Intranet
Thi Huyen Tram Nguyen | IAME
Thi Huyen Tram Nguyen - Former member -

Publications

Modeling Favipiravir Antiviral Efficacy Against Emerging Viruses: From Animal Studies to Clinical Trials

2020

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PubMed

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CPT: pharmacometrics & systems pharmacology

Madelain V et al.Madelain V, Mentré F, Baize S, Anglaret X, Laouénan C, Oestereich L, Nguyen THT, Malvy D, Piorkowski G, Graw F, Günther S, Raoul H, de Lamballerie X, Guedj J

Viral kinetics analysis and virological characterization of treatment failures in patients with chronic hepatitis C treated with sofosbuvir and an NS5A inhibitor

2018

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PubMed

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Alimentary Pharmacology & Therapeutics

Fourati S et al.Fourati S, Guedj J, Chevaliez S, Nguyen THT, Roudot-Thoraval F, Ruiz I, Soulier A, Scoazec G, Varaut A, Poiteau L, Francois M, Mallat A, Hézode C, Pawlotsky JM

Antiviral efficacy of favipiravir against Ebola virus: A translational study in cynomolgus macaques

2018

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PLoS Med

Guedj J et al.Guedj J, Piorkowski G, Jacquot F, Madelain V, Nguyen THT, Rodallec A, Gunther S, Carbonnelle C, Mentre F, Raoul H, de Lamballerie X

Favipiravir Pharmacokinetics in Nonhuman Primates and Insights for Future Efficacy Studies of Hemorrhagic Fever Viruses

2017

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Antimicrobial Agents and Chemotherapy

Madelain V et al.Madelain V, Guedj J, Mentré F, Nguyen THT, Jacquot F, Oestereich L, Kadota T, Yamada K, Taburet AM, de Lamballerie X, Raoul H

Individual Bayesian Information Matrix for Predicting Estimation Error and Shrinkage of Individual Parameters Accounting for Data Below the Limit of Quantification

2017

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Pharm Res

Nguyen THT et al.Nguyen THT, Nguyen TT, Mentre F

The paradox of highly effective sofosbuvir-based combination therapy despite slow viral decline: can we still rely on viral kinetics?

2017

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PubMed

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Scientific Reports

Nguyen THT et al.Nguyen THT, Guedj J, Uprichard SL, Kohli A, Kottilil S, Perelson AS

Determining Ribavirin's mechanism of action against Lassa virus infection

2017

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PubMed

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Scientific Reports

Carrillo-Bustamante P et al.Carrillo-Bustamante P, Nguyen THT, Oestereich L, Günther S, Guedj J, Graw F

Improvement of ALT decay kinetics by all-oral HCV treatment: Role of NS5A inhibitors and differences with IFN-based regimens

2017

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PubMed

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PloS One

Cento V et al.Cento V, Nguyen THT, Di Carlo D, Biliotti E, Gianserra L, Lenci I, Di Paolo D, Calvaruso V, Teti E, Cerrone M, Romagnoli D, Melis M, Danieli E, Menzaghi B, Polilli E, Siciliano M, Nicolini LA, Di Biagio A, Magni CF, Bolis M, Antonucci FP, Di Maio VC, Alfieri R, Sarmati L, Casalino P, Bernardini S, Micheli V, Rizzardini G, Parruti G, Quirino T, Puoti M, Babudieri S, D'Arminio Monforte A, Andreoni M, Craxì A, Angelico M, Pasquazzi C, Taliani G, Guedj J, Perno CF, Ceccherini-Silberstein F

Persistence and clearance of Ebola virus RNA from seminal fluid of Ebola virus disease survivors: a longitudinal analysis and modelling study

2017

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PubMed

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The Lancet. Global Health

Sissoko D et al.Sissoko D, Duraffour S, Kerber R, Kolie JS, Beavogui AH, Camara AM, Colin G, Rieger T, Oestereich L, Pályi B, Wurr S, Guedj J, Nguyen THT, Eggo RM, Watson CH, Edmunds WJ, Bore JA, Koundouno FR, Cabeza-Cabrerizo M, Carter LL, Kafetzopoulou LE, Kuisma E, Michel J, Patrono LV, Rickett NY, Singethan K, Rudolf M, Lander A, Pallasch E, Bockholt S, Rodríguez E, Di Caro A, Wölfel R, Gabriel M, Gurry C, Formenty P, Keïta S, Malvy D, Carroll MW, Anglaret X, Günther S

Can we use viral kinetic models to individualize treatment?

2015

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Liver International: Official Journal of the International Association for the Study of the Liver

Guedj J et al.Guedj J, Nguyen THT

Ebola virus dynamics in mice treated with favipiravir

2015

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Antiviral Research

Madelain V et al.Madelain V, Oestereich L, Graw F, Nguyen THT, de Lamballerie X, Mentré F, Günther S, Guedj J

A pharmacokinetic-viral kinetic model describes the effect of alisporivir as monotherapy or in combination with peg-IFN on hepatitis C virologic response

2014

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Clinical Pharmacology and Therapeutics

Nguyen THT et al.Nguyen THT, Mentré F, Levi M, Yu J, Guedj J

Influence of a priori Information, Designs, and Undetectable Data on Individual Parameters Estimation and Prediction of Hepatitis C Treatment Outcome

2013

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CPT: pharmacometrics & systems pharmacology

Nguyen THT et al.Nguyen THT, Guedj J, Yu J, Levi M, Mentré F

Extension of NPDE for evaluation of nonlinear mixed effect models in presence of data below the quantification limit with applications to HIV dynamic model

2012

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Journal of Pharmacokinetics and Pharmacodynamics

Nguyen THT et al.Nguyen THT, Comets E, Mentré F