Research interest

I am a research scientist in biostatistics/pharmacometrics at the French Institute of Health & Medical Research (Inserm), specialized in infectious diseases and antiviral treatment. My researches have theoretical objectives, such as developing mathematical models to understand quantitative aspects of host/pathogen interaction. They also aim to impact clinical research by optimizing drug combination, dosing regimen and identify characteristics associated with a differential response to antiviral treatment.

My researches have initially focused on chronic viral infections (HIV, HBV, HCV) and have progressively shifted to acute emerging viral infections (SARS-CoV-2, viral hemorrhagic fever). I also apply the models and the statistical methods developed in virus dynamics to other fields of research, in particular bacterial dynamics (microbiota, phage therapy) and cancer.
I work in the INSERM IAME laboratory devoted to infectious diseases, and located on the premises of Hospital Bichat campus, in the north of Paris. Within IAME, I am leading a group named MOCLID devoted to modeling and clinical investigation in infectious diseases, gathering about 50 scientists, medical doctors and young researchers.