Members

  First name: Lila
  Last name: Bouadma
  Function: Professor of Intensive Care Medicine
  Position: Professor of Intensice Care Medicine, Université Paris Cité
  Email: lila.bouadma
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aphp.fr

Research interest



Exhaustive list of publications

2024


Tridon C, Bachelet D, El Baied M, Eloy P, Ortuno S, Para M, Wicky PH, Vellieux G, de Montmollin E, Bouadma L, Manceau H, Timsit JF, Peoc'h K, Sonneville R
Association of Sepsis With Neurologic Outcomes of Adult Patients Treated With Venoarterial Extracorporeal Membrane Oxygnenation.
Critical Care Explorations 2024, 6, e1042.

2023


Gault N, Bachelet D, Laouénan C, Borie R, Cracowski C, Poissy J, Faure K, Lainé F, Lefèvre B, Isnard M, Patrier J, Launay O, Costagliola D, Ghosn J, Bouadma L, French COVID Cohort Study Group and The French COVID Investigators Study Group
Impact of corticosteroids use on midterm sequelae in survivors of COVID-19 admitted to hospital: A prospective cohort study.
Journal of Medical Virology 2023, 95, e28819.

Hocini H, Wiedemann A, Blengio F, Lefebvre C, Cervantes-Gonzalez M, Foucat E, Tisserand P, Surenaud M, Coléon S, Prague M, Guillaumat L, Krief C, Fenwick C, Laouénan C, Bouadma L, Ghosn J, Pantaleo G, Thiébaut R, French COVID cohort study group, Lévy Y
Neutrophil Activation and Immune Thrombosis Profiles Persist in Convalescent COVID-19.
Journal of Clinical Immunology 2023, 43, 882-893.

Dumont M, Guilhou T, Gerin M, Frémont-Goudot G, Nivose PL, Koubbi A, Joly V, Bouadma L, Yazdanpanah Y, André MH, de La Porte des Vaux C
Myocarditis in monkeypox-infected patients: a case series.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2023, 29, 390.e5-390.e7.

Stern J, Dupuis C, Kpeglo H, Reuter J, Vinclair C, Para M, Nataf P, Pelletier AL, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Upper gastrointestinal bleeding in adults treated with veno-arterial extracorporeal membrane oxygenation: a cohort study.
European Journal of Cardio-Thoracic Surgery: Official Journal of the European Association for Cardio-Thoracic Surgery 2023, 63, ezad083.

Thy M, de Montmollin E, Bouadma L, Timsit JF, Sonneville R
Severe meningoencephalitis: epidemiology and outcomes.
Current Opinion in Critical Care 2023, 29, 415-422.

Chevret S, Bouadma L, Dupuis C, Burdet C, Timsit JF, COVIDICUS RCT group
Which severe COVID-19 patients could benefit from high dose dexamethasone? A Bayesian post-hoc reanalysis of the COVIDICUS randomized clinical trial.
Annals of Intensive Care 2023, 13, 75.

2022


Bouadma L, Mekontso-Dessap A, Burdet C, Merdji H, Poissy J, Dupuis C, Guitton C, Schwebel C, Cohen Y, Bruel C, Marzouk M, Geri G, Cerf C, Mégarbane B, Garçon P, Kipnis E, Visseaux B, Beldjoudi N, Chevret S, Timsit JF, COVIDICUS Study Group
High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure: The COVIDICUS Randomized Clinical Trial.
JAMA internal medicine 2022, 182, 906-916.

Blot S, Ruppé E, Harbarth S, Asehnoune K, Poulakou G, Luyt CE, Rello J, Klompas M, Depuydt P, Eckmann C, Martin-Loeches I, Povoa P, Bouadma L, Timsit JF, Zahar JR
Healthcare-associated infections in adult intensive care unit patients: Changes in epidemiology, diagnosis, prevention and contributions of new technologies.
Intensive & Critical Care Nursing 2022, 70, 103227.

Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Michailidis E, Hoffmann HH, Eto S, Garcia-Prat M, Bizien L, Parra-Martínez A, Yang R, Haljasmägi L, Migaud M, Särekannu K, Maslovskaja J, de Prost N, Tandjaoui-Lambiotte Y, Luyt CE, Amador-Borrero B, Gaudet A, Poissy J, Morel P, Richard P, Cognasse F, Troya J, Trouillet-Assant S, Belot A, Saker K, Garçon P, Rivière JG, Lagier JC, Gentile S, Rosen LB, Shaw E, Morio T, Tanaka J, Dalmau D, Tharaux PL, Sene D, Stepanian A, Mégarbane B, Triantafyllia V, Fekkar A, Heath JR, Franco JL, Anaya JM, Solé-Violán J, Imberti L, Biondi A, Bonfanti P, Castagnoli R, Delmonte OM, Zhang Y, Snow AL, Holland SM, Biggs CM, Moncada-Vélez M, Arias AA, Lorenzo L, Boucherit S, Anglicheau D, Planas AM, Haerynck F, Duvlis S, Ozcelik T, Keles S, Bousfiha AA, El Bakkouri J, Ramirez-Santana C, Paul S, Pan-Hammarström Q, Hammarström L, Dupont A, Kurolap A, Metz CN, Aiuti A, Casari G, Lampasona V, Ciceri F, Barreiros LA, Dominguez-Garrido E, Vidigal M, Zatz M, van de Beek D, Sahanic S, Tancevski I, Stepanovskyy Y, Boyarchuk O, Nukui Y, Tsumura M, Vidaur L, Tangye SG, Burrel S, Duffy D, Quintana-Murci L, Klocperk A, Kann NY, Shcherbina A, Lau YL, Leung D, Coulongeat M, Marlet J, Koning R, Reyes LF, Chauvineau-Grenier A, Venet F, Monneret G, Nussenzweig MC, Arrestier R, Boudhabhay I, Baris-Feldman H, Hagin D, Wauters J, Meyts I, Dyer AH, Kennelly SP, Bourke NM, Halwani R, Sharif-Askari FS, Dorgham K, Sallette J, Sedkaoui SM, AlKhater S, Rigo-Bonnin R, Morandeira F, Roussel L, Vinh DC, Erikstrup C, Condino-Neto A, Prando C, Bondarenko A, Spaan AN, Gilardin L, Fellay J, Lyonnet S, Bilguvar K, Lifton RP, Mane S, HGID Lab, COVID Clinicians, COVID-STORM Clinicians, NIAID Immune Response to COVID Group, NH-COVAIR Study Group, Danish CHGE, Danish Blood Donor Study, St. James's Hospital, SARS CoV2 Interest Group, French COVID Cohort Study Group, Imagine COVID-Group, Milieu Intérieur Consortium, CoV-Contact Cohort, Amsterdam UMC Covid-19 Biobank Investigators, COVID Human Genetic Effort, CP-COVID-19 Group, CONSTANCES cohort, 3C-Dijon Study, Cerba Health-Care, Etablissement Français du Sang Study group, Anderson MS, Boisson B, Béziat V, Zhang SY, Andreakos E, Hermine O, Pujol A, Peterson P, Mogensen TH, Rowen L, Mond J, Debette S, de Lamballerie X, Burdet C, Bouadma L, Zins M, Soler-Palacin P, Colobran R, Gorochov G, Solanich X, Susen S, Martinez-Picado J, Raoult D, Vasse M, Gregersen PK, Piemonti L, Rodríguez-Gallego C, Notarangelo LD, Su HC, Kisand K, Okada S, Puel A, Jouanguy E, Rice CM, Tiberghien P, Zhang Q, Casanova JL, Abel L, Cobat A
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies.
Proceedings of the National Academy of Sciences of the United States of America 2022, 119, e2200413119.

Abid S, Papin G, Vellieux G, de Montmollin E, Wicky PH, Patrier J, Jaquet P, Bouadma L, Rouvel-Tallec A, Timsit JF, Sonneville R
A Simplified Electroencephalography Montage and Interpretation for Evaluation of Comatose Patients in the ICU.
Critical Care Explorations 2022, 4, e0781.

Jaquet P, Legouy C, Le Fevre L, Grinea A, Sinnah F, Franchineau G, Patrier J, Marzouk M, Wicky PH, Alexis Geoffroy P, Arnoult F, Vledouts S, de Montmollin E, Bouadma L, Timsit JF, Sharshar T, Sonneville R
Neurologic Outcomes of Survivors of COVID-19-Associated Acute Respiratory Distress Syndrome Requiring Intubation.
Critical Care Medicine 2022, 50, e674-e682.

Patrier J, Villageois-Tran K, Szychowiak P, Ruckly S, Gschwind R, Wicky PH, Gueye S, Armand-Lefevre L, Marzouk M, Sonneville R, Bouadma L, Petitjean M, Lamara F, de Montmollin E, Timsit JF, Ruppé E, French COVID Cohort Study Group
Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults.
Critical Care (London, England) 2022, 26, 300.

Soum E, Timsit JF, Ruckly S, Gruson D, Canet E, Klouche K, Argaud L, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Darmon M, Bohé J, Schwebel C, Bouadma L, Dupuis C, Souweine B, Lautrette A
Predictive factors for severe long-term chronic kidney disease after acute kidney injury requiring renal replacement therapy in critically ill patients: an ancillary study of the ELVIS randomized controlled trial.
Critical Care (London, England) 2022, 26, 367.

Goletto T, Decaux S, Bunel V, Weisenburger G, Messika J, Najem S, Medraoui C, Godet C, Debray MP, Lortat-Jacob B, Mordant P, Castier Y, Bouadma L, Borie R, Mal H
Acute worsening of native lung fibrosis after single lung transplantation for pulmonary fibrosis: two case reports.
Journal of Medical Case Reports 2022, 16, 2.

Egea A, Dupuis C, de Montmollin E, Wicky PH, Patrier J, Jaquet P, Lefèvre L, Sinnah F, Marzouk M, Sonneville R, Bouadma L, Souweine B, Timsit JF
Augmented renal clearance in the ICU: estimation, incidence, risk factors and consequences-a retrospective observational study.
Annals of Intensive Care 2022, 12, 88.

Rambaud T, de Montmollin E, Jaquet P, Gaudemer A, Mariotte E, Abid S, Para M, Cimadevilla C, Iung B, Duval X, Wolff M, Bouadma L, Timsit JF, Sonneville R
Cerebrovascular complications and outcomes of critically ill adult patients with infective endocarditis.
Annals of Intensive Care 2022, 12, 119.

de Montmollin E, Peoc'h K, Marzouk M, Ruckly S, Wicky PH, Patrier J, Jaquet P, Sonneville R, Bouadma L, Timsit JF
Mid-Regional Pro-Adrenomedullin as a Prognostic Factor for Severe COVID-19 ARDS.
Antibiotics (Basel, Switzerland) 2022, 11, 1166.

2021


Ader F, Peiffer-Smadja N, Poissy J, Bouscambert-Duchamp M, Belhadi D, Diallo A, Delmas C, Saillard J, Dechanet A, Mercier N, Dupont A, Alfaiate T, Lescure FX, Raffi F, Goehringer F, Kimmoun A, Jaureguiberry S, Reignier J, Nseir S, Danion F, Clere-Jehl R, Bouiller K, Navellou JC, Tolsma V, Cabié A, Dubost C, Courjon J, Leroy S, Mootien J, Gaci R, Mourvillier B, Faure E, Pourcher V, Gallien S, Launay O, Lacombe K, Lanoix JP, Makinson A, Martin-Blondel G, Bouadma L, Botelho-Nevers E, Gagneux-Brunon A, Epaulard O, Piroth L, Wallet F, Richard JC, Reuter J, Staub T, Lina B, Noret M, Andrejak C, Lê MP, Peytavin G, Hites M, Costagliola D, Yazdanpanah Y, Burdet C, Mentré F, DisCoVeRy study group
An open-label randomized controlled trial of the effect of lopinavir/ritonavir, lopinavir/ritonavir plus IFN-β-1a and hydroxychloroquine in hospitalized patients with COVID-19.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2021, 27, 1826-1837.

Lévy Y, Wiedemann A, Hejblum BP, Durand M, Lefebvre C, Surénaud M, Lacabaratz C, Perreau M, Foucat E, Déchenaud M, Tisserand P, Blengio F, Hivert B, Gauthier M, Cervantes-Gonzalez M, Bachelet D, Laouénan C, Bouadma L, Timsit JF, Yazdanpanah Y, Pantaleo G, Hocini H, Thiébaut R, French COVID cohort study group
CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death.
iScience 2021, 24, 102711.

Crescenzo-Chaigne B, Behillil S, Enouf V, Escriou N, Petres S, Ungeheuer MN, Ghosn J, Tubiana S, Bouadma L, van der Werf S, Demeret C, French COVID cohort study group
Nasopharyngeal and serological anti SARS-CoV-2 IgG/IgA responses in COVID-19 patients.
Journal of Clinical Virology Plus 2021, 1, 100041.

Lefrancq N, Paireau J, Hozé N, Courtejoie N, Yazdanpanah Y, Bouadma L, Boëlle PY, Chereau F, Salje H, Cauchemez S
Evolution of outcomes for patients hospitalised during the first 9 months of the SARS-CoV-2 pandemic in France: A retrospective national surveillance data analysis.
The Lancet Regional Health. Europe 2021, 5, 100087.

Fournier M, Faille D, Dossier A, Mageau A, Nicaise Roland P, Ajzenberg N, Borie R, Bouadma L, Bunel V, Castier Y, Choquet C, Crestani B, Daugas E, Deconinck L, Descamps D, Descamps V, Dieudé P, Ducrocq G, Faucher N, Goulenok T, Guidoux C, Khalil A, Lavallée P, Lescure FX, Lortat-Jacob B, Mal H, Mutuon P, Pellenc Q, Steg PG, Taille C, Timsit JF, Yazdanpanah Y, Papo T, Sacré K
Arterial Thrombotic Events in Adult Inpatients With COVID-19.
Mayo Clinic Proceedings 2021, 96, 295-303.

Crawford C, Vanoli E, Decorde B, Lancelot M, Duprat C, Josserand C, Jilesen J, Bouadma L, Timsit JF
Modeling of aerosol transmission of airborne pathogens in ICU rooms of COVID-19 patients with acute respiratory failure.
Scientific Reports 2021, 11, 11778.

Heilmann E, Gregoriano C, Annane D, Reinhart K, Bouadma L, Wolff M, Chastre J, Luyt CE, Tubach F, Branche AR, Briel M, Christ-Crain M, Welte T, Corti C, de Jong E, Nijsten M, de Lange DW, van Oers JAH, Beishuizen A, Girbes ARJ, Deliberato RO, Schroeder S, Kristoffersen KB, Layios N, Damas P, Lima SSS, Nobre V, Wei L, Oliveira CF, Shehabi Y, Stolz D, Tamm M, Verduri A, Wang JX, Drevet S, Gavazzi G, Mueller B, Schuetz P
Duration of antibiotic treatment using procalcitonin-guided treatment algorithms in older patients: a patient-level meta-analysis from randomized controlled trials.
Age and Ageing 2021, 50, 1546-1556.

Buetti N, Patrier J, Le Hingrat Q, Loiodice A, Bouadma L, Visseaux B, Timsit JF
Risk Factors for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Detection in Blood of Critically Ill Patients.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2021, 72, e690-e691.

Dupuis C, Le Bihan C, Maubon D, Calvet L, Ruckly S, Schwebel C, Bouadma L, Azoulay E, Cornet M, Timsit JF, Empiricus Study Group
Performance of Repeated Measures of (1-3)-β-D-Glucan, Mannan Antigen, and Antimannan Antibodies for the Diagnosis of Invasive Candidiasis in ICU Patients: A Preplanned Ancillary Analysis of the EMPIRICUS Randomized Clinical Trial.
Open Forum Infectious Diseases 2021, 8, ofab080.

Dupuis C, Bouadma L, de Montmollin E, Goldgran-Toledano D, Schwebel C, Reignier J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Grapin K, Laurent V, Buetti N, Gainnier M, Souweine B, Timsit JF
Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia.
Critical Care Explorations 2021, 3, e0329.

Legouy C, Girard-Stein L, Wanono R, de Montmollin E, Vellieux G, Bouadma L, Dupuis C, Abid S, Vinclair C, Ruckly S, Rouvel-Tallec A, d'Ortho MP, Timsit JF, Sonneville R
Association of Standard Electroencephalography Findings With Mortality and Command Following in Mechanically Ventilated Patients Remaining Unresponsive After Sedation Interruption.
Critical Care Medicine 2021, 49, e423-e432.

Niederman MS, Baron RM, Bouadma L, Calandra T, Daneman N, DeWaele J, Kollef MH, Lipman J, Nair GB
Initial antimicrobial management of sepsis.
Critical Care (London, England) 2021, 25, 307.

Meyer A, Buetti N, Houhou-Fidouh N, Patrier J, Abdel-Nabey M, Jaquet P, Presente S, Girard T, Sayagh F, Ruckly S, Wicky PH, de Montmollin E, Bouadma L, Sonneville R, Descamps D, Timsit JF
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients.
Critical Care (London, England) 2021, 25, 417.

Lemiale V, Dumas G, Demoule A, Pène F, Kouatchet A, Bisbal M, Nseir S, Argaud L, Kontar L, Klouche K, Barbier F, Seguin A, Louis G, Constantin JM, Mayaux J, Wallet F, Peigne V, Girault C, Oziel J, Nyunga M, Terzi N, Bouadma L, Lautrette A, Bige N, Raphalen JH, Papazian L, Bruneel F, Lebert C, Benoit D, Meert AP, Jaber S, Mokart D, Darmon M, Azoulay E, Groupe de Recherche en Reanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)
Performance of the ROX index to predict intubation in immunocompromised patients receiving high-flow nasal cannula for acute respiratory failure.
Annals of Intensive Care 2021, 11, 17.

Touchard C, Cartailler J, Vellieux G, de Montmollin E, Jaquet P, Wanono R, Reuter J, Para M, Bouadma L, Timsit JF, d'Ortho MP, Kubis N, Rouvel Tallec A, Sonneville R, DINAMO Study Group
Simplified frontal EEG in adults under veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2021, 11, 76.

Travert B, Dossier A, Jamme M, Cointe A, Delmas Y, Malot S, Wynckel A, Seguin A, Presne C, Hie M, Benhamou Y, Ribes D, Choukroun G, Grangé S, Hertig A, Le Gall EC, Galicier L, Daugas E, Bouadma L, Weill FX, Azoulay E, Fakhouri F, Veyradier A, Bonacorsi S, Hogan J, Frémeaux-Bacchi V, Rondeau E, Mariani-Kurkdjian P, Coppo P, Centre de Référence des Microangiopathies Thrombotiques2
Shiga Toxin-Associated Hemolytic Uremic Syndrome in Adults, France, 2009-2017.
Emerging Infectious Diseases 2021, 27, 1876-1885.

Ursino M, Dupuis C, Buetti N, de Montmollin E, Bouadma L, Golgran-Toledano D, Ruckly S, Neuville M, Cohen Y, Mourvillier B, Souweine B, Gainnier M, Laurent V, Terzi N, Shiami S, Reignier J, Alberti C, Timsit JF, On Behalf Of The Outcomerea Study Group n
Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients.
Journal of Clinical Medicine 2021, 10,

2020


Barbier F, Mer M, Szychowiak P, Miller RF, Mariotte É, Galicier L, Bouadma L, Tattevin P, Azoulay É
Management of HIV-infected patients in the intensive care unit.
Intensive Care Medicine 2020, 46, 329-342.

Bouadma L, Lescure FX, Lucet JC, Yazdanpanah Y, Timsit JF
Severe SARS-CoV-2 infections: practical considerations and management strategy for intensivists.
Intensive Care Medicine 2020, 46, 579-582.

Andremont O, Armand-Lefevre L, Dupuis C, de Montmollin E, Ruckly S, Lucet JC, Smonig R, Magalhaes E, Ruppé E, Mourvillier B, Lebut J, Lermuzeaux M, Sonneville R, Bouadma L, Timsit JF, COMBACTE net consortium
Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.
Intensive Care Medicine 2020, 46, 1232-1242.

Luyt CE, Bouadma L, Morris AC, Dhanani JA, Kollef M, Lipman J, Martin-Loeches I, Nseir S, Ranzani OT, Roquilly A, Schmidt M, Torres A, Timsit JF
Pulmonary infections complicating ARDS.
Intensive Care Medicine 2020, 46, 2168-2183.

Bouadma L, Wiedemann A, Patrier J, Surénaud M, Wicky PH, Foucat E, Diehl JL, Hejblum BP, Sinnah F, de Montmollin E, Lacabaratz C, Thiébaut R, Timsit JF, Lévy Y
Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome.
Journal of Clinical Immunology 2020, 40, 1082-1092.

Magalhaes E, Reuter J, Wanono R, Bouadma L, Jaquet P, Tanaka S, Sinnah F, Ruckly S, Dupuis C, de Montmollin E, Para M, Braham W, Pisani A, d'Ortho MP, Rouvel-Tallec A, Timsit JF, Sonneville R, DINAMO study group
Early EEG for Prognostication Under Venoarterial Extracorporeal Membrane Oxygenation.
Neurocritical Care 2020, 33, 688-694.

Peiffer-Smadja N, Lucet JC, Bendjelloul G, Bouadma L, Gerard S, Choquet C, Jacques S, Khalil A, Maisani P, Casalino E, Descamps D, Timsit JF, Yazdanpanah Y, Lescure FX
Challenges and issues about organising a hospital to respond to the COVID-19 outbreak: experience from a French reference centre.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020

Hingrat QL, Visseaux B, Laouenan C, Tubiana S, Bouadma L, Yazdanpanah Y, Duval X, Burdet C, Ichou H, Damond F, Bertine M, Benmalek N, Choquet C, Timsit JF, Ghosn J, Charpentier C, Descamps D, Houhou-Fidouh N, French COVID cohort management committee, CoV-CONTACT study group, members of the French-COVID cohort study group (by alphabetical order), member of the CoV-CONTACT study group. Principal investigator, Steering Committee, CoV-CONTACT Clinical Centers, Coordination and statistical analyses, Virological Lab, Biological Center, Partners, Sponsor, Genetic
Detection of SARS-CoV-2 N-antigen in blood during acute COVID-19 provides a sensitive new marker and new testing alternatives.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020, S1198-743X(20)30721-7.

Benchetrit L, Mathy V, Armand-Lefevre L, Bouadma L, Timsit JF
Successful treatment of septic shock due to NDM-1-producing Klebsiella pneumoniae using ceftazidime/avibactam combined with aztreonam in solid organ transplant recipients: report of two cases.
International Journal of Antimicrobial Agents 2020, 55, 105842.

Dubert M, Visseaux B, Isernia V, Bouadma L, Deconinck L, Patrier J, Wicky PH, Le Pluart D, Kramer L, Rioux C, Le Hingrat Q, Houhou-Fidouh N, Yazdanpanah Y, Ghosn J, Lescure FX
Case report study of the first five COVID-19 patients treated with remdesivir in France.
International Journal of Infectious Diseases 2020, 98, 290-293.

Jolivet S, Lolom I, Bailly S, Bouadma L, Lortat-Jacob B, Montravers P, Armand-Lefevre L, Timsit JF, Lucet JC
Impact of colonization pressure on acquisition of extended-spectrum β-lactamase-producing Enterobacterales and meticillin-resistant Staphylococcus aureus in two intensive care units: a 19-year retrospective surveillance.
The Journal of Hospital Infection 2020, 105, 10-16.

Ibn Saied W, Merceron S, Schwebel C, Le Monnier A, Oziel J, Garrouste-Orgeas M, Marcotte G, Ruckly S, Souweine B, Darmon M, Bouadma L, de Montmollin E, Mourvillier B, Reignier J, Papazian L, Siami S, Azoulay E, Bédos JP, Timsit JF
Ventilator-associated pneumonia due to Stenotrophomonas maltophilia: Risk factors and outcome.
The Journal of Infection 2020, 80, 279-285.

Lescure FX, Bouadma L, Nguyen D, Parisey M, Wicky PH, Behillil S, Gaymard A, Bouscambert-Duchamp M, Donati F, Le Hingrat Q, Enouf V, Houhou-Fidouh N, Valette M, Mailles A, Lucet JC, Mentre F, Duval X, Descamps D, Malvy D, Timsit JF, Lina B, van-der-Werf S, Yazdanpanah Y
Clinical and virological data of the first cases of COVID-19 in Europe: a case series.
The Lancet. Infectious Diseases 2020, 20, 697-706.

Lê MP, Jaquet P, Patrier J, Wicky PH, Le Hingrat Q, Veyrier M, Kauv J, Sonneville R, Visseaux B, Laouénan C, Bouadma L, Descamps D, de Montmollin E, Peytavin G, Timsit JF
Pharmacokinetics of lopinavir/ritonavir oral solution to treat COVID-19 in mechanically ventilated ICU patients.
The Journal of Antimicrobial Chemotherapy 2020, 75, 2657-2660.

Reuter J, Peoc'h K, Bouadma L, Ruckly S, Chicha-Cattoir V, Faille D, Bourrienne MC, Dupuis C, Magalhaes E, Tanaka S, Vinclair C, de Montmollin E, Mazighi M, Para M, Braham W, Pisani A, Ajzenberg N, Timsit JF, Sonneville R
Neuron-Specific Enolase Levels in Adults Under Venoarterial Extracorporeal Membrane Oxygenation.
Critical Care Explorations 2020, 2, e0239.

Baudry G, Sonneville R, Waintraub X, Lebreton G, Deguillard C, Mertens E, Bouadma L, Demondion P, Bréchot N, Luyt CE, Extramiana F, Hékimian G, Dupuis C, Para M, Pisani A, Braham W, Gandjbakhch E, Leenhardt A, Timsit JF, Leprince P, Combes A, Schmidt M
Extracorporeal Membrane Oxygenation to Support Life-Threatening Drug-Refractory Electrical Storm.
Critical Care Medicine 2020, 48, e856-e863.

Grzelak L, Temmam S, Planchais C, Demeret C, Tondeur L, Huon C, Guivel-Benhassine F, Staropoli I, Chazal M, Dufloo J, Planas D, Buchrieser J, Rajah MM, Robinot R, Porrot F, Albert M, Chen KY, Crescenzo-Chaigne B, Donati F, Anna F, Souque P, Gransagne M, Bellalou J, Nowakowski M, Backovic M, Bouadma L, Le Fevre L, Le Hingrat Q, Descamps D, Pourbaix A, Laouénan C, Ghosn J, Yazdanpanah Y, Besombes C, Jolly N, Pellerin-Fernandes S, Cheny O, Ungeheuer MN, Mellon G, Morel P, Rolland S, Rey FA, Behillil S, Enouf V, Lemaitre A, Créach MA, Petres S, Escriou N, Charneau P, Fontanet A, Hoen B, Bruel T, Eloit M, Mouquet H, Schwartz O, van der Werf S
A comparison of four serological assays for detecting anti-SARS-CoV-2 antibodies in human serum samples from different populations.
Science Translational Medicine 2020, 12,

Bailly S, Gautier-Veyret E, Lê MP, Bouadma L, Andremont O, Neuville M, Mourvillier B, Sonneville R, Magalhaes E, Lebut J, Radjou A, Smonig R, Wolff M, Massias L, Dupuis C, Timsit JF
Impact of Loading Dose of Caspofungin in Pharmacokinetic-Pharmacodynamic Target Attainment for Severe Candidiasis Infections in Patients in Intensive Care Units: the CASPOLOAD Study.
Antimicrobial Agents and Chemotherapy 2020, 64, e01545-20.

Visseaux B, Le Hingrat Q, Collin G, Bouzid D, Lebourgeois S, Le Pluart D, Deconinck L, Lescure FX, Lucet JC, Bouadma L, Timsit JF, Descamps D, Yazdanpanah Y, Casalino E, Houhou-Fidouh N, McAdam AJ
Evaluation of the QIAstat-Dx Respiratory SARS-CoV-2 Panel, the First Rapid Multiplex PCR Commercial Assay for SARS-CoV-2 Detection.
Journal of Clinical Microbiology 2020, 58, e00630-20, /jcm/58/8/JCM.00630-20.atom.

Peiffer-Smadja N, Bouadma L, Mathy V, Allouche K, Patrier J, Reboul M, Montravers P, Timsit JF, Armand-Lefevre L
Performance and impact of a multiplex PCR in ICU patients with ventilator-associated pneumonia or ventilated hospital-acquired pneumonia.
Critical Care (London, England) 2020, 24, 366.

Buetti N, Ruckly S, Lucet JC, Bouadma L, Garrouste-Orgeas M, Schwebel C, Mimoz O, Souweine B, Timsit JF
Local signs at insertion site and catheter-related bloodstream infections: an observational post hoc analysis using individual data of four RCTs.
Critical Care (London, England) 2020, 24, 694.

Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.

Buetti N, Ruckly S, Lucet JC, Bouadma L, Schwebel C, Mimoz O, Timsit JF
Ultrasound guidance and risk for intravascular catheter-related infections among peripheral arterial catheters: a post-hoc analysis of two large randomized-controlled trials.
Annals of Intensive Care 2020, 10, 89.

Elabbadi A, Pichon J, Visseaux B, Schnuriger A, Bouadma L, Philippot Q, Patrier J, Labbé V, Ruckly S, Fartoukh M, Timsit JF, Voiriot G
Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study).
Annals of Intensive Care 2020, 10, 123.

Dupuis C, Bouadma L, Ruckly S, Perozziello A, Van-Gysel D, Mageau A, Mourvillier B, de Montmollin E, Bailly S, Papin G, Sinnah F, Vinclair C, Abid S, Sonneville R, Timsit JF
Sepsis and septic shock in France: incidences, outcomes and costs of care.
Annals of Intensive Care 2020, 10, 145.

Sonneville R, Smonig R, Dupuis C, Bouadma L, de Montmollin E, Timsit JF
Natural light exposure and delirium in ICU: does the dark side cloud everything?.
Annals of Intensive Care 2020, 10, 25.

Borie R, Savale L, Dossier A, Ghosn J, Taillé C, Visseaux B, Jebreen K, Diallo A, Tesmoingt C, Morer L, Goletto T, Faucher N, Hajouji L, Neukirch C, Phillips M, Stelianides S, Bouadma L, Brosseau S, Ottaviani S, Pluvy J, Le Pluart D, Debray MP, Raynaud-Simon A, Descamps D, Khalil A, Timsit JF, Lescure FX, Descamps V, Papo T, Humbert M, Crestani B, Dieude P, Vicaut E, Zalcman G, Bichat & Kremlin-Bicêtre AP-HP COVID teams
Glucocorticoids with low-dose anti-IL1 anakinra rescue in severe non-ICU COVID-19 infection: A cohort study.
PloS One 2020, 15, e0243961.

Heilmann E, Gregoriano C, Wirz Y, Luyt CE, Wolff M, Chastre J, Tubach F, Christ-Crain M, Bouadma L, Annane D, Damas P, Kristoffersen KB, Oliveira CF, Stolz D, Tamm M, de Jong E, Reinhart K, Shehabi Y, Verduri A, Nobre V, Nijsten M, deLange DW, van Oers JAH, Beishuizen A, Girbes ARJ, Mueller B, Schuetz P
Association of kidney function with effectiveness of procalcitonin-guided antibiotic treatment: a patient-level meta-analysis from randomized controlled trials.
Clinical Chemistry and Laboratory Medicine 2020, 59, 441-453.

2019


Garrouste-Orgeas M, Flahault C, Vinatier I, Rigaud JP, Thieulot-Rolin N, Mercier E, Rouget A, Grand H, Lesieur O, Tamion F, Hamidfar R, Renault A, Parmentier-Decrucq E, Monseau Y, Argaud L, Bretonnière C, Lautrette A, Badié J, Boulet E, Floccard B, Forceville X, Kipnis E, Soufir L, Valade S, Bige N, Gaffinel A, Hamzaoui O, Simon G, Thirion M, Bouadma L, Large A, Mira JP, Amdjar-Badidi N, Jourdain M, Jost PH, Maxime V, Santoli F, Ruckly S, Vioulac C, Leborgne MA, Bellalou L, Fasse L, Misset B, Bailly S, Timsit JF
Effect of an ICU Diary on Posttraumatic Stress Disorder Symptoms Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.
JAMA 2019, 322, 229-239.

Papin G, Sonneville R, Nataf P, Bouadma L
Emergency craniotomy in semi-lateral position for posterior fossa hemorrhage evacuation under venoarterial extracorporeal membrane oxygenation.
Intensive Care Medicine 2019, 45, 1152-1153.

Jaquet P, de Montmollin E, Dupuis C, Sazio C, Conrad M, Susset V, Demeret S, Tadie JM, Argaud L, Barbier F, Sarton B, Chabane R, Daubin D, Brulé N, Lerolle N, Alves M, Da Silva D, Kalioubi AE, Silva S, Bailly P, Wolff M, Bouadma L, Timsit JF, Sonneville R, ENCEPHALITICA study group
Functional outcomes in adult patients with herpes simplex encephalitis admitted to the ICU: a multicenter cohort study.
Intensive Care Medicine 2019, 45, 1103-1111.

for the EUVAE Study Group, Rello J, Ramírez-Estrada S, Romero A, Arvaniti K, Koulenti D, Nseir S, Oztoprak N, Bouadma L, Vidaur L, Lagunes L, Peña-López Y
Factors associated with ventilator-associated events: an international multicenter prospective cohort study.
European Journal of Clinical Microbiology & Infectious Diseases 2019, 38, 1693-1699.

Mageau A, Timsit JF, Perrozziello A, Ruckly S, Dupuis C, Bouadma L, Papo T, Sacre K
The burden of chronic kidney disease in systemic lupus erythematosus: A nationwide epidemiologic study.
Autoimmunity Reviews 2019, 18, 733-737.

Mageau A, Sacré K, Perozziello A, Ruckly S, Dupuis C, Bouadma L, Papo T, Timsit JF
Septic shock among patients with systemic lupus erythematosus: short and long-term outcome. Analysis of a French nationwide database.
The Journal of Infection 2019

Meier MA, Branche A, Neeser OL, Wirz Y, Haubitz S, Bouadma L, Wolff M, Luyt CE, Chastre J, Tubach F, Christ-Crain M, Corti C, Jensen JUS, Deliberato RO, Kristoffersen KB, Damas P, Nobre V, Oliveira CF, Shehabi Y, Stolz D, Tamm M, Mueller B, Schuetz P
Procalcitonin-guided Antibiotic Treatment in Patients With Positive Blood Cultures: A Patient-level Meta-analysis of Randomized Trials.
Clinical Infectious Diseases 2019, 69, 388-396.

Ibn Saied W, Mourvillier B, Cohen Y, Ruckly S, Reignier J, Marcotte G, Siami S, Bouadma L, Darmon M, de Montmollin E, Argaud L, Kallel H, Garrouste-Orgeas M, Soufir L, Schwebel C, Souweine B, Glodgran-Toledano D, Papazian L, Timsit JF
A Comparison of the Mortality Risk Associated With Ventilator-Acquired Bacterial Pneumonia and Nonventilator ICU-Acquired Bacterial Pneumonia*:.
Critical Care Medicine 2019, 47, 345-352.

Dumas G, Demoule A, Mokart D, Lemiale V, Nseir S, Argaud L, Pène F, Kontar L, Bruneel F, Klouche K, Barbier F, Reignier J, Stoclin A, Louis G, Constantin JM, Wallet F, Kouatchet A, Peigne V, Perez P, Girault C, Jaber S, Cohen Y, Nyunga M, Terzi N, Bouadma L, Lebert C, Lautrette A, Bigé N, Raphalen JH, Papazian L, Benoit D, Darmon M, Chevret S, Azoulay E
Center effect in intubation risk in critically ill immunocompromised patients with acute hypoxemic respiratory failure.
Critical Care 2019, 23, 306.

Bouadma L, Darmon M, Argaud L, Vinclair C, Siami S, Garrouste-Orgeas M, Papazian L, Cohen Y, Marcotte G, Styfalova L, Reignier J, Lautrette A, Schwebel C, Timsit JF
Influence of dyskalemia at admission and early dyskalemia correction on survival and cardiac events of critically ill patients.
Critical Care 2019, 23,

Pons S, Sonneville R, Bouadma L, Styfalova L, Ruckly S, Neuville M, Radjou A, Lebut J, Dilly MP, Mourvillier B, Dorent R, Nataf P, Wolff M, Timsit JF
Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation.
Annals of Intensive Care 2019, 9, 17.

Smonig R, Magalhaes E, Bouadma L, Andremont O, de Montmollin E, Essardy F, Mourvillier B, Lebut J, Dupuis C, Neuville M, Lermuzeaux M, Timsit JF, Sonneville R
Impact of natural light exposure on delirium burden in adult patients receiving invasive mechanical ventilation in the ICU: a prospective study.
Annals of Intensive Care 2019, 9, 120.

2018


Bouadma L, Karpanen T, Elliott T
Chlorhexidine use in adult patients on ICU.
Intensive Care Medicine 2018, 44, 2232-2234.

Kindermans M, Abid S, Alkhoder S, Bouadma L
Pulsatile bleeding after sternal bone marrow puncture.
Intensive Care Medicine 2018, 44, 1758-1759.

Bouadma L, Klompas M
Oral care with chlorhexidine: beware!.
Intensive Care Medicine 2018, 44, 1153-1155.

Leone M, Bouadma L, Bouhemad B, Brissaud O, Dauger S, Gibot S, Hraiech S, Jung B, Kipnis E, Launey Y, Luyt CE, Margetis D, Michel F, Mokart D, Montravers P, Monsel A, Nseir S, Pugin J, Roquilly A, Velly L, Zahar JR, Bruyère R, Chanques G
Hospital-acquired pneumonia in ICU.
Anaesthesia, Critical Care & Pain Medicine 2018, 37, 83-98.

Combes A, Hajage D, Capellier G, Demoule A, Lavoué S, Guervilly C, Da Silva D, Zafrani L, Tirot P, Veber B, Maury E, Levy B, Cohen Y, Richard C, Kalfon P, Bouadma L, Mehdaoui H, Beduneau G, Lebreton G, Brochard L, Ferguson ND, Fan E, Slutsky AS, Brodie D, Mercat A, EOLIA Trial Group, REVA, and ECMONet
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome.
The New England Journal of Medicine 2018, 378, 1965-1975.

Cantier M, Morisot A, Guérot E, Megarbane B, Razazi K, Contou D, Mariotte E, Canet E, De Montmollin E, Dubée V, Boulet E, Gaudry S, Voiriot G, Mayaux J, Pène F, Neuville M, Mourvillier B, Ruckly S, Bouadma L, Wolff M, Timsit JF, Sonneville R, ENCEPHALITICA study group
Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study.
Critical Care (London, England) 2018, 22, 210.

Truche AS, Ragey SP, Souweine B, Bailly S, Zafrani L, Bouadma L, Clec'h C, Garrouste-Orgeas M, Lacave G, Schwebel C, Guebre-Egziabher F, Adrie C, Dumenil AS, Zaoui P, Argaud L, Jamali S, Goldran Toledano D, Marcotte G, Timsit JF, Darmon M
ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients.
Annals of Intensive Care 2018, 8, 127.

2017


Sonneville R, Gimenez L, Labreuche J, Smonig R, Magalhaes E, Bouadma L, Timsit JF, Mazighi M
What is the prognosis of acute stroke patients requiring ICU admission?.
Intensive Care Medicine 2017, 43, 271-272.

Loubet P, Voiriot G, Houhou-Fidouh N, Neuville M, Bouadma L, Lescure FX, Descamps D, Timsit JF, Yazdanpanah Y, Visseaux B
Impact of respiratory viruses in hospital-acquired pneumonia in the intensive care unit: A single-center retrospective study.
Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology 2017, 91, 52-57.

Dupuis C, Garrouste-Orgeas M, Bailly S, Adrie C, Goldgran-Toledano D, Azoulay E, Ruckly S, Marcotte G, Souweine B, Darmon M, Cohen Y, Schwebel C, Lacave G, Bouadma L, Timsit JF, OUTCOMEREA Study Group
Effect of Transfusion on Mortality and Other Adverse Events Among Critically Ill Septic Patients: An Observational Study Using a Marginal Structural Cox Model.
Critical Care Medicine 2017, 45, 1972-1980.

Mirouse A, Vignon P, Piron P, Robert R, Papazian L, Géri G, Blanc P, Guitton C, Guérin C, Bigé N, Rabbat A, Lefebvre A, Razazi K, Fartoukh M, Mariotte E, Bouadma L, Ricard JD, Seguin A, Souweine B, Moreau AS, Faguer S, Mari A, Mayaux J, Schneider F, Stoclin A, Perez P, Maizel J, Lafon C, Ganster F, Argaud L, Girault C, Barbier F, Lecuyer L, Lambert J, Canet E
Severe varicella-zoster virus pneumonia: a multicenter cohort study.
Critical Care (London, England) 2017, 21, 137.

Garrouste-Orgeas M, Flahault C, Fasse L, Ruckly S, Amdjar-Badidi N, Argaud L, Badie J, Bazire A, Bige N, Boulet E, Bouadma L, Bretonnière C, Floccard B, Gaffinel A, de Forceville X, Grand H, Halidfar R, Hamzaoui O, Jourdain M, Jost PH, Kipnis E, Large A, Lautrette A, Lesieur O, Maxime V, Mercier E, Mira JP, Monseau Y, Parmentier-Decrucq E, Rigaud JP, Rouget A, Santoli F, Simon G, Tamion F, Thieulot-Rolin N, Thirion M, Valade S, Vinatier I, Vioulac C, Bailly S, Timsit JF
The ICU-Diary study: prospective, multicenter comparative study of the impact of an ICU diary on the wellbeing of patients and families in French ICUs.
Trials 2017, 18, 542.

Dupuis C, Sonneville R, Adrie C, Gros A, Darmon M, Bouadma L, Timsit JF
Impact of transfusion on patients with sepsis admitted in intensive care unit: a systematic review and meta-analysis.
Annals of Intensive Care 2017, 7, 5.

Neuville M, El-Helali N, Magalhaes E, Radjou A, Smonig R, Soubirou JF, Voiriot G, Le Monnier A, Ruckly S, Bouadma L, Sonneville R, Timsit JF, Mourvillier B
Systematic overdosing of oxa- and cloxacillin in severe infections treated in ICU: risk factors and side effects.
Annals of Intensive Care 2017, 7, 34.

Timsit JF, Esaied W, Neuville M, Bouadma L, Mourvllier B
Update on ventilator-associated pneumonia.
F1000Research 2017, 6, 2061.

Ibn Saied W, Souweine B, Garrouste-Orgeas M, Ruckly S, Darmon M, Bailly S, Cohen Y, Azoulay E, Schwebel C, Radjou A, Kallel H, Adrie C, Dumenil AS, Argaud L, Marcotte G, Jamali S, Papazian L, Goldgran-Toledano D, Bouadma L, Timsit JF, OUTCOMEREA study group
Respective impact of implementation of prevention strategies, colonization with multiresistant bacteria and antimicrobial use on the risk of early- and late-onset VAP: An analysis of the OUTCOMEREA network.
PloS One 2017, 12, e0187791.

Neuville M, Mourvillier B, Bouadma L, Timsit JF
Bundle of care decreased ventilator-associated events-implications for ventilator-associated pneumonia prevention.
Journal of Thoracic Disease 2017, 9, 430-433.

2016


Mekontso Dessap A, Ware LB, Bouadma L
What's new with biomarker-driven clinical strategy in sepsis and circulatory failure?.
Intensive Care Medicine 2016, 42, 418-421.

Gélisse E, Neuville M, de Montmollin E, Bouadma L, Mourvillier B, Timsit JF, Sonneville R
Extracorporeal membrane oxygenation (ECMO) does not impact on amikacin pharmacokinetics: a case-control study.
Intensive Care Medicine 2016, 42, 946-948.

Truche AS, Darmon M, Bailly S, Clec'h C, Dupuis C, Misset B, Azoulay E, Schwebel C, Bouadma L, Kallel H, Adrie C, Dumenil AS, Argaud L, Marcotte G, Jamali S, Zaoui P, Laurent V, Goldgran-Toledano D, Sonneville R, Souweine B, Timsit JF, OUTCOMEREA Study Group
Continuous renal replacement therapy versus intermittent hemodialysis in intensive care patients: impact on mortality and renal recovery.
Intensive Care Medicine 2016, 42, 1408-1417.

Jensen JU, Bouadma L
Why biomarkers failed in sepsis.
Intensive Care Medicine 2016, 42, 2049-2051.

Sonneville R, Mariotte E, Neuville M, Minaud S, Magalhaes E, Ruckly S, Cantier M, Voiriot G, Radjou A, Smonig R, Soubirou JF, Mourvillier B, Bouadma L, Wolff M, Timsit JF
Early-onset status epilepticus in patients with acute encephalitis.
Medicine 2016, 95, e4092.

Coupez E, Timsit JF, Ruckly S, Schwebel C, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Darmon M, Boyer A, Azoulay E, Bouadma L, Lautrette A, Souweine B
Guidewire exchange vs new site placement for temporary dialysis catheter insertion in ICU patients: is there a greater risk of colonization or dysfunction?.
Critical Care (London, England) 2016, 20, 230.

2015


Lemiale V, Mokart D, Resche-Rigon M, Pène F, Mayaux J, Faucher E, Nyunga M, Girault C, Perez P, Guitton C, Ekpe K, Kouatchet A, Théodose I, Benoit D, Canet E, Barbier F, Rabbat A, Bruneel F, Vincent F, Klouche K, Loay K, Mariotte E, Bouadma L, Moreau AS, Seguin A, Meert AP, Reignier J, Papazian L, Mehzari I, Cohen Y, Schenck M, Hamidfar R, Darmon M, Demoule A, Chevret S, Azoulay E, Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)
Effect of Noninvasive Ventilation vs Oxygen Therapy on Mortality Among Immunocompromised Patients With Acute Respiratory Failure: A Randomized Clinical Trial.
JAMA 2015, 314, 1711-1719.

Bretonnière C, Leone M, Milési C, Allaouchiche B, Armand-Lefevre L, Baldesi O, Bouadma L, Decré D, Figueiredo S, Gauzit R, Guery B, Joram N, Jung B, Lasocki S, Lepape A, Lesage F, Pajot O, Philippart F, Souweine B, Tattevin P, Timsit JF, Vialet R, Zahar JR, Misset B, Bedos JP
Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
Intensive Care Medicine 2015, 41, 1181-1196.

Schortgen F, Charles-Nelson A, Bouadma L, Bizouard G, Brochard L, Katsahian S
Respective impact of lowering body temperature and heart rate on mortality in septic shock: mediation analysis of a randomized trial.
Intensive Care Medicine 2015, 41, 1800-1808.

Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S, Friggeri A, Wallet F, Allou N, Ruckly S, Balayn D, Lepape A, Timsit JF, CLEAN trial investigators
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.
Lancet (London, England) 2015, 386, 2069-2077.

Bouadma L, Sonneville R, Garrouste-Orgeas M, Darmon M, Souweine B, Voiriot G, Kallel H, Schwebel C, Goldgran-Toledano D, Dumenil AS, Argaud L, Ruckly S, Jamali S, Planquette B, Adrie C, Lucet JC, Azoulay E, Timsit JF, OUTCOMEREA Study Group
Ventilator-Associated Events: Prevalence, Outcome, and Relationship With Ventilator-Associated Pneumonia.
Critical Care Medicine 2015, 43, 1798-1806.

Sonneville R, Gault N, de Montmollin E, Klein IF, Mariotte E, Chemam S, Tubach F, Mourvillier B, Timsit JF, Wolff M, Bouadma L
Clinical spectrum and outcomes of patients with encephalitis requiring intensive care.
European Journal of Neurology: The Official Journal of the European Federation of Neurological Societies 2015, 22, 6-16, e1.

Souweine B, Lautrette A, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Guelon D, Darmon M, Vesin A, Caillot N, Schwebel C, Boyer A, Azoulay E, Bouadma L, Timsit JF
Ethanol lock and risk of hemodialysis catheter infection in critically ill patients. A randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2015, 191, 1024-1032.

Bailly S, Bouadma L, Azoulay E, Orgeas MG, Adrie C, Souweine B, Schwebel C, Maubon D, Hamidfar-Roy R, Darmon M, Wolff M, Cornet M, Timsit JF
Failure of empirical systemic antifungal therapy in mechanically ventilated critically ill patients.
American Journal of Respiratory and Critical Care Medicine 2015, 191, 1139-1146.

van Mourik MSM, Bouadma L, Bonten MJM
An old world's view on a new world's solution.
American Journal of Respiratory and Critical Care Medicine 2015, 191, 243-245.

Kutz A, Briel M, Christ-Crain M, Stolz D, Bouadma L, Wolff M, Kristoffersen KB, Wei L, Burkhardt O, Welte T, Schroeder S, Nobre V, Tamm M, Bhatnagar N, Bucher HC, Luyt CE, Chastre J, Tubach F, Mueller B, Schuetz P
Prognostic value of procalcitonin in respiratory tract infections across clinical settings.
Critical Care (London, England) 2015, 19,

Philippart F, Bouroche G, Timsit JF, Garrouste-Orgeas M, Azoulay E, Darmon M, Adrie C, Allaouchiche B, Ara-Somohano C, Ruckly S, Dumenil AS, Souweine B, Goldgran-Toledano D, Bouadma L, Misset B, Outcomerea study group
Decreased Risk of Ventilator-Associated Pneumonia in Sepsis Due to Intra-Abdominal Infection.
PloS One 2015, 10, e0137262.

Schuetz P, Balk R, Briel M, Kutz A, Christ-Crain M, Stolz D, Bouadma L, Wolff M, Kristoffersen KB, Wei L, Burkhardt O, Welte T, Schroeder S, Nobre V, Tamm M, Bhatnagar N, Bucher HC, Luyt CE, Chastre J, Tubach F, Mueller B, Lacey MJ, Ohsfeldt RL, Scheibling CM, Schneider JE
Economic evaluation of procalcitonin-guided antibiotic therapy in acute respiratory infections: a US health system perspective.
Clinical Chemistry and Laboratory Medicine 2015, 53, 583-592.

Loubet P, Lescure FX, Lepage L, Kirsch M, Armand-Lefevre L, Bouadma L, Lariven S, Duval X, Yazdanpanah Y, Joly V
Endocarditis due to gram-negative bacilli at a French teaching hospital over a 6-year period: clinical characteristics and outcome.
Infectious Diseases (London, England) 2015, 47, 889-895.

2014


Schnell D, Timsit JF, Darmon M, Vesin A, Goldgran-Toledano D, Dumenil AS, Garrouste-Orgeas M, Adrie C, Bouadma L, Planquette B, Cohen Y, Schwebel C, Soufir L, Jamali S, Souweine B, Azoulay E
Noninvasive mechanical ventilation in acute respiratory failure: trends in use and outcomes.
Intensive Care Medicine 2014, 40, 582-591.

de Montmollin E, Bouadma L, Gault N, Mourvillier B, Mariotte E, Chemam S, Massias L, Papy E, Tubach F, Wolff M, Sonneville R
Predictors of insufficient amikacin peak concentration in critically ill patients receiving a 25 mg/kg total body weight regimen.
Intensive Care Medicine 2014, 40, 998-1005.

Darmon M, Pichon M, Schwebel C, Ruckly S, Adrie C, Haouache H, Azoulay E, Bouadma L, Clec'h C, Garrouste-Orgeas M, Souweine B, Goldgran-Toledano D, Khallel H, Argaud L, Dumenil AS, Jamali S, Allaouchiche B, Zeni F, Timsit JF
Influence of early dysnatremia correction on survival of critically ill patients.
Shock (Augusta, Ga.) 2014, 41, 394-399.

Timsit JF, Soubirou JF, Voiriot G, Chemam S, Neuville M, Mourvillier B, Sonneville R, Mariotte E, Bouadma L, Wolff M
Treatment of bloodstream infections in ICUs.
BMC infectious diseases 2014, 14, 489.

Tolsma V, Schwebel C, Azoulay E, Darmon M, Souweine B, Vesin A, Goldgran-Toledano D, Lugosi M, Jamali S, Cheval C, Adrie C, Kallel H, Descorps-Declere A, Garrouste-Orgeas M, Bouadma L, Timsit JF
Sepsis severe or septic shock: outcome according to immune status and immunodeficiency profile.
Chest 2014, 146, 1205-1213.

Darmon M, Clec'h C, Adrie C, Argaud L, Allaouchiche B, Azoulay E, Bouadma L, Garrouste-Orgeas M, Haouache H, Schwebel C, Goldgran-Toledano D, Khallel H, Dumenil AS, Jamali S, Souweine B, Zeni F, Cohen Y, Timsit JF
Acute respiratory distress syndrome and risk of AKI among critically ill patients.
Clinical journal of the American Society of Nephrology: CJASN 2014, 9, 1347-1353.

2013


Schuetz P, Müller B, Christ-Crain M, Stolz D, Tamm M, Bouadma L, Luyt CE, Wolff M, Chastre J, Tubach F, Kristoffersen KB, Burkhardt O, Welte T, Schroeder S, Nobre V, Wei L, Bhatnagar N, Bucher HC, Briel M
Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections.
Evidence-Based Child Health: A Cochrane Review Journal 2013, 8, 1297-1371.

Chousterman BG, Bouadma L, Moutereau S, Loric S, Alvarez-Gonzalez A, Mekontso-Dessap A, Laissy JP, Rahmouni A, Katsahian S, Brochard L, Schortgen F
Prevention of contrast-induced nephropathy by N-acetylcysteine in critically ill patients: different definitions, different results.
Journal of Critical Care 2013, 28, 701-709.

Novy E, Sonneville R, Mazighi M, Klein IF, Mariotte E, Mourvillier B, Bouadma L, Wolff M
Neurological complications of infective endocarditis: new breakthroughs in diagnosis and management.
Medecine Et Maladies Infectieuses 2013, 43, 443-450.

Barbier F, Andremont A, Wolff M, Bouadma L
Hospital-acquired pneumonia and ventilator-associated pneumonia: recent advances in epidemiology and management.
Current Opinion in Pulmonary Medicine 2013, 19, 216-228.

Timsit JF, Bouadma L, Mimoz O, Parienti JJ, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Herrault MC, Schwebel C, Ruckly S, Souweine B, Lucet JC
Jugular versus femoral short-term catheterization and risk of infection in intensive care unit patients. Causal analysis of two randomized trials.
American Journal of Respiratory and Critical Care Medicine 2013, 188, 1232-1239.

2012


Schuetz P, Briel M, Christ-Crain M, Stolz D, Bouadma L, Wolff M, Luyt CE, Chastre J, Tubach F, Kristoffersen KB, Wei L, Burkhardt O, Welte T, Schroeder S, Nobre V, Tamm M, Bhatnagar N, Bucher HC, Mueller B
Procalcitonin to guide initiation and duration of antibiotic treatment in acute respiratory infections: an individual patient data meta-analysis.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2012, 55, 651-662.

Quesnel C, Piednoir P, Gelly J, Nardelli L, Garnier M, Leçon V, Lasocki S, Bouadma L, Philip I, Elbim C, Mentré F, Soler P, Crestani B, Dehoux M
Alveolar fibrocyte percentage is an independent predictor of poor outcome in patients with acute lung injury.
Critical Care Medicine 2012, 40, 21–28.

Schwebel C, Lucet JC, Vesin A, Arrault X, Calvino-Gunther S, Bouadma L, Timsit JF
Economic evaluation of chlorhexidine-impregnated sponges for preventing catheter-related infections in critically ill adults in the Dressing Study.
Critical Care Medicine 2012, 40, 11-17.

Timsit JF, Bouadma L, Ruckly S, Schwebel C, Garrouste-Orgeas M, Bronchard R, Calvino-Gunther S, Laupland K, Adrie C, Thuong M, Herault MC, Pease S, Arrault X, Lucet JC
Dressing disruption is a major risk factor for catheter-related infections.
Crit Care Med 2012, 40, 1707-14.

Piednoir P, Quesnel C, Nardelli L, Leçon V, Bouadma L, Lasocki S, Philip I, Mailleux A, Soler P, Crestani B, Dehoux M
Alveolar fluid in acute respiratory distress syndrome promotes fibroblast migration: role of platelet-derived growth factor pathway*.
Critical Care Medicine 2012, 40, 2041-2049.

Bouadma L, Wolff M, Lucet JC
Ventilator-associated pneumonia and its prevention.
Current Opinion in Infectious Diseases 2012, 25, 395-404.

Schortgen F, Clabault K, Katsahian S, Devaquet J, Mercat A, Deye N, Dellamonica J, Bouadma L, Cook F, Beji O, Brun-Buisson C, Lemaire F, Brochard L
Fever control using external cooling in septic shock: a randomized controlled trial.
American Journal of Respiratory and Critical Care Medicine 2012, 185, 1088-1095.

Sonneville R, Schmidt M, Messika J, Ait Hssain A, da Silva D, Klein IF, Bouadma L, Wolff M, Mourvillier B
Neurologic outcomes and adjunctive steroids in HIV patients with severe cerebral toxoplasmosis.
Neurology 2012, 79, 1762-1766.

Bouadma L, Barbier F, Biard L, Esposito-Farèse M, Le Corre B, Macrez A, Salomon L, Bonnal C, Zanker C, Najem C, Mourvillier B, Lucet JC, Régnier B, Wolff M, Tubach F, INFLUENCE-A Study Group
Personal decision-making criteria related to seasonal and pandemic A(H1N1) influenza-vaccination acceptance among French healthcare workers.
PloS One 2012, 7, e38646.

2009


Timsit JF, Schwebel C, Bouadma L, Geffroy A, Garrouste-Orgeas M, Pease S, Herault MC, Haouache H, Calvino-Gunther S, Gestin B, Armand-Lefevre L, Leflon V, Chaplain C, Benali A, Francais A, Adrie C, Zahar JR, Thuong M, Arrault X, Croize J, Lucet JC
Chlorhexidine-impregnated sponges and less frequent dressing changes for prevention of catheter-related infections in critically ill adults: a randomized controlled trial..
JAMA 2009, 301, 1231-1241.

Ruiz S, Papy E, Da Silva D, Nataf P, Massias L, Wolff M, Bouadma L
Potential voriconazole and caspofungin sequestration during extracorporeal membrane oxygenation..
Intensive care medicine 2009, 35, 183-184.

2007


Ricard JD, Wolff M, Lacherade JC, Mourvillier B, Hidri N, Barnaud G, Chevrel G, Bouadma L, Dreyfuss D
Levels of vancomycin in cerebrospinal fluid of adult patients receiving adjunctive corticosteroids to treat pneumococcal meningitis: a prospective multicenter observational study..
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2007, 44, 250-255.

Bouadma L, Dreyfuss D, Ricard JD, Martet G, Saumon G
Mechanical ventilation and hemorrhagic shock-resuscitation interact to increase inflammatory cytokine release in rats..
Critical care medicine 2007, 35, 2601-2606.

2004


Schortgen F, Bouadma L, Joly-Guillou ML, Ricard JD, Dreyfuss D, Saumon G
Infectious and inflammatory dissemination are affected by ventilation strategy in rats with unilateral pneumonia..
Intensive care medicine 2004, 30, 693-701.

Bouadma L, Schortgen F, Ricard JD, Martet G, Dreyfuss D, Saumon G
Ventilation strategy affects cytokine release after mesenteric ischemia-reperfusion in rats..
Critical care medicine 2004, 32, 1563-1569.