti N, Marschall J, Timsit JF, Atkinson A, Kronenberg A, Sommerstein R, SCfAR(
Distribution of pathogens and antimicrobial resistance in bacteraemia according to hospitalization duration: a nationwide surveillance study in Switzerland.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, S1198-743X(21)00212-3.

Castan B, Akrich B, Levy-Bachelot L, Amode A, Berthelot A, Mackosso C, Mathis L, Mootien J, Ruimy R, Ruiz F, Timsit JF, Boutoille D
Real-world evaluation of ceftolozane/tazobactam therapy and clinical outcomes in France.
Infectious Diseases Now 2021, S2666-9919(21)00111-1.

Lévy Y, Wiedemann A, Hejblum BP, Durand M, Lefebvre C, Surénaud M, Lacabaratz C, Perreau M, Foucat E, Déchenaud M, Tisserand P, Blengio F, Hivert B, Gauthier M, Cervantes-Gonzalez M, Bachelet D, Laouénan C, Bouadma L, Timsit JF, Yazdanpanah Y, Pantaleo G, Hocini H, Thiébaut R, FCcsg
CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death.
iScience 2021, 24, 102711.

Lepape A, Machut A, Gerbier-Colomban S, Kuczewski E, Rasigade JP, Timsit JF, Vanhems P, Wallet F, Savey A, Friggeri A, RRG
Automated surveillance in French ICUs: is it feasible? Results from a survey in French ICUs participating in a surveillance network.
The Journal of Hospital Infection 2021, 115, 1-4.

de Montmollin E, Faille D, Andrieu V, Ajzenberg N, Timsit JF
Intensified thromboprophylaxis in COVID-19 critically ill patients: Is it enough?.
The Journal of Infection 2021

Ferré VM, Lebourgeois S, Menidjel R, Collin G, Chenane HR, Guindi MO, Yazdanpanah Y, Timsit JF, Charpentier C, Descamps D, Fidouh N, Visseaux B
Decreasing humoral response among healthcare workers up to 4 months after two doses of BNT162b2 vaccine.
The Journal of Infection 2021, S0163-4453(21)00488-6.

Fournier M, Faille D, Dossier A, Mageau A, Nicaise Roland P, Ajzenberg N, Borie R, Bouadma L, Bunel V, Castier Y, Choquet C, Crestani B, Daugas E, Deconinck L, Descamps D, Descamps V, Dieudé P, Ducrocq G, Faucher N, Goulenok T, Guidoux C, Khalil A, Lavallée P, Lescure FX, Lortat-Jacob B, Mal H, Mutuon P, Pellenc Q, Steg PG, Taille C, Timsit JF, Yazdanpanah Y, Papo T, Sacré K
Arterial Thrombotic Events in Adult Inpatients With COVID-19.
Mayo Clinic Proceedings 2021, 96, 295-303.

Wunderink RG, Matsunaga Y, Ariyasu M, Clevenbergh P, Echols R, Kaye KS, Kollef M, Menon A, Pogue JM, Shorr AF, Timsit JF, Zeitlinger M, Nagata TD
Cefiderocol versus high-dose, extended-infusion meropenem for the treatment of Gram-negative nosocomial pneumonia (APEKS-NP): a randomised, double-blind, phase 3, non-inferiority trial.
The Lancet. Infectious Diseases 2021, 21, 213-225.

Flament H, Rouland M, Beaudoin L, Toubal A, Bertrand L, Lebourgeois S, Rousseau C, Soulard P, Gouda Z, Cagninacci L, Monteiro AC, Hurtado-Nedelec M, Luce S, Bailly K, Andrieu M, Saintpierre B, Letourneur F, Jouan Y, Si-Tahar M, Baranek T, Paget C, Boitard C, Vallet-Pichard A, Gautier JF, Ajzenberg N, Terrier B, Pène F, Ghosn J, Lescure X, Yazdanpanah Y, Visseaux B, Descamps D, Timsit JF, Monteiro RC, Lehuen A
Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity.
Nature Immunology 2021, 22, 322-335.

Crawford C, Vanoli E, Decorde B, Lancelot M, Duprat C, Josserand C, Jilesen J, Bouadma L, Timsit JF
Modeling of aerosol transmission of airborne pathogens in ICU rooms of COVID-19 patients with acute respiratory failure.
Scientific Reports 2021, 11, 11778.

de Montmollin E, Timsit JF
How Antibiotics Stewardship Can Be Safely Implemented in Patients with Septic Shock?.
Seminars in Respiratory and Critical Care Medicine 2021, 42, 689-697.

Néant N, Lingas G, Le Hingrat Q, Ghosn J, Engelmann I, Lepiller Q, Gaymard A, Ferré V, Hartard C, Plantier JC, Thibault V, Marlet J, Montes B, Bouiller K, Lescure FX, Timsit JF, Faure E, Poissy J, Chidiac C, Raffi F, Kimmoun A, Etienne M, Richard JC, Tattevin P, Garot D, Le Moing V, Bachelet D, Tardivon C, Duval X, Yazdanpanah Y, Mentré F, Laouénan C, Visseaux B, Guedj J, FCCIaFCSg
Modeling SARS-CoV-2 viral kinetics and association with mortality in hospitalized patients from the French COVID cohort.
Proceedings of the National Academy of Sciences of the United States of America 2021, 118,

Dupuis C, Timsit JF
Antibiotics in the first hour: is there new evidence?.
Expert Review of Anti-Infective Therapy 2021, 19, 45-54.

Buetti N, Patrier J, Le Hingrat Q, Loiodice A, Bouadma L, Visseaux B, Timsit JF
Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection in Blood of Critically Ill Patients.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2021, 72, e690-e691.

Buetti N, Mimoz O, Mermel L, Ruckly S, Mongardon N, Dupuis C, Mira JP, Lucet JC, Mégarbane B, Bailly S, Parienti JJ, Timsit JF
Ultrasound Guidance and Risk for Central Venous Catheter-Related Infections in the Intensive Care Unit: A Post Hoc Analysis of Individual Data of 3 Multicenter Randomized Trials.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2021, 73, e1054-e1061.

Dupuis C, Le Bihan C, Maubon D, Calvet L, Ruckly S, Schwebel C, Bouadma L, Azoulay E, Cornet M, Timsit JF, ESG
Performance of Repeated Measures of (1-3)-β-D-Glucan, Mannan Antigen, and Antimannan Antibodies for the Diagnosis of Invasive Candidiasis in ICU Patients: A Preplanned Ancillary Analysis of the EMPIRICUS Randomized Clinical Trial.
Open Forum Infectious Diseases 2021, 8, ofab080.

Dupuis C, Bouadma L, de Montmollin E, Goldgran-Toledano D, Schwebel C, Reignier J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Grapin K, Laurent V, Buetti N, Gainnier M, Souweine B, Timsit JF
Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia.
Critical Care Explorations 2021, 3, e0329.

de Montmollin E, Schwebel C, Dupuis C, Garrouste-Orgeas M, da Silva D, Azoulay E, Laurent V, Thiéry G, Grinea A, Marcotte G, Oziel J, Gainnier M, Siami S, Reignier J, Sztrymf B, Adrie C, Ruckly S, Sonneville R, Timsit JF
Life Support Limitations in Mechanically Ventilated Stroke Patients.
Critical Care Explorations 2021, 3, e0341.

Flahault C, Trosdorf M, Sonrier M, Vioulac C, Fasse L, Timsit JF, Bailly S, Garrouste-Orgeas M
ICU Survivors Experience of ICU Diaries: An Ancillary Qualitative Analysis of the ICU Diary Study.
Critical Care Explorations 2021, 3, e0384.

Legouy C, Girard-Stein L, Wanono R, de Montmollin E, Vellieux G, Bouadma L, Dupuis C, Abid S, Vinclair C, Ruckly S, Rouvel-Tallec A, d'Ortho MP, Timsit JF, Sonneville R
Association of Standard Electroencephalography Findings With Mortality and Command Following in Mechanically Ventilated Patients Remaining Unresponsive After Sedation Interruption.
Critical Care Medicine 2021, 49, e423-e432.

Kerneis S, Visseaux B, Armand-Lefevre L, Timsit JF
Molecular diagnostic methods for pneumonia: how can they be applied in practice?.
Current Opinion in Infectious Diseases 2021, 34, 118-125.

Tabah A, Buetti N, Barbier F, Timsit JF
Current opinion in management of septic shock due to Gram-negative bacteria.
Current Opinion in Infectious Diseases 2021, 34, 718-727.

Le Hingrat Q, Bouzid D, Choquet C, Laurent O, Lescure FX, Timsit JF, Houhou-Fidouh N, Casalino E, Lucet JC, Descamps D, Visseaux B
Viral epidemiology and SARS-CoV-2 co-infections with other respiratory viruses during the first COVID-19 wave in Paris, France.
Influenza and Other Respiratory Viruses 2021, 15, 425-428.

Mageau A, Aldebert G, Van Gysel D, Papo T, Timsit JF, Sacre K
SARS-CoV-2 infection among inpatients with systemic lupus erythematosus in France: a nationwide epidemiological study.
Annals of the Rheumatic Diseases 2021

Reignier J, Le Gouge A, Lascarrou JB, Annane D, Argaud L, Hourmant Y, Asfar P, Badie J, Nay MA, Botoc NV, Brisard L, Bui HN, Chatellier D, Chauvelot L, Combes A, Cracco C, Darmon M, Das V, Debarre M, Delbove A, Devaquet J, Voicu S, Aissaoui-Balanant N, Dumont LM, Oziel J, Gontier O, Groyer S, Guidet B, Jaber S, Lambiotte F, Leroy C, Letocart P, Madeux B, Maizel J, Martinet O, Martino F, Mercier E, Mira JP, Nseir S, Picard W, Piton G, Plantefeve G, Quenot JP, Renault A, Guérin L, Richecoeur J, Rigaud JP, Schneider F, Silva D, Sirodot M, Souweine B, Reizine F, Tamion F, Terzi N, Thévenin D, Thiéry G, Thieulot-Rolin N, Timsit JF, Tinturier F, Tirot P, Vanderlinden T, Vinatier I, Vinsonneau C, Maugars D, Giraudeau B
Impact of early low-calorie low-protein versus standard-calorie standard-protein feeding on outcomes of ventilated adults with shock: design and conduct of a randomised, controlled, multicentre, open-label, parallel-group trial (NUTRIREA-3).
BMJ open 2021, 11, e045041.

Voiriot G, Fartoukh M, Durand-Zaleski I, Berard L, Rousseau A, Armand-Lefevre L, Verdet C, Argaud L, Klouche K, Megarbane B, Patrier J, Richard JC, Reignier J, Schwebel C, Souweine B, Tandjaoui-Lambiotte Y, Simon T, Timsit JF, MCsg
Combined use of a broad-panel respiratory multiplex PCR and procalcitonin to reduce duration of antibiotics exposure in patients with severe community-acquired pneumonia (MULTI-CAP): a multicentre, parallel-group, open-label, individual randomised trial conducted in French intensive care units.
BMJ open 2021, 11, e048187.

Buetti N, Mimoz O, Schwebel C, Ruckly S, Castry M, Dupuis C, Souweine B, Lucet JC, Timsit JF
Insertion Site and Infection Risk among Peripheral Arterial Catheters.
American Journal of Respiratory and Critical Care Medicine 2021, 203, 630-633.

Dumas G, Lemiale V, Rathi N, Cortegiani A, Pène F, Bonny V, Salluh J, Albaiceta GM, Soares M, Soubani AO, Canet E, Hanane T, Kouatchet A, Mokart D, Lebiedz P, Türkoğlu M, Coudroy R, Jeon K, Demoule A, Mehta S, Caruso P, Frat JP, Yang KY, Roca O, Laffey J, Timsit JF, Azoulay E, Darmon M
Survival in Immunocompromised Patients Ultimately Requiring Invasive Mechanical Ventilation: A Pooled Individual Patient Data Analysis.
American Journal of Respiratory and Critical Care Medicine 2021, 204, 187-196.

Tandjaoui-Lambiotte Y, Timsit JF, Alloui C, Zahar JR, Vanoli E
Viral Dispersion in the Intensive Care Unit: The Wind Effect.
American Journal of Respiratory and Critical Care Medicine 2021

von Cube M, Timsit JF, Kammerlander A, Schumacher M
Quantifying and communicating the burden of COVID-19.
BMC medical research methodology 2021, 21, 164.

Blanc E, Chaize G, Fievez S, Féger C, Herquelot E, Vainchtock A, Timsit JF, Gaillat J
The impact of comorbidities and their stacking on short- and long-term prognosis of patients over 50 with community-acquired pneumonia.
BMC infectious diseases 2021, 21, 949.

Gheerbrant H, Timsit JF, Terzi N, Ruckly S, Laramas M, Levra MG, Jacquet E, Falque L, Moro-Sibilot D, Toffart AC
Factors associated with survival of patients with solid Cancer alive after intensive care unit discharge between 2005 and 2013.
BMC cancer 2021, 21, 9.

Dupuis C, Sabra A, Patrier J, Chaize G, Saighi A, Féger C, Vainchtock A, Gaillat J, Timsit JF
Burden of pneumococcal pneumonia requiring ICU admission in France: 1-year prognosis, resources use, and costs.
Critical Care (London, England) 2021, 25, 24.

Buetti N, Ruckly S, Lucet JC, Mimoz O, Souweine B, Timsit JF
Factors influencing local signs at catheter insertion site regardless of catheter-related bloodstream infections.
Critical Care (London, England) 2021, 25, 71.

Wicky PH, Niedermann MS, Timsit JF
Ventilator-associated pneumonia in the era of COVID-19 pandemic: How common and what is the impact?.
Critical Care (London, England) 2021, 25, 153.

Timsit JF, Huntington JA, Wunderink RG, Shime N, Kollef MH, Kivistik Ü, Nováček M, Réa-Neto Á, Martin-Loeches I, Yu B, Jensen EH, Butterton JR, Wolf DJ, Rhee EG, Bruno CJ
Ceftolozane/tazobactam versus meropenem in patients with ventilated hospital-acquired bacterial pneumonia: subset analysis of the ASPECT-NP randomized, controlled phase 3 trial.
Critical Care (London, England) 2021, 25, 290.

Kollef MH, Shorr AF, Bassetti M, Timsit JF, Micek ST, Michelson AP, Garnacho-Montero J
Timing of antibiotic therapy in the ICU.
Critical Care (London, England) 2021, 25, 360.

Meyer A, Buetti N, Houhou-Fidouh N, Patrier J, Abdel-Nabey M, Jaquet P, Presente S, Girard T, Sayagh F, Ruckly S, Wicky PH, de Montmollin E, Bouadma L, Sonneville R, Descamps D, Timsit JF
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients.
Critical Care (London, England) 2021, 25, 417.

Touchard C, Cartailler J, Vellieux G, de Montmollin E, Jaquet P, Wanono R, Reuter J, Para M, Bouadma L, Timsit JF, d'Ortho MP, Kubis N, Rouvel Tallec A, Sonneville R, DSG
Simplified frontal EEG in adults under veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2021, 11, 76.

Jung B, Le Bihan C, Portales P, Bourgeois N, Vincent T, Lachaud L, Chanques G, Conseil M, Corne P, Massanet P, Timsit JF, Jaber S
Monocyte human leukocyte antigen-DR but not β-D-glucan may help early diagnosing invasive Candida infection in critically ill patients.
Annals of Intensive Care 2021, 11, 129.

Buetti N, Ruckly S, Lucet JC, Mageau A, Dupuis C, Souweine B, Mimoz O, Timsit JF
Practices and intravascular catheter infection during on- and off-hours in critically ill patients.
Annals of Intensive Care 2021, 11, 153.

Farfour E, Dimi S, Chassany O, Fouéré S, Valin N, Timsit J, Ghosn J, Duvivier C, Duracinsky M, Zucman D, Dsg
Trends in asymptomatic STI among HIV-positive MSM and lessons for systematic screening.
PloS One 2021, 16, e0250557.

d'Humières C, Patrier J, Lortat-Jacob B, Tran-Dinh A, Chemali L, Maataoui N, Rondinaud E, Ruppé E, Burdet C, Ruckly S, Montravers P, Timsit JF, Armand-Lefevre L
Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France.
PloS One 2021, 16, e0250728.

Papin G, Bailly S, Dupuis C, Ruckly S, Gainnier M, Argaud L, Azoulay E, Adrie C, Souweine B, Goldgran-Toledano D, Marcotte G, Gros A, Reignier J, Mourvillier B, Forel JM, Sonneville R, Dumenil AS, Darmon M, Garrouste-Orgeas M, Schwebel C, Timsit JF, Osg
Clinical and biological clusters of sepsis patients using hierarchical clustering.
PloS One 2021, 16, e0252793.

Dupuis C, de Montmollin E, Buetti N, Goldgran-Toledano D, Reignier J, Schwebel C, Domitile J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Laurent V, Gainnier M, Souweine B, Timsit JF, Orn
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network.
PloS One 2021, 16, e0255644.

Evrard D, Jurcisin I, Assadi M, Patrier J, Tafani V, Ullmann N, Timsit JF, Montravers P, Barry B, Weiss E, Rozencwajg S
Tracheostomy in COVID-19 acute respiratory distress syndrome patients and follow-up: A parisian bicentric retrospective cohort.
PloS One 2021, 16, e0261024.

Lebourgeois S, Chenane HR, Houhou-Fidouh N, Menidjel R, Ferré VM, Collin G, Benmalek N, Coppée R, Larrouy L, Yazdanpanah Y, Timsit JF, Charpentier C, Descamps D, Visseaux B
Earlier In Vitro Viral Production With SARS-CoV-2 Alpha Than With Beta, Gamma, B, or A.27 Variants.
Frontiers in Cellular and Infection Microbiology 2021, 11, 792202.

Ursino M, Dupuis C, Buetti N, de Montmollin E, Bouadma L, Golgran-Toledano D, Ruckly S, Neuville M, Cohen Y, Mourvillier B, Souweine B, Gainnier M, Laurent V, Terzi N, Shiami S, Reignier J, Alberti C, Timsit JF, On Behalf Of The Outcomerea Study Group n
Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients.
Journal of Clinical Medicine 2021, 10,

2020


Vincent JL, Sakr Y, Singer M, Martin-Loeches I, Machado FR, Marshall JC, Finfer S, Pelosi P, Brazzi L, Aditianingsih D, Timsit JF, Du B, Wittebole X, Máca J, Kannan S, Gorordo-Delsol LA, De Waele JJ, Mehta Y, Bonten MJM, Khanna AK, Kollef M, Human M, Angus DC, EII
Prevalence and Outcomes of Infection Among Patients in Intensive Care Units in 2017.
JAMA 2020, 323, 1478-1487.

Luyt CE, Forel JM, Hajage D, Jaber S, Cayot-Constantin S, Rimmelé T, Coupez E, Lu Q, Diallo MH, Penot-Ragon C, Clavel M, Schwebel C, Timsit JF, Bedos JP, Hauw-Berlemont C, Bourenne J, Mayaux J, Lefrant JY, Mira JP, Combes A, Wolff M, Chastre J, Papazian L, ftPTfHSGREdreVAN
Acyclovir for Mechanically Ventilated Patients With Herpes Simplex Virus Oropharyngeal Reactivation: A Randomized Clinical Trial.
JAMA Internal Medicine 2020, 180, 263.

von Cube M, Schumacher M, Putter H, Timsit JF, van de Velde C, Wolkewitz M
The population-attributable fraction for time-dependent exposures using dynamic prediction and landmarking.
Biometrical Journal. Biometrische Zeitschrift 2020, 62, 583-597.

Heyard R, Timsit JF, Held L, CMc
Validation of discrete time-to-event prediction models in the presence of competing risks.
Biometrical Journal. Biometrische Zeitschrift 2020, 62, 643-657.

Denny KJ, Kumar A, Timsit JF, Laupland KB
Extra-cardiac endovascular infections in the critically ill.
Intensive Care Medicine 2020, 46, 173-181.

Saied WI, Martin-Loeches I, Timsit JF
What is new in non-ventilated ICU-acquired pneumonia?.
Intensive Care Medicine 2020, 46, 488-491.

Tabah A, Bassetti M, Kollef MH, Zahar JR, Paiva JA, Timsit JF, Roberts JA, Schouten J, Giamarellou H, Rello J, De Waele J, Shorr AF, Leone M, Poulakou G, Depuydt P, Garnacho-Montero J
Antimicrobial de-escalation in critically ill patients: a position statement from a task force of the European Society of Intensive Care Medicine (ESICM) and European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Critically Ill Patients Study Group (ESGCIP).
Intensive Care Medicine 2020, 46, 245-265.

Timsit JF, Ruppé E, Barbier F, Tabah A, Bassetti M
Bloodstream infections in critically ill patients: an expert statement.
Intensive Care Medicine 2020, 46, 266-284.

Timsit JF, Lipman J, Bassetti M
Antimicrobial de-escalation is part of appropriate antibiotic usage in ICU.
Intensive Care Medicine 2020, 46, 1039-1042.

Bouadma L, Lescure FX, Lucet JC, Yazdanpanah Y, Timsit JF
Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists.
Intensive Care Medicine 2020, 46, 579-582.

Andremont O, Armand-Lefevre L, Dupuis C, de Montmollin E, Ruckly S, Lucet JC, Smonig R, Magalhaes E, Ruppé E, Mourvillier B, Lebut J, Lermuzeaux M, Sonneville R, Bouadma L, Timsit JF, Cnc
Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.
Intensive Care Medicine 2020, 46, 1232-1242.

Abdul-Aziz MH, Alffenaar JWC, Bassetti M, Bracht H, Dimopoulos G, Marriott D, Neely MN, Paiva JA, Pea F, Sjovall F, Timsit JF, Udy AA, Wicha SG, Zeitlinger M, De Waele JJ, Roberts JA, ISoESoICM(, PaCIPSGoESoCMaID(, IDGoIAoTDMaCT(, IitIaSWGoISoAC(
Antimicrobial therapeutic drug monitoring in critically ill adult patients: a Position Paper.
Intensive Care Medicine 2020, 46, 1127-1153.

De Bus L, Depuydt P, Steen J, Dhaese S, De Smet K, Tabah A, Akova M, Cotta MO, De Pascale G, Dimopoulos G, Fujitani S, Garnacho-Montero J, Leone M, Lipman J, Ostermann M, Paiva JA, Schouten J, Sjövall F, Timsit JF, Roberts JA, Zahar JR, Zand F, Zirpe K, De Waele JJ, Dsg
Antimicrobial de-escalation in the critically ill patient and assessment of clinical cure: the DIANA study.
Intensive Care Medicine 2020, 46, 1404-1417.

Bassetti M, Kollef MH, Timsit JF
Bacterial and fungal superinfections in critically ill patients with COVID-19.
Intensive Care Medicine 2020, 46, 2071-2074.

Kalil AC, Timsit JF
Less is more: critically ill status is not a carte blanche for unlimited antibiotic use.
Intensive Care Medicine 2020, 46, 2075-2078.

Luyt CE, Bouadma L, Morris AC, Dhanani JA, Kollef M, Lipman J, Martin-Loeches I, Nseir S, Ranzani OT, Roquilly A, Schmidt M, Torres A, Timsit JF
Pulmonary infections complicating ARDS.
Intensive Care Medicine 2020, 46, 2168-2183.

Bouadma L, Wiedemann A, Patrier J, Surénaud M, Wicky PH, Foucat E, Diehl JL, Hejblum BP, Sinnah F, de Montmollin E, Lacabaratz C, Thiébaut R, Timsit JF, Lévy Y
Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome.
Journal of Clinical Immunology 2020, 40, 1082-1092.

Sonneville R, Mazighi M, Bresson D, Crassard I, Crozier S, de Montmollin E, Degos V, Faugeras F, Gayat E, Josse L, Lamy C, Magalhaes E, Maldjian A, Ruckly S, Servan J, Vassel P, Vigué B, Timsit JF, Woimant F, Si
Outcomes of Acute Stroke Patients Requiring Mechanical Ventilation: Study Protocol for the SPICE Multicenter Prospective Observational Study.
Neurocritical Care 2020, 32, 624-629.

Magalhaes E, Reuter J, Wanono R, Bouadma L, Jaquet P, Tanaka S, Sinnah F, Ruckly S, Dupuis C, de Montmollin E, Para M, Braham W, Pisani A, d'Ortho MP, Rouvel-Tallec A, Timsit JF, Sonneville R, Dsg
Early EEG for Prognostication Under Venoarterial Extracorporeal Membrane Oxygenation.
Neurocritical Care 2020, 33, 688-694.

Rello J, Belliato M, Dimopoulos MA, Giamarellos-Bourboulis EJ, Jaksic V, Martin-Loeches I, Mporas I, Pelosi P, Poulakou G, Pournaras S, Tamae-Kakazu M, Timsit JF, Waterer G, Tejada S, Dimopoulos G
Update in COVID-19 in the intensive care unit from the 2020 HELLENIC Athens International symposium.
Anaesthesia, Critical Care & Pain Medicine 2020, 39, 723-730.

Michallet M, Sobh M, Deray G, Gangneux JP, Pigneux A, Larrey D, Ribaud P, Mira JP, Nivoix Y, Yakoub-Agha I, Timsit JF, Alfandari S, Herbrecht R
Antifungal Stewardship in Hematology: Reflection of a Multidisciplinary Group of Experts.
Clinical Lymphoma Myeloma and Leukemia 2020, S2152265020304250.

de Grooth HJ, Timsit JF, Mermel L, Mimoz O, Buetti N, du Cheyron D, Oudemans-van Straaten HM, Parienti JJ, 3CaDg
Validity of surrogate endpoints assessing central venous catheter-related infection: evidence from individual- and study-level analyses.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, 26, 563-571.

Peiffer-Smadja N, Lucet JC, Bendjelloul G, Bouadma L, Gerard S, Choquet C, Jacques S, Khalil A, Maisani P, Casalino E, Descamps D, Timsit JF, Yazdanpanah Y, Lescure FX
Challenges and issues about organising a hospital to respond to the COVID-19 outbreak: experience from a French reference centre.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020

Buetti N, Souweine B, Mermel L, Mimoz O, Ruckly S, Loiodice A, Mongardon N, Lucet JC, Parienti JJ, Timsit JF
Concurrent systemic antibiotics at catheter insertion and intravascular catheter-related infection in the ICU: a post hoc analysis using individual data from five large RCTs.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020

Muff S, Hebeisen U, Timsit JF, Mermel L, Harbarth S, Buetti N
Treatment duration of enterococcal intravascular catheter-related infections.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020

Hingrat QL, Visseaux B, Laouenan C, Tubiana S, Bouadma L, Yazdanpanah Y, Duval X, Burdet C, Ichou H, Damond F, Bertine M, Benmalek N, Choquet C, Timsit JF, Ghosn J, Charpentier C, Descamps D, Houhou-Fidouh N, FCcmcCCsg, motFCcsg(ao, motCCsgPi, SC, CCCC, Casa, VL, BC, P, S, G
Detection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, S1198-743X(20)30721-7.

Benchetrit L, Mathy V, Armand-Lefevre L, Bouadma L, Timsit JF
Successful treatment of septic shock due to NDM-1-producing Klebsiella pneumoniae using ceftazidime/avibactam combined with aztreonam in solid organ transplant recipients: report of two cases.
International Journal of Antimicrobial Agents 2020, 55, 105842.

Bailly S, Galerneau LM, Ruckly S, Seiller A, Terzi N, Schwebel C, Dupuis C, Tamisier R, Mourvillier B, Pepin JL, Timsit JF
Impact of obstructive sleep apnea on the obesity paradox in critically ill patients.
Journal of Critical Care 2020, 56, 120-124.

Jolivet S, Lolom I, Bailly S, Bouadma L, Lortat-Jacob B, Montravers P, Armand-Lefevre L, Timsit JF, Lucet JC
Impact of colonization pressure on acquisition of extended-spectrum β-lactamase-producing Enterobacterales and meticillin-resistant Staphylococcus aureus in two intensive care units: a 19-year retrospective surveillance.
The Journal of Hospital Infection 2020, 105, 10-16.

Ibn Saied W, Merceron S, Schwebel C, Le Monnier A, Oziel J, Garrouste-Orgeas M, Marcotte G, Ruckly S, Souweine B, Darmon M, Bouadma L, de Montmollin E, Mourvillier B, Reignier J, Papazian L, Siami S, Azoulay E, Bédos JP, Timsit JF
Ventilator-associated pneumonia due to Stenotrophomonas maltophilia: Risk factors and outcome.
The Journal of Infection 2020, 80, 279-285.

San C, Lê MP, Matheron S, Mourvillier B, Caseris M, Timsit JF, Wolff M, Yazdanpanah Y, Descamps D, Peytavin G
Management of oral antiretroviral administration in patients with swallowing disorders or with an enteral feeding tube.
Medecine Et Maladies Infectieuses 2020, 50, 537-544.

Denis N, Timsit JF, Giaj Levra M, Sakhri L, Duruisseaux M, Schwebel C, Merle P, Pinsolle J, Ferrer L, Moro-Sibilot D, Toffart AC
Impact of systematic advanced care planning in lung cancer patients: A prospective study.
Respiratory Medicine and Research 2020, 77, 11-17.

Lescure FX, Bouadma L, Nguyen D, Parisey M, Wicky PH, Behillil S, Gaymard A, Bouscambert-Duchamp M, Donati F, Le Hingrat Q, Enouf V, Houhou-Fidouh N, Valette M, Mailles A, Lucet JC, Mentre F, Duval X, Descamps D, Malvy D, Timsit JF, Lina B, van-der-Werf S, Yazdanpanah Y
Clinical and virological data of the first cases of COVID-19 in Europe: a case series.
The Lancet. Infectious Diseases 2020, 20, 697-706.

von Cube M, Timsit JF, Schumacher M, Motschall E, Schumacher M
Quantification and interpretation of attributable mortality in core clinical infectious disease journals.
The Lancet. Infectious Diseases 2020, 20, e299-e306.

Lê MP, Jaquet P, Patrier J, Wicky PH, Le Hingrat Q, Veyrier M, Kauv J, Sonneville R, Visseaux B, Laouénan C, Bouadma L, Descamps D, de Montmollin E, Peytavin G, Timsit JF
Pharmacokinetics of lopinavir/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2657-2660.

Reuter J, Peoc'h K, Bouadma L, Ruckly S, Chicha-Cattoir V, Faille D, Bourrienne MC, Dupuis C, Magalhaes E, Tanaka S, Vinclair C, de Montmollin E, Mazighi M, Para M, Braham W, Pisani A, Ajzenberg N, Timsit JF, Sonneville R
Neuron-Specific Enolase Levels in Adults Under Venoarterial Extracorporeal Membrane Oxygenation.
Critical Care Explorations 2020, 2, e0239.

Buetti N, Ruckly S, Lucet JC, Perozziello A, Mimoz O, Souweine B, Timsit JF
The Insertion Site Should Be Considered for the Empirical Therapy of Short-Term Central Venous and Arterial Catheter-Related Infections.
Critical Care Medicine 2020, 48, 739-744.

Baudry G, Sonneville R, Waintraub X, Lebreton G, Deguillard C, Mertens E, Bouadma L, Demondion P, Bréchot N, Luyt CE, Extramiana F, Hékimian G, Dupuis C, Para M, Pisani A, Braham W, Gandjbakhch E, Leenhardt A, Timsit JF, Leprince P, Combes A, Schmidt M
Extracorporeal Membrane Oxygenation to Support Life-Threatening Drug-Refractory Electrical Storm.
Critical Care Medicine 2020, 48, e856-e863.

Buetti N, Tabah A, Timsit JF, Zingg W
What is new in catheter use and catheter infection prevention in the ICU.
Current Opinion in Critical Care 2020, 26, 459-465.

Patrier J, Timsit JF
Carbapenem use in critically ill patients.
Current Opinion in Infectious Diseases 2020, 33, 86-91.

Barbier F, Timsit JF
Risk stratification for multidrug-resistant bacteria in patients with skin and soft tissue infection.
Current Opinion in Infectious Diseases 2020, 33, 137-145.

Le Fevre L, Timsit JF
Duration of antimicrobial therapy for Gram-negative infections.
Current Opinion in Infectious Diseases 2020, 33, 511-516.

Timsit JF, Leverger G, Milpied N, Gachot B
Treatment of invasive fungal infections in intensive care units with micafungin: The MYRIADE study.
Mycoses 2020, 63, 443-451.

Lê MP, Le Hingrat Q, Jaquet P, Wicky PH, Bunel V, Massias L, Visseaux B, Messika J, Descamps D, Mal H, Timsit JF, Peytavin G
Removal of Remdesivir's Metabolite GS-441524 by Hemodialysis in a Double Lung Transplant Recipient with COVID-19.
Antimicrobial Agents and Chemotherapy 2020, 64,

Bailly S, Gautier-Veyret E, Lê MP, Bouadma L, Andremont O, Neuville M, Mourvillier B, Sonneville R, Magalhaes E, Lebut J, Radjou A, Smonig R, Wolff M, Massias L, Dupuis C, Timsit JF
Impact of Loading Dose of Caspofungin in Pharmacokinetic-Pharmacodynamic Target Attainment for Severe Candidiasis Infections in Patients in Intensive Care Units: the CASPOLOAD Study.
Antimicrobial Agents and Chemotherapy 2020, 64, e01545-20.

Lê MP, Le Beller C, Le Hingrat Q, Jaquet P, Wicky PH, Bunel V, Massias L, Visseaux B, Messika J, Descamps D, Mal H, Timsit JF, Peytavin G
Reply to Yan and Muller, "Captisol and GS-704277, but Not GS-441524, Are Credible Mediators of Remdesivir's Nephrotoxicity".
Antimicrobial Agents and Chemotherapy 2020, 64,

Visseaux B, Le Hingrat Q, Collin G, Bouzid D, Lebourgeois S, Le Pluart D, Deconinck L, Lescure FX, Lucet JC, Bouadma L, Timsit JF, Descamps D, Yazdanpanah Y, Casalino E, Houhou-Fidouh N, McAdam AJ
Evaluation of the QIAstat-Dx Respiratory SARS-CoV-2 Panel, the First Rapid Multiplex PCR Commercial Assay for SARS-CoV-2 Detection.
Journal of Clinical Microbiology 2020, 58, e00630-20, /jcm/58/8/JCM.00630-20.atom.

Peiffer-Smadja N, Bouadma L, Mathy V, Allouche K, Patrier J, Reboul M, Montravers P, Timsit JF, Armand-Lefevre L
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia.
Critical Care (London, England) 2020, 24, 366.

Buetti N, Ruckly S, Schwebel C, Mimoz O, Souweine B, Lucet JC, Timsit JF
Chlorhexidine-impregnated sponge versus chlorhexidine gel dressing for short-term intravascular catheters: which one is better?.
Critical Care (London, England) 2020, 24, 458.

Buetti N, Wicky PH, Le Hingrat Q, Ruckly S, Mazzuchelli T, Loiodice A, Trimboli P, Forni Ogna V, de Montmollin E, Bernasconi E, Visseaux B, Timsit JF
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients.
Critical Care (London, England) 2020, 24, 610.

Buetti N, Ruckly S, Lucet JC, Bouadma L, Garrouste-Orgeas M, Schwebel C, Mimoz O, Souweine B, Timsit JF
Local signs at insertion site and catheter-related bloodstream infections: an observational post hoc analysis using individual data of four RCTs.
Critical Care (London, England) 2020, 24, 694.

Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.

OSG, de Montmollin E, Terzi N, Dupuis C, Garrouste-Orgeas M, da Silva D, Darmon M, Laurent V, Thiéry G, Oziel J, Marcotte G, Gainnier M, Siami S, Sztrymf B, Adrie C, Reignier J, Ruckly S, Sonneville R, Timsit JF
One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study.
Annals of Intensive Care 2020, 10, 53.

Buetti N, Ruckly S, Lucet JC, Bouadma L, Schwebel C, Mimoz O, Timsit JF
Ultrasound guidance and risk for intravascular catheter-related infections among peripheral arterial catheters: a post-hoc analysis of two large randomized-controlled trials.
Annals of Intensive Care 2020, 10, 89.

Timsit JF, Baleine J, Bernard L, Calvino-Gunther S, Darmon M, Dellamonica J, Desruennes E, Leone M, Lepape A, Leroy O, Lucet JC, Merchaoui Z, Mimoz O, Misset B, Parienti JJ, Quenot JP, Roch A, Schmidt M, Slama M, Souweine B, Zahar JR, Zingg W, Bodet-Contentin L, Maxime V
Expert consensus-based clinical practice guidelines management of intravascular catheters in the intensive care unit.
Annals of Intensive Care 2020, 10, 118.

Elabbadi A, Pichon J, Visseaux B, Schnuriger A, Bouadma L, Philippot Q, Patrier J, Labbé V, Ruckly S, Fartoukh M, Timsit JF, Voiriot G
Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study).
Annals of Intensive Care 2020, 10, 123.

Dupuis C, Bouadma L, Ruckly S, Perozziello A, Van-Gysel D, Mageau A, Mourvillier B, de Montmollin E, Bailly S, Papin G, Sinnah F, Vinclair C, Abid S, Sonneville R, Timsit JF
Sepsis and septic shock in France: incidences, outcomes and costs of care.
Annals of Intensive Care 2020, 10, 145.

Sonneville R, Smonig R, Dupuis C, Bouadma L, de Montmollin E, Timsit JF
Natural light exposure and delirium in ICU: does the dark side cloud everything?.
Annals of Intensive Care 2020, 10, 25.

Fontaine C, Armand-Lefèvre L, Magnan M, Nazimoudine A, Timsit JF, Ruppé E
Relationship between the composition of the intestinal microbiota and the tracheal and intestinal colonization by opportunistic pathogens in intensive care patients.
PloS One 2020, 15, e0237260.

Bouzid D, Mullaert J, Le Hingrat Q, Laurent O, Duval X, Lescure X, Timsit JF, Descamps D, Montravers P, Choquet C, Lucet JC, Casalino E, Visseaux B, Eisg
Characteristics associated with COVID-19 or other respiratory viruses' infections at a single-center emergency department.
PloS One 2020, 15, e0243261.

Borie R, Savale L, Dossier A, Ghosn J, Taillé C, Visseaux B, Jebreen K, Diallo A, Tesmoingt C, Morer L, Goletto T, Faucher N, Hajouji L, Neukirch C, Phillips M, Stelianides S, Bouadma L, Brosseau S, Ottaviani S, Pluvy J, Le Pluart D, Debray MP, Raynaud-Simon A, Descamps D, Khalil A, Timsit JF, Lescure FX, Descamps V, Papo T, Humbert M, Crestani B, Dieude P, Vicaut E, Zalcman G, B&KBAHCt
Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study.
PloS One 2020, 15, e0243961.

Dang E, Sayagh F, Lê MP, Neuville M, Sinnah F, Timsit JF, Peytavin G
Plasma pharmacokinetics of bedaquiline administered by nasogastric tube in an intensive care unit.
The International Journal of Tuberculosis and Lung Disease: The Official Journal of the International Union Against Tuberculosis and Lung Disease 2020, 24, 110-112.

2019


Garrouste-Orgeas M, Bailly S, Timsit JF
Use of an ICU Diary and Patient Posttraumatic Stress Disorder Symptoms—Reply.
JAMA 2019, 322, 2025.

Garrouste-Orgeas M, Flahault C, Vinatier I, Rigaud JP, Thieulot-Rolin N, Mercier E, Rouget A, Grand H, Lesieur O, Tamion F, Hamidfar R, Renault A, Parmentier-Decrucq E, Monseau Y, Argaud L, Bretonnière C, Lautrette A, Badié J, Boulet E, Floccard B, Forceville X, Kipnis E, Soufir L, Valade S, Bige N, Gaffinel A, Hamzaoui O, Simon G, Thirion M, Bouadma L, Large A, Mira JP, Amdjar-Badidi N, Jourdain M, Jost PH, Maxime V, Santoli F, Ruckly S, Vioulac C, Leborgne MA, Bellalou L, Fasse L, Misset B, Bailly S, Timsit JF
Effect of an ICU Diary on Posttraumatic Stress Disorder Symptoms Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.
JAMA 2019, 322, 229-239.

Heyard R, Timsit J, Essaied WI, Held L, obotCc
Dynamic clinical prediction models for discrete time‐to‐event data with competing risks—A case study on the OUTCOMEREA database.
Biometrical Journal 2019, 61, 514-534.

von Cube M, Schumacher M, Bailly S, Timsit JF, Lepape A, Savey A, Machut A, Wolkewitz M
The population-attributable fraction for time-dependent exposures and competing risks-A discussion on estimands.
Statistics in Medicine 2019, 38, 3880-3895.

Timsit JF, Bassetti M, Cremer O, Daikos G, de Waele J, Kallil A, Kipnis E, Kollef M, Laupland K, Paiva JA, Rodríguez-Baño J, Ruppé É, Salluh J, Taccone FS, Weiss E, Barbier F
Rationalizing antimicrobial therapy in the ICU: a narrative review.
Intensive Care Medicine 2019, 45, 172-189.

Timsit JF, Citerio G, Lavilloniere M, Perner A, Ruckly S, Bakker J, Bassetti M, Benoit D, Curtis JR, Doig GS, Herridge M, Jaber S, Papazian L, Peters MJ, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Azoulay E
Determinants of downloads and citations for articles published in Intensive Care Medicine.
Intensive Care Medicine 2019, 45, 1058-1060.

Pons S, Timsit JF, Ruckly S, Schwebel C, Papazian L, Azoulay E, Reignier J, Zafrani L
Impact of macrolide therapy in critically ill patients with acute respiratory failure: a desirability of outcome ranking analysis to investigate the OUTCOMEREA database.
Intensive Care Medicine 2019

Timsit JF, Sonneville R, Kalil AC, Bassetti M, Ferrer R, Jaber S, Lanternier F, Luyt CE, Machado F, Mikulska M, Papazian L, Pène F, Poulakou G, Viscoli C, Wolff M, Zafrani L, Van Delden C
Diagnostic and therapeutic approach to infectious diseases in solid organ transplant recipients.
Intensive Care Medicine 2019, 45, 573-591.

Martin-Loeches I, Antonelli M, Cuenca-Estrella M, Dimopoulos G, Einav S, De Waele JJ, Garnacho-Montero J, Kanj SS, Machado FR, Montravers P, Sakr Y, Sanguinetti M, Timsit JF, Bassetti M
ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients.
Intensive Care Medicine 2019, 45, 789-805.

Timsit JF, Schwebel C, Styfalova L, Cornet M, Poirier P, Forrestier C, Ruckly S, Jacob MC, Souweine B
Impact of bronchial colonization with Candida spp. on the risk of bacterial ventilator-associated pneumonia in the ICU: the FUNGIBACT prospective cohort study.
Intensive Care Medicine 2019, 45, 834-843.

Blot S, Poulakou G, Timsit JF
Catheter-associated bloodstream infection rates: how low can you go?.
Intensive Care Medicine 2019, 45, 896-897.

Jaquet P, de Montmollin E, Dupuis C, Sazio C, Conrad M, Susset V, Demeret S, Tadie JM, Argaud L, Barbier F, Sarton B, Chabane R, Daubin D, Brulé N, Lerolle N, Alves M, Da Silva D, Kalioubi AE, Silva S, Bailly P, Wolff M, Bouadma L, Timsit JF, Sonneville R, Esg
Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study.
Intensive Care Medicine 2019, 45, 1103-1111.

Buetti N, Ruckly S, Lucet JC, Mimoz O, Souweine B, Timsit JF
Short-term dialysis catheter versus central venous catheter infections in ICU patients: a post hoc analysis of individual data of 4 multi-centric randomized trials.
Intensive Care Medicine 2019

Blot S, Antonelli M, Arvaniti K, Blot K, Creagh-Brown B, de Lange D, De Waele J, Deschepper M, Dikmen Y, Dimopoulos G, Eckmann C, Francois G, Girardis M, Koulenti D, Labeau S, Lipman J, Lipovestky F, Maseda E, Montravers P, Mikstacki A, Paiva JA, Pereyra C, Rello J, Timsit JF, Vogelaers D, ASS(gobotTGotESoICM
Epidemiology of intra-abdominal infection and sepsis in critically ill patients: "AbSeS", a multinational observational cohort study and ESICM Trials Group Project.
Intensive Care Medicine 2019, 45, 1703-1717.

Mageau A, Timsit JF, Perrozziello A, Ruckly S, Dupuis C, Bouadma L, Papo T, Sacre K
The burden of chronic kidney disease in systemic lupus erythematosus: A nationwide epidemiologic study.
Autoimmunity Reviews 2019, 18, 733-737.

Schweitzer VA, van Werkhoven CH, Rodríguez Baño J, Bielicki J, Harbarth S, Hulscher M, Huttner B, Islam J, Little P, Pulcini C, Savoldi A, Tacconelli E, Timsit JF, van Smeden M, Wolkewitz M, Bonten MJM, Walker AS, Llewelyn MJ, JPIoAR(WGoDoASE
Optimizing design of research to evaluate antibiotic stewardship interventions: consensus recommendations of a multinational working group.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019

Martin-Loeches I, Timsit JF, Leone M, de Waele J, Sartelli M, Kerrigan S, Azevedo LCP, Einav S
Clinical controversies in abdominal sepsis. Insights for critical care settings.
Journal of Critical Care 2019, 53, 53-58.

Mageau A, Sacré K, Perozziello A, Ruckly S, Dupuis C, Bouadma L, Papo T, Timsit JF
Septic shock among patients with systemic lupus erythematosus: short and long-term outcome. Analysis of a French nationwide database.
The Journal of Infection 2019

de Montmollin E, Ruckly S, Schwebel C, Philippart F, Adrie C, Mariotte E, Marcotte G, Cohen Y, Sztrymf B, da Silva D, Bruneel F, Gainnier M, Garrouste-Orgeas M, Sonneville R, Timsit JF, OSG
Pneumonia in acute ischemic stroke patients requiring invasive ventilation: Impact on short and long-term outcomes.
The Journal of Infection 2019, 79, 220-227.

Lattuca-Truc M, Timsit JF, Levra MG, Ruckly S, Villa J, Dumas I, Pinsolle J, Ferrer L, Guillem P, Moro-Sibilot D, Toffart AC
Trends in response rate and survival in small-cell lung cancer patients between 1997 and 2017.
Lung Cancer 2019, 131, 122-127.

Kollef MH, Nováček M, Kivistik Ü, Réa-Neto Á, Shime N, Martin-Loeches I, Timsit JF, Wunderink RG, Bruno CJ, Huntington JA, Lin G, Yu B, Butterton JR, Rhee EG
Ceftolozane-tazobactam versus meropenem for treatment of nosocomial pneumonia (ASPECT-NP): a randomised, controlled, double-blind, phase 3, non-inferiority trial.
The Lancet. Infectious Diseases 2019

Birgand G, Azevedo C, Rukly S, Pissard-Gibollet R, Toupet G, Timsit JF, Lucet JC, tASG
Motion-capture system to assess intraoperative staff movements and door openings: Impact on surrogates of the infectious risk in surgery.
Infection Control & Hospital Epidemiology 2019, 40, 566-573.

Buetti N, Timsit JF
Management and Prevention of Central Venous Catheter-Related Infections in the ICU.
Seminars in Respiratory and Critical Care Medicine 2019, 40, 508-523.

Weiss E, Zahar JR, Alder J, Asehnoune K, Bassetti M, Bonten MJM, Chastre J, De Waele J, Dimopoulos G, Eggimann P, Engelhardt M, Ewig S, Kollef M, Lipman J, Luna C, Martin-Loeches I, Pagani L, Palmer LB, Papazian L, Poulakou G, Prokocimer P, Rello J, Rex JH, Shorr AF, Talbot GH, Thamlikitkul V, Torres A, Wunderink RG, Timsit JF
Elaboration of Consensus Clinical Endpoints to Evaluate Antimicrobial Treatment Efficacy in Future Hospital-acquired/Ventilator-associated Bacterial Pneumonia Clinical Trials.
Clinical Infectious Diseases 2019, 69, 1912-1918.

Bertrand PM, Pereira B, Adda M, Timsit JF, Wolff M, Hilbert G, Gruson D, Garrouste-Orgeas M, Argaud L, Constantin JM, Chabanne R, Quenot JP, Bohe J, Guerin C, Papazian L, Jonquet O, Klouche K, Delahaye A, Riu B, Zieleskiewicz L, Darmon M, Azoulay E, Souweine B, Lautrette A
Disagreement Between Clinicians and Score in Decision-Making Capacity of Critically Ill Patients*:.
Critical Care Medicine 2019, 47, 337-344.

Ibn Saied W, Mourvillier B, Cohen Y, Ruckly S, Reignier J, Marcotte G, Siami S, Bouadma L, Darmon M, de Montmollin E, Argaud L, Kallel H, Garrouste-Orgeas M, Soufir L, Schwebel C, Souweine B, Glodgran-Toledano D, Papazian L, Timsit JF
A Comparison of the Mortality Risk Associated With Ventilator-Acquired Bacterial Pneumonia and Nonventilator ICU-Acquired Bacterial Pneumonia*:.
Critical Care Medicine 2019, 47, 345-352.

Leverger G, Timsit JF, Milpied N, Gachot B
Use of Micafungin for the Prevention and Treatment of Invasive Fungal Infections in Everyday Pediatric Care in France: Results of the MYRIADE Study.
The Pediatric Infectious Disease Journal 2019, 38, 716-721.

Garnacho-Montero J, Timsit JF
Managing Acinetobacter baumannii infections:.
Current Opinion in Infectious Diseases 2019, 32, 69-76.

Bassetti M, Scudeller L, Giacobbe DR, Lamoth F, Righi E, Zuccaro V, Grecchi C, Rebuffi C, Akova M, Alastruey-Izquierdo A, Arikan-Akdagli S, Azoulay E, Blot SI, Cornely OA, Lass-Flörl C, Koehler P, Cuenca-Estrella M, de Lange DW, De Rosa FG, De Waele JJ, Dimopoulos G, Garnacho-Montero J, Hoenigl M, Kanj SS, Maertens J, Martin-Loeches I, Muñoz P, Kullberg BJ, Agvald-Ohman C, Poulakou G, Rello J, Sanguinetti M, Taccone FS, Timsit JF, Torres A, Vazquez JA, Calandra T, ftSGfIiCIP(atFISG(otESoCMaID(, ESoICM(, ECoMM(, MSGEaRC(
Developing definitions for invasive fungal diseases in critically ill adult patients in intensive care units. Protocol of the FUNgal infections Definitions in ICU patients (FUNDICU) project.
Mycoses 2019, 62, 310-319.

Boisson M, Corbi P, Kerforne T, Camilleri L, Debauchez M, Demondion P, Eljezi V, Flecher E, Lepelletier D, Leprince P, Nesseler N, Nizou JY, Roussel JC, Rozec B, Ruckly S, Lucet JC, Timsit JF, Mimoz O
Multicentre, open-label, randomised, controlled clinical trial comparing 2% chlorhexidine-70% isopropanol and 5% povidone iodine-69% ethanol for skin antisepsis in reducing surgical-site infection after cardiac surgery: the CLEAN 2 study protocol.
BMJ open 2019, 9, e026929.

Garrouste-Orgeas M, Flahault C, Poulain E, Evin A, Guirimand F, Fossez-Diaz V, Perruchio S, Verlaine C, Vanbésien A, Kaczmarek W, Birkui de Francqueville L, De Larivière E, Bouquet G, Copel L, Verliac V, Marché V, Mathias C, Gracia D, Mhalla A, Michonneau-Gandon V, Poupardin C, Touzet L, Ranchou G, Guastella V, Richard B, Bienfait F, Sonrier M, Michel D, Ruckly S, Bailly S, Timsit JF
The Fami-life study: protocol of a prospective observational multicenter mixed study of psychological consequences of grieving relatives in French palliative care units on behalf of the family research in palliative care (F.R.I.P.C research network).
BMC Palliative Care 2019, 18, 111.

Bassetti M, Giacobbe DR, Vena A, Trucchi C, Ansaldi F, Antonelli M, Adamkova V, Alicino C, Almyroudi MP, Atchade E, Azzini AM, Carannante N, Carnelutti A, Corcione S, Cortegiani A, Dimopoulos G, Dubler S, García-Garmendia JL, Girardis M, Cornely OA, Ianniruberto S, Kullberg BJ, Lagrou K, Le Bihan C, Luzzati R, Malbrain MLNG, Merelli M, Marques AJ, Martin-Loeches I, Mesini A, Paiva JA, Peghin M, Raineri SM, Rautemaa-Richardson R, Schouten J, Brugnaro P, Spapen H, Tasioudis P, Timsit JF, Tisa V, Tumbarello M, van den Berg CHSB, Veber B, Venditti M, Voiriot G, Wauters J, Montravers P
Incidence and outcome of invasive candidiasis in intensive care units (ICUs) in Europe: results of the EUCANDICU project.
Critical Care 2019, 23,

Morvan AC, Garrouste-Orgeas M, Ruckly S, Forel JM, Argaud L, Rimmelé T, Bedos JP, Azoulay E, Dupuis C, Mourvillier B, Schwebel C, Timsit JF
Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care—an analysis of the OUTCOMEREA database.
Critical Care 2019, 23, 307.

Bouadma L, Darmon M, Argaud L, Vinclair C, Siami S, Garrouste-Orgeas M, Papazian L, Cohen Y, Marcotte G, Styfalova L, Reignier J, Lautrette A, Schwebel C, Timsit JF
Influence of dyskalemia at admission and early dyskalemia correction on survival and cardiac events of critically ill patients.
Critical Care 2019, 23,

Pons S, Sonneville R, Bouadma L, Styfalova L, Ruckly S, Neuville M, Radjou A, Lebut J, Dilly MP, Mourvillier B, Dorent R, Nataf P, Wolff M, Timsit JF
Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation.
Annals of Intensive Care 2019, 9, 17.

Karpanen TJ, Casey AL, Whitehouse T, Timsit JF, Mimoz O, Palomar M, Elliott TSJ
A clinical evaluation of two central venous catheter stabilization systems.
Annals of Intensive Care 2019, 9, 49.

Smonig R, Magalhaes E, Bouadma L, Andremont O, de Montmollin E, Essardy F, Mourvillier B, Lebut J, Dupuis C, Neuville M, Lermuzeaux M, Timsit JF, Sonneville R
Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study.
Annals of Intensive Care 2019, 9, 120.

2018


Bluhmki T, Allignol A, Ruckly S, Timsit JF, Wolkewitz M, Beyersmann J
Estimation of adjusted expected excess length-of-stay associated with ventilation-acquired pneumonia in intensive care: A multistate approach accounting for time-dependent mechanical ventilation.
Biometrical Journal. Biometrische Zeitschrift 2018, 60, 1135-1150.

Bailly S, Meyfroidt G, Timsit JF
What's new in ICU in 2050: big data and machine learning.
Intensive Care Medicine 2018, 44, 1524-1527.

De Waele JJ, Akova M, Antonelli M, Canton R, Carlet J, De Backer D, Dimopoulos G, Garnacho-Montero J, Kesecioglu J, Lipman J, Mer M, Paiva JA, Poljak M, Roberts JA, Rodriguez Bano J, Timsit JF, Zahar JR, Bassetti M
Antimicrobial resistance and antibiotic stewardship programs in the ICU: insistence and persistence in the fight against resistance. A position statement from ESICM/ESCMID/WAAAR round table on multi-drug resistance.
Intensive Care Medicine 2018, 44, 189-196.

La Combe B, Bleibtreu A, Messika J, Fernandes R, Clermont O, Branger C, Billard-Pomares T, Barnaud G, Magdoud F, Eveillard M, Kouatchet A, Lasocki S, Asfar P, Corvec S, Lakhal K, Armand-Lefevre L, Wolff M, Timsit JF, Bourdon S, Reignier J, Martin S, Fihman V, de Prost N, Bador J, Charles PE, Goret J, Boyer A, Wallet F, Jaillette E, Nseir S, Landraud L, Ruimy R, Danin PE, Dellamonica J, Cremniter J, Frat JP, Jauréguy F, Clec'h C, Decré D, Maury E, Dreyfuss D, Denamur E, Ricard JD
Decreased susceptibility to chlorhexidine affects a quarter of Escherichia coli isolates responsible for pneumonia in ICU patients.
Intensive Care Medicine 2018, 44, 531-533.

von Cube MK, Timsit JF, Sommer H, Darmon M, Schwebel C, Bailly S, Souweine B, Wolkewitz M
Relative risk and population-attributable fraction of ICU death caused by susceptible and resistant Pseudomonas aeruginosa ventilator-associated pneumonia: a competing risks approach to investigate the OUTCOMEREA database.
Intensive Care Medicine 2018, 44, 1177-1179.

Barbier F, Bailly S, Schwebel C, Papazian L, Azoulay É, Kallel H, Siami S, Argaud L, Marcotte G, Misset B, Reignier J, Darmon M, Zahar JR, Goldgran-Toledano D, de Montmollin É, Souweine B, Mourvillier B, Timsit JF, OSG
Infection-related ventilator-associated complications in ICU patients colonised with extended-spectrum β-lactamase-producing Enterobacteriaceae.
Intensive Care Medicine 2018

Timsit JF, Bassetti M
Antipathy against SDD is justified: Yes.
Intensive Care Medicine 2018

Azoulay E, Lemiale V, Mourvillier B, Garrouste-Orgeas M, Schwebel C, Ruckly S, Argaud L, Cohen Y, Souweine B, Papazian L, Reignier J, Marcotte G, Siami S, Kallel H, Darmon M, Timsit JF, OSG
Management and outcomes of acute respiratory distress syndrome patients with and without comorbid conditions.
Intensive Care Medicine 2018

Timsit JF, Rupp M, Bouza E, Chopra V, Kärpänen T, Laupland K, Lisboa T, Mermel L, Mimoz O, Parienti JJ, Poulakou G, Souweine B, Zingg W
A state of the art review on optimal practices to prevent, recognize, and manage complications associated with intravascular devices in the critically ill.
Intensive Care Medicine 2018, 44, 742-759.

Puntillo KA, Max A, Timsit JF, Ruckly S, Chanques G, Robleda G, Roche-Campo F, Mancebo J, Divatia JV, Soares M, Ionescu DC, Grintescu IM, Maggiore SM, Rusinova K, Owczuk R, Egerod I, Papathanassoglou EDE, Kyranou M, Joynt GM, Burghi G, Freebairn RC, Ho KM, Kaarlola A, Gerritsen RT, Kesecioglu J, Sulaj MMS, Norrenberg M, Benoit DD, Seha MSG, Hennein A, Pereira FJ, Benbenishty JS, Abroug F, Aquilina A, Monte JRC, An Y, Azoulay E
Pain distress: the negative emotion associated with procedures in ICU patients.
Intensive Care Medicine 2018, 44, 1493-1501.

Timsit JF, Ruppe E, Ferrer R
Focus on sepsis: new concepts and findings in sepsis care.
Intensive Care Medicine 2018, 44, 1997-1999.

Timsit JF, Aboab J, Parienti JJ
Is research from databases reliable? Yes.
Intensive Care Medicine 2018

Garrouste-Orgeas M, Azoulay E, Ruckly S, Schwebel C, de Montmollin E, Bedos JP, Souweine B, Marcotte G, Adrie C, Goldgran-Toledano D, Dumenil AS, Kallel H, Jamali S, Argaud L, Darmon M, Zahar JR, Timsit JF
Diabetes was the only comorbid condition associated with mortality of invasive pneumococcal infection in ICU patients: a multicenter observational study from the Outcomerea research group.
Infection 2018, 46, 669-677.

Ruppé E, Martin-Loeches I, Rouzé A, Levast B, Ferry T, Timsit JF
What's new in restoring the gut microbiota in ICU patients? Potential role of faecal microbiota transplantation.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2018, 24, 803-805.

Annane D, Renault A, Brun-Buisson C, Megarbane B, Quenot JP, Siami S, Cariou A, Forceville X, Schwebel C, Martin C, Timsit JF, Misset B, Ali Benali M, Colin G, Souweine B, Asehnoune K, Mercier E, Chimot L, Charpentier C, François B, Boulain T, Petitpas F, Constantin JM, Dhonneur G, Baudin F, Combes A, Bohé J, Loriferne JF, Amathieu R, Cook F, Slama M, Leroy O, Capellier G, Dargent A, Hissem T, Maxime V, Bellissant E, CTN
Hydrocortisone plus Fludrocortisone for Adults with Septic Shock.
The New England Journal of Medicine 2018, 378, 809-818.

de Kraker MEA, Sommer H, de Velde F, Gravestock I, Weiss E, McAleenan A, Nikolakopoulos S, Amit O, Ashton T, Beyersmann J, Held L, Lovering AM, MacGowan AP, Mouton JW, Timsit JF, Wilson D, Wolkewitz M, Bettiol E, Dane A, Harbarth S, CNC
Optimizing the Design and Analysis of Clinical Trials for Antibacterials Against Multidrug-resistant Organisms: A White Paper From COMBACTE's STAT-Net.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018, 67, 1922-1931.

Zahar JR, Blot S, Nordmann P, Martischang R, Timsit JF, Harbarth S, Barbier F
Screening for intestinal carriage of ESBL-producing Enterobacteriaceae in critically ill patients: expected benefits and evidence-based controversies.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018

Dananché C, Vanhems P, Machut A, Aupée M, Bervas C, L'Hériteau F, Lepape A, Lucet JC, Stoeckel V, Timsit JF, Berger-Carbonne A, Savey A, Bénet T, HAI(SNoI(RR
Trends of Incidence and Risk Factors of Ventilator-Associated Pneumonia in Elderly Patients Admitted to French ICUs Between 2007 and 2014.
Critical Care Medicine 2018, 46, 869-877.

Sommer H, Timsit JF, von Cube M, Schumacher M, Darmon M, Schwebel C, Ruckly S, Wolkewitz M, CMC
The Impact of Early Adequate Treatment on Extubation and Discharge Alive of Patients With Pseudomonas aeruginosa-Related Ventilator-Associated Pneumonia.
Critical Care Medicine 2018, 46, 1643-1648.

Gros A, Dupuis C, Ruckly S, Lautrette A, Garrouste-Orgeas M, Gainnier M, Forel JM, Marcotte G, Azoulay E, Cohen Y, Schwebel C, Argaud L, de Montmollin E, Siami S, Goldgran-Toledano D, Darmon M, Timsit JF, OSG
Association Between Body Weight Variation and Survival and Other Adverse Events in Critically Ill Patients With Shock: A Multicenter Cohort Study of the OUTCOMEREA Network.
Critical Care Medicine 2018, 46, e981-e987.

Cantier M, Morisot A, Guérot E, Megarbane B, Razazi K, Contou D, Mariotte E, Canet E, De Montmollin E, Dubée V, Boulet E, Gaudry S, Voiriot G, Mayaux J, Pène F, Neuville M, Mourvillier B, Ruckly S, Bouadma L, Wolff M, Timsit JF, Sonneville R, Esg
Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study.
Critical Care (London, England) 2018, 22, 210.

Truche AS, Ragey SP, Souweine B, Bailly S, Zafrani L, Bouadma L, Clec'h C, Garrouste-Orgeas M, Lacave G, Schwebel C, Guebre-Egziabher F, Adrie C, Dumenil AS, Zaoui P, Argaud L, Jamali S, Goldran Toledano D, Marcotte G, Timsit JF, Darmon M
ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients.
Annals of Intensive Care 2018, 8, 127.

Madhi F, Jung C, Timsit S, Levy C, Biscardi S, Lorrot M, Grimprel E, Hees L, Craiu I, Galerne A, Dubos F, Cixous E, Hentgen V, Béchet S, UtIdtESBlEiCG, Bonacorsi S, Cohen R
Febrile urinary-tract infection due to extended-spectrum beta-lactamase-producing Enterobacteriaceae in children: A French prospective multicenter study.
PloS One 2018, 13, e0190910.

Poncin T, Fouere S, Braille A, Camelena F, Agsous M, Bebear C, Kumanski S, Lot F, Mercier-Delarue S, Ngangro NN, Salmona M, Schnepf N, Timsit J, Unemo M, Bercot B
Multidrug-resistant Neisseria gonorrhoeae failing treatment with ceftriaxone and doxycycline in France, November 2017.
Euro Surveillance: Bulletin Europeen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin 2018, 23,

Gangneux JP, Cornet M, Bailly S, Fradin C, Féger C, Timsit JF, Leroy O, Sendid B, Bougnoux ME
Clinical Impact of Antifungal Susceptibility, Biofilm Formation and Mannoside Expression of Candida Yeasts on the Outcome of Invasive Candidiasis in ICU: An Ancillary Study on the Prospective AmarCAND2 Cohort.
Frontiers in Microbiology 2018, 9, 2907.

2017


Sonneville R, Gimenez L, Labreuche J, Smonig R, Magalhaes E, Bouadma L, Timsit JF, Mazighi M
What is the prognosis of acute stroke patients requiring ICU admission?.
Intensive Care Medicine 2017, 43, 271-272.

Bassetti M, Garnacho-Montero J, Calandra T, Kullberg B, Dimopoulos G, Azoulay E, Chakrabarti A, Kett D, Leon C, Ostrosky-Zeichner L, Sanguinetti M, Timsit JF, Richardson MD, Shorr A, Cornely OA
Intensive care medicine research agenda on invasive fungal infection in critically ill patients.
Intensive Care Medicine 2017, 43, 1225-1238.

Poulakou G, Matthaiou DK, Bassetti M, Erdem H, Dimopoulos G, Curcio DJ, Carlet J, Lipman J, Timsit JF, Giamarellou H, Arfaras-Melainis A, Rello J, EI
"Salvage treatment" for infections by extensively- and pan-drug-resistant pathogens is common and often sub-optimal.
Intensive Care Medicine 2017, 43, 1164-1166.

Timsit JF, de Kraker MEA, Sommer H, Weiss E, Bettiol E, Wolkewitz M, Nikolakopoulos S, Wilson D, Harbarth S, CNc
Appropriate endpoints for evaluation of new antibiotic therapies for severe infections: a perspective from COMBACTE's STAT-Net.
Intensive Care Medicine 2017, 43, 1002-1012.

Sonneville R, de Montmollin E, Poujade J, Garrouste-Orgeas M, Souweine B, Darmon M, Mariotte E, Argaud L, Barbier F, Goldgran-Toledano D, Marcotte G, Dumenil AS, Jamali S, Lacave G, Ruckly S, Mourvillier B, Timsit JF
Potentially modifiable factors contributing to sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1075-1084.

Perner A, Gordon AC, Angus DC, Lamontagne F, Machado F, Russell JA, Timsit JF, Marshall JC, Myburgh J, Shankar-Hari M, Singer M
The intensive care medicine research agenda on septic shock.
Intensive Care Medicine 2017, 43, 1294-1305.

Laupland KB, Paiva JA, Timsit JF
Focus on severe infections.
Intensive Care Medicine 2017, 43, 1033-1036.

Yamaga S, Shime N, Sonneville R, de Montmollin E, Timsit JF
Risk factors for sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1548-1549.

Montravers P, Perrigault PF, Timsit JF, Mira JP, Lortholary O, Leroy O, Gangneux JP, Guillemot D, Bensoussan C, Bailly S, Azoulay E, Constantin JM, Dupont H, ASG
Antifungal therapy for patients with proven or suspected Candida peritonitis: Amarcand2, a prospective cohort study in French intensive care units.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2017, 23, 117.e1-117.e8.

Bleibtreu A, Arias P, Vallois D, Debit A, Lermuzeaux M, Rioux C, Cabras O, Lucet JC, Choquet C, Timsit JF, Yazdanpanah Y, Lescure FX
Delayed management of Staphyloccocus aureus infective endocarditis in a Middle East respiratory syndrome coronavirus possible case hospitalized in 2015 in Paris, France.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2017, 23, 416-417.

Zahar JR, Lesprit P, Ruckly S, Eden A, Hikombo H, Bernard L, Harbarth S, Timsit JF, Brun-Buisson C, BSG
Predominance of healthcare-associated cases among episodes of community-onset bacteraemia due to extended-spectrum β-lactamase-producing Enterobacteriaceae.
International Journal of Antimicrobial Agents 2017, 49, 67-73.

Zahar JR, Lesprit P, Ruckly S, Eden A, Hikombo H, Bernard L, Harbarth S, Timsit JF, Brun-Buisson C, BSG
Erratum to 'Predominance of healthcare-associated cases among episodes of community-onset bacteraemia due to extended-spectrum β-lactamase-producing Enterobacteriaceae' [International Journal of Antimicrobial Agents 49/1 67-73].
International Journal of Antimicrobial Agents 2017, 49, 480-481.

Bailly S, Leroy O, Dupont H, Timsit JF
Secondarily documented invasive candidiasis is unpredictable using traditional risk factors in non transplant - non-neutropenic adult ICU patients.
International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases 2017, 54, 31-33.

Loubet P, Voiriot G, Houhou-Fidouh N, Neuville M, Bouadma L, Lescure FX, Descamps D, Timsit JF, Yazdanpanah Y, Visseaux B
Impact of respiratory viruses in hospital-acquired pneumonia in the intensive care unit: A single-center retrospective study.
Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology 2017, 91, 52-57.

Adrie C, Garrouste-Orgeas M, Ibn Essaied W, Schwebel C, Darmon M, Mourvillier B, Ruckly S, Dumenil AS, Kallel H, Argaud L, Marcotte G, Barbier F, Laurent V, Goldgran-Toledano D, Clec'h C, Azoulay E, Souweine B, Timsit JF, OSG
Attributable mortality of ICU-acquired bloodstream infections: Impact of the source, causative micro-organism, resistance profile and antimicrobial therapy.
The Journal of Infection 2017, 74, 131-141.

Bailly S, Leroy O, Azoulay E, Montravers P, Constantin JM, Dupont H, Guillemot D, Lortholary O, Mira JP, Perrigault PF, Gangneux JP, Timsit JF, ASG
Impact of echinocandin on prognosis of proven invasive candidiasis in ICU: A post-hoc causal inference model using the AmarCAND2 study.
The Journal of Infection 2017, 74, 408-417.

Baldesi O, Bailly S, Ruckly S, Lepape A, L'Heriteau F, Aupee M, Boussat S, Bervas C, Machut A, Berger-Carbonne A, Savey A, Timsit JF, RRn
ICU-acquired candidaemia in France: Epidemiology and temporal trends, 2004-2013 - A study from the REA-RAISIN network.
The Journal of Infection 2017, 75, 59-67.

Timsit JF, Pilmis B, Zahar JR
How Should We Treat Hospital-Acquired and Ventilator-Associated Pneumonia Caused by Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae?.
Seminars in Respiratory and Critical Care Medicine 2017, 38, 287-300.

Jullien V, Azoulay E, Schwebel C, Le Saux T, Charles PE, Cornet M, Souweine B, Klouche K, Jaber S, Trouillet JL, Bruneel F, Cour M, Cousson J, Meziani F, Gruson D, Paris A, Darmon M, Garrouste-Orgeas M, Navellou JC, Foucrier A, Allaouchiche B, Das V, Gangneux JP, Ruckly S, Wolff M, Timsit JF, ETSG
Population pharmacokinetics of micafungin in ICU patients with sepsis and mechanical ventilation.
The Journal of Antimicrobial Chemotherapy 2017, 72, 181-189.

Dupuis C, Garrouste-Orgeas M, Bailly S, Adrie C, Goldgran-Toledano D, Azoulay E, Ruckly S, Marcotte G, Souweine B, Darmon M, Cohen Y, Schwebel C, Lacave G, Bouadma L, Timsit JF, OSG
Effect of Transfusion on Mortality and Other Adverse Events Among Critically Ill Septic Patients: An Observational Study Using a Marginal Structural Cox Model.
Critical Care Medicine 2017, 45, 1972-1980.

de Montmollin E, Demeret S, Brulé N, Conrad M, Dailler F, Lerolle N, Navellou JC, Schwebel C, Alves M, Cour M, Engrand N, Tonnelier JM, Maury E, Ruckly S, Picard G, Rogemond V, Magalhaes É, Sharshar T, Timsit JF, Honnorat J, Sonneville R, ESG‡
Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.
American Journal of Respiratory and Critical Care Medicine 2017, 195, 491-499.

Torres A, Niederman MS, Chastre J, Ewig S, Fernandez-Vandellos P, Hanberger H, Kollef M, Li Bassi G, Luna CM, Martin-Loeches I, Paiva JA, Read RC, Rigau D, Timsit JF, Welte T, Wunderink R
International ERS/ESICM/ESCMID/ALAT guidelines for the management of hospital-acquired pneumonia and ventilator-associated pneumonia: Guidelines for the management of hospital-acquired pneumonia (HAP)/ventilator-associated pneumonia (VAP) of the European Respiratory Society (ERS), European Society of Intensive Care Medicine (ESICM), European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and Asociación Latinoamericana del Tórax (ALAT).
The European Respiratory Journal 2017, 50,

Viglino D, Vesin A, Ruckly S, Morelli X, Slama R, Debaty G, Danel V, Maignan M, Timsit JF
Daily volume of cases in emergency call centers: construction and validation of a predictive model.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2017, 25, 86.

Weiss E, Essaied W, Adrie C, Zahar JR, Timsit JF
Treatment of severe hospital-acquired and ventilator-associated pneumonia: a systematic review of inclusion and judgment criteria used in randomized controlled trials.
Critical Care (London, England) 2017, 21, 162.

Terzi N, Darmon M, Reignier J, Ruckly S, Garrouste-Orgeas M, Lautrette A, Azoulay E, Mourvillier B, Argaud L, Papazian L, Gainnier M, Goldgran-Toledano D, Jamali S, Dumenil AS, Schwebel C, Timsit JF, Osg
Initial nutritional management during noninvasive ventilation and outcomes: a retrospective cohort study.
Critical Care (London, England) 2017, 21, 293.

Garrouste-Orgeas M, Flahault C, Fasse L, Ruckly S, Amdjar-Badidi N, Argaud L, Badie J, Bazire A, Bige N, Boulet E, Bouadma L, Bretonnière C, Floccard B, Gaffinel A, de Forceville X, Grand H, Halidfar R, Hamzaoui O, Jourdain M, Jost PH, Kipnis E, Large A, Lautrette A, Lesieur O, Maxime V, Mercier E, Mira JP, Monseau Y, Parmentier-Decrucq E, Rigaud JP, Rouget A, Santoli F, Simon G, Tamion F, Thieulot-Rolin N, Thirion M, Valade S, Vinatier I, Vioulac C, Bailly S, Timsit JF
The ICU-Diary study: prospective, multicenter comparative study of the impact of an ICU diary on the wellbeing of patients and families in French ICUs.
Trials 2017, 18, 542.

Dupuis C, Sonneville R, Adrie C, Gros A, Darmon M, Bouadma L, Timsit JF
Impact of transfusion on patients with sepsis admitted in intensive care unit: a systematic review and meta-analysis.
Annals of Intensive Care 2017, 7, 5.

Adrie C, Lugosi M, Sonneville R, Souweine B, Ruckly S, Cartier JC, Garrouste-Orgeas M, Schwebel C, Timsit JF, Osg
Persistent lymphopenia is a risk factor for ICU-acquired infections and for death in ICU patients with sustained hypotension at admission.
Annals of Intensive Care 2017, 7, 30.

Neuville M, El-Helali N, Magalhaes E, Radjou A, Smonig R, Soubirou JF, Voiriot G, Le Monnier A, Ruckly S, Bouadma L, Sonneville R, Timsit JF, Mourvillier B
Systematic overdosing of oxa- and cloxacillin in severe infections treated in ICU: risk factors and side effects.
Annals of Intensive Care 2017, 7, 34.

Timsit JF, Esaied W, Neuville M, Bouadma L, Mourvllier B
Update on ventilator-associated pneumonia.
F1000Research 2017, 6, 2061.

Azoulay E, Timsit JF, Lautrette A, Legriel S, Max A, Ruckly S, Misset B, Cohen Y, Wolff M
Weekly high-dose liposomal amphotericin B (L-AmB) in critically ill septic patients with multiple Candida colonization: The AmBiDex study.
PloS One 2017, 12, e0177093.

Visseaux B, Burdet C, Voiriot G, Lescure FX, Chougar T, Brugiere O, Crestani B, Casalino E, Charpentier C, Descamps D, Timsit JF, Yazdanpanah Y, Houhou-Fidouh N
Prevalence of respiratory viruses among adults, by season, age, respiratory tract region and type of medical unit in Paris, France, from 2011 to 2016.
PLoS One 2017, 12, e0180888.

Ibn Saied W, Souweine B, Garrouste-Orgeas M, Ruckly S, Darmon M, Bailly S, Cohen Y, Azoulay E, Schwebel C, Radjou A, Kallel H, Adrie C, Dumenil AS, Argaud L, Marcotte G, Jamali S, Papazian L, Goldgran-Toledano D, Bouadma L, Timsit JF, Osg
Respective impact of implementation of prevention strategies, colonization with multiresistant bacteria and antimicrobial use on the risk of early- and late-onset VAP: An analysis of the OUTCOMEREA network.
PloS One 2017, 12, e0187791.

Neuville M, Mourvillier B, Bouadma L, Timsit JF
Bundle of care decreased ventilator-associated events-implications for ventilator-associated pneumonia prevention.
Journal of Thoracic Disease 2017, 9, 430-433.

Ara-Somohano C, Bonadona A, Carpentier F, Pavese P, Vesin A, Hamidfar-Roy R, Minet C, Vanzetto G, Schwebel C, Timsit JF
Evaluation of eight biomarkers to predict short-term mortality in patients with acute severe dyspnea.
Minerva Anestesiologica 2017, 83, 824-835.

Sommer H, Timsit JF, Wolkewitz M
Bezlotoxumab and Recurrent Clostridium difficile Infection.
The New England Journal of Medicine 2017, 376, 1594.

2016


Timsit JF, Azoulay E, Schwebel C, Charles PE, Cornet M, Souweine B, Klouche K, Jaber S, Trouillet JL, Bruneel F, Argaud L, Cousson J, Meziani F, Gruson D, Paris A, Darmon M, Garrouste-Orgeas M, Navellou JC, Foucrier A, Allaouchiche B, Das V, Gangneux JP, Ruckly S, Maubon D, Jullien V, Wolff M, ETG
Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure: The EMPIRICUS Randomized Clinical Trial.
JAMA 2016, 316, 1555-1564.

Bailly S, Pirracchio R, Timsit JF
What's new in the quantification of causal effects from longitudinal cohort studies: a brief introduction to marginal structural models for intensivists.
Intensive Care Medicine 2016, 42, 576-579.

Poulakou G, Bassetti M, Timsit JF
Critically ill migrants with infection: diagnostic considerations for intensive care physicians in Europe.
Intensive Care Medicine 2016, 42, 245-248.

Sakr Y, Ferrer R, Reinhart K, Beale R, Rhodes A, Moreno R, Timsit JF, Brochard L, Thompson BT, Rezende E, Chiche JD, IGI, ETG
The Intensive Care Global Study on Severe Acute Respiratory Infection (IC-GLOSSARI): a multicenter, multinational, 14-day inception cohort study.
Intensive Care Medicine 2016, 42, 817-828.

Mimoz O, Chopra V, Timsit JF
What's new in catheter-related infection: skin cleansing and skin antisepsis.
Intensive Care Medicine 2016, 42, 1784-1786.

Gélisse E, Neuville M, de Montmollin E, Bouadma L, Mourvillier B, Timsit JF, Sonneville R
Extracorporeal membrane oxygenation (ECMO) does not impact on amikacin pharmacokinetics: a case-control study.
Intensive Care Medicine 2016, 42, 946-948.

Bassetti M, Poulakou G, Timsit JF
Focus on antimicrobial use in the era of increasing antimicrobial resistance in ICU.
Intensive Care Medicine 2016, 42, 955-958.

Truche AS, Darmon M, Bailly S, Clec'h C, Dupuis C, Misset B, Azoulay E, Schwebel C, Bouadma L, Kallel H, Adrie C, Dumenil AS, Argaud L, Marcotte G, Jamali S, Zaoui P, Laurent V, Goldgran-Toledano D, Sonneville R, Souweine B, Timsit JF, OSG
Continuous renal replacement therapy versus intermittent hemodialysis in intensive care patients: impact on mortality and renal recovery.
Intensive Care Medicine 2016, 42, 1408-1417.

Weiss E, Zahar JR, Garrouste-Orgeas M, Ruckly S, Essaied W, Schwebel C, Timsit JF, OSG
De-escalation of pivotal beta-lactam in ventilator-associated pneumonia does not impact outcome and marginally affects MDR acquisition.
Intensive Care Medicine 2016, 42, 2098-2100.

Citerio G, Perner A, Timsit JF
The ten wishes and hopes of the deputy editors of Intensive Care Medicine.
Intensive Care Medicine 2016, 42, 1316-1318.

Timsit JF, Paiva JA, Bassetti M
Focus on optimization of early antimicrobial therapy in ICU-acquired infections.
Intensive Care Medicine 2016, 42, 1658-1660.

Truche AS, Darmon M, Timsit JF, OSG
Renal replacement therapy modalities in the ICU: the continuity is intermittent-response to comments by Schefold.
Intensive Care Medicine 2016, 42, 1840-1841.

Benoit DD, Doig G, Timsit JF
Focus on adequate antimicrobial treatment and de-escalation in the ICU.
Intensive Care Medicine 2016, 42, 1856-1858.

Günther SC, Schwebel C, Hamidfar-Roy R, Bonadona A, Lugosi M, Ara-Somohano C, Minet C, Potton L, Cartier JC, Vésin A, Chautemps M, Styfalova L, Ruckly S, Timsit JF
Complications of intravascular catheters in ICU: definitions, incidence and severity. A randomized controlled trial comparing usual transparent dressings versus new-generation dressings (the ADVANCED study).
Intensive Care Medicine 2016, 42, 1753-1765.

Timsit JF, Perner A
Sepsis: find me, manage me, and stop me!.
Intensive Care Medicine 2016, 42, 1851-1853.

Bailly S, Garnaud C, Cornet M, Pavese P, Hamidfar-Roy R, Foroni L, Boisset S, Timsit JF, Maubon D
Impact of systemic antifungal therapy on the detection of Candida species in blood cultures in clinical cases of candidemia.
European Journal of Clinical Microbiology & Infectious Diseases: Official Publication of the European Society of Clinical Microbiology 2016, 35, 1023-1032.

Bailly S, Maubon D, Fournier P, Pelloux H, Schwebel C, Chapuis C, Foroni L, Cornet M, Timsit JF
Impact of antifungal prescription on relative distribution and susceptibility of Candida spp. - Trends over 10 years.
The Journal of Infection 2016, 72, 103-111.

Pépin JL, Timsit JF, Tamisier R, Borel JC, Lévy P, Jaber S
Prevention and care of respiratory failure in obese patients.
The Lancet. Respiratory Medicine 2016, 4, 407-418.

Tabah A, Cotta MO, Garnacho-Montero J, Schouten J, Roberts JA, Lipman J, Tacey M, Timsit JF, Leone M, Zahar JR, De Waele JJ, WGfAUitI
A Systematic Review of the Definitions, Determinants, and Clinical Outcomes of Antimicrobial De-escalation in the Intensive Care Unit.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2016, 62, 1009-1017.

Barbier F, Pommier C, Essaied W, Garrouste-Orgeas M, Schwebel C, Ruckly S, Dumenil AS, Lemiale V, Mourvillier B, Clec'h C, Darmon M, Laurent V, Marcotte G, Lucet JC, Souweine B, Zahar JR, Timsit JF, OSG
Colonization and infection with extended-spectrum β-lactamase-producing Enterobacteriaceae in ICU patients: what impact on outcomes and carbapenem exposure?.
The Journal of Antimicrobial Chemotherapy 2016, 71, 1088-1097.

Bassetti M, Peghin M, Timsit JF
The current treatment landscape: candidiasis.
The Journal of Antimicrobial Chemotherapy 2016, 71, ii13-ii22.

Garrouste-Orgeas M, Max A, Lerin T, Grégoire C, Ruckly S, Kloeckner M, Brochon S, Pichot E, Simons C, El-Mhadri M, Bruel C, Philippart F, Fournier J, Tiercelet K, Timsit JF, Misset B
Impact of Proactive Nurse Participation in ICU Family Conferences: A Mixed-Method Study.
Critical Care Medicine 2016, 44, 1116-1128.

Toubiana J, Timsit S, Ferroni A, Grasseau M, Nassif X, Lortholary O, Zahar JR, Chalumeau M
Community-Onset Extended-Spectrum β-Lactamase-Producing Enterobacteriaceae Invasive Infections in Children in a University Hospital in France.
Medicine 2016, 95, e3163.

Sonneville R, Mariotte E, Neuville M, Minaud S, Magalhaes E, Ruckly S, Cantier M, Voiriot G, Radjou A, Smonig R, Soubirou JF, Mourvillier B, Bouadma L, Wolff M, Timsit JF
Early-onset status epilepticus in patients with acute encephalitis.
Medicine 2016, 95, e4092.

Mourvillier B, Radjou A, Timsit JF
Subclavian site should be preferred for central venous access.
Evidence-Based Nursing 2016, 19, 126.

Pépin JL, Tamisier R, Baguet JP, Lepaulle B, Arbib F, Arnol N, Timsit JF, Lévy P
Fixed-pressure CPAP versus auto-adjusting CPAP: comparison of efficacy on blood pressure in obstructive sleep apnoea, a randomised clinical trial.
Thorax 2016, 71, 726-733.

Sartelli M, Weber DG, Ruppé E, Bassetti M, Wright BJ, Ansaloni L, Catena F, Coccolini F, Abu-Zidan FM, Coimbra R, Moore EE, Moore FA, Maier RV, De Waele JJ, Kirkpatrick AW, Griffiths EA, Eckmann C, Brink AJ, Mazuski JE, May AK, Sawyer RG, Mertz D, Montravers P, Kumar A, Roberts JA, Vincent JL, Watkins RR, Lowman W, Spellberg B, Abbott IJ, Adesunkanmi AK, Al-Dahir S, Al-Hasan MN, Agresta F, Althani AA, Ansari S, Ansumana R, Augustin G, Bala M, Balogh ZJ, Baraket O, Bhangu A, Beltrán MA, Bernhard M, Biffl WL, Boermeester MA, Brecher SM, Cherry-Bukowiec JR, Buyne OR, Cainzos MA, Cairns KA, Camacho-Ortiz A, Chandy SJ, Che Jusoh A, Chichom-Mefire A, Colijn C, Corcione F, Cui Y, Curcio D, Delibegovic S, Demetrashvili Z, De Simone B, Dhingra S, Diaz JJ, Di Carlo I, Dillip A, Di Saverio S, Doyle MP, Dorj G, Dogjani A, Dupont H, Eachempati SR, Enani MA, Egiev VN, Elmangory MM, Ferrada P, Fitchett JR, Fraga GP, Guessennd N, Giamarellou H, Ghnnam W, Gkiokas G, Goldberg SR, Gomes CA, Gomi H, Guzmán-Blanco M, Haque M, Hansen S, Hecker A, Heizmann WR, Herzog T, Hodonou AM, Hong SK, Kafka-Ritsch R, Kaplan LJ, Kapoor G, Karamarkovic A, Kees MG, Kenig J, Kiguba R, Kim PK, Kluger Y, Khokha V, Koike K, Kok KYY, Kong V, Knox MC, Inaba K, Isik A, Iskandar K, Ivatury RR, Labbate M, Labricciosa FM, Laterre PF, Latifi R, Lee JG, Lee YR, Leone M, Leppaniemi A, Li Y, Liang SY, Loho T, Maegele M, Malama S, Marei HE, Martin-Loeches I, Marwah S, Massele A, McFarlane M, Melo RB, Negoi I, Nicolau DP, Nord CE, Ofori-Asenso R, Omari AH, Ordonez CA, Ouadii M, Pereira Júnior GA, Piazza D, Pupelis G, Rawson TM, Rems M, Rizoli S, Rocha C, Sakakhushev B, Sanchez-Garcia M, Sato N, Segovia Lohse HA, Sganga G, Siribumrungwong B, Shelat VG, Soreide K, Soto R, Talving P, Tilsed JV, Timsit JF, Trueba G, Trung NT, Ulrych J, van Goor H, Vereczkei A, Vohra RS, Wani I, Uhl W, Xiao Y, Yuan KC, Zachariah SK, Zahar JR, Zakrison TL, Corcione A, Melotti RM, Viscoli C, Viale P
Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).
World journal of emergency surgery: WJES 2016, 11,

Paiva JA, Pereira JM, Tabah A, Mikstacki A, de Carvalho FB, Koulenti D, Ruckly S, Çakar N, Misset B, Dimopoulos G, Antonelli M, Rello J, Ma X, Tamowicz B, Timsit JF
Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study.
Critical Care (London, England) 2016, 20,

May F, El-Helali N, Timsit JF, Misset B
Absence of obvious link between supra-therapeutic serum levels of β lactams and clinical toxicity in ICU patients with acute renal failure treated with intermittent hemodialysis.
Critical Care (London, England) 2016, 20, 220.

Coupez E, Timsit JF, Ruckly S, Schwebel C, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Darmon M, Boyer A, Azoulay E, Bouadma L, Lautrette A, Souweine B
Guidewire exchange vs new site placement for temporary dialysis catheter insertion in ICU patients: is there a greater risk of colonization or dysfunction?.
Critical Care (London, England) 2016, 20, 230.

Voiriot G, Visseaux B, Cohen J, Nguyen LB, Neuville M, Morbieu C, Burdet C, Radjou A, Lescure FX, Smonig R, Armand-Lefevre L, Mourvillier B, Yazdanpanah Y, Soubirou JF, Ruckly S, Houhou-Fidouh N, Timsit JF
Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia.
Crit Care 2016, 20, 375.

Leroy O, Bailly S, Gangneux JP, Mira JP, Devos P, Dupont H, Montravers P, Perrigault PF, Constantin JM, Guillemot D, Azoulay E, Lortholary O, Bensoussan C, Timsit JF, Asg
Systemic antifungal therapy for proven or suspected invasive candidiasis: the AmarCAND 2 study.
Annals of Intensive Care 2016, 6, 2.

Garrouste-Orgeas M, Ruckly S, Grégoire C, Dumesnil AS, Pommier C, Jamali S, Golgran-Toledano D, Schwebel C, Clec'h C, Soufir L, Fartoukh M, Marcotte G, Argaud L, Verdière B, Darmon M, Azoulay E, Timsit JF
Treatment intensity and outcome of nonagenarians selected for admission in ICUs: a multicenter study of the Outcomerea Research Group.
Annals of Intensive Care 2016, 6, 31.

Garrouste-Orgeas M, Vinatier I, Tabah A, Misset B, Timsit JF
Reappraisal of visiting policies and procedures of patient's family information in 188 French ICUs: a report of the Outcomerea Research Group.
Annals of Intensive Care 2016, 6, 82.

Bailly S, Destors M, Grillet Y, Richard P, Stach B, Vivodtzev I, Timsit JF, Lévy P, Tamisier R, Pépin JL, scaiotFnsar(
Obstructive Sleep Apnea: A Cluster Analysis at Time of Diagnosis.
PloS One 2016, 11, e0157318.

2015


Bakker J, Perner A, Timsit JF
Evaluation of 7.5 years of Surviving Sepsis Campaign Guidelines.
Intensive Care Medicine 2015, 41, 151-153.

Toffart AC, Dhalluin X, Girard N, Chouaid C, Audigier-Valette C, Duruisseaux M, Mennecier B, Parrot A, Fournel P, Moro-Sibilot D, Timsit JF
Patients with advanced lung cancer harboring oncogenic mutations should be admitted to intensive care units.
Intensive Care Medicine [Letter] 2015, 41, 164-165.

Garrouste-Orgeas M, Perrin M, Soufir L, Vesin A, Blot F, Maxime V, Beuret P, Troché G, Klouche K, Argaud L, Azoulay E, Timsit JF
The Iatroref study: medical errors are associated with symptoms of depression in ICU staff but not burnout or safety culture.
Intensive Care Medicine 2015, 41, 273-284.

Reignier J, Darmon M, Sonneville R, Borel AL, Garrouste-Orgeas M, Ruckly S, Souweine B, Dumenil AS, Haouache H, Adrie C, Argaud L, Soufir L, Marcotte G, Laurent V, Goldgran-Toledano D, Clec'h C, Schwebel C, Azoulay E, Timsit JF
Impact of early nutrition and feeding route on outcomes of mechanically ventilated patients with shock: a post hoc marginal structural model study.
Intensive Care Medicine 2015, 41, 875-886.

Timsit JF, Perner A, Bakker J, Bassetti M, Benoit D, Cecconi M, Curtis JR, Doig GS, Herridge M, Jaber S, Joannidis M, Papazian L, Peters MJ, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Citerio G, Azoulay E
Year in review in Intensive Care Medicine 2014: III. Severe infections, septic shock, healthcare-associated infections, highly resistant bacteria, invasive fungal infections, severe viral infections, Ebola virus disease and paediatrics.
Intensive Care Medicine [YEAR IN REVIEW 2014] 2015, 41, 575-588.

Bretonnière C, Leone M, Milési C, Allaouchiche B, Armand-Lefevre L, Baldesi O, Bouadma L, Decré D, Figueiredo S, Gauzit R, Guery B, Joram N, Jung B, Lasocki S, Lepape A, Lesage F, Pajot O, Philippart F, Souweine B, Tattevin P, Timsit JF, Vialet R, Zahar JR, Misset B, Bedos JP
Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
Intensive Care Medicine 2015, 41, 1181-1196.

Bassetti M, Leon C, Timsit JF
Are prophylactic antifungals in highly colonized patients safe and effective?.
Intensive Care Medicine 2015, 41, 1336-1339.

Lautrette A, Garrouste-Orgeas M, Bertrand PM, Goldgran-Toledano D, Jamali S, Laurent V, Argaud L, Schwebel C, Mourvillier B, Darmon M, Ruckly S, Dumenil AS, Lemiale V, Souweine B, Timsit JF, OSG
Respective impact of no escalation of treatment, withholding and withdrawal of life-sustaining treatment on ICU patients' prognosis: a multicenter study of the Outcomerea Research Group.
Intensive Care Medicine 2015, 41, 1763-1772.

Bailly S, Leroy O, Montravers P, Constantin JM, Dupont H, Guillemot D, Lortholary O, Mira JP, Perrigault PF, Gangneux JP, Azoulay E, Timsit JF
Antifungal de-escalation was not associated with adverse outcome in critically ill patients treated for invasive candidiasis: post hoc analyses of the AmarCAND2 study data.
Intensive Care Medicine 2015, 41, 1931-1940.

Garnacho-Montero J, Dimopoulos G, Poulakou G, Akova M, Cisneros JM, De Waele J, Petrosillo N, Seifert H, Timsit JF, Vila J, Zahar JR, Bassetti M, ESoICM
Task force on management and prevention of Acinetobacter baumannii infections in the ICU.
Intensive Care Medicine 2015, 41, 2057-2075.

Birgand G, Toupet G, Rukly S, Antoniotti G, Deschamps MN, Lepelletier D, Pornet C, Stern JB, Vandamme YM, van der Mee-Marquet N, Timsit JF, Lucet JC
Air contamination for predicting wound contamination in clean surgery: A large multicenter study.
American Journal of Infection Control 2015, 43, 516-521.

Le Dorze M, Gault N, Foucrier A, Ruppé E, Mourvillier B, Woerther PL, Birgand G, Montravers P, Dilly MP, Tubach F, Andremont A, Timsit JF, Wolff M, Armand-Lefèvre L
Performance and impact of a rapid method combining mass spectrometry and direct antimicrobial susceptibility testing on treatment adequacy of patients with ventilator-associated pneumonia.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015, 21, 468.e1-6.

Weiss E, Zahar JR, Lesprit P, Ruppe E, Leone M, Chastre J, Lucet JC, Paugam-Burtz C, Brun-Buisson C, Timsit JF, DeSG
Elaboration of a consensual definition of de-escalation allowing a ranking of β-lactams.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2015, 21, 649.e1-10.

Shadoud L, Almahmoud I, Jarraud S, Etienne J, Larrat S, Schwebel C, Timsit JF, Schneider D, Maurin M
Hidden Selection of Bacterial Resistance to Fluoroquinolones In Vivo: The Case of Legionella pneumophila and Humans.
EBioMedicine 2015, 2, 1179-1185.

Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S, Friggeri A, Wallet F, Allou N, Ruckly S, Balayn D, Lepape A, Timsit JF, Cti
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.
Lancet (London, England) 2015, 386, 2069-2077.

Molina JM, Capitant C, Spire B, Pialoux G, Cotte L, Charreau I, Tremblay C, Le Gall JM, Cua E, Pasquet A, Raffi F, Pintado C, Chidiac C, Chas J, Charbonneau P, Delaugerre C, Suzan-Monti M, Loze B, Fonsart J, Peytavin G, Cheret A, Timsit J, Girard G, Lorente N, Préau M, Rooney JF, Wainberg MA, Thompson D, Rozenbaum W, Doré V, Marchand L, Simon MC, Etien N, Aboulker JP, Meyer L, Delfraissy JF, AISG
On-Demand Preexposure Prophylaxis in Men at High Risk for HIV-1 Infection.
The New England Journal of Medicine 2015, 373, 2237–2246.

Tabah A, De Waele J, Lipman J, Zahar JR, Cotta MO, Barton G, Timsit JF, Roberts JA, WGfAUitIwtISotESoICM(
The ADMIN-ICU survey: a survey on antimicrobial dosing and monitoring in ICUs.
The Journal of Antimicrobial Chemotherapy 2015, 70, 2671-2677.

Bouadma L, Sonneville R, Garrouste-Orgeas M, Darmon M, Souweine B, Voiriot G, Kallel H, Schwebel C, Goldgran-Toledano D, Dumenil AS, Argaud L, Ruckly S, Jamali S, Planquette B, Adrie C, Lucet JC, Azoulay E, Timsit JF, OSG
Ventilator-Associated Events: Prevalence, Outcome, and Relationship With Ventilator-Associated Pneumonia.
Critical Care Medicine 2015, 43, 1798-1806.

Sonneville R, Gault N, de Montmollin E, Klein IF, Mariotte E, Chemam S, Tubach F, Mourvillier B, Timsit JF, Wolff M, Bouadma L
Clinical spectrum and outcomes of patients with encephalitis requiring intensive care.
European Journal of Neurology: The Official Journal of the European Federation of Neurological Societies 2015, 22, 6-16, e1.

Borel JC, Pelletier J, Taleux N, Briault A, Arnol N, Pison C, Tamisier R, Timsit JF, Pepin JL
Parameters recorded by software of non-invasive ventilators predict COPD exacerbation: a proof-of-concept study.
Thorax 2015, 70, 284-285.

Souweine B, Lautrette A, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Guelon D, Darmon M, Vesin A, Caillot N, Schwebel C, Boyer A, Azoulay E, Bouadma L, Timsit JF
Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2015, 191, 1024-1032.

Bailly S, Bouadma L, Azoulay E, Orgeas MG, Adrie C, Souweine B, Schwebel C, Maubon D, Hamidfar-Roy R, Darmon M, Wolff M, Cornet M, Timsit JF
Failure of empirical systemic antifungal therapy in mechanically ventilated critically ill patients.
American Journal of Respiratory and Critical Care Medicine 2015, 191, 1139-1146.

Toffart AC, Pizarro CA, Schwebel C, Sakhri L, Minet C, Duruisseaux M, Azoulay E, Moro-Sibilot D, Timsit JF
Selection criteria for intensive care unit referral of lung cancer patients: a pilot study.
European Respiratory Journal 2015, 45, 491-500.

Sartelli M, Malangoni MA, Abu-Zidan FM, Griffiths EA, Di Bella S, McFarland LV, Eltringham I, Shelat VG, Velmahos GC, Kelly CP, Khanna S, Abdelsattar ZM, Alrahmani L, Ansaloni L, Augustin G, Bala M, Barbut F, Ben-Ishay O, Bhangu A, Biffl WL, Brecher SM, Camacho-Ortiz A, Caínzos MA, Canterbury LA, Catena F, Chan S, Cherry-Bukowiec JR, Clanton J, Coccolini F, Cocuz ME, Coimbra R, Cook CH, Cui Y, Czepiel J, Das K, Demetrashvili Z, Di Carlo I, Di Saverio S, Dumitru IM, Eckert C, Eckmann C, Eiland EH, Enani MA, Faro M, Ferrada P, Forrester JD, Fraga GP, Frossard JL, Galeiras R, Ghnnam W, Gomes CA, Gorrepati V, Ahmed MH, Herzog T, Humphrey F, Kim JI, Isik A, Ivatury R, Lee YY, Juang P, Furuya-Kanamori L, Karamarkovic A, Kim PK, Kluger Y, Ko WC, LaBarbera FD, Lee JG, Leppaniemi A, Lohsiriwat V, Marwah S, Mazuski JE, Metan G, Moore EE, Moore FA, Nord CE, Ordoñez CA, Júnior GAP, Petrosillo N, Portela F, Puri BK, Ray A, Raza M, Rems M, Sakakushev BE, Sganga G, Spigaglia P, Stewart DB, Tattevin P, Timsit JF, To KB, Tranà C, Uhl W, Urbánek L, van Goor H, Vassallo A, Zahar JR, Caproli E, Viale P
WSES guidelines for management of Clostridium difficile infection in surgical patients.
World journal of emergency surgery: WJES 2015, 10,

Minet C, Potton L, Bonadona A, Hamidfar-Roy R, Somohano CA, Lugosi M, Cartier JC, Ferretti G, Schwebel C, Timsit JF
Venous thromboembolism in the ICU: main characteristics, diagnosis and thromboprophylaxis.
Critical Care (London, England) 2015, 19,

Timsit JF, Chemam S, Bailly S
Empiric/pre-emptive anti-Candida therapy in non-neutropenic ICU patients.
F1000prime Reports 2015, 7, 21.

Venot M, Weis L, Clec'h C, Darmon M, Allaouchiche B, Goldgran-Tolédano D, Garrouste-Orgeas M, Adrie C, Timsit JF, Azoulay E
Acute Kidney Injury in Severe Sepsis and Septic Shock in Patients with and without Diabetes Mellitus: A Multicenter Study.
PloS One 2015, 10, e0127411.

Maunoury F, Motrunich A, Palka-Santini M, Bernatchez SF, Ruckly S, Timsit JF
Cost-Effectiveness Analysis of a Transparent Antimicrobial Dressing for Managing Central Venous and Arterial Catheters in Intensive Care Units.
PloS One 2015, 10, e0130439.

Philippart F, Bouroche G, Timsit JF, Garrouste-Orgeas M, Azoulay E, Darmon M, Adrie C, Allaouchiche B, Ara-Somohano C, Ruckly S, Dumenil AS, Souweine B, Goldgran-Toledano D, Bouadma L, Misset B, Osg
Decreased Risk of Ventilator-Associated Pneumonia in Sepsis Due to Intra-Abdominal Infection.
PloS One 2015, 10, e0137262.

Maignan M, Richard A, Debaty G, Pommier P, Viglino D, Loizzo F, Timsit JF, Hanna J, Carpentier F, Danel V
Intentional Drug Poisoning Care in a Physician-manned Emergency Medical Service.
Prehospital emergency care: official journal of the National Association of EMS Physicians and the National Association of State EMS Directors 2015, 19, 224-231.

Dimopoulos G, Koulenti D, Tabah A, Poulakou G, Vesin A, Arvaniti K, Lathyris D, Matthaiou DK, Armaganidis A, Timsit JF
Bloodstream infections in ICU with increased resistance: epidemiology and outcomes.
Minerva Anestesiologica 2015, 81, 405-418.

2014


van Zanten ARH, Sztark F, Kaisers UX, Zielmann S, Felbinger TW, Sablotzki AR, De Waele JJ, Timsit JF, Honing MLH, Keh D, Vincent JL, Zazzo JF, Fijn HBM, Petit L, Preiser JC, van Horssen PJ, Hofman Z
High-protein enteral nutrition enriched with immune-modulating nutrients vs standard high-protein enteral nutrition and nosocomial infections in the ICU: a randomized clinical trial.
JAMA: the journal of the American Medical Association 2014, 312, 514-524.

Citerio G, Bakker J, Bassetti M, Benoit D, Cecconi M, Curtis JR, Hernandez G, Herridge M, Jaber S, Joannidis M, Papazian L, Peters M, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Timsit JF, Azoulay E
Year in review in Intensive Care Medicine 2013: I. Acute kidney injury, ultrasound, hemodynamics, cardiac arrest, transfusion, neurocritical care, and nutrition.
Intensive Care Medicine 2014, 40, 147-159.

Azoulay E, Citerio G, Bakker J, Bassetti M, Benoit D, Cecconi M, Curtis JR, Hernandez G, Herridge M, Jaber S, Joannidis M, Papazian L, Peters M, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Timsit JF
Year in review in Intensive Care Medicine 2013: II. Sedation, invasive and noninvasive ventilation, airways, ARDS, ECMO, family satisfaction, end-of-life care, organ donation, informed consent, safety, hematological issues in critically ill patients.
Intensive care medicine [YEAR IN REVIEW 2013] 2014, 40, 305-319.

Schnell D, Timsit JF, Darmon M, Vesin A, Goldgran-Toledano D, Dumenil AS, Garrouste-Orgeas M, Adrie C, Bouadma L, Planquette B, Cohen Y, Schwebel C, Soufir L, Jamali S, Souweine B, Azoulay E
Noninvasive mechanical ventilation in acute respiratory failure: trends in use and outcomes.
Intensive Care Medicine 2014, 40, 582-591.

Timsit JF, Citerio G, Bakker J, Bassetti M, Benoit D, Cecconi M, Curtis JR, Hernandez G, Herridge M, Jaber S, Joannidis M, Papazian L, Peters M, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Azoulay E
Year in review in Intensive Care Medicine 2013: III. Sepsis, infections, respiratory diseases, pediatrics.
Intensive care medicine [YEAR IN REVIEW 2013] 2014, 40, 471-483.

Timsit JF, Harbarth S, Carlet J
De-escalation as a potential way of reducing antibiotic use and antimicrobial resistance in ICU.
Intensive Care Medicine 2014, 40, 1580-1582.

Wolff M, Mourvillier B, Sonneville R, Timsit JF
My paper 10 years later: infective endocarditis in the intensive care unit.
Intensive Care Medicine [MY PAPER 20 YEARS LATER] 2014, 40, 1843-1852.

Debaty G, Maignan M, Savary D, Koch FX, Ruckly S, Durand M, Picard J, Escallier C, Chouquer R, Santre C, Minet C, Guergour D, Hammer L, Bouvaist H, Belle L, Adrie C, Payen JF, Carpentier F, Gueugniaud PY, Danel V, Timsit JF
Impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial.
Intensive Care Medicine 2014, 40, 1832-1842.

Elsen S, Huber P, Bouillot S, Couté Y, Fournier P, Dubois Y, Timsit JF, Maurin M, Attrée I
A type III secretion negative clinical strain of Pseudomonas aeruginosa employs a two-partner secreted exolysin to induce hemorrhagic pneumonia.
Cell Host & Microbe 2014, 15, 164-176.

Elliott T, Timsit JF
epic3: guidelines for preventing infections associated with the use of intravascular access devices.
The Journal of Hospital Infection 2014, 87, 182.

Lugosi M, Alberti C, Zahar JR, Garrouste M, Lemiale V, Descorps-Desclère A, Ricard JD, Goldgran-Tolédano D, Cohen Y, Schwebel C, Vésin A, Timsit JF, Azoulay E
Aspergillus in the lower respiratory tract of immunocompetent critically ill patients.
The Journal of Infection 2014, 69, 284-292.

Zahar JR, Lucet JC, Timsit JF
Antimicrobial resistance in intensive care units.
The Lancet. Infectious Diseases 2014, 14, 3-5.

Soares M, Toffart AC, Timsit JF, Burghi G, Irrazábal C, Pattison N, Tobar E, Almeida BFC, Silva UVA, Azevedo LCP, Rabbat A, Lamer C, Parrot A, Souza-Dantas VC, Wallet F, Blot F, Bourdin G, Piras C, Delemazure J, Durand M, Tejera D, Salluh JIF, Azoulay E, LCiCC(SI
Intensive care in patients with lung cancer: a multinational study.
Annals of Oncology: Official Journal of the European Society for Medical Oncology 2014, 25, 1829-1835.

Mirabel M, Sonneville R, Hajage D, Novy E, Tubach F, Vignon P, Perez P, Lavoue S, Kouatchet A, Pajot O, Mekontso-Dessap A, Tonnelier JM, Bollaert PE, Frat JP, Navellou JC, Hyvernat H, Hssain AA, Timsit JF, Megarbane B, Wolff M, Trouillet JL, ftESG
Long-term outcomes and cardiac surgery in critically ill patients with infective endocarditis.
European Heart Journal 2014, 35, 1195-1204.

Chumpitazi BFF, Lebeau B, Faure-Cognet O, Hamidfar-Roy R, Timsit JF, Pavese P, Thiebaut-Bertrand A, Quesada JL, Pelloux H, Pinel C
Characteristic and clinical relevance of Candida mannan test in the diagnosis of probable invasive candidiasis.
Medical Mycology 2014, 52, 462-471.

Garrouste-Orgeas M, Ben-Rehouma M, Darmon M, Ruckly S, Clec'h C, Adrie C, Tabah A, Vesin A, Schwebel C, Misset B, Timsit JF
ICU physician-based determinants of life-sustaining therapy during nights and weekends: French multicenter study from the Outcomerea Research Group.
Critical Care Medicine 2014, 42, 2393-2400.

Darmon M, Pichon M, Schwebel C, Ruckly S, Adrie C, Haouache H, Azoulay E, Bouadma L, Clec'h C, Garrouste-Orgeas M, Souweine B, Goldgran-Toledano D, Khallel H, Argaud L, Dumenil AS, Jamali S, Allaouchiche B, Zeni F, Timsit JF
Influence of early dysnatremia correction on survival of critically ill patients.
Shock (Augusta, Ga.) 2014, 41, 394-399.

Gagneux-Brunon A, Timsit JF, Lepape A, Berthelot P
Vascular catheter-related infection claims to health insurance company: often preventable.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2014, 20, O1084-1087.

Borel JC, Pepin JL, Pison C, Vesin A, Gonzalez-Bermejo J, Court-Fortune I, Timsit JF
Long-term adherence with non-invasive ventilation improves prognosis in obese COPD patients.
Respirology (Carlton, Vic.) 2014, 19, 857-865.

Pépin JL, Timsit JF, Tamisier R, Lévy P
Is CPAP effective in reducing blood pressure in minimally symptomatic obstructive sleep apnoea?.
Thorax [Editorial] 2014, 69, 1068-1070.

Borel JC, Pison C, Timsit JF, Pepin JL
Domiciliary long-term non-invasive ventilation in COPD: should we select subgroups with a better likelihood to respond to NIV in subsequent randomised controlled trials?.
Thorax 2014, 69, 1143.

Puntillo KA, Max A, Timsit JF, Vignoud L, Chanques G, Robleda G, Roche-Campo F, Mancebo J, Divatia JV, Soares M, Ionescu DC, Grintescu I, Vasiliu IL, Maggiore SM, Rusinova K, Owczuk R, Egerod I, Papathanassoglou EDE, Kyranou M, Joynt GM, Burghi G, Freebairn RC, Ho KM, Kaarlola A, Gerritsen RT, Kesecioglu J, Sulaj MMS, Norrenberg M, Benoit DD, Seha MSG, Hennein A, Periera FJ, Benbenishty JS, Abroug F, Aquilina A, Monte JRC, An Y, Azoulay E
Determinants of Procedural Pain Intensity in the Intensive Care Unit The Europain (R) Study.
American Journal of Respiratory and Critical Care Medicine 2014, 189, 39-47.

Weiss E, Timsit JF
Management of invasive candidiasis in nonneutropenic ICU patients.
Therapeutic Advances in Infectious Disease 2014, 2, 105-115.

Timsit JF, Soubirou JF, Voiriot G, Chemam S, Neuville M, Mourvillier B, Sonneville R, Mariotte E, Bouadma L, Wolff M
Treatment of bloodstream infections in ICUs.
BMC infectious diseases 2014, 14, 489.

Toffart AC, Moro-Sibilot D, Couraud S, Merle P, Perol M, Girard N, Souquet PJ, Mastroianni B, Ferretti GR, Romand P, Chatellain P, Vesin A, Brambilla E, Brambilla C, Timsit JF
Evaluation of RECIST in chemotherapy-treated lung cancer: the Pharmacogenoscan Study.
Bmc Cancer 2014, 14, 989.

Tolsma V, Schwebel C, Azoulay E, Darmon M, Souweine B, Vesin A, Goldgran-Toledano D, Lugosi M, Jamali S, Cheval C, Adrie C, Kallel H, Descorps-Declere A, Garrouste-Orgeas M, Bouadma L, Timsit JF
Sepsis severe or septic shock: outcome according to immune status and immunodeficiency profile.
Chest 2014, 146, 1205-1213.

Darmon M, Clec'h C, Adrie C, Argaud L, Allaouchiche B, Azoulay E, Bouadma L, Garrouste-Orgeas M, Haouache H, Schwebel C, Goldgran-Toledano D, Khallel H, Dumenil AS, Jamali S, Souweine B, Zeni F, Cohen Y, Timsit JF
Acute respiratory distress syndrome and risk of AKI among critically ill patients.
Clinical journal of the American Society of Nephrology: CJASN 2014, 9, 1347-1353.

Borel AL, Schwebel C, Planquette B, Vésin A, Garrouste-Orgeas M, Adrie C, Clec'h C, Azoulay E, Souweine B, Allaouchiche B, Goldgran-Toledano D, Jamali S, Darmon M, Timsit JF
Initiation of nutritional support is delayed in critically ill obese patients: a multicenter cohort study.
The American Journal of Clinical Nutrition 2014, 100, 859-866.

2013


Demaret J, Walencik A, Jacob MC, Timsit JF, Venet F, Lepape A, Monneret G
Inter-laboratory assessment of flow cytometric monocyte HLA-DR expression in clinical samples.
Cytometry. Part B, Clinical Cytometry 2013, 84, 59-62.

Antonelli M, Bonten M, Cecconi M, Chastre J, Citerio G, Conti G, Curtis JR, Hedenstierna G, Joannidis M, Macrae D, Maggiore SM, Mancebo J, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H
Year in review in Intensive Care Medicine 2012: I. Neurology and neurointensive care, epidemiology and nephrology, biomarkers and inflammation, nutrition, experimentals.
Intensive Care Medicine 2013, 39, 232-246.

Antonelli M, Bonten M, Cecconi M, Chastre J, Citerio G, Conti G, Curtis JR, Hedenstierna G, Joannidis M, Macrae D, Maggiore SM, Mancebo J, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H
Year in review in Intensive Care Medicine 2012. II: Pneumonia and infection, sepsis, coagulation, hemodynamics, cardiovascular and microcirculation, critical care organization, imaging, ethics and legal issues.
Intensive Care Medicine 2013, 39, 345-364.

Antonelli M, Bonten M, Cecconi M, Chastre J, Citerio G, Conti G, Curtis JR, Hedenstierna G, Joannidis M, Macrae D, Maggiore SM, Mancebo J, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H
Year in review in Intensive Care Medicine 2012: III. Noninvasive ventilation, monitoring and patient-ventilator interactions, acute respiratory distress syndrome, sedation, paediatrics and miscellanea.
Intensive Care Medicine 2013, 39, 543-557.

Potton L, Bonadona A, Minet C, Timsit JF
Pink urine.
Intensive Care Medicine 2013, 39, 389-390.

Vesin A, Azoulay E, Ruckly S, Vignoud L, Rusinovà K, Benoit D, Soares M, Azeivedo-Maia P, Abroug F, Benbenishty J, Timsit JF
Reporting and handling missing values in clinical studies in intensive care units.
Intensive Care Medicine 2013, 39, 1396-1404.

Thiolliere F, Serre-Sapin AF, Reignier J, Benedit M, Constantin JM, Lebert C, Guélon D, Timsit JF, Souweine B
Epidemiology and outcome of thrombocytopenic patients in the intensive care unit: results of a prospective multicenter study.
Intensive Care Medicine 2013, 39, 1460-1468.

Philippart F, Vesin A, Bruel C, Kpodji A, Durand-Gasselin B, Garçon P, Levy-Soussan M, Jagot JL, Calvo-Verjat N, Timsit JF, Misset B, Garrouste-Orgeas M
The ETHICA study (part I): elderly's thoughts about intensive care unit admission for life-sustaining treatments.
Intensive Care Medicine 2013, 39, 1565-1573.

Garrouste-Orgeas M, Tabah A, Vesin A, Philippart F, Kpodji A, Bruel C, Grégoire C, Max A, Timsit JF, Misset B
The ETHICA study (part II): simulation study of determinants and variability of ICU physician decisions in patients aged 80 or over.
Intensive Care Medicine 2013, 39, 1574-1583.

Zahar JR, Garrouste-Orgeas M, Vesin A, Schwebel C, Bonadona A, Philippart F, Ara-Somohano C, Misset B, Timsit JF
Impact of contact isolation for multidrug-resistant organisms on the occurrence of medical errors and adverse events.
Intensive Care Medicine 2013, 39, 2153-2160.

Fagedet D, Thony F, Timsit JF, Rodiere M, Monnin-Bares V, Ferretti GR, Vesin A, Moro-Sibilot D
Endovascular treatment of malignant superior vena cava syndrome: results and predictive factors of clinical efficacy.
Cardiovascular and Interventional Radiology 2013, 36, 140-149.

Stahl JP, Salmon D, Bruneel F, Caumes E, Freymuth F, Bru JP, Morand P, Roblot F, Schmit JL, Strady C, Timsit JF, Rabaud C, I
Adult patients hospitalized for measles in France, in the 21st century.
Medecine Et Maladies Infectieuses 2013, 43, 410-416.

Timsit JF, Laupland KB
Is the burden of severe sepsis and septic shock changing?.
Critical Care Medicine 2013, 41, 1361-1363.

Schwebel C, Clec'h C, Magne S, Minet C, Garrouste-Orgeas M, Bonadona A, Dumenil AS, Jamali S, Kallel H, Goldgran-Toledano D, Marcotte G, Azoulay E, Darmon M, Ruckly S, Souweine B, Timsit JF
Safety of Intrahospital Transport in Ventilated Critically Ill Patients: A Multicenter Cohort Study.
Critical Care Medicine 2013, 41, 1919-1928.

Murat JB, Lebeau B, Chumpitazi B, Cornet M, Maubon D, Faure O, Quesada JL, Thiebaut-Bertrand A, Timsit JF, Pelloux H
Minimum inhibitory concentrations of amphotericin B against Candida krusei isolates from a French teaching hospital laboratory: a retrospective study over 8 years.
Mycoses 2013, 56, 56-60.

Rousseaux S, Debernardi A, Jacquiau B, Vitte AL, Vesin A, Nagy-Mignotte H, Moro-Sibilot D, Brichon PY, Lantuejoul S, Hainaut P, Laffaire J, de Reyniès A, Beer DG, Timsit JF, Brambilla C, Brambilla E, Khochbin S
Ectopic activation of germline and placental genes identifies aggressive metastasis-prone lung cancers.
Science Translational Medicine 2013, 5, 186ra66.

Planquette B, Timsit JF, Misset BY, Schwebel C, Azoulay E, Adrie C, Vesin A, Jamali S, Zahar JR, Allaouchiche B, Souweine B, Darmon M, Dumenil AS, Goldgran-Toledano D, Mourvillier BH, Bédos JP, OSG
Pseudomonas aeruginosa ventilator-associated pneumonia. predictive factors of treatment failure.
American Journal of Respiratory and Critical Care Medicine 2013, 188, 69-76.

Annane D, Timsit JF, Megarbane B, Martin C, Misset B, Mourvillier B, Siami S, Chagnon JL, Constantin JM, Petitpas F, Souweine B, Amathieu R, Forceville X, Charpentier C, Tesnière A, Chastre J, Bohe J, Colin G, Cariou A, Renault A, Brun-Buisson C, Bellissant E, ATI
Recombinant human activated protein C for adults with septic shock: a randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2013, 187, 1091-1097.

Timsit JF, Bouadma L, Mimoz O, Parienti JJ, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Herrault MC, Schwebel C, Ruckly S, Souweine B, Lucet JC
Jugular versus femoral short-term catheterization and risk of infection in intensive care unit patients. Causal analysis of two randomized trials.
American Journal of Respiratory and Critical Care Medicine 2013, 188, 1232-1239.

Goudet V, Timsit JF, Lucet JC, Lepape A, Balayn D, Seguin S, Mimoz O
Comparison of four skin preparation strategies to prevent catheter-related infection in intensive care unit (CLEAN trial): a study protocol for a randomized controlled trial.
Trials 2013, 14, 114.

Timsit JF, Azoulay E, Cornet M, Gangneux JP, Jullien V, Vésin A, Schir E, Wolff M
EMPIRICUS micafungin versus placebo during nosocomial sepsis in Candida multi-colonized ICU patients with multiple organ failures: study protocol for a randomized controlled trial.
Trials 2013, 14, 399.

Darmon M, Diconne E, Souweine B, Ruckly S, Adrie C, Azoulay E, Clec'h C, Garrouste-Orgeas M, Schwebel C, Goldgran-Toledano D, Khallel H, Dumenil AS, Jamali S, Cheval C, Allaouchiche B, Zeni F, Timsit JF
Prognostic consequences of borderline dysnatremia: pay attention to minimal serum sodium change.
Critical Care (London, England) 2013, 17, R12.

Toffart AC, Timsit JF
Is prolonged mechanical ventilation of cancer patients futile?.
Critical Care (London, England) 2013, 17, 189.

Adrie C, Schwebel C, Garrouste-Orgeas M, Vignoud L, Planquette B, Azoulay E, Kallel H, Darmon M, Souweine B, Dinh-Xuan AT, Jamali S, Zahar JR, Timsit JF, AWWobotOSG
Initial use of one or two antibiotics for critically ill patients with community-acquired pneumonia: impact on survival and bacterial resistance.
Critical Care (London, England) 2013, 17, R265.

Niven DJ, Laupland KB, Tabah A, Vesin A, Rello J, Koulenti D, Dimopoulos G, de Waele J, Timsit JF, EI
Diagnosis and management of temperature abnormality in ICUs: a EUROBACT investigators' survey.
Critical Care (London, England) 2013, 17, R289.

Zahar JR, Timsit JF
Clostridium difficile outcomes difficult to generalize. Authors' response.
Critical Care (London, England) 2013, 17, 415.

2012


Coeurjolly JF, Nguile-Makao M, Timsit JF, Liquet B
Attributable risk estimation for adjusted disability multistate models: application to nosocomial infections.
Biometrical Journal. Biometrische Zeitschrift 2012, 54, 600-616.

Antonelli M, Bonten M, Chastre J, Citerio G, Conti G, Curtis JR, De Backer D, Hedenstierna G, Joannidis M, Macrae D, Mancebo J, Maggiore SM, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H
Year in review in Intensive Care Medicine 2011: I. Nephrology, epidemiology, nutrition and therapeutics, neurology, ethical and legal issues, experimentals.
Intensive Care Medicine 2012, 38, 192-209.

Rhodes A, Moreno RP, Azoulay E, Capuzzo M, Chiche JD, Eddleston J, Endacott R, Ferdinande P, Flaatten H, Guidet B, Kuhlen R, León-Gil C, Martin Delgado MC, Metnitz PG, Soares M, Sprung CL, Timsit JF, Valentin A, TFoSaQoESoICM(
Prospectively defined indicators to improve the safety and quality of care for critically ill patients: a report from the Task Force on Safety and Quality of the European Society of Intensive Care Medicine (ESICM).
Intensive Care Medicine 2012, 38, 598-605.

Antonelli M, Bonten M, Chastre J, Citerio G, Conti G, Curtis JR, De Backer D, Hedenstierna G, Joannidis M, Macrae D, Mancebo J, Maggiore SM, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H
Year in review in Intensive Care Medicine 2011. II. Cardiovascular, infections, pneumonia and sepsis, critical care organization and outcome, education, ultrasonography, metabolism and coagulation.
Intensive Care Medicine 2012, 38, 345-358.

Antonelli M, Bonten M, Chastre J, Citerio G, Conti G, Curtis JR, De Backer D, Hedenstierna G, Joannidis M, Macrae D, Mancebo J, Maggiore SM, Mebazaa A, Preiser JC, Rocco P, Timsit JF, Wernerman J, Zhang H
Year in review in Intensive Care Medicine 2011: III. ARDS and ECMO, weaning, mechanical ventilation, noninvasive ventilation, pediatrics and miscellanea.
Intensive Care Medicine 2012, 38, 542-556.

Azoulay E, Garrouste M, Goldgran-Toledano D, Adrie C, Max A, Vesin A, Francais A, Zahar JR, Cohen Y, Allaouchiche B, Schlemmer B, Timsit JF
Increased nonbeneficial care in patients spending their birthday in the ICU.
Intensive Care Medicine 2012, 38, 1169-1176.

Timsit JF, L'Hériteau F, Lepape A, Francais A, Ruckly S, Venier AG, Jarno P, Boussat S, Coignard B, Savey A
A multicentre analysis of catheter-related infection based on a hierarchical model.
Intensive Care Medicine 2012, 38, 1662-1672.

Tabah A, Koulenti D, Laupland K, Misset B, Valles J, Bruzzi de Carvalho F, Paiva JA, Cakar N, Ma X, Eggimann P, Antonelli M, Bonten MJM, Csomos A, Krueger WA, Mikstacki A, Lipman J, Depuydt P, Vesin A, Garrouste-Orgeas M, Zahar JR, Blot S, Carlet J, Brun-Buisson C, Martin C, Rello J, Dimopoulos G, Timsit JF
Characteristics and determinants of outcome of hospital-acquired bloodstream infections in intensive care units: the EUROBACT International Cohort Study.
Intensive Care Medicine 2012, 38, 1930-1945.

Guillet M, Zahar JR, Timsit MO, Grandin L, Carbonnelle E, Join-Lambert O, Quesne G, Nassif X, Mejean A, Carbonne A
Horizontal transmission of Streptococcus pneumoniae in the surgical ward: a rare source of nosocomial wound infection.
American Journal of Infection Control 2012, 40, 71-72.

Ouanes I, Schwebel C, Français A, Bruel C, Philippart F, Vesin A, Soufir L, Adrie C, Garrouste-Orgeas M, Timsit JF, Misset B, OSG
A model to predict short-term death or readmission after intensive care unit discharge.
Journal of Critical Care 2012, 27, 422.e1-9.

Gibert P, Brudieu E, Timsit JF, Foroni L, Thiébaut-Bertrand A, Allenet B, Pelloux H, Brenier Pinchart MP
Invasive aspergillosis: drug-dispensing systems as a source of filamentous fungal contamination in high-risk units?.
The Journal of Hospital Infection 2012, 82, 293-296.

Nagy-Mignotte H, Guillem P, Vignoud L, Coudurier M, Vesin A, Bonneterre V, Toffart AC, Sakhri L, Brambilla C, Brambilla E, Timsit JF, Moro-Sibilot D, MTOG
Outcomes in recurrent small-cell lung cancer after one to four chemotherapy lines: a retrospective study of 300 patients.
Lung Cancer (Amsterdam, Netherlands) 2012, 78, 112-120.

Minet C, Vivodtzev I, Tamisier R, Arbib F, Wuyam B, Timsit JF, Monneret D, Borel JC, Baguet JP, Lévy P, Pépin JL
Reduced six-minute walking distance, high fat-free-mass index and hypercapnia are associated with endothelial dysfunction in COPD.
Respiratory Physiology & Neurobiology 2012, 183, 128-134.

Laupland KB, Zahar JR, Adrie C, Minet C, Vésin A, Goldgran-Toledano D, Azoulay E, Garrouste-Orgeas M, Cohen Y, Schwebel C, Jamali S, Darmon M, Dumenil AS, Kallel H, Souweine B, Timsit JF
Severe hypothermia increases the risk for intensive care unit-acquired infection.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012, 54, 1064-1070.

Schwebel C, Lucet JC, Vesin A, Arrault X, Calvino-Gunther S, Bouadma L, Timsit JF
Economic evaluation of chlorhexidine-impregnated sponges for preventing catheter-related infections in critically ill adults in the Dressing Study.
Critical Care Medicine 2012, 40, 11-17.

Laupland KB, Zahar JR, Adrie C, Schwebel C, Goldgran-Toledano D, Azoulay E, Garrouste-Orgeas M, Cohen Y, Jamali S, Souweine B, Darmon M, Timsit JF
Determinants of temperature abnormalities and influence on outcome of critical illness.
Critical Care Medicine 2012, 40, 145-151.

Garrouste-Orgeas M, Soufir L, Tabah A, Schwebel C, Vesin A, Adrie C, Thuong M, Timsit JF, OSG
A multifaceted program for improving quality of care in intensive care units: IATROREF study.
Critical Care Medicine 2012, 40, 468-476.

Azoulay E, Dupont H, Tabah A, Lortholary O, Stahl JP, Francais A, Martin C, Guidet B, Timsit JF
Systemic antifungal therapy in critically ill patients without invasive fungal infection*.
Critical Care Medicine 2012, 40, 813-822.

Parienti JJ, du Cheyron D, Timsit JF, Traoré O, Kalfon P, Mimoz O, Mermel LA
Meta-analysis of subclavian insertion and nontunneled central venous catheter-associated infection risk reduction in critically ill adults.
Critical Care Medicine 2012, 40, 1627-1634.

Timsit JF, Bouadma L, Ruckly S, Schwebel C, Garrouste-Orgeas M, Bronchard R, Calvino-Gunther S, Laupland K, Adrie C, Thuong M, Herault MC, Pease S, Arrault X, Lucet JC
Dressing disruption is a major risk factor for catheter-related infections.
Crit Care Med 2012, 40, 1707-14.

Garrouste-Orgeas M, Coquet I, Périer A, Timsit JF, Pochard F, Lancrin F, Philippart F, Vesin A, Bruel C, Blel Y, Angeli S, Cousin N, Carlet J, Misset B
Impact of an intensive care unit diary on psychological distress in patients and relatives*.
Critical Care Medicine 2012, 40, 2033-2040.

Minet C, Lugosi M, Savoye PY, Menez C, Ruckly S, Bonadona A, Schwebel C, Hamidfar-Roy R, Dumanoir P, Ara-Somohano C, Ferretti GR, Timsit JF
Pulmonary embolism in mechanically ventilated patients requiring computed tomography: Prevalence, risk factors, and outcome.
Critical Care Medicine 2012, 40, 3202-3208.

Timsit JF, Laupland KB
Update on bloodstream infections in ICUs.
Current Opinion in Critical Care 2012, 18, 479-486.

Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Lepape A, Vesin A, Arrault X, Schwebel C, Adrie C, Zahar JR, Ruckly S, Tournegros C, Lucet JC
Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults.
American Journal of Respiratory and Critical Care Medicine 2012, 186, 1272-1278.

Scoccianti C, Vesin A, Martel G, Olivier M, Brambilla E, Timsit JF, Tavecchio L, Brambilla C, Field JK, Hainaut P, EELCC
Prognostic value of TP53, KRAS and EGFR mutations in nonsmall cell lung cancer: the EUELC cohort.
The European Respiratory Journal 2012, 40, 177-184.

Liquet B, Timsit JF, Rondeau V
Investigating hospital heterogeneity with a multi-state frailty model: application to nosocomial pneumonia disease in intensive care units.
BMC medical research methodology 2012, 12, 79.

Mrozek N, Lautrette A, Timsit JF, Souweine B
How to deal with dialysis catheters in the ICU setting.
Annals of Intensive Care 2012, 2, 48.

Zahar JR, Schwebel C, Adrie C, Garrouste-Orgeas M, Français A, Vesin A, Nguile-Makao M, Tabah A, Laupland K, Le-Monnier A, Timsit JF, Osg
Outcome of ICU patients with Clostridium difficile infection.
Critical Care (London, England) 2012, 16, R215.

Clec'h C, Darmon M, Lautrette A, Chemouni F, Azoulay E, Schwebel C, Dumenil AS, Garrouste-Orgeas M, Goldgran-Toledano D, Cohen Y, Timsit JF
Efficacy of renal replacement therapy in critically ill patients: a propensity analysis.
Critical Care (London, England) 2012, 16, R236.

Pajares MJ, Agorreta J, Larrayoz M, Vesin A, Ezponda T, Zudaire I, Torre W, Lozano MD, Brambilla E, Brambilla C, Wistuba II, Behrens C, Timsit JF, Pio R, Field JK, Montuenga LM
Expression of tumor-derived vascular endothelial growth factor and its receptors is associated with outcome in early squamous cell carcinoma of the lung.
Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology 2012, 30, 1129-1136.

Lupo J, Bernard S, Wintenberger C, Baccard M, Vabret A, Antona D, Timsit JF, Morand P
Fatal measles without rash in immunocompetent adult, France.
Emerging Infectious Diseases 2012, 18, 521-523.

Research domains : Sepsis and antibiotic therapy, Catheter-related infections, Ventilator-associated pneumonia, fungal infections, multidrug resistant infections in ICU;Medication errors and Adverse Events, Improvement of quality of care in intensive care, High quality Database, Prognostic models, mortality, competing risks Supervision of masters and doctoral thesis : 16 Masters and 5 thesis in the past 7 years in clinical epidemiology.