Members

  First name: Romain
  Last name: Coppée
  Function: Bioinformatician
  Position: Postdoctoral associate
  Email: romain.coppee
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inserm.fr

Research interest


My primary research focuses on the genomic study of various pathogens.

Education

Degree

2018: Ph.D in bioinformatics – Paris Descartes University

Academic positions

2021-2023: Postdoctoral associate – Paris Cité University – UMR 1137 IAME
2020-2021: Postdoctoral associate – University of Paris – UMR 261 MERIT

List of the main publications

Ferré VM, Bitty-Anderson AM, Peytavin G, Lê MP, Dagnra CA, Coppée R, Gbeasor-Komlanvi FA, Descamps D, Charpentier C, Ekouevi DK
Pharmaco-virological algorithm to target risk of drug resistance among a population of HIV-infected key populations in Togo.
Journal of Medical Virology 2023, 95, e28535.

Piorkowski G, Ghosn J, Coppée R, Mailhé M, Ferré VM, Houhou-Fidouh N, Yazdanpanah Y, Le Hingrat Q, Raoul H, Charpentier C, Descamps D, de Lamballerie X
Genomic diversity of mpox virus in Paris area (France) during the 2022 outbreak.
Journal of Medical Virology 2023, 95, e28853.

Coppée R, Chenane HR, Bridier-Nahmias A, Tcherakian C, Catherinot E, Collin G, Lebourgeois S, Visseaux B, Descamps D, Vasse M, Farfour E
Temporal dynamics of RSV shedding and genetic diversity in adults during the COVID-19 pandemic in a French hospital, early 2021.
Virus Research 2023, 323, 198950.

Coppée R, Sarrasin V, Zaffaroulah R, Bouzayene A, Thellier M, Noël H, Clain J, Houzé S, Investigation Study Group
Nosocomial Malaria Transmissions Resolved by Genomic Analyses-A Retrospective Case Report Study in France: 2007-2021.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2023, 76, 631-639.

Joste V, Colard-Itté E, Guillochon É, Ariey F, Coppée R, Clain J, Houzé S, French National Reference Center for Imported Malaria Study Group
Genetic Profiling of Plasmodium ovale wallikeri Relapses With Microsatellite Markers and Whole-Genome Sequencing.
The Journal of Infectious Diseases 2023, 228, 1089-1098.

Yade MS, Dièye B, Coppée R, Mbaye A, Diallo MA, Diongue K, Bailly J, Mama A, Fall A, Thiaw AB, Ndiaye IM, Ndiaye T, Gaye A, Tine A, Diédhiou Y, Mbaye AM, Doderer-Lang C, Garba MN, Bei AK, Ménard D, Ndiaye D
Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017.
Malaria Journal 2023, 22, 167.

Coppée R, Blanquart F, Jary A, Leducq V, Ferré VM, Franco Yusti AM, Daniel L, Charpentier C, Lebourgeois S, Zafilaza K, Calvez V, Descamps D, Marcelin AG, Visseaux B, Bridier-Nahmias A
Phylodynamics of SARS-CoV-2 in France, Europe, and the world in 2020.
eLife 2023, 12, e82538.

Lebourgeois S, Menidjel R, Chenane HR, Ferré VM, Collin G, Damond F, Coppée R, Yazdanpanah Y, Timsit JF, Houhou-Fidouh N, Descamps D, Charpentier C, Visseaux B
Alpha (B.1.1.7) and Delta (B.1.617.2 - AY.40) SARS-CoV-2 variants present strong neutralization decay at M4 post-vaccination and a faster replication rates than D614G (B.1) lineage.
The Journal of Infection 2022, 84, 418-467.

Coppée R, Bailly J, Sarrasin V, Vianou B, Zinsou BE, Mazars E, Georges H, Hamane S, Lavergne RA, Dannaoui E, Balikagala B, Fukuda N, Odongo-Aginya EI, Mita T, Houzé S, Clain J
Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2022, 75, 1242-1244.

Paloque L, Coppée R, Stokes BH, Gnädig NF, Niaré K, Augereau JM, Fidock DA, Clain J, Benoit-Vical F
Mutation in the Plasmodium falciparum BTB/POZ Domain of K13 Protein Confers Artemisinin Resistance.
Antimicrobial Agents and Chemotherapy 2022, 66, e0132021.

Ferré VM, Peiffer-Smadja N, Kramer L, Coppée R, Kante A, Debarge M, Choquet C, Saint Joannis T, Bouzid D, Messika J, Le Grand J, Thy M, Kernéis S, Descamps D, Visseaux B, Ghosn J
Dual Monoclonal Antibodies on Sars-Cov-2 Alpha and Delta Variants: Clinical and Virological Efficacy.
Microbiology Spectrum 2022, 10, e0215222.

Coppée R, Mama A, Sarrasin V, Kamaliddin C, Adoux L, Palazzo L, Ndam NT, Letourneur F, Ariey F, Houzé S, Clain J
5WBF: a low-cost and straightforward whole blood filtration method suitable for whole-genome sequencing of Plasmodium falciparum clinical isolates.
Malaria Journal 2022, 21, 51.

Lebourgeois S, Chenane HR, Houhou-Fidouh N, Menidjel R, Ferré VM, Collin G, Benmalek N, Coppée R, Larrouy L, Yazdanpanah Y, Timsit JF, Charpentier C, Descamps D, Visseaux B
Earlier In Vitro Viral Production With SARS-CoV-2 Alpha Than With Beta, Gamma, B, or A.27 Variants.
Frontiers in Cellular and Infection Microbiology 2021, 11, 792202.

Coppée R, Sabbagh A, Clain J
Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter.
Scientific Reports 2020, 10, 4842.

Langlois AC, Manzoni G, Vincensini L, Coppée R, Marinach C, Guérin M, Huby T, Carrière V, Cosset FL, Dreux M, Rubinstein E, Silvie O
Molecular determinants of SR-B1-dependent Plasmodium sporozoite entry into hepatocytes.
Scientific Reports 2020, 10, 13509.

Tornyigah B, Coppée R, Houze P, Kusi KA, Adu B, Quakyi I, Coleman N, Mama A, Deloron P, Anang AK, Clain J, Tahar R, Ofori MF, Tuikue Ndam N
Effect of Drug Pressure on Promoting the Emergence of Antimalarial-Resistant Parasites among Pregnant Women in Ghana.
Antimicrobial Agents and Chemotherapy 2020, 64, e02029-19.

Coppée R, Jeffares DC, Miteva MA, Sabbagh A, Clain J
Comparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13.
Scientific Reports 2019, 9, 10675.

Kamaliddin C, Rombaut D, Guillochon E, Royo J, Ezinmegnon S, Agbota G, Huguet S, Guemouri S, Peirera C, Coppée R, Broussard C, Alao JM, Aubouy A, Guillonneau F, Deloron P, Bertin GI
From genomic to LC-MS/MS evidence: Analysis of PfEMP1 in Benin malaria cases.
PloS One 2019, 14, e0218012.

Argy N, Le Gal S, Coppée R, Song Z, Vindrios W, Massias L, Kao WC, Hunte C, Yazdanpanah Y, Lucet JC, Houzé S, Clain J, Nevez G
Pneumocystis Cytochrome b Mutants Associated With Atovaquone Prophylaxis Failure as the Cause of Pneumocystis Infection Outbreak Among Heart Transplant Recipients.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018, 67, 913-919.


Exhaustive list of publications

2023


Ferré VM, Bitty-Anderson AM, Peytavin G, Lê MP, Dagnra CA, Coppée R, Gbeasor-Komlanvi FA, Descamps D, Charpentier C, Ekouevi DK
Pharmaco-virological algorithm to target risk of drug resistance among a population of HIV-infected key populations in Togo.
Journal of Medical Virology 2023, 95, e28535.

Piorkowski G, Ghosn J, Coppée R, Mailhé M, Ferré VM, Houhou-Fidouh N, Yazdanpanah Y, Le Hingrat Q, Raoul H, Charpentier C, Descamps D, de Lamballerie X
Genomic diversity of mpox virus in Paris area (France) during the 2022 outbreak.
Journal of Medical Virology 2023, 95, e28853.

Coppée R, Chenane HR, Bridier-Nahmias A, Tcherakian C, Catherinot E, Collin G, Lebourgeois S, Visseaux B, Descamps D, Vasse M, Farfour E
Temporal dynamics of RSV shedding and genetic diversity in adults during the COVID-19 pandemic in a French hospital, early 2021.
Virus Research 2023, 323, 198950.

Guémas E, Coppée R, Ménard S, du Manoir M, Nsango S, Makaba Mvumbi D, Nakoune E, Eboumbou Moukoko CE, Bouyou Akotet MK, Mirabeau TY, Manguin S, Malekita Yobi D, Akiana J, Kouna LC, Mawili Mboumba DP, Voumbo-Matoumona DF, Otam AL, Rubbo PA, Lombart JP, Kwanai E, Cohen O, Iriart X, Ayong L, Lekana-Douki JB, Ariey F, Berry A
Evolution and spread of Plasmodium falciparum mutations associated with resistance to sulfadoxine-pyrimethamine in central Africa: a cross-sectional study.
The Lancet. Microbe 2023, S2666-5247(23)00211-2.

Coppée R, Sarrasin V, Zaffaroulah R, Bouzayene A, Thellier M, Noël H, Clain J, Houzé S, Investigation Study Group
Nosocomial Malaria Transmissions Resolved by Genomic Analyses-A Retrospective Case Report Study in France: 2007-2021.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2023, 76, 631-639.

Joste V, Colard-Itté E, Guillochon É, Ariey F, Coppée R, Clain J, Houzé S, French National Reference Center for Imported Malaria Study Group
Genetic Profiling of Plasmodium ovale wallikeri Relapses With Microsatellite Markers and Whole-Genome Sequencing.
The Journal of Infectious Diseases 2023, 228, 1089-1098.

Guilbaud R, Franco Yusti AM, Leducq V, Zafilaza K, Bridier-Nahmias A, Todesco E, Soulie C, Fauchois A, Le Hingrat Q, Kramer L, Goulenok T, Salpin M, Daugas E, Dorent R, Ottaviani S, Zalcman G, Ghosn J, Choquet S, Cacoub P, Amoura Z, Barroux B, Pourcher V, Spano JP, Louet M, Marcelin AG, Calvez V, Charpentier C, Descamps D, Marot S, Ferré VM, Coppée R
Higher levels of SARS-CoV-2 genetic variation in immunocompromised patients: a retrospective case-control study.
The Journal of Infectious Diseases 2023, jiad499.

Mazouz F, Bertine M, Coppée R, Storto A, Katlama C, Landman R, Cabié A, Peytavin G, Raffi F, Yazdanpanah Y, Descamps D, Joly V, Ghosn J, Charpentier C, LAMIDOL Study Group
Proportion of APOBEC3-induced defective HIV DNA after 1 year of dolutegravir + lamivudine simplification in the ANRS 167 LAMIDOL trial.
The Journal of Antimicrobial Chemotherapy 2023, dkad344.

Yade MS, Dièye B, Coppée R, Mbaye A, Diallo MA, Diongue K, Bailly J, Mama A, Fall A, Thiaw AB, Ndiaye IM, Ndiaye T, Gaye A, Tine A, Diédhiou Y, Mbaye AM, Doderer-Lang C, Garba MN, Bei AK, Ménard D, Ndiaye D
Ex vivo RSA and pfkelch13 targeted-amplicon deep sequencing reveal parasites susceptibility to artemisinin in Senegal, 2017.
Malaria Journal 2023, 22, 167.

Coppée R, Blanquart F, Jary A, Leducq V, Ferré VM, Franco Yusti AM, Daniel L, Charpentier C, Lebourgeois S, Zafilaza K, Calvez V, Descamps D, Marcelin AG, Visseaux B, Bridier-Nahmias A
Phylodynamics of SARS-CoV-2 in France, Europe, and the world in 2020.
eLife 2023, 12, e82538.

2022


Lebourgeois S, Menidjel R, Chenane HR, Ferré VM, Collin G, Damond F, Coppée R, Yazdanpanah Y, Timsit JF, Houhou-Fidouh N, Descamps D, Charpentier C, Visseaux B
Alpha (B.1.1.7) and Delta (B.1.617.2 - AY.40) SARS-CoV-2 variants present strong neutralization decay at M4 post-vaccination and a faster replication rates than D614G (B.1) lineage.
The Journal of Infection 2022, 84, 418-467.

Coppée R, Bailly J, Sarrasin V, Vianou B, Zinsou BE, Mazars E, Georges H, Hamane S, Lavergne RA, Dannaoui E, Balikagala B, Fukuda N, Odongo-Aginya EI, Mita T, Houzé S, Clain J
Circulation of an Artemisinin-Resistant Malaria Lineage in a Traveler Returning from East Africa to France.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2022, 75, 1242-1244.

Paloque L, Coppée R, Stokes BH, Gnädig NF, Niaré K, Augereau JM, Fidock DA, Clain J, Benoit-Vical F
Mutation in the Plasmodium falciparum BTB/POZ Domain of K13 Protein Confers Artemisinin Resistance.
Antimicrobial Agents and Chemotherapy 2022, 66, e0132021.

Ferré VM, Peiffer-Smadja N, Kramer L, Coppée R, Kante A, Debarge M, Choquet C, Saint Joannis T, Bouzid D, Messika J, Le Grand J, Thy M, Kernéis S, Descamps D, Visseaux B, Ghosn J
Dual Monoclonal Antibodies on Sars-Cov-2 Alpha and Delta Variants: Clinical and Virological Efficacy.
Microbiology Spectrum 2022, 10, e0215222.

Coppée R, Mama A, Sarrasin V, Kamaliddin C, Adoux L, Palazzo L, Ndam NT, Letourneur F, Ariey F, Houzé S, Clain J
5WBF: a low-cost and straightforward whole blood filtration method suitable for whole-genome sequencing of Plasmodium falciparum clinical isolates.
Malaria Journal 2022, 21, 51.

2021


Travert B, Dossier A, Jamme M, Cointe A, Delmas Y, Malot S, Wynckel A, Seguin A, Presne C, Hie M, Benhamou Y, Ribes D, Choukroun G, Grangé S, Hertig A, Le Gall EC, Galicier L, Daugas E, Bouadma L, Weill FX, Azoulay E, Fakhouri F, Veyradier A, Bonacorsi S, Hogan J, Frémeaux-Bacchi V, Rondeau E, Mariani-Kurkdjian P, Coppo P, Centre de Référence des Microangiopathies Thrombotiques2
Shiga Toxin-Associated Hemolytic Uremic Syndrome in Adults, France, 2009-2017.
Emerging Infectious Diseases 2021, 27, 1876-1885.

Lebourgeois S, Chenane HR, Houhou-Fidouh N, Menidjel R, Ferré VM, Collin G, Benmalek N, Coppée R, Larrouy L, Yazdanpanah Y, Timsit JF, Charpentier C, Descamps D, Visseaux B
Earlier In Vitro Viral Production With SARS-CoV-2 Alpha Than With Beta, Gamma, B, or A.27 Variants.
Frontiers in Cellular and Infection Microbiology 2021, 11, 792202.

2020


Coppée R, Sabbagh A, Clain J
Structural and evolutionary analyses of the Plasmodium falciparum chloroquine resistance transporter.
Scientific Reports 2020, 10, 4842.

Langlois AC, Manzoni G, Vincensini L, Coppée R, Marinach C, Guérin M, Huby T, Carrière V, Cosset FL, Dreux M, Rubinstein E, Silvie O
Molecular determinants of SR-B1-dependent Plasmodium sporozoite entry into hepatocytes.
Scientific Reports 2020, 10, 13509.

Tornyigah B, Coppée R, Houze P, Kusi KA, Adu B, Quakyi I, Coleman N, Mama A, Deloron P, Anang AK, Clain J, Tahar R, Ofori MF, Tuikue Ndam N
Effect of Drug Pressure on Promoting the Emergence of Antimalarial-Resistant Parasites among Pregnant Women in Ghana.
Antimicrobial Agents and Chemotherapy 2020, 64, e02029-19.

2019


Coppée R, Jeffares DC, Miteva MA, Sabbagh A, Clain J
Comparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13.
Scientific Reports 2019, 9, 10675.

Kamaliddin C, Rombaut D, Guillochon E, Royo J, Ezinmegnon S, Agbota G, Huguet S, Guemouri S, Peirera C, Coppée R, Broussard C, Alao JM, Aubouy A, Guillonneau F, Deloron P, Bertin GI
From genomic to LC-MS/MS evidence: Analysis of PfEMP1 in Benin malaria cases.
PloS One 2019, 14, e0218012.

2018


Argy N, Le Gal S, Coppée R, Song Z, Vindrios W, Massias L, Kao WC, Hunte C, Yazdanpanah Y, Lucet JC, Houzé S, Clain J, Nevez G
Pneumocystis Cytochrome b Mutants Associated With Atovaquone Prophylaxis Failure as the Cause of Pneumocystis Infection Outbreak Among Heart Transplant Recipients.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2018, 67, 913-919.