Members

  First name: Stephane
  Last name: Ruckly
  Email: stephane.ruckly
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inserm.fr

Research interest



Exhaustive list of publications

2022


Mageau A, Papo T, Ruckly S, Strukov A, van Gysel D, Sacre K, Timsit JF
Survival after COVID-19-associated organ failure among inpatients with systemic lupus erythematosus in France: a nationwide study.
Annals of the Rheumatic Diseases 2022, 81, 569-574.

2021


Buetti N, Souweine B, Mermel L, Mimoz O, Ruckly S, Loiodice A, Mongardon N, Lucet JC, Parienti JJ, Timsit JF
Obesity and risk of catheter-related infections in the ICU. A post hoc analysis of four large randomized controlled trials.
Intensive Care Medicine 2021, 47, 435-443.

Buetti N, Ruckly S, de Montmollin E, Reignier J, Terzi N, Cohen Y, Shiami S, Dupuis C, Timsit JF
COVID-19 increased the risk of ICU-acquired bloodstream infections: a case-cohort study from the multicentric OUTCOMEREA network.
Intensive Care Medicine 2021, 47, 180-187.

Buetti N, Mimoz O, Mermel L, Ruckly S, Mongardon N, Dupuis C, Mira JP, Lucet JC, Mégarbane B, Bailly S, Parienti JJ, Timsit JF
Ultrasound Guidance and Risk for Central Venous Catheter-Related Infections in the Intensive Care Unit: A Post Hoc Analysis of Individual Data of 3 Multicenter Randomized Trials.
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America 2021, 73, e1054-e1061.

Dupuis C, Le Bihan C, Maubon D, Calvet L, Ruckly S, Schwebel C, Bouadma L, Azoulay E, Cornet M, Timsit JF, ESG
Performance of Repeated Measures of (1-3)-β-D-Glucan, Mannan Antigen, and Antimannan Antibodies for the Diagnosis of Invasive Candidiasis in ICU Patients: A Preplanned Ancillary Analysis of the EMPIRICUS Randomized Clinical Trial.
Open Forum Infectious Diseases 2021, 8, ofab080.

Dupuis C, Bouadma L, de Montmollin E, Goldgran-Toledano D, Schwebel C, Reignier J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Grapin K, Laurent V, Buetti N, Gainnier M, Souweine B, Timsit JF
Association Between Early Invasive Mechanical Ventilation and Day-60 Mortality in Acute Hypoxemic Respiratory Failure Related to Coronavirus Disease-2019 Pneumonia.
Critical Care Explorations 2021, 3, e0329.

de Montmollin E, Schwebel C, Dupuis C, Garrouste-Orgeas M, da Silva D, Azoulay E, Laurent V, Thiéry G, Grinea A, Marcotte G, Oziel J, Gainnier M, Siami S, Reignier J, Sztrymf B, Adrie C, Ruckly S, Sonneville R, Timsit JF
Life Support Limitations in Mechanically Ventilated Stroke Patients.
Critical Care Explorations 2021, 3, e0341.

Legouy C, Girard-Stein L, Wanono R, de Montmollin E, Vellieux G, Bouadma L, Dupuis C, Abid S, Vinclair C, Ruckly S, Rouvel-Tallec A, d'Ortho MP, Timsit JF, Sonneville R
Association of Standard Electroencephalography Findings With Mortality and Command Following in Mechanically Ventilated Patients Remaining Unresponsive After Sedation Interruption.
Critical Care Medicine 2021, 49, e423-e432.

Buetti N, Mimoz O, Schwebel C, Ruckly S, Castry M, Dupuis C, Souweine B, Lucet JC, Timsit JF
Insertion Site and Infection Risk among Peripheral Arterial Catheters.
American Journal of Respiratory and Critical Care Medicine 2021, 203, 630-633.

Gheerbrant H, Timsit JF, Terzi N, Ruckly S, Laramas M, Levra MG, Jacquet E, Falque L, Moro-Sibilot D, Toffart AC
Factors associated with survival of patients with solid Cancer alive after intensive care unit discharge between 2005 and 2013.
BMC cancer 2021, 21, 9.

Buetti N, Ruckly S, Lucet JC, Mimoz O, Souweine B, Timsit JF
Factors influencing local signs at catheter insertion site regardless of catheter-related bloodstream infections.
Critical Care (London, England) 2021, 25, 71.

Meyer A, Buetti N, Houhou-Fidouh N, Patrier J, Abdel-Nabey M, Jaquet P, Presente S, Girard T, Sayagh F, Ruckly S, Wicky PH, de Montmollin E, Bouadma L, Sonneville R, Descamps D, Timsit JF
HSV-1 reactivation is associated with an increased risk of mortality and pneumonia in critically ill COVID-19 patients.
Critical Care (London, England) 2021, 25, 417.

Buetti N, Ruckly S, Lucet JC, Mageau A, Dupuis C, Souweine B, Mimoz O, Timsit JF
Practices and intravascular catheter infection during on- and off-hours in critically ill patients.
Annals of Intensive Care 2021, 11, 153.

d'Humières C, Patrier J, Lortat-Jacob B, Tran-Dinh A, Chemali L, Maataoui N, Rondinaud E, Ruppé E, Burdet C, Ruckly S, Montravers P, Timsit JF, Armand-Lefevre L
Two original observations concerning bacterial infections in COVID-19 patients hospitalized in intensive care units during the first wave of the epidemic in France.
PloS One 2021, 16, e0250728.

Papin G, Bailly S, Dupuis C, Ruckly S, Gainnier M, Argaud L, Azoulay E, Adrie C, Souweine B, Goldgran-Toledano D, Marcotte G, Gros A, Reignier J, Mourvillier B, Forel JM, Sonneville R, Dumenil AS, Darmon M, Garrouste-Orgeas M, Schwebel C, Timsit JF, Osg
Clinical and biological clusters of sepsis patients using hierarchical clustering.
PloS One 2021, 16, e0252793.

Dupuis C, de Montmollin E, Buetti N, Goldgran-Toledano D, Reignier J, Schwebel C, Domitile J, Neuville M, Ursino M, Siami S, Ruckly S, Alberti C, Mourvillier B, Bailly S, Laurent V, Gainnier M, Souweine B, Timsit JF, Orn
Impact of early corticosteroids on 60-day mortality in critically ill patients with COVID-19: A multicenter cohort study of the OUTCOMEREA network.
PloS One 2021, 16, e0255644.

Ursino M, Dupuis C, Buetti N, de Montmollin E, Bouadma L, Golgran-Toledano D, Ruckly S, Neuville M, Cohen Y, Mourvillier B, Souweine B, Gainnier M, Laurent V, Terzi N, Shiami S, Reignier J, Alberti C, Timsit JF, On Behalf Of The Outcomerea Study Group n
Multistate Modeling of COVID-19 Patients Using a Large Multicentric Prospective Cohort of Critically Ill Patients.
Journal of Clinical Medicine 2021, 10,

2020


Andremont O, Armand-Lefevre L, Dupuis C, de Montmollin E, Ruckly S, Lucet JC, Smonig R, Magalhaes E, Ruppé E, Mourvillier B, Lebut J, Lermuzeaux M, Sonneville R, Bouadma L, Timsit JF, Cnc
Semi-quantitative cultures of throat and rectal swabs are efficient tests to predict ESBL-Enterobacterales ventilator-associated pneumonia in mechanically ventilated ESBL carriers.
Intensive Care Medicine 2020, 46, 1232-1242.

Sonneville R, Mazighi M, Bresson D, Crassard I, Crozier S, de Montmollin E, Degos V, Faugeras F, Gayat E, Josse L, Lamy C, Magalhaes E, Maldjian A, Ruckly S, Servan J, Vassel P, Vigué B, Timsit JF, Woimant F, Si
Outcomes of Acute Stroke Patients Requiring Mechanical Ventilation: Study Protocol for the SPICE Multicenter Prospective Observational Study.
Neurocritical Care 2020, 32, 624-629.

Magalhaes E, Reuter J, Wanono R, Bouadma L, Jaquet P, Tanaka S, Sinnah F, Ruckly S, Dupuis C, de Montmollin E, Para M, Braham W, Pisani A, d'Ortho MP, Rouvel-Tallec A, Timsit JF, Sonneville R, Dsg
Early EEG for Prognostication Under Venoarterial Extracorporeal Membrane Oxygenation.
Neurocritical Care 2020, 33, 688-694.

Buetti N, Souweine B, Mermel L, Mimoz O, Ruckly S, Loiodice A, Mongardon N, Lucet JC, Parienti JJ, Timsit JF
Concurrent systemic antibiotics at catheter insertion and intravascular catheter-related infection in the ICU: a post hoc analysis using individual data from five large RCTs.
Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2020

Bailly S, Galerneau LM, Ruckly S, Seiller A, Terzi N, Schwebel C, Dupuis C, Tamisier R, Mourvillier B, Pepin JL, Timsit JF
Impact of obstructive sleep apnea on the obesity paradox in critically ill patients.
Journal of Critical Care 2020, 56, 120-124.

Ibn Saied W, Merceron S, Schwebel C, Le Monnier A, Oziel J, Garrouste-Orgeas M, Marcotte G, Ruckly S, Souweine B, Darmon M, Bouadma L, de Montmollin E, Mourvillier B, Reignier J, Papazian L, Siami S, Azoulay E, Bédos JP, Timsit JF
Ventilator-associated pneumonia due to Stenotrophomonas maltophilia: Risk factors and outcome.
The Journal of Infection 2020, 80, 279-285.

Reuter J, Peoc'h K, Bouadma L, Ruckly S, Chicha-Cattoir V, Faille D, Bourrienne MC, Dupuis C, Magalhaes E, Tanaka S, Vinclair C, de Montmollin E, Mazighi M, Para M, Braham W, Pisani A, Ajzenberg N, Timsit JF, Sonneville R
Neuron-Specific Enolase Levels in Adults Under Venoarterial Extracorporeal Membrane Oxygenation.
Critical Care Explorations 2020, 2, e0239.

Buetti N, Ruckly S, Lucet JC, Perozziello A, Mimoz O, Souweine B, Timsit JF
The Insertion Site Should Be Considered for the Empirical Therapy of Short-Term Central Venous and Arterial Catheter-Related Infections.
Critical Care Medicine 2020, 48, 739-744.

Buetti N, Ruckly S, Schwebel C, Mimoz O, Souweine B, Lucet JC, Timsit JF
Chlorhexidine-impregnated sponge versus chlorhexidine gel dressing for short-term intravascular catheters: which one is better?.
Critical Care (London, England) 2020, 24, 458.

Buetti N, Wicky PH, Le Hingrat Q, Ruckly S, Mazzuchelli T, Loiodice A, Trimboli P, Forni Ogna V, de Montmollin E, Bernasconi E, Visseaux B, Timsit JF
SARS-CoV-2 detection in the lower respiratory tract of invasively ventilated ARDS patients.
Critical Care (London, England) 2020, 24, 610.

Buetti N, Ruckly S, Lucet JC, Bouadma L, Garrouste-Orgeas M, Schwebel C, Mimoz O, Souweine B, Timsit JF
Local signs at insertion site and catheter-related bloodstream infections: an observational post hoc analysis using individual data of four RCTs.
Critical Care (London, England) 2020, 24, 694.

Vinclair C, De Montmollin E, Sonneville R, Reuter J, Lebut J, Cally R, Mourvillier B, Neuville M, Ruckly S, Timsit JF, Bouadma L
Factors associated with major adverse kidney events in patients who underwent veno-arterial extracorporeal membrane oxygenation.
Annals of Intensive Care 2020, 10, 44.

OSG, de Montmollin E, Terzi N, Dupuis C, Garrouste-Orgeas M, da Silva D, Darmon M, Laurent V, Thiéry G, Oziel J, Marcotte G, Gainnier M, Siami S, Sztrymf B, Adrie C, Reignier J, Ruckly S, Sonneville R, Timsit JF
One-year survival in acute stroke patients requiring mechanical ventilation: a multicenter cohort study.
Annals of Intensive Care 2020, 10, 53.

Buetti N, Ruckly S, Lucet JC, Bouadma L, Schwebel C, Mimoz O, Timsit JF
Ultrasound guidance and risk for intravascular catheter-related infections among peripheral arterial catheters: a post-hoc analysis of two large randomized-controlled trials.
Annals of Intensive Care 2020, 10, 89.

Elabbadi A, Pichon J, Visseaux B, Schnuriger A, Bouadma L, Philippot Q, Patrier J, Labbé V, Ruckly S, Fartoukh M, Timsit JF, Voiriot G
Respiratory virus-associated infections in HIV-infected adults admitted to the intensive care unit for acute respiratory failure: a 6-year bicenter retrospective study (HIV-VIR study).
Annals of Intensive Care 2020, 10, 123.

Dupuis C, Bouadma L, Ruckly S, Perozziello A, Van-Gysel D, Mageau A, Mourvillier B, de Montmollin E, Bailly S, Papin G, Sinnah F, Vinclair C, Abid S, Sonneville R, Timsit JF
Sepsis and septic shock in France: incidences, outcomes and costs of care.
Annals of Intensive Care 2020, 10, 145.

2019


Garrouste-Orgeas M, Flahault C, Vinatier I, Rigaud JP, Thieulot-Rolin N, Mercier E, Rouget A, Grand H, Lesieur O, Tamion F, Hamidfar R, Renault A, Parmentier-Decrucq E, Monseau Y, Argaud L, Bretonnière C, Lautrette A, Badié J, Boulet E, Floccard B, Forceville X, Kipnis E, Soufir L, Valade S, Bige N, Gaffinel A, Hamzaoui O, Simon G, Thirion M, Bouadma L, Large A, Mira JP, Amdjar-Badidi N, Jourdain M, Jost PH, Maxime V, Santoli F, Ruckly S, Vioulac C, Leborgne MA, Bellalou L, Fasse L, Misset B, Bailly S, Timsit JF
Effect of an ICU Diary on Posttraumatic Stress Disorder Symptoms Among Patients Receiving Mechanical Ventilation: A Randomized Clinical Trial.
JAMA 2019, 322, 229-239.

Timsit JF, Citerio G, Lavilloniere M, Perner A, Ruckly S, Bakker J, Bassetti M, Benoit D, Curtis JR, Doig GS, Herridge M, Jaber S, Papazian L, Peters MJ, Singer P, Smith M, Soares M, Torres A, Vieillard-Baron A, Azoulay E
Determinants of downloads and citations for articles published in Intensive Care Medicine.
Intensive Care Medicine 2019, 45, 1058-1060.

Pons S, Timsit JF, Ruckly S, Schwebel C, Papazian L, Azoulay E, Reignier J, Zafrani L
Impact of macrolide therapy in critically ill patients with acute respiratory failure: a desirability of outcome ranking analysis to investigate the OUTCOMEREA database.
Intensive Care Medicine 2019

Timsit JF, Schwebel C, Styfalova L, Cornet M, Poirier P, Forrestier C, Ruckly S, Jacob MC, Souweine B
Impact of bronchial colonization with Candida spp. on the risk of bacterial ventilator-associated pneumonia in the ICU: the FUNGIBACT prospective cohort study.
Intensive Care Medicine 2019, 45, 834-843.

Buetti N, Ruckly S, Lucet JC, Mimoz O, Souweine B, Timsit JF
Short-term dialysis catheter versus central venous catheter infections in ICU patients: a post hoc analysis of individual data of 4 multi-centric randomized trials.
Intensive Care Medicine 2019

Mageau A, Timsit JF, Perrozziello A, Ruckly S, Dupuis C, Bouadma L, Papo T, Sacre K
The burden of chronic kidney disease in systemic lupus erythematosus: A nationwide epidemiologic study.
Autoimmunity Reviews 2019, 18, 733-737.

Mageau A, Sacré K, Perozziello A, Ruckly S, Dupuis C, Bouadma L, Papo T, Timsit JF
Septic shock among patients with systemic lupus erythematosus: short and long-term outcome. Analysis of a French nationwide database.
The Journal of Infection 2019

de Montmollin E, Ruckly S, Schwebel C, Philippart F, Adrie C, Mariotte E, Marcotte G, Cohen Y, Sztrymf B, da Silva D, Bruneel F, Gainnier M, Garrouste-Orgeas M, Sonneville R, Timsit JF, OSG
Pneumonia in acute ischemic stroke patients requiring invasive ventilation: Impact on short and long-term outcomes.
The Journal of Infection 2019, 79, 220-227.

Lattuca-Truc M, Timsit JF, Levra MG, Ruckly S, Villa J, Dumas I, Pinsolle J, Ferrer L, Guillem P, Moro-Sibilot D, Toffart AC
Trends in response rate and survival in small-cell lung cancer patients between 1997 and 2017.
Lung Cancer 2019, 131, 122-127.

Ibn Saied W, Mourvillier B, Cohen Y, Ruckly S, Reignier J, Marcotte G, Siami S, Bouadma L, Darmon M, de Montmollin E, Argaud L, Kallel H, Garrouste-Orgeas M, Soufir L, Schwebel C, Souweine B, Glodgran-Toledano D, Papazian L, Timsit JF
A Comparison of the Mortality Risk Associated With Ventilator-Acquired Bacterial Pneumonia and Nonventilator ICU-Acquired Bacterial Pneumonia*:.
Critical Care Medicine 2019, 47, 345-352.

Boisson M, Corbi P, Kerforne T, Camilleri L, Debauchez M, Demondion P, Eljezi V, Flecher E, Lepelletier D, Leprince P, Nesseler N, Nizou JY, Roussel JC, Rozec B, Ruckly S, Lucet JC, Timsit JF, Mimoz O
Multicentre, open-label, randomised, controlled clinical trial comparing 2% chlorhexidine-70% isopropanol and 5% povidone iodine-69% ethanol for skin antisepsis in reducing surgical-site infection after cardiac surgery: the CLEAN 2 study protocol.
BMJ open 2019, 9, e026929.

Garrouste-Orgeas M, Flahault C, Poulain E, Evin A, Guirimand F, Fossez-Diaz V, Perruchio S, Verlaine C, Vanbésien A, Kaczmarek W, Birkui de Francqueville L, De Larivière E, Bouquet G, Copel L, Verliac V, Marché V, Mathias C, Gracia D, Mhalla A, Michonneau-Gandon V, Poupardin C, Touzet L, Ranchou G, Guastella V, Richard B, Bienfait F, Sonrier M, Michel D, Ruckly S, Bailly S, Timsit JF
The Fami-life study: protocol of a prospective observational multicenter mixed study of psychological consequences of grieving relatives in French palliative care units on behalf of the family research in palliative care (F.R.I.P.C research network).
BMC Palliative Care 2019, 18, 111.

Morvan AC, Garrouste-Orgeas M, Ruckly S, Forel JM, Argaud L, Rimmelé T, Bedos JP, Azoulay E, Dupuis C, Mourvillier B, Schwebel C, Timsit JF
Impact of species and antibiotic therapy of enterococcal peritonitis on 30-day mortality in critical care—an analysis of the OUTCOMEREA database.
Critical Care 2019, 23, 307.

Pons S, Sonneville R, Bouadma L, Styfalova L, Ruckly S, Neuville M, Radjou A, Lebut J, Dilly MP, Mourvillier B, Dorent R, Nataf P, Wolff M, Timsit JF
Infectious complications following heart transplantation in the era of high-priority allocation and extracorporeal membrane oxygenation.
Annals of Intensive Care 2019, 9, 17.

2018


Bluhmki T, Allignol A, Ruckly S, Timsit JF, Wolkewitz M, Beyersmann J
Estimation of adjusted expected excess length-of-stay associated with ventilation-acquired pneumonia in intensive care: A multistate approach accounting for time-dependent mechanical ventilation.
Biometrical Journal. Biometrische Zeitschrift 2018, 60, 1135-1150.

Azoulay E, Lemiale V, Mourvillier B, Garrouste-Orgeas M, Schwebel C, Ruckly S, Argaud L, Cohen Y, Souweine B, Papazian L, Reignier J, Marcotte G, Siami S, Kallel H, Darmon M, Timsit JF, OSG
Management and outcomes of acute respiratory distress syndrome patients with and without comorbid conditions.
Intensive Care Medicine 2018

Puntillo KA, Max A, Timsit JF, Ruckly S, Chanques G, Robleda G, Roche-Campo F, Mancebo J, Divatia JV, Soares M, Ionescu DC, Grintescu IM, Maggiore SM, Rusinova K, Owczuk R, Egerod I, Papathanassoglou EDE, Kyranou M, Joynt GM, Burghi G, Freebairn RC, Ho KM, Kaarlola A, Gerritsen RT, Kesecioglu J, Sulaj MMS, Norrenberg M, Benoit DD, Seha MSG, Hennein A, Pereira FJ, Benbenishty JS, Abroug F, Aquilina A, Monte JRC, An Y, Azoulay E
Pain distress: the negative emotion associated with procedures in ICU patients.
Intensive Care Medicine 2018, 44, 1493-1501.

Garrouste-Orgeas M, Azoulay E, Ruckly S, Schwebel C, de Montmollin E, Bedos JP, Souweine B, Marcotte G, Adrie C, Goldgran-Toledano D, Dumenil AS, Kallel H, Jamali S, Argaud L, Darmon M, Zahar JR, Timsit JF
Diabetes was the only comorbid condition associated with mortality of invasive pneumococcal infection in ICU patients: a multicenter observational study from the Outcomerea research group.
Infection 2018, 46, 669-677.

Sommer H, Timsit JF, von Cube M, Schumacher M, Darmon M, Schwebel C, Ruckly S, Wolkewitz M, CMC
The Impact of Early Adequate Treatment on Extubation and Discharge Alive of Patients With Pseudomonas aeruginosa-Related Ventilator-Associated Pneumonia.
Critical Care Medicine 2018, 46, 1643-1648.

Gros A, Dupuis C, Ruckly S, Lautrette A, Garrouste-Orgeas M, Gainnier M, Forel JM, Marcotte G, Azoulay E, Cohen Y, Schwebel C, Argaud L, de Montmollin E, Siami S, Goldgran-Toledano D, Darmon M, Timsit JF, OSG
Association Between Body Weight Variation and Survival and Other Adverse Events in Critically Ill Patients With Shock: A Multicenter Cohort Study of the OUTCOMEREA Network.
Critical Care Medicine 2018, 46, e981-e987.

Cantier M, Morisot A, Guérot E, Megarbane B, Razazi K, Contou D, Mariotte E, Canet E, De Montmollin E, Dubée V, Boulet E, Gaudry S, Voiriot G, Mayaux J, Pène F, Neuville M, Mourvillier B, Ruckly S, Bouadma L, Wolff M, Timsit JF, Sonneville R, Esg
Functional outcomes in adults with tuberculous meningitis admitted to the ICU: a multicenter cohort study.
Critical Care (London, England) 2018, 22, 210.

2017


Sonneville R, de Montmollin E, Poujade J, Garrouste-Orgeas M, Souweine B, Darmon M, Mariotte E, Argaud L, Barbier F, Goldgran-Toledano D, Marcotte G, Dumenil AS, Jamali S, Lacave G, Ruckly S, Mourvillier B, Timsit JF
Potentially modifiable factors contributing to sepsis-associated encephalopathy.
Intensive Care Medicine 2017, 43, 1075-1084.

Zahar JR, Lesprit P, Ruckly S, Eden A, Hikombo H, Bernard L, Harbarth S, Timsit JF, Brun-Buisson C, BSG
Predominance of healthcare-associated cases among episodes of community-onset bacteraemia due to extended-spectrum β-lactamase-producing Enterobacteriaceae.
International Journal of Antimicrobial Agents 2017, 49, 67-73.

Zahar JR, Lesprit P, Ruckly S, Eden A, Hikombo H, Bernard L, Harbarth S, Timsit JF, Brun-Buisson C, BSG
Erratum to 'Predominance of healthcare-associated cases among episodes of community-onset bacteraemia due to extended-spectrum β-lactamase-producing Enterobacteriaceae' [International Journal of Antimicrobial Agents 49/1 67-73].
International Journal of Antimicrobial Agents 2017, 49, 480-481.

Adrie C, Garrouste-Orgeas M, Ibn Essaied W, Schwebel C, Darmon M, Mourvillier B, Ruckly S, Dumenil AS, Kallel H, Argaud L, Marcotte G, Barbier F, Laurent V, Goldgran-Toledano D, Clec'h C, Azoulay E, Souweine B, Timsit JF, OSG
Attributable mortality of ICU-acquired bloodstream infections: Impact of the source, causative micro-organism, resistance profile and antimicrobial therapy.
The Journal of Infection 2017, 74, 131-141.

Baldesi O, Bailly S, Ruckly S, Lepape A, L'Heriteau F, Aupee M, Boussat S, Bervas C, Machut A, Berger-Carbonne A, Savey A, Timsit JF, RRn
ICU-acquired candidaemia in France: Epidemiology and temporal trends, 2004-2013 - A study from the REA-RAISIN network.
The Journal of Infection 2017, 75, 59-67.

Jullien V, Azoulay E, Schwebel C, Le Saux T, Charles PE, Cornet M, Souweine B, Klouche K, Jaber S, Trouillet JL, Bruneel F, Cour M, Cousson J, Meziani F, Gruson D, Paris A, Darmon M, Garrouste-Orgeas M, Navellou JC, Foucrier A, Allaouchiche B, Das V, Gangneux JP, Ruckly S, Wolff M, Timsit JF, ETSG
Population pharmacokinetics of micafungin in ICU patients with sepsis and mechanical ventilation.
The Journal of Antimicrobial Chemotherapy 2017, 72, 181-189.

Dupuis C, Garrouste-Orgeas M, Bailly S, Adrie C, Goldgran-Toledano D, Azoulay E, Ruckly S, Marcotte G, Souweine B, Darmon M, Cohen Y, Schwebel C, Lacave G, Bouadma L, Timsit JF, OSG
Effect of Transfusion on Mortality and Other Adverse Events Among Critically Ill Septic Patients: An Observational Study Using a Marginal Structural Cox Model.
Critical Care Medicine 2017, 45, 1972-1980.

de Montmollin E, Demeret S, Brulé N, Conrad M, Dailler F, Lerolle N, Navellou JC, Schwebel C, Alves M, Cour M, Engrand N, Tonnelier JM, Maury E, Ruckly S, Picard G, Rogemond V, Magalhaes É, Sharshar T, Timsit JF, Honnorat J, Sonneville R, ESG‡
Anti-N-Methyl-d-Aspartate Receptor Encephalitis in Adult Patients Requiring Intensive Care.
American Journal of Respiratory and Critical Care Medicine 2017, 195, 491-499.

Viglino D, Vesin A, Ruckly S, Morelli X, Slama R, Debaty G, Danel V, Maignan M, Timsit JF
Daily volume of cases in emergency call centers: construction and validation of a predictive model.
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2017, 25, 86.

Terzi N, Darmon M, Reignier J, Ruckly S, Garrouste-Orgeas M, Lautrette A, Azoulay E, Mourvillier B, Argaud L, Papazian L, Gainnier M, Goldgran-Toledano D, Jamali S, Dumenil AS, Schwebel C, Timsit JF, Osg
Initial nutritional management during noninvasive ventilation and outcomes: a retrospective cohort study.
Critical Care (London, England) 2017, 21, 293.

Garrouste-Orgeas M, Flahault C, Fasse L, Ruckly S, Amdjar-Badidi N, Argaud L, Badie J, Bazire A, Bige N, Boulet E, Bouadma L, Bretonnière C, Floccard B, Gaffinel A, de Forceville X, Grand H, Halidfar R, Hamzaoui O, Jourdain M, Jost PH, Kipnis E, Large A, Lautrette A, Lesieur O, Maxime V, Mercier E, Mira JP, Monseau Y, Parmentier-Decrucq E, Rigaud JP, Rouget A, Santoli F, Simon G, Tamion F, Thieulot-Rolin N, Thirion M, Valade S, Vinatier I, Vioulac C, Bailly S, Timsit JF
The ICU-Diary study: prospective, multicenter comparative study of the impact of an ICU diary on the wellbeing of patients and families in French ICUs.
Trials 2017, 18, 542.

Adrie C, Lugosi M, Sonneville R, Souweine B, Ruckly S, Cartier JC, Garrouste-Orgeas M, Schwebel C, Timsit JF, Osg
Persistent lymphopenia is a risk factor for ICU-acquired infections and for death in ICU patients with sustained hypotension at admission.
Annals of Intensive Care 2017, 7, 30.

Neuville M, El-Helali N, Magalhaes E, Radjou A, Smonig R, Soubirou JF, Voiriot G, Le Monnier A, Ruckly S, Bouadma L, Sonneville R, Timsit JF, Mourvillier B
Systematic overdosing of oxa- and cloxacillin in severe infections treated in ICU: risk factors and side effects.
Annals of Intensive Care 2017, 7, 34.

Azoulay E, Timsit JF, Lautrette A, Legriel S, Max A, Ruckly S, Misset B, Cohen Y, Wolff M
Weekly high-dose liposomal amphotericin B (L-AmB) in critically ill septic patients with multiple Candida colonization: The AmBiDex study.
PloS One 2017, 12, e0177093.

Ibn Saied W, Souweine B, Garrouste-Orgeas M, Ruckly S, Darmon M, Bailly S, Cohen Y, Azoulay E, Schwebel C, Radjou A, Kallel H, Adrie C, Dumenil AS, Argaud L, Marcotte G, Jamali S, Papazian L, Goldgran-Toledano D, Bouadma L, Timsit JF, Osg
Respective impact of implementation of prevention strategies, colonization with multiresistant bacteria and antimicrobial use on the risk of early- and late-onset VAP: An analysis of the OUTCOMEREA network.
PloS One 2017, 12, e0187791.

2016


Timsit JF, Azoulay E, Schwebel C, Charles PE, Cornet M, Souweine B, Klouche K, Jaber S, Trouillet JL, Bruneel F, Argaud L, Cousson J, Meziani F, Gruson D, Paris A, Darmon M, Garrouste-Orgeas M, Navellou JC, Foucrier A, Allaouchiche B, Das V, Gangneux JP, Ruckly S, Maubon D, Jullien V, Wolff M, ETG
Empirical Micafungin Treatment and Survival Without Invasive Fungal Infection in Adults With ICU-Acquired Sepsis, Candida Colonization, and Multiple Organ Failure: The EMPIRICUS Randomized Clinical Trial.
JAMA 2016, 316, 1555-1564.

Weiss E, Zahar JR, Garrouste-Orgeas M, Ruckly S, Essaied W, Schwebel C, Timsit JF, OSG
De-escalation of pivotal beta-lactam in ventilator-associated pneumonia does not impact outcome and marginally affects MDR acquisition.
Intensive Care Medicine 2016, 42, 2098-2100.

Günther SC, Schwebel C, Hamidfar-Roy R, Bonadona A, Lugosi M, Ara-Somohano C, Minet C, Potton L, Cartier JC, Vésin A, Chautemps M, Styfalova L, Ruckly S, Timsit JF
Complications of intravascular catheters in ICU: definitions, incidence and severity. A randomized controlled trial comparing usual transparent dressings versus new-generation dressings (the ADVANCED study).
Intensive Care Medicine 2016, 42, 1753-1765.

Njamkepo E, Fawal N, Tran-Dien A, Hawkey J, Strockbine N, Jenkins C, Talukder KA, Bercion R, Kuleshov K, Kolínská R, Russell JE, Kaftyreva L, Accou-Demartin M, Karas A, Vandenberg O, Mather AE, Mason CJ, Page AJ, Ramamurthy T, Bizet C, Gamian A, Carle I, Sow AG, Bouchier C, Wester AL, Lejay-Collin M, Fonkoua MC, Hello SL, Blaser MJ, Jernberg C, Ruckly C, Mérens A, Page AL, Aslett M, Roggentin P, Fruth A, Denamur E, Venkatesan M, Bercovier H, Bodhidatta L, Chiou CS, Clermont D, Colonna B, Egorova S, Pazhani GP, Ezernitchi AV, Guigon G, Harris SR, Izumiya H, Korzeniowska-Kowal A, Lutyńska A, Gouali M, Grimont F, Langendorf C, Marejková M, Peterson LAM, Perez-Perez G, Ngandjio A, Podkolzin A, Souche E, Makarova M, Shipulin GA, Ye C, Žemličková H, Herpay M, Grimont PAD, Parkhill J, Sansonetti P, Holt KE, Brisse S, Thomson NR, Weill FX
Global phylogeography and evolutionary history of Shigella dysenteriae type 1.
Nature Microbiology 2016, 1, 16027.

Barbier F, Pommier C, Essaied W, Garrouste-Orgeas M, Schwebel C, Ruckly S, Dumenil AS, Lemiale V, Mourvillier B, Clec'h C, Darmon M, Laurent V, Marcotte G, Lucet JC, Souweine B, Zahar JR, Timsit JF, OSG
Colonization and infection with extended-spectrum β-lactamase-producing Enterobacteriaceae in ICU patients: what impact on outcomes and carbapenem exposure?.
The Journal of Antimicrobial Chemotherapy 2016, 71, 1088-1097.

Garrouste-Orgeas M, Max A, Lerin T, Grégoire C, Ruckly S, Kloeckner M, Brochon S, Pichot E, Simons C, El-Mhadri M, Bruel C, Philippart F, Fournier J, Tiercelet K, Timsit JF, Misset B
Impact of Proactive Nurse Participation in ICU Family Conferences: A Mixed-Method Study.
Critical Care Medicine 2016, 44, 1116-1128.

Sonneville R, Mariotte E, Neuville M, Minaud S, Magalhaes E, Ruckly S, Cantier M, Voiriot G, Radjou A, Smonig R, Soubirou JF, Mourvillier B, Bouadma L, Wolff M, Timsit JF
Early-onset status epilepticus in patients with acute encephalitis.
Medicine 2016, 95, e4092.

Paiva JA, Pereira JM, Tabah A, Mikstacki A, de Carvalho FB, Koulenti D, Ruckly S, Çakar N, Misset B, Dimopoulos G, Antonelli M, Rello J, Ma X, Tamowicz B, Timsit JF
Characteristics and risk factors for 28-day mortality of hospital acquired fungemias in ICUs: data from the EUROBACT study.
Critical Care (London, England) 2016, 20,

Coupez E, Timsit JF, Ruckly S, Schwebel C, Gruson D, Canet E, Klouche K, Argaud L, Bohe J, Garrouste-Orgeas M, Mariat C, Vincent F, Cayot S, Cointault O, Lepape A, Darmon M, Boyer A, Azoulay E, Bouadma L, Lautrette A, Souweine B
Guidewire exchange vs new site placement for temporary dialysis catheter insertion in ICU patients: is there a greater risk of colonization or dysfunction?.
Critical Care (London, England) 2016, 20, 230.

Voiriot G, Visseaux B, Cohen J, Nguyen LB, Neuville M, Morbieu C, Burdet C, Radjou A, Lescure FX, Smonig R, Armand-Lefevre L, Mourvillier B, Yazdanpanah Y, Soubirou JF, Ruckly S, Houhou-Fidouh N, Timsit JF
Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia.
Crit Care 2016, 20, 375.

Garrouste-Orgeas M, Ruckly S, Grégoire C, Dumesnil AS, Pommier C, Jamali S, Golgran-Toledano D, Schwebel C, Clec'h C, Soufir L, Fartoukh M, Marcotte G, Argaud L, Verdière B, Darmon M, Azoulay E, Timsit JF
Treatment intensity and outcome of nonagenarians selected for admission in ICUs: a multicenter study of the Outcomerea Research Group.
Annals of Intensive Care 2016, 6, 31.

2015


Reignier J, Darmon M, Sonneville R, Borel AL, Garrouste-Orgeas M, Ruckly S, Souweine B, Dumenil AS, Haouache H, Adrie C, Argaud L, Soufir L, Marcotte G, Laurent V, Goldgran-Toledano D, Clec'h C, Schwebel C, Azoulay E, Timsit JF
Impact of early nutrition and feeding route on outcomes of mechanically ventilated patients with shock: a post hoc marginal structural model study.
Intensive Care Medicine 2015, 41, 875-886.

Lautrette A, Garrouste-Orgeas M, Bertrand PM, Goldgran-Toledano D, Jamali S, Laurent V, Argaud L, Schwebel C, Mourvillier B, Darmon M, Ruckly S, Dumenil AS, Lemiale V, Souweine B, Timsit JF, OSG
Respective impact of no escalation of treatment, withholding and withdrawal of life-sustaining treatment on ICU patients' prognosis: a multicenter study of the Outcomerea Research Group.
Intensive Care Medicine 2015, 41, 1763-1772.

Mimoz O, Lucet JC, Kerforne T, Pascal J, Souweine B, Goudet V, Mercat A, Bouadma L, Lasocki S, Alfandari S, Friggeri A, Wallet F, Allou N, Ruckly S, Balayn D, Lepape A, Timsit JF, Cti
Skin antisepsis with chlorhexidine-alcohol versus povidone iodine-alcohol, with and without skin scrubbing, for prevention of intravascular-catheter-related infection (CLEAN): an open-label, multicentre, randomised, controlled, two-by-two factorial trial.
Lancet (London, England) 2015, 386, 2069-2077.

Bouadma L, Sonneville R, Garrouste-Orgeas M, Darmon M, Souweine B, Voiriot G, Kallel H, Schwebel C, Goldgran-Toledano D, Dumenil AS, Argaud L, Ruckly S, Jamali S, Planquette B, Adrie C, Lucet JC, Azoulay E, Timsit JF, OSG
Ventilator-Associated Events: Prevalence, Outcome, and Relationship With Ventilator-Associated Pneumonia.
Critical Care Medicine 2015, 43, 1798-1806.

Maunoury F, Motrunich A, Palka-Santini M, Bernatchez SF, Ruckly S, Timsit JF
Cost-Effectiveness Analysis of a Transparent Antimicrobial Dressing for Managing Central Venous and Arterial Catheters in Intensive Care Units.
PloS One 2015, 10, e0130439.

Philippart F, Bouroche G, Timsit JF, Garrouste-Orgeas M, Azoulay E, Darmon M, Adrie C, Allaouchiche B, Ara-Somohano C, Ruckly S, Dumenil AS, Souweine B, Goldgran-Toledano D, Bouadma L, Misset B, Osg
Decreased Risk of Ventilator-Associated Pneumonia in Sepsis Due to Intra-Abdominal Infection.
PloS One 2015, 10, e0137262.

2014


Debaty G, Maignan M, Savary D, Koch FX, Ruckly S, Durand M, Picard J, Escallier C, Chouquer R, Santre C, Minet C, Guergour D, Hammer L, Bouvaist H, Belle L, Adrie C, Payen JF, Carpentier F, Gueugniaud PY, Danel V, Timsit JF
Impact of intra-arrest therapeutic hypothermia in outcomes of prehospital cardiac arrest: a randomized controlled trial.
Intensive Care Medicine 2014, 40, 1832-1842.

Garrouste-Orgeas M, Ben-Rehouma M, Darmon M, Ruckly S, Clec'h C, Adrie C, Tabah A, Vesin A, Schwebel C, Misset B, Timsit JF
ICU physician-based determinants of life-sustaining therapy during nights and weekends: French multicenter study from the Outcomerea Research Group.
Critical Care Medicine 2014, 42, 2393-2400.

Darmon M, Pichon M, Schwebel C, Ruckly S, Adrie C, Haouache H, Azoulay E, Bouadma L, Clec'h C, Garrouste-Orgeas M, Souweine B, Goldgran-Toledano D, Khallel H, Argaud L, Dumenil AS, Jamali S, Allaouchiche B, Zeni F, Timsit JF
Influence of early dysnatremia correction on survival of critically ill patients.
Shock (Augusta, Ga.) 2014, 41, 394-399.

2013


Vesin A, Azoulay E, Ruckly S, Vignoud L, Rusinovà K, Benoit D, Soares M, Azeivedo-Maia P, Abroug F, Benbenishty J, Timsit JF
Reporting and handling missing values in clinical studies in intensive care units.
Intensive Care Medicine 2013, 39, 1396-1404.

Schwebel C, Clec'h C, Magne S, Minet C, Garrouste-Orgeas M, Bonadona A, Dumenil AS, Jamali S, Kallel H, Goldgran-Toledano D, Marcotte G, Azoulay E, Darmon M, Ruckly S, Souweine B, Timsit JF
Safety of Intrahospital Transport in Ventilated Critically Ill Patients: A Multicenter Cohort Study.
Critical Care Medicine 2013, 41, 1919-1928.

Timsit JF, Bouadma L, Mimoz O, Parienti JJ, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Herrault MC, Schwebel C, Ruckly S, Souweine B, Lucet JC
Jugular versus femoral short-term catheterization and risk of infection in intensive care unit patients. Causal analysis of two randomized trials.
American Journal of Respiratory and Critical Care Medicine 2013, 188, 1232-1239.

Darmon M, Diconne E, Souweine B, Ruckly S, Adrie C, Azoulay E, Clec'h C, Garrouste-Orgeas M, Schwebel C, Goldgran-Toledano D, Khallel H, Dumenil AS, Jamali S, Cheval C, Allaouchiche B, Zeni F, Timsit JF
Prognostic consequences of borderline dysnatremia: pay attention to minimal serum sodium change.
Critical Care (London, England) 2013, 17, R12.

2012


Timsit JF, L'Hériteau F, Lepape A, Francais A, Ruckly S, Venier AG, Jarno P, Boussat S, Coignard B, Savey A
A multicentre analysis of catheter-related infection based on a hierarchical model.
Intensive Care Medicine 2012, 38, 1662-1672.

Timsit JF, Bouadma L, Ruckly S, Schwebel C, Garrouste-Orgeas M, Bronchard R, Calvino-Gunther S, Laupland K, Adrie C, Thuong M, Herault MC, Pease S, Arrault X, Lucet JC
Dressing disruption is a major risk factor for catheter-related infections.
Crit Care Med 2012, 40, 1707-14.

Minet C, Lugosi M, Savoye PY, Menez C, Ruckly S, Bonadona A, Schwebel C, Hamidfar-Roy R, Dumanoir P, Ara-Somohano C, Ferretti GR, Timsit JF
Pulmonary embolism in mechanically ventilated patients requiring computed tomography: Prevalence, risk factors, and outcome.
Critical Care Medicine 2012, 40, 3202-3208.

Timsit JF, Mimoz O, Mourvillier B, Souweine B, Garrouste-Orgeas M, Alfandari S, Plantefeve G, Bronchard R, Troche G, Gauzit R, Antona M, Canet E, Bohe J, Lepape A, Vesin A, Arrault X, Schwebel C, Adrie C, Zahar JR, Ruckly S, Tournegros C, Lucet JC
Randomized controlled trial of chlorhexidine dressing and highly adhesive dressing for preventing catheter-related infections in critically ill adults.
American Journal of Respiratory and Critical Care Medicine 2012, 186, 1272-1278.